Decreased miR-192 expression in peripheral blood of asthmatic individuals undergoing an allergen inhalation challenge

BMC Genomics

Volumn 13, Issue 1, 2012, Pages

  Yamamoto, Masatsugu ^a,b,c   Singh, Amrit ^a,b,d   Ruan, Jian ^a,b   Gauvreau, Gail M ^e   O'Byrne, Paul M ^e   Carlsten, Christopher R ^a,b,c   FitzGerald, J Mark ^a,b,c   Boulet, Louis Philippe ^f   Tebbutt, Scott J ^a,b,d  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b Institute for HEART+LUNG Health   (Canada)

^c VANCOUVER GENERAL HOSPITAL   (Canada)

^d NCE CECR PROOF Centre of Excellence   (Canada)

^e MCMASTER UNIVERSITY   (Canada)

^f UNIVERSITÉ LAVAL   (Canada)

Author keywords

Allergen inhalation challenge; Allergy; Asthma; Blood cells; Hsa miR 192; MicroRNAs; NanoString nCounter assay

Indexed keywords

ALLERGEN; MICRORNA 192;

ADULT; ARTICLE; ASTHMA; BLOOD SAMPLING; CELL CYCLE; CELL SPECIFICITY; CLINICAL ARTICLE; CONTROLLED STUDY; DENATURATION; FEMALE; GENE EXPRESSION; GENE FUNCTION; GENE TARGETING; HUMAN; IMMUNE RESPONSE; INHALATION TEST; MALE; PERIPHERAL BLOOD MONONUCLEAR CELL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VALIDATION PROCESS;

ADMINISTRATION, INHALATION; ADULT; ALLERGENS; ASTHMA; BLOOD CELL COUNT; FEMALE; HUMANS; MALE; MICRORNAS; MIDDLE AGED; UP-REGULATION; YOUNG ADULT;

EID: 84869208079     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/1471-2164-13-655     Document Type: Article

References (29)

1. Gauvreau GM, Evans MY. Allergen inhalation challenge: a human model of asthma exacerbation. Contrib Microbiol 2007, 14:21-32.
2. Kam SH, Singh A, He JQ, Ruan J, Gauvreau GM, O'Byrne PM, Fitzgerald JM, Tebbutt SJ. Peripheral blood gene expression changes during allergen inhalation challenge in atopic asthmatic individuals. J Asthma 2012, 49(3):219-226. 10.3109/02770903.2011.654300, 22316092.
3. Chaussabel D, Pascual V, Banchereau J. Assessing the human immune system through blood transcriptomics. BMC Biol 2010, 8:84. 10.1186/1741-7007-8-84, 2895587, 20619006.
4. Esteller M. Non-coding RNAs in human disease. Nat Rev Genet 2011, 12(12):861-874. 10.1038/nrg3074, 22094949.
5. Garbacki N, Di Valentin E, Huynh-Thu VA, Geurts P, Irrthum A, Crahay C, Arnould T, Deroanne C, Piette J, Cataldo D, et al. MicroRNAs profiling in murine models of acute and chronic asthma: a relationship with mRNAs targets. PLoS One 2011, 6(1):e16509. 10.1371/journal.pone.0016509, 3030602, 21305051.
6. Lu TX, Munitz A, Rothenberg ME. MicroRNA-21 is up-regulated in allergic airway inflammation and regulates IL-12p35 expression. J Immunol 2009, 182(8):4994-5002. 10.4049/jimmunol.0803560, 19342679.
7. Williams AE, Larner-Svensson H, Perry MM, Campbell GA, Herrick SE, Adcock IM, Erjefalt JS, Chung KF, Lindsay MA. MicroRNA expression profiling in mild asthmatic human airways and effect of corticosteroid therapy. PLoS One 2009, 4(6):e5889. 10.1371/journal.pone.0005889, 2690402, 19521514.
8. Jardim MJ, Dailey L, Silbajoris R, Diaz-Sanchez D. Distinct MicroRNA expression in human airway cells of asthmatic donors identifies a novel asthma-associated gene. Am J Respir Cell Mol Biol 2012, 47(4):536-542. 10.1165/rcmb.2011-0160OC, 22679274.
9. Song B, Wang Y, Kudo K, Gavin EJ, Xi Y, Ju J. miR-192 Regulates dihydrofolate reductase and cellular proliferation through the p53-microRNA circuit. Clin Cancer Res 2008, 14(24):8080-8086. 10.1158/1078-0432.CCR-08-1422, 2653201, 19088023.
10. Izzotti A, Calin GA, Arrigo P, Steele VE, Croce CM, De Flora S. Downregulation of microRNA expression in the lungs of rats exposed to cigarette smoke. FASEB J 2009, 23(3):806-812. 10.1096/fj.08-121384, 2653990, 18952709.
11. Wang G, Tam LS, Li EK, Kwan BC, Chow KM, Luk CC, Li PK, Szeto CC. Serum and urinary free microRNA level in patients with systemic lupus erythematosus. Lupus 2011, 20(5):493-500. 10.1177/0961203310389841, 21372198.
12. Krupa A, Jenkins R, Luo DD, Lewis A, Phillips A, Fraser D. Loss of MicroRNA-192 promotes fibrogenesis in diabetic nephropathy. J Am Soc Nephrol 2010, 21(3):438-447. 10.1681/ASN.2009050530, 2831862, 20056746.
13. Torrego A, Hew M, Oates T, Sukkar M, Fan Chung K. Expression and activation of TGF-beta isoforms in acute allergen-induced remodelling in asthma. Thorax 2007, 62(4):307-313. 10.1136/thx.2006.063487, 1892798,1892798, 17251317.
14. Shen-Orr SS, Tibshirani R, Khatri P, Bodian DL, Staedtler F, Perry NM, Hastie T, Sarwal MM, Davis MM, Butte AJ. Cell type-specific gene expression differences in complex tissues. Nat Methods 2010, 7(4):287-289. 10.1038/nmeth.1439, 20208531.
15. Shannon CP, Hollander Z, Wilson-McManus J, Balshaw R, Ng RT, McMaster R, McManus BM, Keown PA, Tebbutt SJ. White blood cell differentials enrich whole blood expression data in the context of acute cardiac allograft rejection. Bioinform Biol Insights 2012, 6:49-61. 3329187, 22550401.
16. Tebbutt SJ, He JQ, Singh A, Shannon CP, Ruan J, Carlsten C. Transcriptional changes of blood eosinophils after methacholine inhalation challenge in asthmatics. Genomics Insights 2012, 5:1-12.
17. Rossi RL, Rossetti G, Wenandy L, Curti S, Ripamonti A, Bonnal RJ, Birolo RS, Moro M, Crosti MC, Gruarin P, et al. Distinct microRNA signatures in human lymphocyte subsets and enforcement of the naive state in CD4+ T cells by the microRNA miR-125b. Nat Immunol 2011, 12(8):796-803. 10.1038/ni.2057, 21706005.
18. Lawrie CH, Saunders NJ, Soneji S, Palazzo S, Dunlop HM, Cooper CD, Brown PJ, Troussard X, Mossafa H, Enver T, et al. MicroRNA expression in lymphocyte development and malignancy. Leukemia 2008, 22(7):1440-1446. 10.1038/sj.leu.2405083, 18185523.
19. Gerblich AA, Campbell AE, Schuyler MR. Changes in T-lymphocyte subpopulations after antigenic bronchial provocation in asthmatics. N Engl J Med 1984, 310(21):1349-1352. 10.1056/NEJM198405243102103, 6232459.
20. Gerblich AA, Salik H, Schuyler MR. Dynamic T-cell changes in peripheral blood and bronchoalveolar lavage after antigen bronchoprovocation in asthmatics. Am Rev Respir Dis 1991, 143(3):533-537.
21. Wilson JW, Djukanovic R, Howarth PH, Holgate ST. Lymphocyte activation in bronchoalveolar lavage and peripheral blood in atopic asthma. Am Rev Respir Dis 1992, 145(4 Pt 1):958-960.
22. Krejsek J, Kral B, Vokurkova D, Derner V, Touskova M, Parakova Z, Kopecky O. Decreased peripheral blood gamma delta T cells in patients with bronchial asthma. Allergy 1998, 53(1):73-77. 10.1111/j.1398-9995.1998.tb03776.x, 9491232.
23. Hallstrand TS, Ault KA, Bates PW, Mitchell J, Schoene RB. Peripheral blood manifestations of T(H)2 lymphocyte activation in stable atopic asthma and during exercise-induced bronchospasm. Ann Allergy Asthma Immunol 1998, 80(5):424-432. 10.1016/S1081-1206(10)62996-1, 9609615.
24. Gauvreau GM, Hessel EM, Boulet LP, Coffman RL, O'Byrne PM. Immunostimulatory sequences regulate interferon-inducible genes but not allergic airway responses. Am J Respir Crit Care Med 2006, 174(1):15-20. 10.1164/rccm.200601-057OC, 16574937.
25. Crapo RO, Casaburi R, Coates AL, Enright PL, Hankinson JL, Irvin CG, MacIntyre NR, McKay RT, Wanger JS, Anderson SD, et al. Guidelines for methacholine and exercise challenge testing-1999. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors, July 1999. Am J Respir Crit Care Med 2000, 161(1):309-329.
26. Cockcroft DW, Murdock KY, Kirby J, Hargreave F. Prediction of airway responsiveness to allergen from skin sensitivity to allergen and airway responsiveness to histamine. Am Rev Respir Dis 1987, 135(1):264-267.
27. O'Byrne PM, Dolovich J, Hargreave FE. Late asthmatic responses. Am Rev Respir Dis 1987, 136(3):740-751. 10.1164/ajrccm/136.3.740, 3115156.
28. Geiss GK, Bumgarner RE, Birditt B, Dahl T, Dowidar N, Dunaway DL, Fell HP, Ferree S, George RD, Grogan T, et al. Direct multiplexed measurement of gene expression with color-coded probe pairs. Nat Biotechnol 2008, 26(3):317-325. 10.1038/nbt1385, 18278033.
29. Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, et al. Bioconductor: open software development for computational biology and bioinformatics. Genome Biol 2004, 5(10):R80. 10.1186/gb-2004-5-10-r80, 545600, 15461798.