Phosphoinositide-dependent kinase 1 provides negative feedback inhibition to toll-like receptor-mediated NF-κB activation in macrophages

Molecular and Cellular Biology

Volumn 30, Issue 17, 2010, Pages 4354-4366

  Chaurasia, Bhagirath ^a,b,c   Mauer, Jan ^a,b,c   Koch, Linda ^a,b,c   Goldau, Julia ^a,b,c   Kock, Anja Sterner ^b   Brüning, Jens C ^a,b,c  

^a UNIVERSITY OF COLOGNE   (Germany)

^b UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

^c MAX PLANCK INSTITUTE FOR BIOLOGY OF AGEING   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PROTEIN KINASE B; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR AGONIST; TOLL LIKE RECEPTOR AGONIST PAM3CSK4; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG; 3 PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE; 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE; CYTOKINE; LIPOPEPTIDE; MITOGEN ACTIVATED PROTEIN KINASE; PAM(3)CSK(4) PEPTIDE; PROTEIN SERINE THREONINE KINASE; TOLL LIKE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; CELL COMPOSITION; CELL LINEAGE; CONTROLLED STUDY; DISEASE PREDISPOSITION; DNA FLANKING REGION; LIVER FAILURE; MACROPHAGE; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; PERITONEAL CAVITY; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SEPTIC SHOCK; UBIQUITINATION; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; CELL CULTURE; CHEMICALLY INDUCED DISORDER; DRUG ANTAGONISM; GENE DELETION; GENETICS; IMMUNOLOGY; LIVER; METABOLISM; PATHOLOGY; SEPSIS;

MUS;

ANIMALS; CELLS, CULTURED; CYTOKINES; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE DELETION; LIPOPEPTIDES; LIPOPOLYSACCHARIDES; LIVER; MACROPHAGES; MICE; MICE, INBRED C57BL; MYELOID CELLS; NF-KAPPA B; PROTEIN-SERINE-THREONINE KINASES; SEPSIS; TNF RECEPTOR-ASSOCIATED FACTOR 6; TOLL-LIKE RECEPTORS; TUMOR NECROSIS FACTOR-ALPHA; UBIQUITINATION;

EID: 77956627302     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.00069-10     Document Type: Article

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