메뉴 건너뛰기




Volumn 19, Issue 4, 2014, Pages 514-523

Biomolecular markers in assessment and treatment of asthma

Author keywords

asthma; biomarker; eosinophil; inflammation; molecular targeted therapy

Indexed keywords

BIOLOGICAL MARKER; CORTICOSTEROID; MOLECULAR MARKER; NITRIC OXIDE; ANTIINFLAMMATORY AGENT;

EID: 84899125098     PISSN: 13237799     EISSN: 14401843     Source Type: Journal    
DOI: 10.1111/resp.12284     Document Type: Review
Times cited : (27)

References (101)
  • 2
    • 67049144615 scopus 로고    scopus 로고
    • Eosinophilic and neutrophilic inflammation in asthma: Insights from clinical studies
    • Fahy JV,. Eosinophilic and neutrophilic inflammation in asthma: insights from clinical studies. Proc. Am. Thorac. Soc. 2009; 6: 256-259.
    • (2009) Proc. Am. Thorac. Soc. , vol.6 , pp. 256-259
    • Fahy, J.V.1
  • 3
    • 84867060673 scopus 로고    scopus 로고
    • Biomarkers of inflammation in asthma: A clinical perspective
    • Taylor DR,. Biomarkers of inflammation in asthma: a clinical perspective. Semin. Respir. Crit. Care Med. 2012; 33: 620-629.
    • (2012) Semin. Respir. Crit. Care Med. , vol.33 , pp. 620-629
    • Taylor, D.R.1
  • 5
    • 84858322573 scopus 로고    scopus 로고
    • Clinical update on the use of biomarkers of airway inflammation in the management of asthma
    • Wadsworth S, Sin D, Dorscheid D,. Clinical update on the use of biomarkers of airway inflammation in the management of asthma. J. Asthma. Allergy. 2011; 4: 77-86.
    • (2011) J. Asthma. Allergy. , vol.4 , pp. 77-86
    • Wadsworth, S.1    Sin, D.2    Dorscheid, D.3
  • 6
    • 33646338915 scopus 로고    scopus 로고
    • Breath analysis: Potential for clinical diagnosis and exposure assessment
    • Cao W, Duan Y,. Breath analysis: potential for clinical diagnosis and exposure assessment. Clin. Chem. 2006; 52: 800-811.
    • (2006) Clin. Chem. , vol.52 , pp. 800-811
    • Cao, W.1    Duan, Y.2
  • 8
    • 34548012407 scopus 로고    scopus 로고
    • Effect of an inducible nitric oxide synthase inhibitor on differential flow-exhaled nitric oxide in asthmatic patients and healthy volunteers
    • Brindicci C, Ito K, Barnes PJ, Kharitonov SA,. Effect of an inducible nitric oxide synthase inhibitor on differential flow-exhaled nitric oxide in asthmatic patients and healthy volunteers. Chest 2007; 132: 581-588.
    • (2007) Chest , vol.132 , pp. 581-588
    • Brindicci, C.1    Ito, K.2    Barnes, P.J.3    Kharitonov, S.A.4
  • 9
    • 0027479429 scopus 로고
    • Reactive nitrogen intermediates and antimicrobial activity: Role of nitrite
    • Klebanoff SJ,. Reactive nitrogen intermediates and antimicrobial activity: role of nitrite. Free Radic. Biol. Med. 1993; 14: 351-360.
    • (1993) Free Radic. Biol. Med. , vol.14 , pp. 351-360
    • Klebanoff, S.J.1
  • 10
    • 17644363081 scopus 로고    scopus 로고
    • ATS/ERS recommendations for standardized procedures for the online and offline measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide, 2005
    • American Thoracic Society, European Respiratory Society.
    • American Thoracic Society, European Respiratory Society. ATS/ERS recommendations for standardized procedures for the online and offline measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide, 2005. Am. J. Respir. Crit. Care Med. 2005; 171: 912-930.
    • (2005) Am. J. Respir. Crit. Care Med. , vol.171 , pp. 912-930
  • 14
    • 80052755474 scopus 로고    scopus 로고
    • Management of asthma in pregnancy guided by measurement of fraction of exhaled nitric oxide: A double-blind, randomized controlled trial
    • Powell H, Murphy VE, Taylor DR, Hensley MJ, McCaffery K, Giles W, Clifton VL, Gibson PG,. Management of asthma in pregnancy guided by measurement of fraction of exhaled nitric oxide: a double-blind, randomized controlled trial. Lancet 2011; 378: 983-990.
    • (2011) Lancet , vol.378 , pp. 983-990
    • Powell, H.1    Murphy, V.E.2    Taylor, D.R.3    Hensley, M.J.4    McCaffery, K.5    Giles, W.6    Clifton, V.L.7    Gibson, P.G.8
  • 15
    • 74949090574 scopus 로고    scopus 로고
    • Tailored interventions based on exhaled nitric oxide versus clinical symptoms for asthma in children and adults
    • CD006340.
    • Petsky HL, Cates CJ, Li A, Kynaston JA, Turner C, Chang AB,. Tailored interventions based on exhaled nitric oxide versus clinical symptoms for asthma in children and adults. Cochrane Database Syst. Rev. 2009; (4): CD006340.
    • (2009) Cochrane Database Syst. Rev. , Issue.4
    • Petsky, H.L.1    Cates, C.J.2    Li, A.3    Kynaston, J.A.4    Turner, C.5    Chang, A.B.6
  • 18
    • 84883601416 scopus 로고    scopus 로고
    • Biomarkers in exhaled breath condensate: A review of collection, processing and analysis
    • Grob NM, Aytekin M, Dweik RA,. Biomarkers in exhaled breath condensate: a review of collection, processing and analysis. J. Breath. Res. 2008; 2: 037004.
    • (2008) J. Breath. Res. , vol.2 , pp. 037004
    • Grob, N.M.1    Aytekin, M.2    Dweik, R.A.3
  • 19
    • 33749582774 scopus 로고    scopus 로고
    • Exhaled breath condensate nitrite/nitrate and pH in relation to pediatric asthma control and exhaled nitric oxide
    • Ratnawati R, Morton J, Henry RL, Thomas PS,. Exhaled breath condensate nitrite/nitrate and pH in relation to pediatric asthma control and exhaled nitric oxide. Pediatr. Pulmonol. 2006; 41: 929-936.
    • (2006) Pediatr. Pulmonol. , vol.41 , pp. 929-936
    • Ratnawati, R.1    Morton, J.2    Henry, R.L.3    Thomas, P.S.4
  • 20
    • 35748955539 scopus 로고    scopus 로고
    • Exhaled breath condensate pH assays
    • Hunt J,. Exhaled breath condensate pH assays. Immunol. Allergy Clin. North Am. 2007; 27: 597-606.
    • (2007) Immunol. Allergy Clin. North Am. , vol.27 , pp. 597-606
    • Hunt, J.1
  • 21
    • 79960429164 scopus 로고    scopus 로고
    • Hydrogen peroxide in exhaled breath condensate in patients with asthma: A promising biomarker?
    • Teng Y, Sun P, Zhang J, Yu R, Bai J, Yao X, Huang M, Adcock IM, Barnes PJ,. Hydrogen peroxide in exhaled breath condensate in patients with asthma: a promising biomarker? Chest 2011; 140: 108-116.
    • (2011) Chest , vol.140 , pp. 108-116
    • Teng, Y.1    Sun, P.2    Zhang, J.3    Yu, R.4    Bai, J.5    Yao, X.6    Huang, M.7    Adcock, I.M.8    Barnes, P.J.9
  • 22
    • 84882911915 scopus 로고    scopus 로고
    • Differential expression of microRNAs in exhaled breath condensates of patients with asthma, patients with chronic obstructive pulmonary disease, and healthy adults
    • Pinkerton M, Chinchilli V, Banta E, Craig T, August A, Bascom R, Cantorna M, Harvill E, Ishmael FT,. Differential expression of microRNAs in exhaled breath condensates of patients with asthma, patients with chronic obstructive pulmonary disease, and healthy adults. J. Allergy Clin. Immunol. 2013; 132: 217-292.
    • (2013) J. Allergy Clin. Immunol. , vol.132 , pp. 217-292
    • Pinkerton, M.1    Chinchilli, V.2    Banta, E.3    Craig, T.4    August, A.5    Bascom, R.6    Cantorna, M.7    Harvill, E.8    Ishmael, F.T.9
  • 24
    • 33746727618 scopus 로고    scopus 로고
    • Effects of a leukotriene receptor antagonist on exhaled leukotriene E4 and prostanoids in children with asthma
    • Montuschi P, Mondino C, Koch P, Barnes PJ, Ciabattoni G,. Effects of a leukotriene receptor antagonist on exhaled leukotriene E4 and prostanoids in children with asthma. J. Allergy Clin. Immunol. 2006; 118: 347-353.
    • (2006) J. Allergy Clin. Immunol. , vol.118 , pp. 347-353
    • Montuschi, P.1    Mondino, C.2    Koch, P.3    Barnes, P.J.4    Ciabattoni, G.5
  • 26
    • 24744434955 scopus 로고    scopus 로고
    • Comparative measurement of thromboxane A2 metabolites in exhaled breath condensate by different immunoassays
    • Huszar E, Szabo Z, Jakab A, Barta I, Herjavecz I, Horvath I,. Comparative measurement of thromboxane A2 metabolites in exhaled breath condensate by different immunoassays. Inflamm. Res. 2005; 54: 350-355.
    • (2005) Inflamm. Res. , vol.54 , pp. 350-355
    • Huszar, E.1    Szabo, Z.2    Jakab, A.3    Barta, I.4    Herjavecz, I.5    Horvath, I.6
  • 27
    • 0036227909 scopus 로고    scopus 로고
    • Exhaled leukotrienes and prostaglandins in asthma
    • Montuschi P, Barnes PJ,. Exhaled leukotrienes and prostaglandins in asthma. J. Allergy Clin. Immunol. 2002; 109: 615-620.
    • (2002) J. Allergy Clin. Immunol. , vol.109 , pp. 615-620
    • Montuschi, P.1    Barnes, P.J.2
  • 28
    • 54449087661 scopus 로고    scopus 로고
    • Increased 8-isoprostane, a marker of oxidative stress in exhaled breath condensate in subjects with asbestos exposure
    • Pelclova D, Fenclova Z, Kacer P, Kuzma M, Navratil T, Lebedova J,. Increased 8-isoprostane, a marker of oxidative stress in exhaled breath condensate in subjects with asbestos exposure. Ind. Health 2008; 46: 484-489.
    • (2008) Ind. Health , vol.46 , pp. 484-489
    • Pelclova, D.1    Fenclova, Z.2    Kacer, P.3    Kuzma, M.4    Navratil, T.5    Lebedova, J.6
  • 30
    • 38449104335 scopus 로고    scopus 로고
    • Endothelin-1 in exhaled breath condensate of allergic asthma patients with exercise-induced bronchoconstriction
    • Zietkowski Z, Skiepko R, Tomasiak MM, Bodzenta-Lukaszyk A,. Endothelin-1 in exhaled breath condensate of allergic asthma patients with exercise-induced bronchoconstriction. Respir. Res. 2007; 8: 76.
    • (2007) Respir. Res. , vol.8 , pp. 76
    • Zietkowski, Z.1    Skiepko, R.2    Tomasiak, M.M.3    Bodzenta-Lukaszyk, A.4
  • 33
    • 84860387834 scopus 로고    scopus 로고
    • Exhaled breath condensate MMP-9 level and its relationship with asthma severity and interleukin-4/10 levels in children
    • Karakoc GB, Yukselen A, Yilmaz M, Altintas DU, Kendirli SG,. Exhaled breath condensate MMP-9 level and its relationship with asthma severity and interleukin-4/10 levels in children. Ann. Allergy Asthma Immunol. 2012; 108: 300-304.
    • (2012) Ann. Allergy Asthma Immunol. , vol.108 , pp. 300-304
    • Karakoc, G.B.1    Yukselen, A.2    Yilmaz, M.3    Altintas, D.U.4    Kendirli, S.G.5
  • 35
    • 78951493340 scopus 로고    scopus 로고
    • Exhaled breath temperature, a new biomarker in asthma control: A pilot study
    • Melo RE, Popov TA, Sole D,. Exhaled breath temperature, a new biomarker in asthma control: a pilot study. J. Bras. Pneumol. 2010; 36: 693-699.
    • (2010) J. Bras. Pneumol. , vol.36 , pp. 693-699
    • Melo, R.E.1    Popov, T.A.2    Sole, D.3
  • 36
    • 84879616779 scopus 로고    scopus 로고
    • When are biomarkers required in the management of airway diseases?
    • Dasgupta A, Nair P,. When are biomarkers required in the management of airway diseases? Pol. Arch. Med. Wewn. 2013; 123: 183-188.
    • (2013) Pol. Arch. Med. Wewn. , vol.123 , pp. 183-188
    • Dasgupta, A.1    Nair, P.2
  • 37
    • 0036785387 scopus 로고    scopus 로고
    • Sputum eosinophil count in a large population of patients with mild to moderate steroid-naive asthma: Distribution and relationship with methacholine bronchial hyperresponsiveness
    • Louis R, Sele J, Henket M, Cataldo D, Bettiol J, Seiden L, Bartsch P,. Sputum eosinophil count in a large population of patients with mild to moderate steroid-naive asthma: distribution and relationship with methacholine bronchial hyperresponsiveness. Allergy 2002; 57: 907-912.
    • (2002) Allergy , vol.57 , pp. 907-912
    • Louis, R.1    Sele, J.2    Henket, M.3    Cataldo, D.4    Bettiol, J.5    Seiden, L.6    Bartsch, P.7
  • 38
    • 0032787222 scopus 로고    scopus 로고
    • Lung function and sputum characteristics of patients with severe asthma during an induced exacerbation by double-blind steroid withdrawal
    • in't Veen JC, Smits HH, Hiemstra PS, Zwinderman AE, Sterk PJ, Bel EH,. Lung function and sputum characteristics of patients with severe asthma during an induced exacerbation by double-blind steroid withdrawal. Am. J. Respir. Crit. Care Med. 1999; 160: 93-99.
    • (1999) Am. J. Respir. Crit. Care Med. , vol.160 , pp. 93-99
    • In'T Veen, J.C.1    Smits, H.H.2    Hiemstra, P.S.3    Zwinderman, A.E.4    Sterk, P.J.5    Bel, E.H.6
  • 41
    • 33644696311 scopus 로고    scopus 로고
    • Cysteinyl-leukotrienes contribute to sputum eosinophil chemotactic activity in asthmatics
    • Hemelaers L, Henket M, Sele J, Bureau F, Louis R,. Cysteinyl-leukotrienes contribute to sputum eosinophil chemotactic activity in asthmatics. Allergy 2006; 61: 136-139.
    • (2006) Allergy , vol.61 , pp. 136-139
    • Hemelaers, L.1    Henket, M.2    Sele, J.3    Bureau, F.4    Louis, R.5
  • 42
    • 48449103440 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-1 (PAI-1) and urokinase plasminogen activator (uPA) in sputum of allergic asthma patients
    • Kowal K, Zukowski S, Moniuszko M, Bodzenta-Lukaszyk A,. Plasminogen activator inhibitor-1 (PAI-1) and urokinase plasminogen activator (uPA) in sputum of allergic asthma patients. Folia Histochem. Cytobiol. 2008; 46: 193-198.
    • (2008) Folia Histochem. Cytobiol. , vol.46 , pp. 193-198
    • Kowal, K.1    Zukowski, S.2    Moniuszko, M.3    Bodzenta-Lukaszyk, A.4
  • 43
    • 49249105776 scopus 로고    scopus 로고
    • Sputum neurokinin A in Egyptian asthmatic children and adolescents: Relation to exacerbation severity
    • Mostafa GA, Reda SM, Abd El-Aziz MM, Ahmed SA,. Sputum neurokinin A in Egyptian asthmatic children and adolescents: relation to exacerbation severity. Allergy 2008; 63: 1244-1247.
    • (2008) Allergy , vol.63 , pp. 1244-1247
    • Mostafa, G.A.1    Reda, S.M.2    Abd El-Aziz, M.M.3    Ahmed, S.A.4
  • 44
    • 34247589697 scopus 로고    scopus 로고
    • An investigation of airway acidification in asthma using induced sputum: A study of feasibility and correlation
    • Kodric M, Shah AN, Fabbri LM, Confalonieri M,. An investigation of airway acidification in asthma using induced sputum: a study of feasibility and correlation. Am. J. Respir. Crit. Care Med. 2007; 175: 905-910.
    • (2007) Am. J. Respir. Crit. Care Med. , vol.175 , pp. 905-910
    • Kodric, M.1    Shah, A.N.2    Fabbri, L.M.3    Confalonieri, M.4
  • 46
    • 0036435871 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9 expression in asthma: Effect of asthma severity, allergen challenge, and inhaled corticosteroids
    • Mattos W, Lim S, Russell R, Jatakanon A, Chung KF, Barnes PJ,. Matrix metalloproteinase-9 expression in asthma: effect of asthma severity, allergen challenge, and inhaled corticosteroids. Chest 2002; 122: 1543-1552.
    • (2002) Chest , vol.122 , pp. 1543-1552
    • Mattos, W.1    Lim, S.2    Russell, R.3    Jatakanon, A.4    Chung, K.F.5    Barnes, P.J.6
  • 49
    • 80051491390 scopus 로고    scopus 로고
    • Montelukast for the treatment of asthma in the adult population
    • Amlani S, Nadarajah T, McIvor RA,. Montelukast for the treatment of asthma in the adult population. Expert Opin. Pharmacother. 2011; 12: 2119-2128.
    • (2011) Expert Opin. Pharmacother. , vol.12 , pp. 2119-2128
    • Amlani, S.1    Nadarajah, T.2    McIvor, R.A.3
  • 50
    • 80052267387 scopus 로고    scopus 로고
    • What effect does asthma treatment have on airway remodeling? Current perspectives
    • quiz 49-50.
    • Durrani SR, Viswanathan RK, Busse WW,. What effect does asthma treatment have on airway remodeling? Current perspectives. J. Allergy Clin. Immunol. 2011; 128: 439-448; quiz 49-50.
    • (2011) J. Allergy Clin. Immunol. , vol.128 , pp. 439-448
    • Durrani, S.R.1    Viswanathan, R.K.2    Busse, W.W.3
  • 53
    • 77953867912 scopus 로고    scopus 로고
    • Eosinophil-derived neurotoxin in childhood asthma: Correlation with disease severity
    • Kim CK, Callaway Z, Fletcher R, Koh YY,. Eosinophil-derived neurotoxin in childhood asthma: correlation with disease severity. J. Asthma 2010; 47: 568-573.
    • (2010) J. Asthma , vol.47 , pp. 568-573
    • Kim, C.K.1    Callaway, Z.2    Fletcher, R.3    Koh, Y.Y.4
  • 57
    • 84455181468 scopus 로고    scopus 로고
    • C3 and C4 complement system components as biomarkers in the intermittent atopic asthma diagnosis
    • Mosca T, Menezes MC, Dionigi PC, Stirbulov R, Forte WC,. C3 and C4 complement system components as biomarkers in the intermittent atopic asthma diagnosis. J. Pediatr. (Rio J.) 2011; 87: 512-516.
    • (2011) J. Pediatr. (Rio J.) , vol.87 , pp. 512-516
    • Mosca, T.1    Menezes, M.C.2    Dionigi, P.C.3    Stirbulov, R.4    Forte, W.C.5
  • 58
    • 79952192380 scopus 로고    scopus 로고
    • Detection of immunological biomarkers correlated with asthma control and quality of life measurements in sera from chronic asthmatic patients
    • Patil SP, Wisnivesky JP, Busse PJ, Halm EA, Li XM,. Detection of immunological biomarkers correlated with asthma control and quality of life measurements in sera from chronic asthmatic patients. Ann. Allergy Asthma Immunol. 2011; 106: 205-213.
    • (2011) Ann. Allergy Asthma Immunol. , vol.106 , pp. 205-213
    • Patil, S.P.1    Wisnivesky, J.P.2    Busse, P.J.3    Halm, E.A.4    Li, X.M.5
  • 60
  • 61
    • 84859225639 scopus 로고    scopus 로고
    • Serum chemokines RANTES and monocyte chemo attractant protein-1 in Egyptian patients with atopic asthma: Relationship to disease severity
    • Saad-El-Din Bessa S, Abo El-Magd GH, Mabrouk MM,. Serum chemokines RANTES and monocyte chemo attractant protein-1 in Egyptian patients with atopic asthma: relationship to disease severity. Arch. Med. Res. 2012; 43: 36-41.
    • (2012) Arch. Med. Res. , vol.43 , pp. 36-41
    • Saad-El-Din Bessa, S.1    Abo El-Magd, G.H.2    Mabrouk, M.M.3
  • 64
    • 77951194004 scopus 로고    scopus 로고
    • YKL-40 in asthmatic patients, and its correlations with exacerbation, eosinophils and immunoglobulin e
    • Tang H, Fang Z, Sun Y, Li B, Shi Z, Chen J, Zhang T, Xiu Q,. YKL-40 in asthmatic patients, and its correlations with exacerbation, eosinophils and immunoglobulin E. Eur. Respir. J. 2010; 35: 757-760.
    • (2010) Eur. Respir. J. , vol.35 , pp. 757-760
    • Tang, H.1    Fang, Z.2    Sun, Y.3    Li, B.4    Shi, Z.5    Chen, J.6    Zhang, T.7    Xiu, Q.8
  • 65
    • 80053285311 scopus 로고    scopus 로고
    • YKL-40 protein is a marker of asthma
    • Specjalski K, Jassem E,. YKL-40 protein is a marker of asthma. J. Asthma 2011; 48: 767-772.
    • (2011) J. Asthma , vol.48 , pp. 767-772
    • Specjalski, K.1    Jassem, E.2
  • 66
    • 79960715523 scopus 로고    scopus 로고
    • Serum OX40 ligand levels in asthmatic children: A potential biomarker of severity and persistence
    • Ezzat MH, Imam SS, Shaheen KY, Elbrhami EM,. Serum OX40 ligand levels in asthmatic children: a potential biomarker of severity and persistence. Allergy Asthma Proc. 2011; 32: 313-318.
    • (2011) Allergy Asthma Proc. , vol.32 , pp. 313-318
    • Ezzat, M.H.1    Imam, S.S.2    Shaheen, K.Y.3    Elbrhami, E.M.4
  • 68
    • 0029792615 scopus 로고    scopus 로고
    • The leukotrienes: Mediators of chronic inflammation in asthma
    • Sampson AP,. The leukotrienes: mediators of chronic inflammation in asthma. Clin. Exp. Allergy 1996; 26: 995-1004.
    • (1996) Clin. Exp. Allergy , vol.26 , pp. 995-1004
    • Sampson, A.P.1
  • 69
    • 0033772785 scopus 로고    scopus 로고
    • Urinary excretion of leukotriene E4 and eosinophil protein X in children with atopic asthma
    • Severien C, Artlich A, Jonas S, Becher G,. Urinary excretion of leukotriene E4 and eosinophil protein X in children with atopic asthma. Eur. Respir. J. 2000; 16: 588-592.
    • (2000) Eur. Respir. J. , vol.16 , pp. 588-592
    • Severien, C.1    Artlich, A.2    Jonas, S.3    Becher, G.4
  • 72
    • 0027173832 scopus 로고
    • Differential effects of fluticasone propionate on allergen-evoked bronchoconstriction and increased urinary leukotriene E4 excretion
    • Shaughnessy KMO, Wellings R, Gillies B, Fuller RW,. Differential effects of fluticasone propionate on allergen-evoked bronchoconstriction and increased urinary leukotriene E4 excretion. Am. Rev. Respir. Dis. 1993; 147: 1472-1476.
    • (1993) Am. Rev. Respir. Dis. , vol.147 , pp. 1472-1476
    • Shaughnessy, K.M.O.1    Wellings, R.2    Gillies, B.3    Fuller, R.W.4
  • 73
    • 0029853741 scopus 로고    scopus 로고
    • Acute and chronic effects of a 5-lipoxygenase inhibitor in asthma: A 6-month randomized multicenter trial. Zileuton Study Group
    • Liu MC, Dube LM, Lancaster J,. Acute and chronic effects of a 5-lipoxygenase inhibitor in asthma: a 6-month randomized multicenter trial. Zileuton Study Group. J. Allergy Clin. Immunol. 1996; 98: 859-871.
    • (1996) J. Allergy Clin. Immunol. , vol.98 , pp. 859-871
    • Liu, M.C.1    Dube, L.M.2    Lancaster, J.3
  • 74
    • 84873343219 scopus 로고    scopus 로고
    • Urinary eosinophil protein X in childhood asthma: Relation with changes in disease control and eosinophilic airway inflammation
    • Nuijsink M, Hop WC, Sterk PJ, Duiverman EJ, De Jongste JC,. Urinary eosinophil protein X in childhood asthma: relation with changes in disease control and eosinophilic airway inflammation. Mediators Inflamm. 2013; 2013: 532619.
    • (2013) Mediators Inflamm. , vol.2013 , pp. 532619
    • Nuijsink, M.1    Hop, W.C.2    Sterk, P.J.3    Duiverman, E.J.4    De Jongste, J.C.5
  • 75
    • 0029792693 scopus 로고    scopus 로고
    • Increased urinary excretion of the prostaglandin D2 metabolite 9 alpha, 11 beta-prostaglandin F2 after aspirin challenge supports mast cell activation in aspirin-induced airway obstruction
    • O'Sullivan S, Dahlen B, Dahlen SE, Kumlin M,. Increased urinary excretion of the prostaglandin D2 metabolite 9 alpha, 11 beta-prostaglandin F2 after aspirin challenge supports mast cell activation in aspirin-induced airway obstruction. J. Allergy Clin. Immunol. 1996; 98: 421-432.
    • (1996) J. Allergy Clin. Immunol. , vol.98 , pp. 421-432
    • O'Sullivan, S.1    Dahlen, B.2    Dahlen, S.E.3    Kumlin, M.4
  • 77
    • 2042476057 scopus 로고    scopus 로고
    • Urinary leukotriene E4 and 9 alpha, 11 beta-prostaglandin F concentrations in mild, moderate and severe asthma, and in healthy subjects
    • Misso NL, Aggarwal S, Phelps S, Beard R, Thompson PJ,. Urinary leukotriene E4 and 9 alpha, 11 beta-prostaglandin F concentrations in mild, moderate and severe asthma, and in healthy subjects. Clin. Exp. Allergy 2004; 34: 624-631.
    • (2004) Clin. Exp. Allergy , vol.34 , pp. 624-631
    • Misso, N.L.1    Aggarwal, S.2    Phelps, S.3    Beard, R.4    Thompson, P.J.5
  • 78
    • 0033596905 scopus 로고    scopus 로고
    • 3-Bromotyrosine and 3, 5-dibromotyrosine are major products of protein oxidation by eosinophil peroxidase: Potential markers for eosinophil-dependent tissue injury in vivo
    • Wu W, Chen Y, d'Avignon A, Hazen SL,. 3-Bromotyrosine and 3, 5-dibromotyrosine are major products of protein oxidation by eosinophil peroxidase: potential markers for eosinophil-dependent tissue injury in vivo. Biochemistry 1999; 38: 3538-3548.
    • (1999) Biochemistry , vol.38 , pp. 3538-3548
    • Wu, W.1    Chen, Y.2    D'Avignon, A.3    Hazen, S.L.4
  • 80
    • 79961127439 scopus 로고    scopus 로고
    • Can anti-IgE therapy prevent airway remodeling in allergic asthma?
    • Rabe KF, Calhoun WJ, Smith N, Jimenez P,. Can anti-IgE therapy prevent airway remodeling in allergic asthma? Allergy 2011; 66: 1142-1151.
    • (2011) Allergy , vol.66 , pp. 1142-1151
    • Rabe, K.F.1    Calhoun, W.J.2    Smith, N.3    Jimenez, P.4
  • 81
    • 78649331032 scopus 로고    scopus 로고
    • Anti-IgE therapy with omalizumab decreases endothelin-1 in exhaled breath condensate of patients with severe persistent allergic asthma
    • Zietkowski Z, Skiepko R, Tomasiak-Lozowska MM, Bodzenta-Lukaszyk A,. Anti-IgE therapy with omalizumab decreases endothelin-1 in exhaled breath condensate of patients with severe persistent allergic asthma. Respiration 2010; 80: 534-542.
    • (2010) Respiration , vol.80 , pp. 534-542
    • Zietkowski, Z.1    Skiepko, R.2    Tomasiak-Lozowska, M.M.3    Bodzenta-Lukaszyk, A.4
  • 82
    • 33644746141 scopus 로고    scopus 로고
    • Role of anti-IgE monoclonal antibody (omalizumab) in the treatment of bronchial asthma and allergic respiratory diseases
    • D'Amato G,. Role of anti-IgE monoclonal antibody (omalizumab) in the treatment of bronchial asthma and allergic respiratory diseases. Eur. J. Pharmacol. 2006; 533: 302-307.
    • (2006) Eur. J. Pharmacol. , vol.533 , pp. 302-307
    • D'Amato, G.1
  • 85
    • 84865145614 scopus 로고    scopus 로고
    • Mepolizumab for severe eosinophilic asthma (DREAM): A multicenter, double-blind, placebo-controlled trial
    • Pavord ID, Korn S, Howarth P, Bleecker ER, Buhl R, Keene ON, Ortega H, Chanez P,. Mepolizumab for severe eosinophilic asthma (DREAM): a multicenter, double-blind, placebo-controlled trial. Lancet 2012; 380: 651-659.
    • (2012) Lancet , vol.380 , pp. 651-659
    • Pavord, I.D.1    Korn, S.2    Howarth, P.3    Bleecker, E.R.4    Buhl, R.5    Keene, O.N.6    Ortega, H.7    Chanez, P.8
  • 86
    • 84855487820 scopus 로고    scopus 로고
    • Recent advances in mechanisms and treatments of airway remodeling in asthma: A message from the bench side to the clinic
    • Cho JY,. Recent advances in mechanisms and treatments of airway remodeling in asthma: a message from the bench side to the clinic. Korean J. Intern. Med. 2011; 26: 367-383.
    • (2011) Korean J. Intern. Med. , vol.26 , pp. 367-383
    • Cho, J.Y.1
  • 87
    • 84860698476 scopus 로고    scopus 로고
    • Therapies for allergic inflammation: Refining strategies to induce tolerance
    • Akdis CA,. Therapies for allergic inflammation: refining strategies to induce tolerance. Nat. Med. 2012; 18: 736-749.
    • (2012) Nat. Med. , vol.18 , pp. 736-749
    • Akdis, C.A.1
  • 88
    • 45549122275 scopus 로고    scopus 로고
    • IL-13 as a therapeutic target for respiratory disease
    • Kasaian MT, Miller DK,. IL-13 as a therapeutic target for respiratory disease. Biochem. Pharmacol. 2008; 76: 147-155.
    • (2008) Biochem. Pharmacol. , vol.76 , pp. 147-155
    • Kasaian, M.T.1    Miller, D.K.2
  • 89
    • 84866756648 scopus 로고    scopus 로고
    • Lebrikizumab in the personalized management of asthma
    • Thomson NC, Patel M, Smith AD,. Lebrikizumab in the personalized management of asthma. Biologics. 2012; 6: 329-335.
    • (2012) Biologics. , vol.6 , pp. 329-335
    • Thomson, N.C.1    Patel, M.2    Smith, A.D.3
  • 90
    • 76749141384 scopus 로고    scopus 로고
    • A phase 1 study evaluating the pharmacokinetics, safety and tolerability of repeat dosing with a human IL-13 antibody (CAT-354) in subjects with asthma
    • Singh D, Kane B, Molfino NA, Faggioni R, Roskos L, Woodcock A,. A phase 1 study evaluating the pharmacokinetics, safety and tolerability of repeat dosing with a human IL-13 antibody (CAT-354) in subjects with asthma. BMC Pulm. Med. 2010; 10: 3.
    • (2010) BMC Pulm. Med. , vol.10 , pp. 3
    • Singh, D.1    Kane, B.2    Molfino, N.A.3    Faggioni, R.4    Roskos, L.5    Woodcock, A.6
  • 93
    • 7044264854 scopus 로고    scopus 로고
    • A comprehensive review and evaluation of the side effects of the tumor necrosis factor alpha blockers etanercept, infliximab and adalimumab
    • Scheinfeld N,. A comprehensive review and evaluation of the side effects of the tumor necrosis factor alpha blockers etanercept, infliximab and adalimumab. J. Dermatol. Treat. 2004; 15: 280-294.
    • (2004) J. Dermatol. Treat. , vol.15 , pp. 280-294
    • Scheinfeld, N.1
  • 94
    • 84875655178 scopus 로고    scopus 로고
    • Development of primary malignant melanoma during treatment with a TNF-alpha antagonist for severe Crohn's disease: A case report and review of the hypothetical association between TNF-alpha blockers and cancer
    • Kouklakis G, Efremidou EI, Pitiakoudis M, Liratzopoulos N, Polychronidis A,. Development of primary malignant melanoma during treatment with a TNF-alpha antagonist for severe Crohn's disease: a case report and review of the hypothetical association between TNF-alpha blockers and cancer. Drug Des. Dev. Ther. 2013; 7: 195-199.
    • (2013) Drug Des. Dev. Ther. , vol.7 , pp. 195-199
    • Kouklakis, G.1    Efremidou, E.I.2    Pitiakoudis, M.3    Liratzopoulos, N.4    Polychronidis, A.5
  • 96
    • 80053644690 scopus 로고    scopus 로고
    • Targeting eosinophil biology in asthma therapy
    • Wegmann M,. Targeting eosinophil biology in asthma therapy. Am. J. Respir. Cell Mol. Biol. 2011; 45: 667-674.
    • (2011) Am. J. Respir. Cell Mol. Biol. , vol.45 , pp. 667-674
    • Wegmann, M.1
  • 98
  • 99
    • 67649207586 scopus 로고    scopus 로고
    • Anti-IL-33 antibody treatment inhibits airway inflammation in a murine model of allergic asthma
    • Liu X, Li M, Wu Y, Zhou Y, Zeng L, Huang T,. Anti-IL-33 antibody treatment inhibits airway inflammation in a murine model of allergic asthma. Biochem. Biophys. Res. Commun. 2009; 386: 181-185.
    • (2009) Biochem. Biophys. Res. Commun. , vol.386 , pp. 181-185
    • Liu, X.1    Li, M.2    Wu, Y.3    Zhou, Y.4    Zeng, L.5    Huang, T.6
  • 100
    • 84861054351 scopus 로고    scopus 로고
    • IL-17A and IL-25: Therapeutic targets for allergic and exacerbated asthmatic disease
    • Petersen BC, Lukacs NW,. IL-17A and IL-25: therapeutic targets for allergic and exacerbated asthmatic disease. Future. Med. Chem. 2012; 4: 833-836.
    • (2012) Future. Med. Chem. , vol.4 , pp. 833-836
    • Petersen, B.C.1    Lukacs, N.W.2
  • 101
    • 84874861697 scopus 로고    scopus 로고
    • Exhaled nitric oxide as biomarker of acute lung injury: An unfulfilled promise?
    • Boshier PR, Hanna GB, Marczin N,. Exhaled nitric oxide as biomarker of acute lung injury: an unfulfilled promise? J. Breath. Res. 2013; 7: 017118.
    • (2013) J. Breath. Res. , vol.7 , pp. 017118
    • Boshier, P.R.1    Hanna, G.B.2    Marczin, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.