메뉴 건너뛰기




Volumn 145, Issue 6, 2005, Pages 767-774

Pomegranate flower improves cardiac lipid metabolism in a diabetic rat model: Role of lowering circulating lipids

Author keywords

Diabetes; Fatty acid; Gene; Lipid metabolism; Myocardium; Oxidation; PPAR ; Punica granatum

Indexed keywords

3 [3 TERT BUTYLTHIO 1 (4 CHLOROBENZYL) 5 ISOPROPYL 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; 4 O METHYLPHORBOL 13 ACETATE 12 MYRISTATE; 5' ADENOSINE MONOPHOSPHATE ACTIVATED PROTEIN KINASE 2; ACYL COENZYME A OXIDASE; CARNITINE PALMITOYLTRANSFERASE; CARRIER PROTEIN; CHOLESTEROL; FATTY ACID; FENOFIBRATE; GALLIC ACID; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MESSENGER RNA; OLEANOLIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PUNICA GRANATUM EXTRACT; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

EID: 23044510556     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706245     Document Type: Article
Times cited : (125)

References (39)
  • 3
    • 12544259675 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptor alpha increases the expression and activity of microsomal triglyceride transfer protein in the liver
    • AMEEN, C., EDVARDSSON, U., LJUNGBERG, A., ASP, L., AKERBLAD, P., TUNELD, A., OLOFSSON, S.O., LINDEN, D. & OSCARSSON, J. (2005). Activation of peroxisome proliferator-activated receptor alpha increases the expression and activity of microsomal triglyceride transfer protein in the liver. J. Biol. Chem., 280, 1224-1229.
    • (2005) J. Biol. Chem. , vol.280 , pp. 1224-1229
    • Ameen, C.1    Edvardsson, U.2    Ljungberg, A.3    Asp, L.4    Akerblad, P.5    Tuneld, A.6    Olofsson, S.O.7    Linden, D.8    Oscarsson, J.9
  • 9
    • 0034678088 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors: Insight into multiple cellular functions
    • ESCHER, P. & WAHLI, W. (2000). Peroxisome proliferator-activated receptors: insight into multiple cellular functions. Mutat Res., 448, 121-138.
    • (2000) Mutat Res. , vol.448 , pp. 121-138
    • Escher, P.1    Wahli, W.2
  • 10
    • 4644359293 scopus 로고    scopus 로고
    • Concentrated pomegranate juice improves lipid profiles in diabetic patients with hyperlipidemia
    • ESMAILLZADEH, A., TAHBAZ, F., GAIENI, I., ALAVI-MAJD, H. & AZADBAKHT, L. (2004). Concentrated pomegranate juice improves lipid profiles in diabetic patients with hyperlipidemia. J. Med. Food, 7, 305-308.
    • (2004) J. Med. Food , vol.7 , pp. 305-308
    • Esmaillzadeh, A.1    Tahbaz, F.2    Gaieni, I.3    Alavi-Majd, H.4    Azadbakht, L.5
  • 14
    • 0033788223 scopus 로고    scopus 로고
    • Antioxidant activity of pomegranate juice and its relationship with phenolic composition and processing
    • GIL, M.I., TOMAS-BARBERAN, F.A., HESS-PIERCE, B., HOLCROFT, D.M. & KADER, A.A. (2000). Antioxidant activity of pomegranate juice and its relationship with phenolic composition and processing. J. Agric. Food. Chem., 48, 4581-4589.
    • (2000) J. Agric. Food. Chem. , vol.48 , pp. 4581-4589
    • Gil, M.I.1    Tomas-Barberan, F.A.2    Hess-Pierce, B.3    Holcroft, D.M.4    Kader, A.A.5
  • 15
    • 23044467570 scopus 로고    scopus 로고
    • Anti-diabetic action of Punica granatum flower extract: Activation of PPAR-γ and identification of an active component
    • in press
    • HUANG, T.H., PENG, G., KOTA, B.P., LI, Q., YAMAHARA, J., ROUFOGALIS, BD. & LI, Y. (2005). Anti-diabetic action of Punica granatum flower extract: activation of PPAR-γ and identification of an active component. Toxcol. Appl. Pharm., in press.
    • (2005) Toxcol. Appl. Pharm.
    • Huang, T.H.1    Peng, G.2    Kota, B.P.3    Li, Q.4    Yamahara, J.5    Roufogalis, B.D.6    Li, Y.7
  • 16
    • 0034662490 scopus 로고    scopus 로고
    • Effect of Punica granatum Linn., (flowers) on blood glucose level in normal and alloxan-induced diabetic rats
    • JAFRI, M.A., ASLAM, M., JAVED, K. & SINGH, S. (2000). Effect of Punica granatum Linn., (flowers) on blood glucose level in normal and alloxan-induced diabetic rats. J. Ethnopharmacol., 70, 309-314.
    • (2000) J. Ethnopharmacol. , vol.70 , pp. 309-314
    • Jafri, M.A.1    Aslam, M.2    Javed, K.3    Singh, S.4
  • 17
    • 0032911531 scopus 로고    scopus 로고
    • Inhibition of cytochrome P450 2E1 expression by oleanolic acid: Hepatoprotective effects against carbon tetrachloride-induced hepatic injury
    • JEONG, H.G. (1999). Inhibition of cytochrome P450 2E1 expression by oleanolic acid: hepatoprotective effects against carbon tetrachloride-induced hepatic injury. Toxicol. Lett., 105, 215-222.
    • (1999) Toxicol. Lett. , vol.105 , pp. 215-222
    • Jeong, H.G.1
  • 18
    • 0342329930 scopus 로고
    • Lucknow: Munshi Nawal Kishore (Urdu translation)
    • JURJANI, M.I. (1878). Zakheera-Khwarzam-Shahi. Lucknow: Munshi Nawal Kishore. 540 (Urdu translation).
    • (1878) Zakheera-Khwarzam-Shahi , pp. 540
    • Jurjani, M.I.1
  • 21
    • 0041820128 scopus 로고    scopus 로고
    • Differential influences of peroxisome proliferator-activated receptors gamma and -alpha on food intake and energy homeostasis
    • LARSEN, P.J., JENSEN, P.B., SORENSEN, R.V., LARSEN, L.K., VRANG, N., WULFF, E.M. & WASSERMANN, K. (2003). Differential influences of peroxisome proliferator-activated receptors gamma and -alpha on food intake and energy homeostasis. Diabetes, 52, 224922-224959.
    • (2003) Diabetes , vol.52 , pp. 224922-224959
    • Larsen, P.J.1    Jensen, P.B.2    Sorensen, R.V.3    Larsen, L.K.4    Vrang, N.5    Wulff, E.M.6    Wassermann, K.7
  • 22
    • 19444377479 scopus 로고    scopus 로고
    • Punica granatum flower extract, a potent α-glucosidase inhibitor, improves postprandial hyperglycemia in Zucker diabetic fatty rats
    • in press
    • LI, Y., WEN, S., KOTA, B.P., PENG, G., LI, Q., YAMAHARA, J. & ROUFOGALIS, B.D. (2005). Punica granatum flower extract, a potent α-glucosidase inhibitor, improves postprandial hyperglycemia in Zucker diabetic fatty rats. J. Ethnopharmacol., in press.
    • (2005) J. Ethnopharmacol.
    • Li, Y.1    Wen, S.2    Kota, B.P.3    Peng, G.4    Li, Q.5    Yamahara, J.6    Roufogalis, B.D.7
  • 23
    • 0029567968 scopus 로고
    • Pharmacology of oleanolic acid and ursolic acid
    • LIU, J. (1995). Pharmacology of oleanolic acid and ursolic acid. J. Ethnopharmacol., 49, 57-68.
    • (1995) J. Ethnopharmacol. , vol.49 , pp. 57-68
    • Liu, J.1
  • 24
    • 0029617925 scopus 로고
    • Effect of oleanolic acid on hepatic toxicant-activating and detoxifying systems in mice
    • LIU, J., LIU, Y., PARKINSON, A. & KLAASSEN, C.D. (1995). Effect of oleanolic acid on hepatic toxicant-activating and detoxifying systems in mice. J. Pharmacol. Exp. Ther., 275, 768-774.
    • (1995) J. Pharmacol. Exp. Ther. , vol.275 , pp. 768-774
    • Liu, J.1    Liu, Y.2    Parkinson, A.3    Klaassen, C.D.4
  • 25
    • 0036278903 scopus 로고    scopus 로고
    • Metabolic abnormalities in the diabetic heart
    • LOPASCHUK, G.D. (2002). Metabolic abnormalities in the diabetic heart. Heart, Fail. Rev., 1, 149-159.
    • (2002) Heart, Fail. Rev. , vol.1 , pp. 149-159
    • Lopaschuk, G.D.1
  • 26
    • 0343635008 scopus 로고
    • Lucknow: Munshi Nawal Kishore Urdu translation
    • MAJOOSI, A.I.A. (1889). Kamilussanah. Lucknow: Munshi Nawal Kishore. 145 Urdu translation.
    • (1889) Kamilussanah , pp. 145
    • Majoosi, A.I.A.1
  • 28
    • 0037178848 scopus 로고    scopus 로고
    • Overexpression of apolipoprotein B in the heart impedes cardiac triglyceride accumulation and development of cardiac dysfunction in diabetic mice
    • NIELSEN, L.B., BARTELS, E.D. & BOLLANO, E. (2002). Overexpression of apolipoprotein B in the heart impedes cardiac triglyceride accumulation and development of cardiac dysfunction in diabetic mice. J. Biol. Chem., 277, 27014-27020.
    • (2002) J. Biol. Chem. , vol.277 , pp. 27014-27020
    • Nielsen, L.B.1    Bartels, E.D.2    Bollano, E.3
  • 29
    • 0035029876 scopus 로고    scopus 로고
    • Thiazolidinediones increase plasma-adipose tissue FFA exchange capacity and enhance insulin-mediated control of systemic FFA availability
    • OAKES, N.D., THALEN, P.G., JACINTO, S.M. & LJUNG, B. (2001). Thiazolidinediones increase plasma-adipose tissue FFA exchange capacity and enhance insulin-mediated control of systemic FFA availability. Diabetes, 50, 1158-1165.
    • (2001) Diabetes , vol.50 , pp. 1158-1165
    • Oakes, N.D.1    Thalen, P.G.2    Jacinto, S.M.3    Ljung, B.4
  • 30
    • 0141699719 scopus 로고    scopus 로고
    • Quantitative determination of hydroxy pentacyclic triterpene acids in vegetable oils
    • PEREZ-CAMINO, M.C. & CERT, A. (1999). Quantitative determination of hydroxy pentacyclic triterpene acids in vegetable oils. J. Agric. Food. Chem., 47, 1558-1562.
    • (1999) J. Agric. Food. Chem. , vol.47 , pp. 1558-1562
    • Perez-Camino, M.C.1    Cert, A.2
  • 31
    • 0031934256 scopus 로고    scopus 로고
    • Metabolic disturbances in diabetic cardiomyopathy
    • RODRIGUES, B., CAM, M.C. & MCNEILL, J.H. (1998). Metabolic disturbances in diabetic cardiomyopathy. Mol. Cell Biochem., 180, 53-57.
    • (1998) Mol. Cell Biochem. , vol.180 , pp. 53-57
    • Rodrigues, B.1    Cam, M.C.2    Mcneill, J.H.3
  • 32
    • 0028152492 scopus 로고
    • Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein
    • SCHAFFER, J.E. & LODISH, H.F. (1994). Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein. Cell, 79, 427-436.
    • (1994) Cell , vol.79 , pp. 427-436
    • Schaffer, J.E.1    Lodish, H.F.2
  • 33
    • 0036884292 scopus 로고    scopus 로고
    • A novel mechanism for the inhibition of NF-kappaB activation in vascular endothelial cells by natural antioxidants
    • SCHUBERT, S.Y., NEEMAN, I. & RESNICK, N. (2002). A novel mechanism for the inhibition of NF-kappaB activation in vascular endothelial cells by natural antioxidants. FASEB J., 16, 1931-1933.
    • (2002) FASEB J. , vol.16 , pp. 1931-1933
    • Schubert, S.Y.1    Neeman, I.2    Resnick, N.3
  • 34
    • 0342506484 scopus 로고    scopus 로고
    • Regulation of energy substrate metabolism in the diabetic heart
    • STANLEY, W.C., LOPASCHUK, G.D. & MCCORMACK, J.G. (1997). Regulation of energy substrate metabolism in the diabetic heart. Cardiovasc. Res., 34, 25-33.
    • (1997) Cardiovasc. Res. , vol.34 , pp. 25-33
    • Stanley, W.C.1    Lopaschuk, G.D.2    Mccormack, J.G.3
  • 35
    • 0035993444 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor agonists, hyperlipidaemia, and atherosclerosis
    • VOSPER, H., KHOUDOLI, G.A., GRAHAM, T.L. & PALMER, C.N. (2002). Peroxisome proliferator-activated receptor agonists, hyperlipidaemia, and atherosclerosis. Pharmacol. Ther., 95, 47-62.
    • (2002) Pharmacol. Ther. , vol.95 , pp. 47-62
    • Vosper, H.1    Khoudoli, G.A.2    Graham, T.L.3    Palmer, C.N.4
  • 36
    • 33544457439 scopus 로고    scopus 로고
    • The impact of altered substrate utilization on cardiac function in isolated hearts from Zucker diabetic fatty rats
    • in press
    • WANG, P.G., LLOYD, S.G., ZENG, H., BONEN, A. & CHATHAM, J.C. (2004). The impact of altered substrate utilization on cardiac function in isolated hearts from Zucker diabetic fatty rats. Am. J. Physiol. Heart. Circ. Physiol., in press.
    • (2004) Am. J. Physiol. Heart. Circ. Physiol.
    • Wang, P.G.1    Lloyd, S.G.2    Zeng, H.3    Bonen, A.4    Chatham, J.C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.