Protein kinase C regulates the nuclear localization of diacylglycerol kinase-ζ

Nature

Volumn 394, Issue 6694, 1998, Pages 697-700

  Topham, Matthew K ^a,b,c   Bunting, Michaeline ^a,b,c   Zimmerman, Guy A ^c   McIntyre, Thomas M ^c   Blackshear, Perry J ^d   Prescott, Stephen M ^a,b,c  

^a UNIVERSITY OF UTAH   (United States)

^b UNIVERSITY OF UTAH   (United States)

^c UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^d NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; DIACYLGLYCEROL; DIACYLGLYCEROL KINASE; MARCKS PROTEIN; NUCLEAR PROTEIN; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHATIDIC ACID; PROTEIN KINASE C;

ANIMAL CELL; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; BIOLOGICAL TRANSPORT; CELL CYCLE; CELL NUCLEUS; COS CELLS; DIACYLGLYCEROL KINASE; DIGLYCERIDES; ENZYME ACTIVATION; GREEN FLUORESCENT PROTEINS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LUMINESCENT PROTEINS; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; PHOSPHORYLATION; PROTEIN KINASE C; PROTEINS; TRANSFECTION; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 0032514484     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/29337     Document Type: Article

References (29)

1. Goto, K. & Kondo, H. Molecular cloning and expression of a 90-kDa diacylglycerol kinase that predominantly localizes in neurons. Proc. Natl Acad. Sci. USA 90, 7598-7602 (1993).
2. Kai, M., Sakane, F., Imai, S.-i., Wada, I. & Kanoh, M. Molecular cloning of a diacylglycerol kinase isozyme predominantly expressed in human retina with a truncated and inactive enzyme expression in most other human cells. J. Biol. Chem. 269, 18492-18498 (1994).
3. Sakane, F., Yamada, K., Kanoh, H., Yokoyama, C. & Tanabe, T. Porcine diacylglycerol kinase sequence has zinc finger and E-F hand motifs. Nature 344, 345-348 (1990).
4. Houssa, B. et al. Cloning of a novel human diacylglycerolkinase (DGKθ) containing three cysteinerich domains, a proline-rich region and a pleckstrin homology domain with overlapping rasassociating domain. J. Biol. Chem. 272, 10422-10428 (1997).
5. Klauck, T. M., Xu, X., Mousseau, B. & Jaken, S. Cloning and characterization of a glucocorticoid-induced diacylglycerol kinase. J. Biol. Chem. 271, 19871-19788 (1996).
6. Sakane, F., Imai, S. I., Kai, M., Wada, I. & Kanoh, H. Molecular cloning of a novel diacylglycerol kinase isozyme with a pleckstrin homology domain and a C-terminal tail similar to those of the EPH family of protein tyrosine kinases. J. Biol. Chem. 271, 8394-8401 (1996).
7. Bunting, M., Tang, W., Zimmerman, G. A., McIntyre, T. M. & Prescott, S. M. Molecular cloning and characterization of a novel human diacylglycerol kinase ζ. J. Biol. Chem. 271, 10230-10236 (1996).
8. Tang, W., Bunting, M., Zimmerman, G. A., McIntyre, T. M. & Prescott, S. M. Molecular cloning of a novel human diacylglycerol kinase highly selective for arachidonate-containing substrates. J. Biol. Chem. 271, 10237-10241 (1996).
9. Jackowski, S. Cell cycle regulation of membrane phospholipid metabolism. J. Biol. Chem. 271, 20219-20222 (1996).
10. Olson, E. N., Burgess, R. & Staudinger, J. Protein kinase C as a transducer of nuclear signals. Cell Growth Differ. 4, 699-705 (1993).
11. Aderem, A. The MARCKS brothers: a family of protein kinase C substrates. Cell 71, 713-716 (1992).
12. Blackshear, P. J. The MARCKS family of cellular protein kinase C substrates. J. Biol. Chem. 268, 1501-1504 (1993).
13. Verghese, G. M. et al. Protein kinase C-mediated phosphorylation and calmodulin binding of recombinant MARCKS and MARCKS-related protein (MRP). J. Biol. Chem. 269, 9361-9367 (1994).
14. Graff, J. M., Rajan, R. R., Randall, R. R., Nairn, A. C. & Blackshear, P. J. Protein kinase C substrate and inhibitor characteristics of peptides from the myristoylated alanine-rich C kinase substrate (MARCKS) protein phosphorylation site domain. J. Biol. Chem. 266, 14390-14398 (1991).
15. Herget, T., Oehrlein, S. A., Pappin, D. J. C., Rozengurt, E. & Parker, P. J. The myristoylated alanine-rich C-kinase substrate (MARCKS) is sequentially phosphorylated by conventional, novel and atypical isotypes of protein kinase C. Eur. J. Biochem. 233, 448-457 (1995).
16. Xiao, H., Goldthwait, D. A. & Mapstone, T. The identification of four protein kinase C isoforms in human glioblastoma cell lines: PKC alpha, gamma, epsilon, and zeta. J. Neurosurg. 81, 734-740 (1994).
17. Divecha, N., Banfic, H. & Irvine, R. F. Inositides and the nucleus and inositides in the nucleus. Cell 74, 405-407 (1993).
18. Divecha, N., Banfic, H. & Irvine, R. F. The polyphosphoinositide cycle exists in the nuclei of Swiss 3T3 cells under the control of a receptor (for IGE-1) in the plasma membrane, and stimulation of the cycle increases nuclear diacylglycerol and apparently induces translocation of protein kinase C to the nucleus. EMBO J. 10, 3207-3214 (1991).
19. Banfic, H., Zizak, M., Divecha, N. & Irvine, R. F. Nuclear diacylglycerol is increased during cell proliferation in vivo. Biochem. J. 290, 633-636 (1993).
20. Leach, K. L. et al. α-Thrombin stimulates nuclear diglyceride levels and differential nuclear localization of protein kinase C isozymes in IIC9 cells. J. Biol. Chem. 267, 21816-21822 (1992).
21. Swierczynski, S. L. & Blackshear, P. J. Myristoylation-dependent and electrostatic interactions exert independent effects on the membrane association of the myristoylated alanine-rich protein kinase C substrate protein in intact cells. J. Biol. Chem. 271, 23424-23430 (1996).
22. Sun, B., Murray, N. R. & Fields, A. P. A role for nuclear phosphatidylinositol-specific phospholipase C in the G2/M phase transition. J. Biol. Chem. 272, 26313-26317 (1997).
23. Divecha, N., Rhee, S.-G., Letcher, A. J. & Irvine, R. F. Phosphoinositide signalling in rat liver nuclei: phosphoinositidase C isoform β1 is specifically, but not predominantly, located in the nucleus. Biochem. J. 289, 617-620 (1993).
24. Ding, L. et al. Alternative splicing of the human diacylglycerol kinase zeta gene in muscle. Proc. Natl Acad. Sci. USA 94, 5519-5524 (1997).
25. Payrastre, B. et al. A differential location of phosphoinositide kinases, diacylglycerol kinase, and phospholipase C in the nuclear matrix. J. Biol. Chem. 267, 5078-5084 (1992).
26. York, J. & Majerus, P. W. Nuclear phosphatidylinositols decrease during S-phase of the cell cycle in HeLa cells. J. Biol. Chem. 269, 7847-7850 (1994).
27. Bligh, E. G. & Dyer, W. J. A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 37, 911-917 (1959).
28. Whatley, R. E. et al. Growth-dependent changes in arachidonic acid release from endothelial cells are mediated by protein kinase C and changes in diacylglycerol. J. Biol. Chem. 268, 16130-16138 (1993).
29. Halsey, D. L., Girard, P. R., Kuo, J. F. & Blackshear, P. J. Protein kinase C in fibroblasts. Characteristics of its membrane association during growth and after exposure to phorbol esters and other mitogens. J. Biol. Chem. 262, 2234-2243 (1987).