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Volumn 12, Issue 13, 2011, Pages 2119-2128

Montelukast for the treatment of asthma in the adult population

Author keywords

asthma; leukotriene receptor antagonists; montelukast

Indexed keywords

BECLOMETASONE; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; BRONCHODILATING AGENT; BUDESONIDE; CHOLINERGIC RECEPTOR BLOCKING AGENT; CORTICOSTEROID; DIGOXIN; FLUTICASONE; IMMUNOGLOBULIN E ANTIBODY; LEUKOTRIENE RECEPTOR BLOCKING AGENT; MONTELUKAST; PHENYTOIN; PLACEBO; SALMETEROL; STEROID; THEOPHYLLINE; WARFARIN; ZAFIRLUKAST;

EID: 80051491390     PISSN: 14656566     EISSN: 17447666     Source Type: Journal    
DOI: 10.1517/14656566.2011.600689     Document Type: Review
Times cited : (41)

References (65)
  • 1
    • 0025164256 scopus 로고
    • Leukotrienes and other products of the 5-lipoxygenase pathway. Biochemistry and relation to pathobiology in human diseases
    • Lewis RA, Austen KF, Soberman RJ. Leukotrienes and other products of the 5-lipoxygenase pathway. Biochemistry and relation to pathobiology in human diseases. N Engl J Med 1990;323:645-55 (Pubitemid 20280195)
    • (1990) New England Journal of Medicine , vol.323 , Issue.10 , pp. 645-655
    • Lewis, R.A.1    Austen, K.F.2    Soberman, R.J.3
  • 2
    • 0030664979 scopus 로고    scopus 로고
    • Choosing therapy for childhood asthma
    • DOI 10.1056/NEJM199712043372312
    • Holgate ST, Frew AJ. Choosing therapy for childhood asthma. N Engl J Med 1997;337:1690-2 (Pubitemid 27510111)
    • (1997) New England Journal of Medicine , vol.337 , Issue.23 , pp. 1690-1692
    • Holgate, S.T.1    Frew, A.J.2
  • 3
    • 77951654789 scopus 로고    scopus 로고
    • Canadian thoracic society asthma continuum- 2010 consensus summary for children six years of age and over, and adults
    • Lougheed DM, Lemiere C, Dell SD, et al. Canadian Thoracic Society Asthma Continuum - 2010 consensus summary for children six years of age and over, and adults. Can Respir J 2010;17:15-24
    • (2010) Can Respir J , vol.17 , pp. 15-24
    • Lougheed, D.M.1    Lemiere, C.2    Dell, S.D.3
  • 5
    • 79952177972 scopus 로고    scopus 로고
    • Montelukast: Pharmacology, safety, tolerability and efficacy
    • Benninger MS, Waters H. Montelukast: Pharmacology, safety, tolerability and efficacy. Clin Med Ther 2009;1:1253-61
    • (2009) Clin Med Ther , vol.1 , pp. 1253-1261
    • Benninger, M.S.1    Waters, H.2
  • 6
    • 4143054580 scopus 로고    scopus 로고
    • Allergic rhinitis and asthma: The link, the new ARIA classification and global approaches to treatment
    • DOI 10.1097/00130832-200402000-00002
    • Pawankar R. Allergic rhinitis and asthma: The link, the new ARIA classification and global approaches to treatment. Curr Opin All Clin Immunol 2004;4(1):1-4 (Pubitemid 39090046)
    • (2004) Current Opinion in Allergy and Clinical Immunology , vol.4 , Issue.1 , pp. 1-4
    • Pawankar, R.1
  • 8
    • 43749108171 scopus 로고    scopus 로고
    • British guideline on the management of asthma
    • British Thoracic Society
    • British Thoracic Society. British guideline on the management of asthma. Thorax 2008;63(4):1-121
    • (2008) Thorax , vol.63 , Issue.4 , pp. 1-121
  • 9
    • 39049170984 scopus 로고    scopus 로고
    • Global strategy for asthma management and prevention: GINA executive summary
    • Bateman ED, Hurd SS, Barnes PJ, et al. Global strategy for asthma management and prevention: GINA executive summary. Eur Respir J 2008;31(1):143-78
    • (2008) Eur Respir J , vol.31 , Issue.1 , pp. 143-178
    • Bateman, E.D.1    Hurd, S.S.2    Barnes, P.J.3
  • 10
    • 77957768543 scopus 로고    scopus 로고
    • Tiotropium bromide step-up therapy for adults with uncontrolled asthma
    • Peters SP, Kunselman SJ, Icitovic N, et al. Tiotropium bromide step-up therapy for adults with uncontrolled asthma. N Engl J Med 2010;363:1715-26
    • (2010) N Engl J Med , vol.363 , pp. 1715-1726
    • Peters, S.P.1    Kunselman, S.J.2    Icitovic, N.3
  • 12
    • 84857105984 scopus 로고    scopus 로고
    • Merck Frosst Canada. Research & Development: Major Accomplishments: Singulair. Available from
    • Merck Frosst Canada. (2011). Research & Development: Major Accomplishments: Singulair. Available from: Http://www.merckfrosst.ca/mfcl/en/ corporate/research/accomplishments/ singulair. html
    • (2011)
  • 13
    • 33746884316 scopus 로고    scopus 로고
    • Montelukast in pediatric asthma management
    • Walia M, Lodha R, Kabra SK. Montelukast in pediatric asthma management. Indian J Pediatr 2006;73(4):276-82
    • (2006) Indian J Pediatr , vol.73 , Issue.4 , pp. 276-282
    • Walia, M.1    Lodha, R.2    Kabra, S.K.3
  • 15
    • 0142074290 scopus 로고    scopus 로고
    • Montelukast and fluticasone compared with salmeterol and fluticasone in protecting against asthma exacerbation in adults: One year, double blind, randomised, comparative trial
    • Bjermer L, Bisgaard H, Bousquet J, et al. Montelukast and fluticasone compared with salmeterol and fluticasone in protecting against asthma exacerbation in adults: One year, double blind, randomised, comparative trial. BMJ 2003;327:891-7
    • (2003) BMJ , vol.327 , pp. 891-897
    • Bjermer, L.1    Bisgaard, H.2    Bousquet, J.3
  • 22
    • 0036044523 scopus 로고    scopus 로고
    • Anti-leukotriene agents compared to inhaled corticosteroids in the management of recurrent and/or chronic asthma in adults and children
    • Ducharme FM, Hicks GC. Anti-leukotriene agents compared to inhaled corticosteroids in the management of recurrent and/or chronic asthma in adults and children. Cochrane Database Syst Rev 2002;(3):CD002314
    • (2002) Cochrane Database Syst Rev , Issue.3
    • Ducharme, F.M.1    Hicks, G.C.2
  • 23
    • 0034538067 scopus 로고    scopus 로고
    • Fluticasone propionate/salmeterol combination provides more effective asthma control than low-dose inhaled corticosteroid plus montelukast
    • DOI 10.1067/mai.2000.110920
    • Nelson HS, Busse WW, Kerwin E, et al. Fluticasone propionate/salmeterol combination provides more effective asthma control than low-dose inhaled corticosteroid plus montelukast. J Allergy Clin Immunol 2000;106(6):1088-95 (Pubitemid 32006262)
    • (2000) Journal of Allergy and Clinical Immunology , vol.106 , Issue.6 , pp. 1088-1095
    • Nelson, H.S.1    Busse, W.W.2    Kerwin, E.3    Church, N.4    Emmett, A.5    Rickard, K.6    Knobil, K.7
  • 24
    • 0034821077 scopus 로고    scopus 로고
    • Salmeterol powder provides significantly better benefit than montelukast in asthmatic patients receiving concomitant inhaled corticosteroid therapy
    • DOI 10.1378/chest.120.2.423
    • Fish JE, Israel E, Murray JJ, et al. Salmeterol powder provides significantly better benefit than montelukast in asthmatic patients receiving concomitant inhaled corticosteroid therapy. Chest 2001;120(2):423-30 (Pubitemid 32881257)
    • (2001) Chest , vol.120 , Issue.2 , pp. 423-430
    • Fish, J.E.1    Israel, E.2    Murray, J.J.3    Emmett, A.4    Boone, R.5    Yancey, S.W.6    Rickard, K.A.7
  • 27
    • 0142074290 scopus 로고    scopus 로고
    • Montelukast and fluticasone compared with salmeterol and fluticasone in protecting against asthma exacerbation in adults: One year, double blind, randomised, comparative trial
    • Bjermer L, Bisgaard H, Bousquet J, et al. Montelukast and fluticasone compared with salmeterol and fluticasone in protecting against asthma exacerbation in adults: One year, double blind, randomised, comparative trial. BMJ 2003;327(7420):891
    • (2003) BMJ , vol.327 , Issue.7420 , pp. 891
    • Bjermer, L.1    Bisgaard, H.2    Bousquet, J.3
  • 28
    • 43949129790 scopus 로고    scopus 로고
    • Montelukast as add-on therapy to inhaled corticosteroids in the treatment of mild to moderate asthma: A systematic review
    • DOI 10.1136/thx.2007.081596
    • Joos S, Miksch A, Szecsenyi J, et al. Montelukast as add-on therapy to inhaled corticosteroids in the treatment of mild to moderate asthma: A systematic review. Thorax 2008;63(5):453-62 (Pubitemid 351698876)
    • (2008) Thorax , vol.63 , Issue.5 , pp. 453-462
    • Joos, S.1    Miksch, A.2    Szecsenyi, J.3    Wieseler, B.4    Grouven, U.5    Kaiser, T.6    Schneider, A.7
  • 30
    • 33745306721 scopus 로고    scopus 로고
    • Meta-analysis: Effect of long-acting β-agonists on severe asthma exacerbations and asthma-related deaths
    • Salpeter SR, Buckley NS, Ormiston TM, et al. Meta-analysis: Effect of long-acting beta-agonists on severe asthma exacerbations and asthma-related deaths. Ann Intern Med 2006;144(12):904-12 (Pubitemid 46768131)
    • (2006) Annals of Internal Medicine , vol.144 , Issue.12 , pp. 904-912
    • Salpeter, S.R.1    Buckley, N.S.2    Ormiston, T.M.3    Salpeter, E.E.4
  • 31
    • 77953635199 scopus 로고    scopus 로고
    • Addition of long-acting beta2-agonists to inhaled corticosteroids versus same dose inhaled corticosteroids for chronic asthma in adults and children
    • Ducharme FM, Ni Chroinin M, Greenstone I, et al. Addition of long-acting beta2-agonists to inhaled corticosteroids versus same dose inhaled corticosteroids for chronic asthma in adults and children. Cochrane Database Syst Rev 2010;(5):CD005535
    • (2010) Cochrane Database Syst Rev , Issue.5
    • Ducharme, F.M.1    Ni Chroinin, M.2    Greenstone, I.3
  • 32
    • 77952475795 scopus 로고    scopus 로고
    • Addition of long-acting beta2-agonists to inhaled steroids versus higher dose inhaled steroids in adults and children with persistent asthma
    • Ducharme FM, Ni Chroinin M, Greenstone I, et al. Addition of long-acting beta2-agonists to inhaled steroids versus higher dose inhaled steroids in adults and children with persistent asthma. Cochrane Database Syst Rev 2010;(4):CD005533
    • (2010) Cochrane Database Syst Rev , Issue.4
    • Ducharme, F.M.1    Ni Chroinin, M.2    Greenstone, I.3
  • 35
    • 0038638013 scopus 로고    scopus 로고
    • The relationship between asthma and allergic rhinitis: Exploring the basis for a common pathophysiology
    • DOI 10.1046/j.1472-9725.2003.00015.x
    • Vignola AM, Chanez P, Bousquet J. The relationship between asthma and allergic rhinitis: Exploring the basis for a common pathophysiology. Clin Exp Allergy Rev 2003;3:63-8 (Pubitemid 36528936)
    • (2003) Clinical and Experimental Allergy Reviews , vol.3 , Issue.2 , pp. 63-68
    • Vignola, A.M.1    Chanez, P.2    Bousquet, J.3
  • 36
    • 72549101807 scopus 로고    scopus 로고
    • Upper airway x 1: Allergic rhinitis and asthma: United disease through epithelial cells
    • Bourdin A, Gras D, Vachier I, Chanez P. Upper airway x 1: Allergic rhinitis and asthma: United disease through epithelial cells. Thorax 2009;64(11):999-1004
    • (2009) Thorax , vol.64 , Issue.11 , pp. 999-1004
    • Bourdin, A.1    Gras, D.2    Vachier, I.3    Chanez, P.4
  • 39
    • 0032109254 scopus 로고    scopus 로고
    • Co-existence of asthma and allergic rhinitis: A 23-year follow-up study of college students
    • Greisner WA, Settipane RJ, Settipane GA. Co-existence of asthma and allergic rhnitis: A 23-year follow-up study of college students. Allergy Asthma Proc 1998;19(4):185-8 (Pubitemid 128684482)
    • (1998) Allergy and Asthma Proceedings , vol.19 , Issue.4 , pp. 185-188
    • Settipane, R.J.1
  • 41
    • 17144432198 scopus 로고    scopus 로고
    • Effect of a concomitant diagnosis of allergic rhinitis on asthma-related health care use by adults
    • DOI 10.1111/j.1365-2222.2005.02182.x
    • Price D, Zhang Q, Kocevar VS, et al. Effect of a concomitant diagnosis of allergic rhinitis on asthma-related health care use by adults. Clin Exp Allergy 2005;35:282-7 (Pubitemid 40516652)
    • (2005) Clinical and Experimental Allergy , vol.35 , Issue.3 , pp. 282-287
    • Price, D.1    Zhang, Q.2    Kocevar, V.S.3    Yin, D.D.4    Thomas, M.5
  • 44
    • 33749044069 scopus 로고    scopus 로고
    • Efficacy and safety of montelukast in adults with asthma and allergic rhinitis
    • DOI 10.1016/j.rmed.2006.02.026, PII S0954611106001132
    • Virchow JC, Bachert C. Efficacy and safety of montelukast in adults with asthma and allergic rhinitis. Respir Med 2006;100(11):1952-9 (Pubitemid 44490289)
    • (2006) Respiratory Medicine , vol.100 , Issue.11 , pp. 1952-1959
    • Virchow, J.Chr.1    Bachert, C.2
  • 45
    • 76949100766 scopus 로고    scopus 로고
    • Montelukast as add-on therapy with inhaled corticosteroids or inhaled corticosteroids and long acting beta-2-agonist in the management of patients diagnosed with asthma and concurrent allergic rhinitis (the RADAR trial)
    • Keith PK, Koch C, Djandji M, et al. Montelukast as add-on therapy with inhaled corticosteroids or inhaled corticosteroids and long acting beta-2-agonist in the management of patients diagnosed with asthma and concurrent allergic rhinitis (the RADAR trial). Can Respir J 2009;16(Suppl A):17A-31A
    • (2009) Can Respir J , vol.16 , Issue.SUPPL. A
    • Keith, P.K.1    Koch, C.2    Djandji, M.3
  • 46
    • 78049431112 scopus 로고    scopus 로고
    • Real-life asthma care in Canada
    • McIvor RA, Sampalis J. Real-life asthma care in Canada. Can Respir J 2009;16(Suppl A):3A-6A
    • (2009) Can Respir J , vol.16 , Issue.SUPPL. A
    • McIvor, R.A.1    Sampalis, J.2
  • 47
    • 10944232455 scopus 로고    scopus 로고
    • How representative are clinical study patients with asthma or COPD for a larger "real life" population of patients with obstructive lung disease?
    • DOI 10.1016/j.rmed.2004.03.026, PII S0954611104002069
    • Herland K, Akselsen JP, Skjonsberg OH, et al. How representative are clinical study patients with asthma or COPD for a larger 'real life' population of patients with obstructive lung disease? Respir Med 2005;99:11-19 (Pubitemid 40017378)
    • (2005) Respiratory Medicine , vol.99 , Issue.1 , pp. 11-19
    • Herland, K.1    Akselsen, J.-P.2    Skjonsberg, O.H.3    Bjermer, L.4
  • 48
    • 21244473242 scopus 로고    scopus 로고
    • Improving asthma control in patients suboptimally controlled on inhaled steroids and long acting beta agonists: The addition of montelukast in an open-label pilot study
    • Dupont L, Potvin E, Korn D. Improving asthma control in patients suboptimally controlled on inhaled steroids and long acting beta agonists: The addition of montelukast in an open-label pilot study. Curr Med Res Opin 2005;21(6):863-942
    • (2005) Curr Med Res Opin , vol.21 , Issue.6 , pp. 863-942
    • Dupont, L.1    Potvin, E.2    Korn, D.3
  • 49
    • 64249140278 scopus 로고    scopus 로고
    • Efficacy of add-on montelukast in patients with non-controlled asthma: A Belgian open label study
    • Korn D, Van den Brande D, Potvin E, et al. Efficacy of add-on montelukast in patients with non-controlled asthma: A Belgian open label study. Curr Med Res Opin 2009;25(2):489-97
    • (2009) Curr Med Res Opin , vol.25 , Issue.2 , pp. 489-497
    • Korn, D.1    Van Den Brande, D.2    Potvin, E.3
  • 50
    • 77951758049 scopus 로고    scopus 로고
    • Montelukast as add-on therapy to inhaled corticosteroids in the management of asthma (SAS trial)
    • FitzGerald JM, Foucart S, Coyle S, et al. Montelukast as add-on therapy to inhaled corticosteroids in the management of asthma (SAS trial). Can Respir J 2009;16(Suppl A):5A-14A
    • (2009) Can Respir J , vol.16 , Issue.SUPPL. A
    • FitzGerald, J.M.1    Foucart, S.2    Coyle, S.3
  • 51
    • 77951620096 scopus 로고    scopus 로고
    • Add-on montelukast in inadequately controlled asthma patients in a 6 month open label study: The montelukast in chronic asthma (MONICA) study
    • Virchow JC, Mehta A, Ljungblad L, Mitfessel H. Add-on montelukast in inadequately controlled asthma patients in a 6 month open label study: The montelukast in chronic asthma (MONICA) study. Respir Med 2010;104(5):644-51
    • (2010) Respir Med , vol.104 , Issue.5 , pp. 644-651
    • Virchow, J.C.1    Mehta, A.2    Ljungblad, L.3    Mitfessel, H.4
  • 52
    • 76949090418 scopus 로고    scopus 로고
    • Evaluation of 3-5 months' add-on therapy with montelukast in patients with non-controlled asthma in Austria: The STAR open-label, real world, observational study
    • Schlick W, Pohl W, Pfeiffer KP, et al. Evaluation of 3-5 months' add-on therapy with montelukast in patients with non-controlled asthma in Austria: The STAR open-label, real world, observational study. Curr Med Res Opin 2010;26(3):561-70
    • (2010) Curr Med Res Opin , vol.26 , Issue.3 , pp. 561-570
    • Schlick, W.1    Pohl, W.2    Pfeiffer, K.P.3
  • 53
    • 80051489833 scopus 로고    scopus 로고
    • Montelukast as an alternative to low-dose inhaled corticosteroids in the management of asthma (SIMPLE trial)
    • McIvor RA, Kaplan A, Koch C, et al. Montelukast as an alternative to low-dose inhaled corticosteroids in the management of asthma (SIMPLE trial). Can Respir J 2009;16(Suppl A):5A-14A
    • (2009) Can Respir J , vol.16 , Issue.SUPPL. A
    • McIvor, R.A.1    Kaplan, A.2    Koch, C.3
  • 56
    • 76549137094 scopus 로고    scopus 로고
    • Association between leukotriene receptor antagonist therapy and Churg-Strauss syndrome: An analysis of the FDA AERS database
    • S Bibby S, Healy B, Steele R, et al. Association between leukotriene receptor antagonist therapy and Churg-Strauss syndrome: An analysis of the FDA AERS database. Thorax 2010;65:132-8
    • (2010) Thorax , vol.65 , pp. 132-138
    • S Bibby, S.1    Healy, B.2    Steele, R.3
  • 58
    • 84857105986 scopus 로고    scopus 로고
    • US Food and Drug Administration. Updated information on leukotriene inhibitors. Available from
    • US Food and Drug Administration. (2010). Updated information on leukotriene inhibitors. Available from: Http://www.fda.gov/Drugs/DrugSafety/ PostmarketDrugSafetyInformationfor PatientsandProviders/ DrugSafetyInformationforHeathcare Professionals/ucm165489.htm
    • (2010)
  • 60
    • 74549216073 scopus 로고    scopus 로고
    • Utility of exhaled nitric oxide in the diagnosis and management of asthma
    • Majid H, Kao C. Utility of exhaled nitric oxide in the diagnosis and management of asthma. Curr Opin Pulm Med 2010;16(1):42-7
    • (2010) Curr Opin Pulm Med , vol.16 , Issue.1 , pp. 42-47
    • Majid, H.1    Kao, C.2
  • 61
    • 21244436401 scopus 로고    scopus 로고
    • Safety, tolerability, and exploratory efficacy of montelukast in 6- to 24-month-old patients with asthma
    • Van Adelsberg J, Moy J, Wei LX, et al. Safety, tolerability, and exploratory efficacy of montelukast in 6- to 24-month-old patients with asthma. Curr Med Res Opin 2005;21(6):971-9
    • (2005) Curr Med Res Opin , vol.21 , Issue.6 , pp. 971-919
    • Van Adelsberg, J.1    Moy, J.2    Wei, L.X.3
  • 62
    • 78649256828 scopus 로고    scopus 로고
    • A phase I randomized, placebo-controlled, dose-exploration study of single-dose inhaled montelukast in patients with chronic asthma
    • Philip G, Pedinoff A, Vandormael K, et al. A phase I randomized, placebo-controlled, dose-exploration study of single-dose inhaled montelukast in patients with chronic asthma. J Asthma 2010;47(10):1078-84
    • (2010) J Asthma , vol.47 , Issue.10 , pp. 1078-1084
    • Philip, G.1    Pedinoff, A.2    Vandormael, K.3
  • 63
    • 76649089020 scopus 로고    scopus 로고
    • A randomized placebo-controlled study of intravenous montelukast in children with acute asthma
    • Morris CR, Becker AB, Pinieiro A, et al. A randomized, placebo-controlled study of intravenous montelukast in children with acute asthma. Ann Allergy Asthma Immunol 2010;104(2):161-71
    • (2010) Ann Allergy Asthma Immunol , vol.104 , Issue.2 , pp. 161-171
    • Morris, C.R.1    Becker, A.B.2    Pinieiro, A.3
  • 64
    • 75849157844 scopus 로고    scopus 로고
    • A randomized placebo-controlled study of intravenous montelukast for the treatment of acute asthma
    • Camargo CA Jr, Gurner DM, Smithline HA, et al. A randomized placebo-controlled study of intravenous montelukast for the treatment of acute asthma. J Allergy Clin Immunol 2010;125(2):374-80
    • (2010) J Allergy Clin Immunol , vol.125 , Issue.2 , pp. 374-380
    • Camargo Jr., C.A.1    Gurner, D.M.2    Smithline, H.A.3
  • 65
    • 0031110457 scopus 로고    scopus 로고
    • Randomized trial of zileuton in patients with moderate asthma: Effect of reduced dosing frequency and amounts on pulmonary function and asthma symptoms
    • DuBuske LM, Grossman J, Dube LM, et al. Randomized trial of zileuton in patients with moderate asthma: Effect of reduced dosing frequency and amounts on pulmonary function and asthma symptoms. Am J Manag Care 1997;3(4):633-40 (Pubitemid 127528789)
    • (1997) American Journal of Managed Care , vol.3 , Issue.4 , pp. 633-640
    • DuBuske, L.M.1    Grossman, J.2    Dube, L.M.3    Swanson, L.J.4    Lancaster, J.F.5


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