Oleanolic acid supplement attenuates liquid fructose-induced adipose tissue insulin resistance through the insulin receptor substrate-1/phosphatidylinositol 3-kinase/Akt signaling pathway in rats

Toxicology and Applied Pharmacology

Volumn 277, Issue 2, 2014, Pages 155-163

  Li, Ying ^a   Wang, Jianwei ^a   Gu, Tieguang ^b   Yamahara, Johji ^c   Li, Yuhao ^b  

^a CHONGQING MEDICAL UNIVERSITY   (China)

^b Sydney Institute of Health Sciences   (Australia)

^c Pharmafood Institute   (Japan)

Author keywords

Adipose tissue; Fatty acid; Fructose; Insulin receptor substrate; Insulin resistance; Oleanolic acid

Indexed keywords

FATTY ACID; FRUCTOSE; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; MESSENGER RNA; OLEANOLIC ACID; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SERINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIET SUPPLEMENTATION; ENZYME PHOSPHORYLATION; FATTY ACID BLOOD LEVEL; GENE EXPRESSION; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; MALE; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; TREATMENT DURATION; UPREGULATION; WHITE ADIPOSE TISSUE;

ADIPOSE TISSUE; FATTY ACID; FRUCTOSE; INSULIN RECEPTOR SUBSTRATE; INSULIN RESISTANCE; OLEANOLIC ACID;

ADIPOSE TISSUE; ANIMALS; BIOLOGICAL MARKERS; DIETARY SUPPLEMENTS; DISEASE MODELS, ANIMAL; ENERGY METABOLISM; FATTY ACIDS, NONESTERIFIED; FRUCTOSE; GLUCOSE TOLERANCE TEST; INSULIN; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN RESISTANCE; MALE; OLEANOLIC ACID; PHOSPHATIDYLINOSITOL 3-KINASE; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 84899157465     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2014.03.016     Document Type: Article

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