Increased diacylglycerol kinase ζ expression in human metastatic colon cancer cells augments Rho GTPase activity and contributes to enhanced invasion

BMC Cancer

Volumn 14, Issue 1, 2014, Pages

  Cai, Kun ^a   Mulatz, Kirk ^a   Ard, Ryan ^a,b   Nguyen, Thanh ^a   Gee, Stephen H ^a  

^a UNIVERSITY OF OTTAWA   (Canada)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Colon carcinoma; Diacylglycerol kinase; Metastasis; Rho GTPase

Indexed keywords

DIACYLGLYCEROL KINASE; DIACYLGLYCEROL KINASE ZETA; P21 ACTIVATED KINASE 1; RAC1 PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; COLORECTAL CARCINOMA; CONTROLLED STUDY; DGKZETA GENE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; METASTATIC COLORECTAL CANCER; PROSTATE CANCER; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TUMOR INVASION;

CELL LINE, TUMOR; CELL MOVEMENT; COLONIC NEOPLASMS; DIACYLGLYCEROL KINASE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; HUMANS; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; P21-ACTIVATED KINASES; PHOSPHORYLATION; RAC1 GTP-BINDING PROTEIN; RHOA GTP-BINDING PROTEIN;

EID: 84899095002     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-14-208     Document Type: Article

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