Mechanisms shaping the naïve T cell repertoire in the elderly - Thymic involution or peripheral homeostatic proliferation?

Experimental Gerontology

Volumn 54, Issue , 2014, Pages 71-74

  Qi, Qian ^a,b   Zhang, David W ^a,b   Weyand, Cornelia M ^a,b   Goronzy, Jörg J ^a,b  

^a VA PALO ALTO HEALTH CARE SYSTEM   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Aging; Immunosenescence; T cell receptor repertoire; T cells; Thymus

Indexed keywords

T LYMPHOCYTE RECEPTOR; LYMPHOCYTE ANTIGEN RECEPTOR;

AGE; AGING; ARTICLE; CLONAL VARIATION; HOMEOSTASIS; HUMAN; LYMPHOCYTE PROLIFERATION; MOUSE; NEXT GENERATION SEQUENCING; NONHUMAN; PRIORITY JOURNAL; SPECIES DIFFERENCE; STATISTICAL MODEL; T LYMPHOCYTE; THYMUS; ADULT; AGED; ANIMAL; CELL PROLIFERATION; MIDDLE AGED; PHYSIOLOGY; T LYMPHOCYTE SUBPOPULATION;

MUS;

ADULT; AGED; ANIMALS; CELL PROLIFERATION; HOMEOSTASIS; HUMANS; MICE; MIDDLE AGED; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES; THYMUS GLAND;

EID: 84898788764     PISSN: 05315565     EISSN: 18736815     Source Type: Journal    
DOI: 10.1016/j.exger.2014.01.005     Document Type: Article

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