DhhP, a cyclic di-AMP phosphodiesterase of Borrelia burgdorferi, is essential for cell growth and virulence

Infection and Immunity

Volumn 82, Issue 5, 2014, Pages 1840-1849

  Ye, Meiping ^a,b   Zhang, Jun Jie ^b,c   Fang, Xin ^d   Lawlis, Gavin B ^d   Troxell, Bryan ^b   Zhou, Yan ^a   Gomelsky, Mark ^d   Lou, Yongliang ^a   Yang, X Frank ^a,b  

^a WENZHOU MEDICAL UNIVERSITY   (China)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c WUHAN INSTITUTE OF VIROLOGY   (China)

^d UNIVERSITY OF WYOMING   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ENZYME; BETA LACTAM ANTIBIOTIC; CYCLIC AMP PHOSPHODIESTERASE; CYCLIC DI AMP PHOSPHODIESTERASE; DHHP PROTEIN; MAGNESIUM; MANGANESE; RECOMBINANT ENZYME; SIGMA FACTOR RPOS; UNCLASSIFIED DRUG; VIRULENCE FACTOR; VIRULENCE FACTOR OSPC;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL CELL; BACTERIAL GROWTH; BACTERIAL VIRULENCE; BACTERIUM MUTANT; BORRELIA BURGDORFERI; CELL GROWTH; CELL LEVEL; CONTROLLED STUDY; GENE INACTIVATION; GRAM POSITIVE BACTERIUM; HYDROLYSIS; IN VITRO STUDY; INTRACELLULAR SPACE; MAMMAL; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SPIROCHETE; WILD TYPE;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTIGENS, BACTERIAL; BACTERIAL OUTER MEMBRANE PROTEINS; BACTERIAL PROTEINS; BACTERIOLOGICAL TECHNIQUES; BORRELIA BURGDORFERI; DRUG RESISTANCE, BACTERIAL; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GENE DELETION; GENE EXPRESSION REGULATION, BACTERIAL; IMMUNOBLOTTING; LYME DISEASE; MICE; PHOSPHORIC DIESTER HYDROLASES; PROTEIN STRUCTURE, TERTIARY; SIGNAL TRANSDUCTION; VIRULENCE;

EID: 84898838674     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00030-14     Document Type: Article

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