-
1
-
-
0027257499
-
How diverse should the immune system be?
-
de Boer RJ, Perelson AS. How diverse should the immune system be? Proc Biol Sci 1993; 252:171-5.
-
(1993)
Proc Biol Sci
, vol.252
, pp. 171-175
-
-
de Boer, R.J.1
Perelson, A.S.2
-
2
-
-
0033615678
-
A direct estimate of the human αβ T cell receptor diversity
-
Arstila TP, Casrouge A, Baron V, Even J, Kanellopoulos J, Kourilsky P. A direct estimate of the human αβ T cell receptor diversity. Science 1999; 286:958-61.
-
(1999)
Science
, vol.286
, pp. 958-961
-
-
Arstila, T.P.1
Casrouge, A.2
Baron, V.3
Even, J.4
Kanellopoulos, J.5
Kourilsky, P.6
-
4
-
-
84867095375
-
Statistical inference of the generation probability of T-cell receptors from sequence repertoires
-
Murugan A, Mora T, Walczak AM, Callan CG. Statistical inference of the generation probability of T-cell receptors from sequence repertoires. Proc Natl Acad Sci U S A 2012; 109:16161-6.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 16161-16166
-
-
Murugan, A.1
Mora, T.2
Walczak, A.M.3
Callan, C.G.4
-
5
-
-
0023720148
-
T-cell antigen receptor genes and T-cell recognition
-
Davis MM, Bjorkman PJ. T-cell antigen receptor genes and T-cell recognition. Nature 1988; 334:395-402.
-
(1988)
Nature
, vol.334
, pp. 395-402
-
-
Davis, M.M.1
Bjorkman, P.J.2
-
6
-
-
79955022207
-
A mechanism for TCR sharing between T cell subsets and individuals revealed by pyrosequencing
-
Venturi V, Quigley MF, Greenaway HY et al. A mechanism for TCR sharing between T cell subsets and individuals revealed by pyrosequencing. J Immunol 2011; 186:4285-94.
-
(2011)
J Immunol
, vol.186
, pp. 4285-4294
-
-
Venturi, V.1
Quigley, M.F.2
Greenaway, H.Y.3
-
7
-
-
84855479452
-
Determinants of public T cell responses
-
Li H, Ye C, Ji G, Han J. Determinants of public T cell responses. Cell Res 2012; 22:33-42.
-
(2012)
Cell Res
, vol.22
, pp. 33-42
-
-
Li, H.1
Ye, C.2
Ji, G.3
Han, J.4
-
8
-
-
0022377731
-
The involution of the ageing human thymic epithelium is independent of puberty. A morphometric study
-
Steinmann GG, Klaus B, Muller-Hermelink HK. The involution of the ageing human thymic epithelium is independent of puberty. A morphometric study. Scand J Immunol 1985; 22:563-75.
-
(1985)
Scand J Immunol
, vol.22
, pp. 563-575
-
-
Steinmann, G.G.1
Klaus, B.2
Muller-Hermelink, H.K.3
-
9
-
-
70449721165
-
Quantifying thymic export: combining models of naive T cell proliferation and TCR excision circle dynamics gives an explicit measure of thymic output
-
Bains I, Thiebaut R, Yates AJ, Callard R. Quantifying thymic export: combining models of naive T cell proliferation and TCR excision circle dynamics gives an explicit measure of thymic output. J Immunol 2009; 183:4329-36.
-
(2009)
J Immunol
, vol.183
, pp. 4329-4336
-
-
Bains, I.1
Thiebaut, R.2
Yates, A.J.3
Callard, R.4
-
10
-
-
0037018098
-
Estimating the precursor frequency of naive antigen-specific CD8 T cells
-
Blattman JN, Antia R, Sourdive DJ, Wang X, Kaech SM, Murali-Krishna K, Altman JD, Ahmed R. Estimating the precursor frequency of naive antigen-specific CD8 T cells. J Exp Med 2002; 195:657-64.
-
(2002)
J Exp Med
, vol.195
, pp. 657-664
-
-
Blattman, J.N.1
Antia, R.2
Sourdive, D.J.3
Wang, X.4
Kaech, S.M.5
Murali-Krishna, K.6
Altman, J.D.7
Ahmed, R.8
-
14
-
-
0030873556
-
Differential requirements for survival and proliferation of CD8 naïve or memory T cells
-
Tanchot C, Lemonnier FA, Pérarnau B, Freitas AA, Rocha B. Differential requirements for survival and proliferation of CD8 naïve or memory T cells. Science 1997; 276:2057-62.
-
(1997)
Science
, vol.276
, pp. 2057-2062
-
-
Tanchot, C.1
Lemonnier, F.A.2
Pérarnau, B.3
Freitas, A.A.4
Rocha, B.5
-
16
-
-
0034080178
-
Population biology of lymphocytes: the flight for survival
-
Freitas AA, Rocha B. Population biology of lymphocytes: the flight for survival. Annu Rev Immunol 2000; 18:83-111.
-
(2000)
Annu Rev Immunol
, vol.18
, pp. 83-111
-
-
Freitas, A.A.1
Rocha, B.2
-
17
-
-
58149337062
-
Memory CD8 T-cell compartment grows in size with immunological experience
-
Vezys V, Yates A, Casey KA, Lanier G, Ahmed R, Antia R, Masopust D. Memory CD8 T-cell compartment grows in size with immunological experience. Nature 2009; 457:196-9.
-
(2009)
Nature
, vol.457
, pp. 196-199
-
-
Vezys, V.1
Yates, A.2
Casey, K.A.3
Lanier, G.4
Ahmed, R.5
Antia, R.6
Masopust, D.7
-
18
-
-
0027381336
-
Lymphocyte subsets and natural killer cell activity in healthy old people and centenarians
-
Sansoni P, Cossarizza A, Brianti V et al. Lymphocyte subsets and natural killer cell activity in healthy old people and centenarians. Blood 1993; 82:2767-73.
-
(1993)
Blood
, vol.82
, pp. 2767-2773
-
-
Sansoni, P.1
Cossarizza, A.2
Brianti, V.3
-
20
-
-
84863565430
-
Homeostatic maintenance of T cells and natural killer cells
-
Boyman O, Krieg C, Homann D, Sprent J. Homeostatic maintenance of T cells and natural killer cells. Cell Mol Life Sci 2012; 69:1597-608.
-
(2012)
Cell Mol Life Sci
, vol.69
, pp. 1597-1608
-
-
Boyman, O.1
Krieg, C.2
Homann, D.3
Sprent, J.4
-
21
-
-
72949100401
-
Naive T cell homeostasis: from awareness of space to a sense of place
-
Takada K, Jameson SC. Naive T cell homeostasis: from awareness of space to a sense of place. Nat Rev Immunol 2009; 9:823-32.
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 823-832
-
-
Takada, K.1
Jameson, S.C.2
-
22
-
-
0037124341
-
Interleukin 15 is required for proliferative renewal of virus-specific memory CD8 T cells
-
Becker TC, Wherry EJ, Boone D, Murali-Krishna K, Antia R, Ma A, Ahmed R. Interleukin 15 is required for proliferative renewal of virus-specific memory CD8 T cells. J Exp Med 2002; 195:1541-8.
-
(2002)
J Exp Med
, vol.195
, pp. 1541-1548
-
-
Becker, T.C.1
Wherry, E.J.2
Boone, D.3
Murali-Krishna, K.4
Antia, R.5
Ma, A.6
Ahmed, R.7
-
23
-
-
78649804169
-
Homeostatic turnover of virus-specific memory CD8 T cells occurs stochastically and is independent of CD4 T cell help
-
Choo DK, Murali-Krishna K, Antia R, Ahmed R. Homeostatic turnover of virus-specific memory CD8 T cells occurs stochastically and is independent of CD4 T cell help. J Immunol 2010; 185:3436-44.
-
(2010)
J Immunol
, vol.185
, pp. 3436-3444
-
-
Choo, D.K.1
Murali-Krishna, K.2
Antia, R.3
Ahmed, R.4
-
24
-
-
0032720640
-
Persistence of memory CD8 T cells in MHC class I-deficient mice
-
Murali-Krishna K, Lau LL, Sambhara S, Lemonnier F, Altman J, Ahmed R. Persistence of memory CD8 T cells in MHC class I-deficient mice. Science 1999; 286:1377-81.
-
(1999)
Science
, vol.286
, pp. 1377-1381
-
-
Murali-Krishna, K.1
Lau, L.L.2
Sambhara, S.3
Lemonnier, F.4
Altman, J.5
Ahmed, R.6
-
25
-
-
0026443849
-
Adaptive cellular interactions in the immune system: the tunable activation threshold and the significance of subthreshold responses
-
Grossman Z, Paul WE. Adaptive cellular interactions in the immune system: the tunable activation threshold and the significance of subthreshold responses. Proc Natl Acad Sci U S A 1992; 89:10365-9.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 10365-10369
-
-
Grossman, Z.1
Paul, W.E.2
-
27
-
-
60549106099
-
Clonal expansions and loss of receptor diversity in the naive CD8 T cell repertoire of aged mice
-
Ahmed M, Lanzer KG, Yager EJ, Adams PS, Johnson LL, Blackman MA. Clonal expansions and loss of receptor diversity in the naive CD8 T cell repertoire of aged mice. J Immunol 2009; 182:784-92.
-
(2009)
J Immunol
, vol.182
, pp. 784-792
-
-
Ahmed, M.1
Lanzer, K.G.2
Yager, E.J.3
Adams, P.S.4
Johnson, L.L.5
Blackman, M.A.6
-
28
-
-
79951821255
-
+ TCR repertoire across the life span: evidence for clonal homogenization of the old TCR repertoire
-
+ TCR repertoire across the life span: evidence for clonal homogenization of the old TCR repertoire. J Immunol 2011; 186:2056-64.
-
(2011)
J Immunol
, vol.186
, pp. 2056-2064
-
-
Rudd, B.D.1
Venturi, V.2
Davenport, M.P.3
Nikolich-Zugich, J.4
-
29
-
-
80051970221
-
+ T-cell pool with aging governed by T-cell receptor:pMHC interactions
-
+ T-cell pool with aging governed by T-cell receptor:pMHC interactions. Proc Natl Acad Sci U S A 2011; 108:13694-9.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 13694-13699
-
-
Rudd, B.D.1
Venturi, V.2
Li, G.3
Samadder, P.4
Ertelt, J.M.5
Way, S.S.6
Davenport, M.P.7
Nikolich-Zugich, J.8
-
30
-
-
38049174331
-
Dramatic increase in naive T cell turnover is linked to loss of naive T cells from old primates
-
Cicin-Šain L, Messaoudi I, Park B et al. Dramatic increase in naive T cell turnover is linked to loss of naive T cells from old primates. Proc Natl Acad Sci U S A 2007; 104:19960-5.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 19960-19965
-
-
Cicin-Šain, L.1
Messaoudi, I.2
Park, B.3
-
31
-
-
21044451726
-
The influence of age on T cell generation and TCR diversity
-
Naylor K, Li G, Vallejo AN et al. The influence of age on T cell generation and TCR diversity. J Immunol 2005; 174:7446-52.
-
(2005)
J Immunol
, vol.174
, pp. 7446-7452
-
-
Naylor, K.1
Li, G.2
Vallejo, A.N.3
-
33
-
-
0029984776
-
Reduction of otherwise remarkably stable virus-specific cytotoxic T lymphocyte memory by heterologous viral infections
-
Selin LK, Vergilis K, Welsh RM, Nahill SR. Reduction of otherwise remarkably stable virus-specific cytotoxic T lymphocyte memory by heterologous viral infections. J Exp Med 1996; 183:2489-99.
-
(1996)
J Exp Med
, vol.183
, pp. 2489-2499
-
-
Selin, L.K.1
Vergilis, K.2
Welsh, R.M.3
Nahill, S.R.4
-
34
-
-
9244265523
-
Age-related CD8 T cell clonal expansions constrict CD8 T cell repertoire and have the potential to impair immune defense
-
Messaoudi I, Lemaoult J, Guevara-Patino JA, Metzner BM, Nikolich-Zugich J. Age-related CD8 T cell clonal expansions constrict CD8 T cell repertoire and have the potential to impair immune defense. J Exp Med 2004; 200:1347-58.
-
(2004)
J Exp Med
, vol.200
, pp. 1347-1358
-
-
Messaoudi, I.1
Lemaoult, J.2
Guevara-Patino, J.A.3
Metzner, B.M.4
Nikolich-Zugich, J.5
-
36
-
-
76549107658
-
Effect of ageing on CMV-specific CD8 T cells from CMV seropositive healthy donors
-
Pita-Lopez ML, Gayoso I, DelaRosa O, Casado JG, Alonso C, Muñoz-Gomariz E, Tarazona R, Solana R. Effect of ageing on CMV-specific CD8 T cells from CMV seropositive healthy donors. Immun Ageing 2009; 6:11.
-
(2009)
Immun Ageing
, vol.6
, pp. 11
-
-
Pita-Lopez, M.L.1
Gayoso, I.2
DelaRosa, O.3
Casado, J.G.4
Alonso, C.5
Muñoz-Gomariz, E.6
Tarazona, R.7
Solana, R.8
-
37
-
-
14744281718
-
+ T-cell repertoire, which may be the basis for an imbalance in the cytokine production profile in elderly persons
-
+ T-cell repertoire, which may be the basis for an imbalance in the cytokine production profile in elderly persons. J Virol 2005; 79:3675-83.
-
(2005)
J Virol
, vol.79
, pp. 3675-3683
-
-
Almanzar, G.1
Schwaiger, S.2
Jenewein, B.3
Keller, M.4
Herndler-Brandstetter, D.5
Würzner, R.6
Schönitzer, D.7
Grubeck-Loebenstein, B.8
-
39
-
-
84868199335
-
Age-related changes in CD8 T cell homeostasis and immunity to infection
-
Nikolich-Žugich J, Li G, Uhrlaub JL, Renkema KR, Smithey MJ. Age-related changes in CD8 T cell homeostasis and immunity to infection. Semin Immunol 2012; 24:356-64.
-
(2012)
Semin Immunol
, vol.24
, pp. 356-364
-
-
Nikolich-Žugich, J.1
Li, G.2
Uhrlaub, J.L.3
Renkema, K.R.4
Smithey, M.J.5
-
40
-
-
84871835297
-
Peripheral selection rather than thymic involution explains sudden contraction in naive CD4 T-cell diversity with age
-
Johnson PLF, Yates AJ, Goronzy JJ, Antia R. Peripheral selection rather than thymic involution explains sudden contraction in naive CD4 T-cell diversity with age. Proc Natl Acad Sci U S A 2012; 109:21432-7.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 21432-21437
-
-
Johnson, P.L.F.1
Yates, A.J.2
Goronzy, J.J.3
Antia, R.4
-
41
-
-
46249132015
-
Ageing and life-long maintenance of T-cell subsets in the face of latent persistent infections
-
Nikolich-Žugich J. Ageing and life-long maintenance of T-cell subsets in the face of latent persistent infections. Nat Rev Immunol 2008; 8:512-22.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 512-522
-
-
Nikolich-Žugich, J.1
-
42
-
-
84869776196
-
Lifelong persistent viral infection alters the naive T cell pool, impairing CD8 T cell immunity in late life
-
Smithey MJ, Li G, Venturi V, Davenport MP, Nikolich-Žugich J. Lifelong persistent viral infection alters the naive T cell pool, impairing CD8 T cell immunity in late life. J Immunol 2012; 189:5356-66.
-
(2012)
J Immunol
, vol.189
, pp. 5356-5366
-
-
Smithey, M.J.1
Li, G.2
Venturi, V.3
Davenport, M.P.4
Nikolich-Žugich, J.5
-
43
-
-
84965187257
-
The age distribution of cancer and a multi-stage theory of carcinogenesis
-
Armitage P, Doll R. The age distribution of cancer and a multi-stage theory of carcinogenesis. Br J Cancer 1954; 8:1-12.
-
(1954)
Br J Cancer
, vol.8
, pp. 1-12
-
-
Armitage, P.1
Doll, R.2
-
44
-
-
0019467329
-
Mutation and cancer: a model for human carcinogenesis
-
Moolgavkar SH, Knudson AG Jr. Mutation and cancer: a model for human carcinogenesis. J Natl Cancer Inst 1981; 66:1037-52.
-
(1981)
J Natl Cancer Inst
, vol.66
, pp. 1037-1052
-
-
Moolgavkar, S.H.1
Knudson Jr., A.G.2
-
47
-
-
33947730608
-
Asymmetric T lymphocyte division in the initiation of adaptive immune responses
-
Chang JT, Palanivel VR, Kinjyo I et al. Asymmetric T lymphocyte division in the initiation of adaptive immune responses. Science 2007; 315:1687-91.
-
(2007)
Science
, vol.315
, pp. 1687-1691
-
-
Chang, J.T.1
Palanivel, V.R.2
Kinjyo, I.3
-
48
-
-
70349648171
-
Profiling the T-cell receptor β-chain repertoire by massively parallel sequencing
-
Freeman JD, Warren RL, Webb JR, Nelson BH, Holt RA. Profiling the T-cell receptor β-chain repertoire by massively parallel sequencing. Genome Res 2009; 19:1817-24.
-
(2009)
Genome Res
, vol.19
, pp. 1817-1824
-
-
Freeman, J.D.1
Warren, R.L.2
Webb, J.R.3
Nelson, B.H.4
Holt, R.A.5
-
49
-
-
76549090763
-
High throughput sequencing reveals a complex pattern of dynamic interrelationships among human T cell subsets
-
Wang C, Sanders CM, Yang Q et al. High throughput sequencing reveals a complex pattern of dynamic interrelationships among human T cell subsets. Proc Natl Acad Sci U S A 2010; 107:1518-23.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 1518-1523
-
-
Wang, C.1
Sanders, C.M.2
Yang, Q.3
-
50
-
-
33344464667
-
Measurement of diversity
-
Simpson EH. Measurement of diversity. Nature 1949; 163:688.
-
(1949)
Nature
, vol.163
, pp. 688
-
-
Simpson, E.H.1
-
51
-
-
84873605796
-
High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire
-
DeKosky BJ, Ippolito GC, Deschner RP et al. High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire. Nat Biotechnol 2013; 31:166-9.
-
(2013)
Nat Biotechnol
, vol.31
, pp. 166-169
-
-
DeKosky, B.J.1
Ippolito, G.C.2
Deschner, R.P.3
-
52
-
-
0000803388
-
The population frequencies of species and the estimation of population parameters
-
Good IJ. The population frequencies of species and the estimation of population parameters. Biometrika 1953; 40:237-64.
-
(1953)
Biometrika
, vol.40
, pp. 237-264
-
-
Good, I.J.1
-
53
-
-
84875700725
-
Predicting the molecular complexity of sequencing libraries
-
Daley T, Smith AD. Predicting the molecular complexity of sequencing libraries. Nat Methods 2013; 10:325-7.
-
(2013)
Nat Methods
, vol.10
, pp. 325-327
-
-
Daley, T.1
Smith, A.D.2
-
54
-
-
84857416171
-
Maintenance of peripheral naive T cells is sustained by thymus output in mice but not humans
-
den Braber I, Mugwagwa T, Vrisekoop N et al. Maintenance of peripheral naive T cells is sustained by thymus output in mice but not humans. Immunity 2012; 36:288-97.
-
(2012)
Immunity
, vol.36
, pp. 288-297
-
-
den Braber, I.1
Mugwagwa, T.2
Vrisekoop, N.3
-
56
-
-
0036199994
-
Kinetics of B, CD4 T, and CD8 T cells infused into humans: estimates of intravascular:extravascular ratios and total body counts
-
Storek J, Lalovic BB, Rupert K, Dawson MA, Shen DD, Maloney DG. Kinetics of B, CD4 T, and CD8 T cells infused into humans: estimates of intravascular:extravascular ratios and total body counts. Clin Immunol 2002; 102:249-57.
-
(2002)
Clin Immunol
, vol.102
, pp. 249-257
-
-
Storek, J.1
Lalovic, B.B.2
Rupert, K.3
Dawson, M.A.4
Shen, D.D.5
Maloney, D.G.6
-
57
-
-
20844437643
-
+ T cells constrains the TCR repertoire in healthy human adults
-
+ T cells constrains the TCR repertoire in healthy human adults. Eur J Immunol 2005; 35:1987-94.
-
(2005)
Eur J Immunol
, vol.35
, pp. 1987-1994
-
-
Kohler, S.1
Wagner, U.2
Pierer, M.3
-
59
-
-
67649396090
-
Thymic involution and immune reconstitution
-
Lynch HE, Goldberg GL, Chidgey A, Van den Brink MR, Boyd R, Sempowski GD. Thymic involution and immune reconstitution. Trends Immunol 2009; 30:366-73.
-
(2009)
Trends Immunol
, vol.30
, pp. 366-373
-
-
Lynch, H.E.1
Goldberg, G.L.2
Chidgey, A.3
Van den Brink, M.R.4
Boyd, R.5
Sempowski, G.D.6
-
61
-
-
32044433093
-
Longitudinal studies of clonally expanded CD8 T cells reveal a repertoire shrinkage predicting mortality and an increased number of dysfunctional cytomegalovirus-specific T cells in the very elderly
-
Hadrup SR, Strindhall J, Køllgaard T, Seremet T, Johansson B, Pawelec G, thor Straten P, Wikby A. Longitudinal studies of clonally expanded CD8 T cells reveal a repertoire shrinkage predicting mortality and an increased number of dysfunctional cytomegalovirus-specific T cells in the very elderly. J Immunol 2006; 176:2645-53.
-
(2006)
J Immunol
, vol.176
, pp. 2645-2653
-
-
Hadrup, S.R.1
Strindhall, J.2
Køllgaard, T.3
Seremet, T.4
Johansson, B.5
Pawelec, G.6
thor Straten, P.7
Wikby, A.8
|