Myeloid cell-restricted insulin receptor deficiency protects against obesity-induced inflammation and systemic insulin resistance

PLoS Genetics

Volumn 6, Issue 5, 2010, Pages 38-

  Mauer, Jan ^a   Chaurasia, Bhagirath ^a   Plum, Leona ^a   Quast, Thomas ^b   Hampel, Brigitte ^a   Blüher, Matthias ^c   Kolanus, Waldemar ^b   Kahn, C Ronald ^d   Brüning, Jens C ^a,e,f  

^a UNIVERSITY OF COLOGNE   (Germany)

^b UNIVERSITY OF BONN   (Germany)

^c UNIVERSITY OF LEIPZIG   (Germany)

^d HARVARD MEDICAL SCHOOL   (United States)

^e UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

^f MAX PLANCK INSTITUTE FOR BIOLOGY OF AGEING   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE B; INSULIN RECEPTOR; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CELL LINEAGE; CONTROLLED STUDY; ENZYME ACTIVITY; GLUCONEOGENESIS; GLUCOSE METABOLISM; INFLAMMATION; INSULIN RESISTANCE; LIPID DIET; MACROPHAGE; MONOCYTE; MOUSE; NONHUMAN; OBESITY; PROTEIN EXPRESSION; SKELETAL MUSCLE; ANIMAL; C57BL MOUSE; CELL CULTURE; DISEASE MODEL; FEMALE; GENETICS; HUMAN; IMMUNOLOGY; LIVER; MALE; METABOLISM; MOUSE MUTANT;

ANIMALIA; MUS;

ANIMALS; CELLS, CULTURED; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; INSULIN RESISTANCE; LIVER; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MONOCYTES; MUSCLE, SKELETAL; OBESITY; RECEPTOR, INSULIN;

EID: 77953226127     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1000938     Document Type: Article

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