Hydrogen peroxide in exhaled breath condensate in patients with asthma: A promising biomarker?

Chest

Volumn 140, Issue 1, 2011, Pages 108-116

  Teng, Yue ^a   Sun, Peili ^a   Zhang, Jingying ^a   Yu, Rongbin ^a   Bai, Jianling ^a   Yao, Xin ^a   Huang, Mao ^a   Adcock, Ian M ^b   Barnes, Peter J ^b  

^a NANJING MEDICAL UNIVERSITY   (China)

^b NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID; HYDROGEN PEROXIDE;

ARTICLE; ASTHMA; COMPUTER PROGRAM; DISEASE CLASSIFICATION; DISEASE CONTROL; DISEASE SEVERITY; EXHALED BREATH CONDENSATE; FORCED EXPIRATORY VOLUME; HUMAN; OBSERVATIONAL STUDY; PRIORITY JOURNAL; RESPIRATORY TRACT PARAMETERS; SYSTEMATIC REVIEW;

EID: 79960429164     PISSN: 00123692     EISSN: 19313543     Source Type: Journal    
DOI: 10.1378/chest.10-2816     Document Type: Article

References (54)

1. Tattersfield AE, Knox AJ, Britton JR, Hall IP. Asthma. Lancet. 2002;360(9342):1313-1322. (Pubitemid 35284626)
2. Busse WW, Lemanske RF Jr. Asthma. N Engl J Med. 2001; 344(5):350-362. (Pubitemid 32107645)
3. Louis R, Lau LC, Bron AO, Roldaan AC, Radermecker M, Djukanović R. The relationship between airways inflammation and asthma severity. Am J Respir Crit Care Med. 2000; 161(1):9-16. (Pubitemid 30055896)
4. Jatakanon A, Lim S, Barnes PJ. Changes in sputum eosinophils predict loss of asthma control. Am J Respir Crit Care Med. 2000;161(1):64-72. (Pubitemid 30055904)
5. Kharitonov SA, Yates D, Robbins RA, Logan-Sinclair R, Shinebourne EA, Barnes PJ. Increased nitric oxide in exhaled air of asthmatic patients. Lancet. 1994;343(8890):133-135. (Pubitemid 24028638)
6. Malerba M, Ragnoli B, Radaeli A, Tantucci C. Usefulness of exhaled nitric oxide and sputum eosinophils in the longterm control of eosinophilic asthma. Chest. 2008;134(4):733-739.
7. Montuschi P, Mondino C, Koch P, Ciabattoni G, Barnes PJ, Baviera G. Effects of montelukast treatment and withdrawal on fractional exhaled nitric oxide and lung function in children with asthma. Chest. 2007;132(6):1876-1881.
8. Zhang J, Yao X, Yu R, et al. Exhaled carbon monoxide in asthmatics: a meta-analysis. Respir Res. 2010;11:50.
9. Montuschi P, Santonico M, Mondino C, et al. Diagnostic performance of an electronic nose, fractional exhaled nitric oxide, and lung function testing in asthma. Chest. 2010;137(4):790-796.
10. Petsky HL, Cates CJ, Li A, Kynaston JA, Turner C, Chang AB. Tailored interventions based on exhaled nitric oxide versus clinical symptoms for asthma in children and adults. Cochrane Database Syst Rev. 2009;(4):CD006340.
11. Rahman I, Morrison D, Donaldson K, MacNee W. Systemic oxidative stress in asthma, COPD, and smokers. Am J Respir Crit Care Med. 1996;154(4 Pt 1):1055-1060.
12. Sugiura H, Ichinose M. Oxidative and nitrative stress in bronchial asthma. Antioxid Redox Signal. 2008;10(4):785-797. (Pubitemid 351225897)
13. Comhair SA, Erzurum SC. Redox control of asthma: molecular mechanisms and therapeutic opportunities [published correction appears in Antioxid Redox Signal. 2010;12(2):321]. Antioxid Redox Signal. 2010;12(1):93-124.
14. Dohlman AW, Black HR, Royall JA. Expired breath hydrogen peroxide is a marker of acute airway inflammation in pediatric patients with asthma. Am Rev Respir Dis. 1993;148(4 Pt 1):955-960. (Pubitemid 23301213)
15. Montuschi P. Analysis of exhaled breath condensate in respiratory medicine: methodological aspects and potential clinical applications. Ther Adv Respir Dis. 2007;1(1):5-23.
16. Carpenter CT, Price PV, Christman BW. Exhaled breath condensate isoprostanes are elevated in patients with acute lung injury or ARDS. Chest. 1998;114(6):1653-1659. (Pubitemid 128487489)
17. Montuschi P, Ragazzoni E, Valente S, et al. Validation of 8-isoprostane and prostaglandin E(2) measurements in exhaled breath condensate. Inflamm Res. 2003;52(12):502-507. (Pubitemid 38058224)
18. Montuschi P, Ragazzoni E, Valente S, et al. Validation of leukotriene B4 measurements in exhaled breath condensate. Inflamm Res. 2003;52(2):69-73. (Pubitemid 36286704)
19. Montuschi P, Martello S, Felli M, Mondino C, Barnes PJ, Chiarotti M. Liquid chromatography/mass spectrometry analysis of exhaled leukotriene B4 in asthmatic children. Respir Res. 2005;6 :119.
20. Montuschi P, Martello S, Felli M, Mondino C, Chiarotti M. Ion trap liquid chromatography/tandem mass spectrometry analysis of leukotriene B4 in exhaled breath condensate. Rapid Commun Mass Spectrom. 2004;18(22):2723-2729. (Pubitemid 39546004)
21. Montuschi P. LC/MS/MS analysis of leukotriene B4 and other eicosanoids in exhaled breath condensate for assessing lung inflammation. J Chromatogr B Analyt Technol Biomed Life Sci. 2009;877(13):1272-1280.
22. Horváth I, Donnelly LE, Kiss A, et al. Combined use of exhaled hydrogen peroxide and nitric oxide in monitoring asthma. Am J Respir Crit Care Med. 1998;158(4):1042-1046. (Pubitemid 28488999)
23. Antczak A, Nowak D, Shariati B, Król M, Piasecka G, Kurmanowska Z. Increased hydrogen peroxide and thiobarbituric acid-reactive products in expired breath condensate of asthmatic patients. Eur Respir J. 1997;10(6):1235-1241. (Pubitemid 27278239)
24. Robroeks CM, van de Kant KD, Jöbsis Q, et al. Exhaled nitric oxide and biomarkers in exhaled breath condensate indicate the presence, severity and control of childhood asthma. Clin Exp Allergy. 2007;37(9):1303-1311. (Pubitemid 47372295)
25. Fireman E, Shtark M, Priel IE, et al. Hydrogen peroxide in exhaled breath condensate(EBC) vs eosinophil count in induced sputum(IS) in parenchymal vs airways lung diseases. Inflammation. 2007;30(1-2):44-51. (Pubitemid 46438047)
26. Kietzmann D, Kahl R, Müller M, Burchardi H, Kettler D. Hydrogen peroxide in expired breath condensate of patients with acute respiratory failure and with ARDS. Intensive Care Med. 1993;19(2):78-81. (Pubitemid 23114204)
27. Baldwin SR, Simon RH, Grum CM, Ketai LH, Boxer LA, Devall LJ. Oxidant activity in expired breath of patients with adult respiratory distress syndrome. Lancet. 1986;1(8471):11-14.
28. Sznajder JI, Fraiman A, Hall JB, et al. Increased hydrogen peroxide in the expired breath of patients with acute hypoxemic respiratory failure. Chest. 1989;96(3):606-612. (Pubitemid 19230385)
29. Al Obaidi AH, Al Samarai AM. Biochemical markers as a response guide for steroid therapy in asthma. J Asthma. 2008; 45(5):425-428. (Pubitemid 351882724)
30. Robroeks CM, van de Kant KD, van Vliet D, et al. Comparison of the anti-inflammatory effects of extra-fine hydrofluoroalkanebeclomethasone vs fluticasone dry powder inhaler on exhaled inflammatory markers in childhood asthma. Ann Allergy Asthma Immunol. 2008;100(6):601-607. (Pubitemid 351829861)
31. Antczak A, Nowak D, Bialasiewicz P, Kasielski M. Hydrogen peroxide in expired air condensate correlates positively with early steps of peripheral neutrophil activation in asthmatic patients. Arch Immunol Ther Exp(Warsz). 1999;47(2):119-126.
32. Svensson S, Olin AC, Lärstad M, Ljungkvist G, Torén K. Determination of hydrogen peroxide in exhaled breath condensate by flow injection analysis with fluorescence detection. J Chromatogr B Analyt Technol Biomed Life Sci. 2004; 809(2):199-203. (Pubitemid 39094694)
33. Horváth I, Donnelly LE, Kiss A, Balint B, Kharitonov SA, Barnes PJ. Exhaled nitric oxide and hydrogen peroxide concentrations in asthmatic smokers. Respiration. 2004;71(5):463-468. (Pubitemid 39370466)
34. Emelyanov A, Fedoseev G, Abulimity A, et al. Elevated concentrations of exhaled hydrogen peroxide in asthmatic patients. Chest. 2001;120(4):1136-1139. (Pubitemid 32960083)
35. Loukides S, Bouros D, Papatheodorou G, Panagou P, Siafakas NM. The relationships among hydrogen peroxide in expired breath condensate, airway inflammation, and asthma severity. Chest. 2002;121(2):338-346. (Pubitemid 34132967)
36. Al-Obaidy AH, Al-Samarai AG. Exhaled breath condensate pH and hydrogen peroxide as non-invasive markers for asthma. Saudi Med J. 2007;28(12):1860-1863. (Pubitemid 351863920)
37. Al Obaidi AH. Expired breath condensate hydrogen peroxide concentration and pH for screening cough variant asthma among chronic cough. Ann Thorac Med. 2007;2(1):18-22.
38. Ueno T, Kataoka M, Hirano A, et al. Inflammatory markers in exhaled breath condensate from patients with asthma. Respirology. 2008;13(5):654-663. (Pubitemid 351977587)
39. Begg CB, Mazumdar M. Operating characteristics of a rank correlation test for publication bias. Biometrics. 1994;50(4): 1088-1101.
40. Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ. 1997;315(7109):629-634. (Pubitemid 27387172)
41. Global Initiative for Asthma. GINA report, global strategy for asthma management and prevention. Global Initiative for Asthma Web site. www.ginasthma.com. Updated December 2010. Accessed April 28, 2011.
42. Fisher R. Statistical Methods for Research Workers. Newdelhi, India; Genesis Publishing Pvt Ltd; 2006.
43. Rahman I, Yang SR, Biswas SK. Current concepts of redox signaling in the lungs. Antioxid Redox Signal. 2006;8(3-4):681-689. (Pubitemid 43741336)
44. Jöbsis Q, Raatgeep HC, Schellekens SL, Hop WC, Hermans PW, de Jongste JC. Hydrogen peroxide in exhaled air of healthy children: Reference values. Eur Respir J. 1998;12(2):483-485. (Pubitemid 28389550)
45. Moffatt MF, Gut IG, Demenais F, et al; GABRIEL Consortium. A large-scale, consortium-based genomewide association study of asthma. N Engl J Med. 2010;363(13):1211-1221.
46. Schleiss MB, Holz O, Behnke M, Richter K, Magnussen H, Jörres RA. The concentration of hydrogen peroxide in exhaled air depends on expiratory flow rate. Eur Respir J. 2000;16(6): 1115-1118. (Pubitemid 32148127)
47. Kostikas K, Papatheodorou G, Psathakis K, Panagou P, Loukides S. Oxidative stress in expired breath condensate of patients with COPD. Chest. 2003;124(4):1373-1380. (Pubitemid 37290047)
48. Ho LP, Faccenda J, Innes JA, Greening AP. Expired hydrogen peroxide in breath condensate of cystic fibrosis patients. Eur Respir J. 1999;13(1):103-106. (Pubitemid 29079228)
49. van Beurden WJ, Dekhuijzen PN, Harff GA, Smeenk FW. Variability of exhaled hydrogen peroxide in stable COPD patients and matched healthy controls. Respiration. 2002; 69(3):211-216. (Pubitemid 34827834)
50. Nakayama T, Church DF, Pryor WA. Quantitative analysis of the hydrogen peroxide formed in aqueous cigarette tar extracts. Free Radic Biol Med. 1989;7(1):9-15. (Pubitemid 19165149)
51. Barreto M, Villa MP, Corradi M, et al. Non-invasive assessment of airway inflammation in ship-engine workers. Int J Immunopathol Pharmacol. 2006;19(3):601-608. (Pubitemid 44580533)
52. Guatura SB, Martinez JA, Santos Bueno PC, Santos ML. Increased exhalation of hydrogen peroxide in healthy subjects following cigarette consumption. Sao Paulo Med J. 2000;118(4):93-98.
53. Nowak D, Antczak A, Krol M, et al. Increased content of hydrogen peroxide in the expired breath of cigarette smokers. Eur Respir J. 1996;9(4):652-657. (Pubitemid 26167866)
54. Zappacosta B, Persichilli S, Mormile F, et al. A fast chemiluminescent method for H(2)O(2) measurement in exhaled breath condensate. Clin Chim Acta. 2001;310(2):187-191. (Pubitemid 32728348)