메뉴 건너뛰기




Volumn 33, Issue 2, 2012, Pages 84-90

Memory T cell inflation: Understanding cause and effect

Author keywords

Cytomegalovirus; Memory cells; T cells; Viral infections

Indexed keywords

CD27 ANTIGEN; CD28 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 7 RECEPTOR; L SELECTIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; SIMIAN IMMUNODEFICIENCY VIRUS VACCINE;

EID: 84856548651     PISSN: 14714906     EISSN: 14714981     Source Type: Journal    
DOI: 10.1016/j.it.2011.11.005     Document Type: Review
Times cited : (115)

References (79)
  • 1
    • 77954170594 scopus 로고    scopus 로고
    • Review of cytomegalovirus seroprevalence and demographic characteristics associated with infection
    • Cannon M.J., et al. Review of cytomegalovirus seroprevalence and demographic characteristics associated with infection. Rev. Med. Virol. 2010, 20:202-213.
    • (2010) Rev. Med. Virol. , vol.20 , pp. 202-213
    • Cannon, M.J.1
  • 2
    • 33751118475 scopus 로고    scopus 로고
    • Generation and maintenance of human memory cells during viral infection
    • Halwani R., et al. Generation and maintenance of human memory cells during viral infection. Springer Semin. Immunopathol. 2006, 28:197-208.
    • (2006) Springer Semin. Immunopathol. , vol.28 , pp. 197-208
    • Halwani, R.1
  • 3
    • 24344489044 scopus 로고    scopus 로고
    • Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects
    • Sylwester A.W., et al. Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects. J. Exp. Med. 2005, 202:673-685.
    • (2005) J. Exp. Med. , vol.202 , pp. 673-685
    • Sylwester, A.W.1
  • 4
    • 0141539465 scopus 로고    scopus 로고
    • Population analysis of antiviral T cell responses using MHC class I-peptide tetramers
    • Komatsu H., et al. Population analysis of antiviral T cell responses using MHC class I-peptide tetramers. Clin. Exp. Immunol. 2003, 134:9-12.
    • (2003) Clin. Exp. Immunol. , vol.134 , pp. 9-12
    • Komatsu, H.1
  • 5
    • 0034468083 scopus 로고    scopus 로고
    • Enrichment of immediate-early 1 (m123/pp89) peptide-specific CD8 T cells in a pulmonary CD62L(lo) memory-effector cell pool during latent murine cytomegalovirus infection of the lungs
    • Holtappels R., et al. Enrichment of immediate-early 1 (m123/pp89) peptide-specific CD8 T cells in a pulmonary CD62L(lo) memory-effector cell pool during latent murine cytomegalovirus infection of the lungs. J. Virol. 2000, 74:11495-11503.
    • (2000) J. Virol. , vol.74 , pp. 11495-11503
    • Holtappels, R.1
  • 6
    • 0037442113 scopus 로고    scopus 로고
    • Memory inflation: continuous accumulation of antiviral CD8+ T cells over time
    • Karrer U., et al. Memory inflation: continuous accumulation of antiviral CD8+ T cells over time. J. Immunol. 2003, 170:2022-2029.
    • (2003) J. Immunol. , vol.170 , pp. 2022-2029
    • Karrer, U.1
  • 7
    • 33745293908 scopus 로고    scopus 로고
    • Four distinct patterns of memory CD8 T cell responses to chronic murine cytomegalovirus infection
    • Munks M.W., et al. Four distinct patterns of memory CD8 T cell responses to chronic murine cytomegalovirus infection. J. Immunol. 2006, 177:450-458.
    • (2006) J. Immunol. , vol.177 , pp. 450-458
    • Munks, M.W.1
  • 8
    • 17444366583 scopus 로고    scopus 로고
    • Evolution of diverse antiviral CD8+ T cell populations after murine cytomegalovirus infection
    • Sierro S., et al. Evolution of diverse antiviral CD8+ T cell populations after murine cytomegalovirus infection. Eur. J. Immunol. 2005, 35:1113-1123.
    • (2005) Eur. J. Immunol. , vol.35 , pp. 1113-1123
    • Sierro, S.1
  • 9
    • 53549106627 scopus 로고    scopus 로고
    • Memory inflation during chronic viral infection is maintained by continuous production of short-lived, functional T cells
    • Snyder C.M., et al. Memory inflation during chronic viral infection is maintained by continuous production of short-lived, functional T cells. Immunity 2008, 29:650-659.
    • (2008) Immunity , vol.29 , pp. 650-659
    • Snyder, C.M.1
  • 10
    • 2442418917 scopus 로고    scopus 로고
    • The size and phenotype of virus-specific T cell populations is determined by repetitive antigenic stimulation and environmental cytokines
    • Gamadia L.E., et al. The size and phenotype of virus-specific T cell populations is determined by repetitive antigenic stimulation and environmental cytokines. J. Immunol. 2004, 172:6107-6114.
    • (2004) J. Immunol. , vol.172 , pp. 6107-6114
    • Gamadia, L.E.1
  • 11
    • 80051920889 scopus 로고    scopus 로고
    • Cytomegalovirus-specific T cell immunity is maintained in immunosenescent rhesus macaques
    • Cicin-Sain L., et al. Cytomegalovirus-specific T cell immunity is maintained in immunosenescent rhesus macaques. J. Immunol. 2011, 187:1722-1732.
    • (2011) J. Immunol. , vol.187 , pp. 1722-1732
    • Cicin-Sain, L.1
  • 12
    • 42249099167 scopus 로고    scopus 로고
    • Dynamics of T cell memory in human cytomegalovirus infection
    • Waller E.C., et al. Dynamics of T cell memory in human cytomegalovirus infection. Med. Microbiol. Immunol. 2008, 197:83-96.
    • (2008) Med. Microbiol. Immunol. , vol.197 , pp. 83-96
    • Waller, E.C.1
  • 13
    • 0037825764 scopus 로고    scopus 로고
    • Large numbers of dysfunctional CD8+ T lymphocytes bearing receptors for a single dominant CMV epitope in the very old
    • Ouyang Q., et al. Large numbers of dysfunctional CD8+ T lymphocytes bearing receptors for a single dominant CMV epitope in the very old. J. Clin. Immunol. 2003, 23:247-257.
    • (2003) J. Clin. Immunol. , vol.23 , pp. 247-257
    • Ouyang, Q.1
  • 14
    • 45549091431 scopus 로고    scopus 로고
    • Cutting edge: murine cytomegalovirus induces a polyfunctional CD4 T cell response
    • Arens R., et al. Cutting edge: murine cytomegalovirus induces a polyfunctional CD4 T cell response. J. Immunol. 2008, 180:6472-6476.
    • (2008) J. Immunol. , vol.180 , pp. 6472-6476
    • Arens, R.1
  • 15
    • 33748947326 scopus 로고    scopus 로고
    • PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression
    • Day C.L., et al. PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression. Nature 2006, 443:350-354.
    • (2006) Nature , vol.443 , pp. 350-354
    • Day, C.L.1
  • 16
    • 78049414864 scopus 로고    scopus 로고
    • Molecular profiling of cytomegalovirus-induced human CD8+ T cell differentiation
    • Hertoghs K.M., et al. Molecular profiling of cytomegalovirus-induced human CD8+ T cell differentiation. J. Clin. Invest. 2010, 120:4077-4090.
    • (2010) J. Clin. Invest. , vol.120 , pp. 4077-4090
    • Hertoghs, K.M.1
  • 17
    • 76249117986 scopus 로고    scopus 로고
    • Inflation and long-term maintenance of CD8 T cells responding to a latent herpesvirus depend upon establishment of latency and presence of viral antigens
    • Lang A., et al. Inflation and long-term maintenance of CD8 T cells responding to a latent herpesvirus depend upon establishment of latency and presence of viral antigens. J. Immunol. 2009, 183:8077-8087.
    • (2009) J. Immunol. , vol.183 , pp. 8077-8087
    • Lang, A.1
  • 18
    • 24944509220 scopus 로고    scopus 로고
    • T cells and viral persistence: lessons from diverse infections
    • Klenerman P., Hill A. T cells and viral persistence: lessons from diverse infections. Nat. Immunol. 2005, 6:873-879.
    • (2005) Nat. Immunol. , vol.6 , pp. 873-879
    • Klenerman, P.1    Hill, A.2
  • 19
    • 33644833785 scopus 로고    scopus 로고
    • Genome-wide analysis reveals a highly diverse CD8 T cell response to murine cytomegalovirus
    • Munks M.W., et al. Genome-wide analysis reveals a highly diverse CD8 T cell response to murine cytomegalovirus. J. Immunol. 2006, 176:3760-3766.
    • (2006) J. Immunol. , vol.176 , pp. 3760-3766
    • Munks, M.W.1
  • 20
    • 80055065257 scopus 로고    scopus 로고
    • Sustained CD8+ T cell memory inflation after infection with a single-cycle cytomegalovirus
    • Snyder C.M., et al. Sustained CD8+ T cell memory inflation after infection with a single-cycle cytomegalovirus. PLoS Pathog. 2011, 7:e1002295.
    • (2011) PLoS Pathog. , vol.7
    • Snyder, C.M.1
  • 21
    • 79851488412 scopus 로고    scopus 로고
    • A dominant role for the immunoproteasome in CD8+ T cell responses to murine cytomegalovirus
    • Hutchinson S., et al. A dominant role for the immunoproteasome in CD8+ T cell responses to murine cytomegalovirus. PLoS ONE 2011, 6:e14646.
    • (2011) PLoS ONE , vol.6
    • Hutchinson, S.1
  • 22
    • 42249089348 scopus 로고    scopus 로고
    • The salivary glands as a privileged site of cytomegalovirus immune evasion and persistence
    • Campbell A.E., et al. The salivary glands as a privileged site of cytomegalovirus immune evasion and persistence. Med. Microbiol. Immunol. 2008, 197:205-213.
    • (2008) Med. Microbiol. Immunol. , vol.197 , pp. 205-213
    • Campbell, A.E.1
  • 23
    • 0242569404 scopus 로고    scopus 로고
    • Pathogenesis of murine cytomegalovirus infection
    • Krmpotic A., et al. Pathogenesis of murine cytomegalovirus infection. Microbes Infect. 2003, 5:1263-1277.
    • (2003) Microbes Infect. , vol.5 , pp. 1263-1277
    • Krmpotic, A.1
  • 24
    • 80051740355 scopus 로고    scopus 로고
    • Dissecting the requirements for maintenance of the CMV-specific memory T-cell pool
    • Loewendorf A.I., et al. Dissecting the requirements for maintenance of the CMV-specific memory T-cell pool. Viral Immunol. 2011, 24:351-355.
    • (2011) Viral Immunol. , vol.24 , pp. 351-355
    • Loewendorf, A.I.1
  • 25
    • 0035126615 scopus 로고    scopus 로고
    • Random, asynchronous, and asymmetric transcriptional activity of enhancer-flanking major immediate-early genes ie1/3 and ie2 during murine cytomegalovirus latency in the lungs
    • Grzimek N.K., et al. Random, asynchronous, and asymmetric transcriptional activity of enhancer-flanking major immediate-early genes ie1/3 and ie2 during murine cytomegalovirus latency in the lungs. J. Virol. 2001, 75:2692-2705.
    • (2001) J. Virol. , vol.75 , pp. 2692-2705
    • Grzimek, N.K.1
  • 26
    • 0032889311 scopus 로고    scopus 로고
    • Focal transcriptional activity of murine cytomegalovirus during latency in the lungs
    • Kurz S.K., et al. Focal transcriptional activity of murine cytomegalovirus during latency in the lungs. J. Virol. 1999, 73:482-494.
    • (1999) J. Virol. , vol.73 , pp. 482-494
    • Kurz, S.K.1
  • 27
    • 33750348127 scopus 로고    scopus 로고
    • CD8 T cells control cytomegalovirus latency by epitope-specific sensing of transcriptional reactivation
    • Simon C.O., et al. CD8 T cells control cytomegalovirus latency by epitope-specific sensing of transcriptional reactivation. J. Virol. 2006, 80:10436-10456.
    • (2006) J. Virol. , vol.80 , pp. 10436-10456
    • Simon, C.O.1
  • 28
    • 34249788420 scopus 로고    scopus 로고
    • Viral interference with antigen presentation does not alter acute or chronic CD8 T cell immunodominance in murine cytomegalovirus infection
    • Munks M.W., et al. Viral interference with antigen presentation does not alter acute or chronic CD8 T cell immunodominance in murine cytomegalovirus infection. J. Immunol. 2007, 178:7235-7241.
    • (2007) J. Immunol. , vol.178 , pp. 7235-7241
    • Munks, M.W.1
  • 29
    • 33747803947 scopus 로고    scopus 로고
    • Coordinated function of murine cytomegalovirus genes completely inhibits CTL lysis
    • Pinto A.K., et al. Coordinated function of murine cytomegalovirus genes completely inhibits CTL lysis. J. Immunol. 2006, 177:3225-3234.
    • (2006) J. Immunol. , vol.177 , pp. 3225-3234
    • Pinto, A.K.1
  • 30
    • 77950447606 scopus 로고    scopus 로고
    • Cross-presentation of a spread-defective MCMV is sufficient to prime the majority of virus-specific CD8+ T cells
    • Snyder C.M., et al. Cross-presentation of a spread-defective MCMV is sufficient to prime the majority of virus-specific CD8+ T cells. PLoS ONE 2010, 5:e9681.
    • (2010) PLoS ONE , vol.5
    • Snyder, C.M.1
  • 31
    • 80052170950 scopus 로고    scopus 로고
    • Batf3 transcription factor-dependent DC subsets in murine CMV infection: differential impact on T-cell priming and memory inflation
    • Torti N., et al. Batf3 transcription factor-dependent DC subsets in murine CMV infection: differential impact on T-cell priming and memory inflation. Eur. J. Immunol. 2011, 41:2612-2618.
    • (2011) Eur. J. Immunol. , vol.41 , pp. 2612-2618
    • Torti, N.1
  • 32
    • 78751704362 scopus 로고    scopus 로고
    • CD169-positive macrophages dominate antitumor immunity by crosspresenting dead cell-associated antigens
    • Asano K., et al. CD169-positive macrophages dominate antitumor immunity by crosspresenting dead cell-associated antigens. Immunity 2011, 34:85-95.
    • (2011) Immunity , vol.34 , pp. 85-95
    • Asano, K.1
  • 33
    • 80051762799 scopus 로고    scopus 로고
    • Antigen-presenting cells of hematopoietic origin prime cytomegalovirus-specific CD8 T cells but are not sufficient for driving memory inflation during viral latency
    • Seckert C.K., et al. Antigen-presenting cells of hematopoietic origin prime cytomegalovirus-specific CD8 T cells but are not sufficient for driving memory inflation during viral latency. J. Gen. Virol. 2011, 92:1994-2005.
    • (2011) J. Gen. Virol. , vol.92 , pp. 1994-2005
    • Seckert, C.K.1
  • 34
    • 80055072972 scopus 로고    scopus 로고
    • Non-hematopoietic cells in lymph nodes drive memory CD8 T cell inflation during murine cytomegalovirus infection
    • Torti N., et al. Non-hematopoietic cells in lymph nodes drive memory CD8 T cell inflation during murine cytomegalovirus infection. PLoS Pathog. 2011, 7:e1002313.
    • (2011) PLoS Pathog. , vol.7
    • Torti, N.1
  • 35
    • 79953238006 scopus 로고    scopus 로고
    • Cross-dressed dendritic cells drive memory CD8+ T-cell activation after viral infection
    • Wakim L.M., Bevan M.J. Cross-dressed dendritic cells drive memory CD8+ T-cell activation after viral infection. Nature 2011, 471:629-632.
    • (2011) Nature , vol.471 , pp. 629-632
    • Wakim, L.M.1    Bevan, M.J.2
  • 36
    • 77951692771 scopus 로고    scopus 로고
    • Plasticity in programming of effector and memory CD8 T-cell formation
    • Arens R., Schoenberger S.P. Plasticity in programming of effector and memory CD8 T-cell formation. Immunol. Rev. 2010, 235:190-205.
    • (2010) Immunol. Rev. , vol.235 , pp. 190-205
    • Arens, R.1    Schoenberger, S.P.2
  • 37
    • 79954995537 scopus 로고    scopus 로고
    • Differential B7-CD28 costimulatory requirements for stable and inflationary mouse cytomegalovirus-specific memory CD8 T cell populations
    • Arens R., et al. Differential B7-CD28 costimulatory requirements for stable and inflationary mouse cytomegalovirus-specific memory CD8 T cell populations. J. Immunol. 2011, 186:3874-3881.
    • (2011) J. Immunol. , vol.186 , pp. 3874-3881
    • Arens, R.1
  • 38
    • 34848849793 scopus 로고    scopus 로고
    • OX40 costimulation promotes persistence of cytomegalovirus-specific CD8 T cells: a CD4-dependent mechanism
    • Humphreys I.R., et al. OX40 costimulation promotes persistence of cytomegalovirus-specific CD8 T cells: a CD4-dependent mechanism. J. Immunol. 2007, 179:2195-2202.
    • (2007) J. Immunol. , vol.179 , pp. 2195-2202
    • Humphreys, I.R.1
  • 39
    • 77957102912 scopus 로고    scopus 로고
    • Biphasic role of 4-1BB in the regulation of mouse cytomegalovirus-specific CD8+ T cells
    • Humphreys I.R., et al. Biphasic role of 4-1BB in the regulation of mouse cytomegalovirus-specific CD8+ T cells. Eur. J. Immunol. 2010, 40:2762-2768.
    • (2010) Eur. J. Immunol. , vol.40 , pp. 2762-2768
    • Humphreys, I.R.1
  • 40
    • 34250787647 scopus 로고    scopus 로고
    • Differential role of IL-2R signaling for CD8+ T cell responses in acute and chronic viral infections
    • Bachmann M.F., et al. Differential role of IL-2R signaling for CD8+ T cell responses in acute and chronic viral infections. Eur. J. Immunol. 2007, 37:1502-1512.
    • (2007) Eur. J. Immunol. , vol.37 , pp. 1502-1512
    • Bachmann, M.F.1
  • 41
    • 80052038585 scopus 로고    scopus 로고
    • Autocrine IL-2 is required for secondary population expansion of CD8+ memory T cells
    • Feau S., et al. Autocrine IL-2 is required for secondary population expansion of CD8+ memory T cells. Nat. Immunol. 2011, 12:908-913.
    • (2011) Nat. Immunol. , vol.12 , pp. 908-913
    • Feau, S.1
  • 42
    • 24744444751 scopus 로고    scopus 로고
    • IL-7 receptor alpha chain expression distinguishes functional subsets of virus-specific human CD8+ T cells
    • van Leeuwen E.M., et al. IL-7 receptor alpha chain expression distinguishes functional subsets of virus-specific human CD8+ T cells. Blood 2005, 106:2091-2098.
    • (2005) Blood , vol.106 , pp. 2091-2098
    • van Leeuwen, E.M.1
  • 43
    • 78649896441 scopus 로고    scopus 로고
    • IL-10 restricts memory T cell inflation during cytomegalovirus infection
    • Jones M., et al. IL-10 restricts memory T cell inflation during cytomegalovirus infection. J. Immunol. 2010, 185:3583-3592.
    • (2010) J. Immunol. , vol.185 , pp. 3583-3592
    • Jones, M.1
  • 44
    • 0024563850 scopus 로고
    • Site-restricted persistent cytomegalovirus infection after selective long-term depletion of CD4+ T lymphocytes
    • Jonjic S., et al. Site-restricted persistent cytomegalovirus infection after selective long-term depletion of CD4+ T lymphocytes. J. Exp. Med. 1989, 169:1199-1212.
    • (1989) J. Exp. Med. , vol.169 , pp. 1199-1212
    • Jonjic, S.1
  • 45
    • 78650037629 scopus 로고    scopus 로고
    • B7-mediated costimulation of CD4 T cells constrains cytomegalovirus persistence
    • Arens R., et al. B7-mediated costimulation of CD4 T cells constrains cytomegalovirus persistence. J. Virol. 2011, 85:390-396.
    • (2011) J. Virol. , vol.85 , pp. 390-396
    • Arens, R.1
  • 46
    • 80052321890 scopus 로고    scopus 로고
    • Absence of cross-presenting cells in the salivary gland and viral immune evasion confine cytomegalovirus immune control to effector CD4 T cells
    • Walton S.M., et al. Absence of cross-presenting cells in the salivary gland and viral immune evasion confine cytomegalovirus immune control to effector CD4 T cells. PLoS Pathog. 2011, 7:e1002214.
    • (2011) PLoS Pathog. , vol.7
    • Walton, S.M.1
  • 47
    • 70349320168 scopus 로고    scopus 로고
    • CD4+ T cell help has an epitope-dependent impact on CD8+ T cell memory inflation during murine cytomegalovirus infection
    • Snyder C.M., et al. CD4+ T cell help has an epitope-dependent impact on CD8+ T cell memory inflation during murine cytomegalovirus infection. J. Immunol. 2009, 183:3932-3941.
    • (2009) J. Immunol. , vol.183 , pp. 3932-3941
    • Snyder, C.M.1
  • 48
    • 79960702132 scopus 로고    scopus 로고
    • T-cell help permits memory CD8+ T-cell inflation during cytomegalovirus latency
    • Walton S.M., et al. T-cell help permits memory CD8+ T-cell inflation during cytomegalovirus latency. Eur. J. Immunol. 2011, 41:2248-2259.
    • (2011) Eur. J. Immunol. , vol.41 , pp. 2248-2259
    • Walton, S.M.1
  • 49
    • 79955009432 scopus 로고    scopus 로고
    • Management of cytomegalovirus infection in solid organ transplantation
    • Kotton C.N. Management of cytomegalovirus infection in solid organ transplantation. Nat. Rev. Nephrol. 2010, 6:711-721.
    • (2010) Nat. Rev. Nephrol. , vol.6 , pp. 711-721
    • Kotton, C.N.1
  • 50
    • 79953162644 scopus 로고    scopus 로고
    • Cytomegalovirus infections during pregnancy
    • Nigro G., Adler S.P. Cytomegalovirus infections during pregnancy. Curr. Opin. Obstet. Gynecol. 2011, 23:123-128.
    • (2011) Curr. Opin. Obstet. Gynecol. , vol.23 , pp. 123-128
    • Nigro, G.1    Adler, S.P.2
  • 51
    • 0030963722 scopus 로고    scopus 로고
    • T cell therapy of human CMV and EBV infection in immunocompromised hosts
    • Riddell S.R., Greenberg P.D. T cell therapy of human CMV and EBV infection in immunocompromised hosts. Rev. Med. Virol. 1997, 7:181-192.
    • (1997) Rev. Med. Virol. , vol.7 , pp. 181-192
    • Riddell, S.R.1    Greenberg, P.D.2
  • 52
    • 0036624737 scopus 로고    scopus 로고
    • Infusion of cytomegalovirus (CMV)-specific T cells for the treatment of CMV infection not responding to antiviral chemotherapy
    • Einsele H., et al. Infusion of cytomegalovirus (CMV)-specific T cells for the treatment of CMV infection not responding to antiviral chemotherapy. Blood 2002, 99:3916-3922.
    • (2002) Blood , vol.99 , pp. 3916-3922
    • Einsele, H.1
  • 53
    • 67649635053 scopus 로고    scopus 로고
    • Adoptive T-cell therapy of a lung transplanted patient with severe CMV disease and resistance to antiviral therapy
    • Brestrich G., et al. Adoptive T-cell therapy of a lung transplanted patient with severe CMV disease and resistance to antiviral therapy. Am. J. Transplant. 2009, 9:1679-1684.
    • (2009) Am. J. Transplant. , vol.9 , pp. 1679-1684
    • Brestrich, G.1
  • 54
    • 0032555912 scopus 로고    scopus 로고
    • Hierarchical and redundant lymphocyte subset control precludes cytomegalovirus replication during latent infection
    • Polic B., et al. Hierarchical and redundant lymphocyte subset control precludes cytomegalovirus replication during latent infection. J. Exp. Med. 1998, 188:1047-1054.
    • (1998) J. Exp. Med. , vol.188 , pp. 1047-1054
    • Polic, B.1
  • 55
    • 10744232252 scopus 로고    scopus 로고
    • Expansion of protective CD8+ T-cell responses driven by recombinant cytomegaloviruses
    • Karrer U., et al. Expansion of protective CD8+ T-cell responses driven by recombinant cytomegaloviruses. J. Virol. 2004, 78:2255-2264.
    • (2004) J. Virol. , vol.78 , pp. 2255-2264
    • Karrer, U.1
  • 56
    • 61949216736 scopus 로고    scopus 로고
    • Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge
    • Hansen S.G., et al. Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge. Nat. Med. 2009, 15:293-299.
    • (2009) Nat. Med. , vol.15 , pp. 293-299
    • Hansen, S.G.1
  • 57
    • 79957618772 scopus 로고    scopus 로고
    • Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine
    • Hansen S.G., et al. Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine. Nature 2011, 473:523-527.
    • (2011) Nature , vol.473 , pp. 523-527
    • Hansen, S.G.1
  • 58
    • 78649899880 scopus 로고    scopus 로고
    • Recombinant mouse cytomegalovirus expressing a ligand for the NKG2D receptor is attenuated and has improved vaccine properties
    • Slavuljica I., et al. Recombinant mouse cytomegalovirus expressing a ligand for the NKG2D receptor is attenuated and has improved vaccine properties. J. Clin. Invest. 2010, 120:4532-4545.
    • (2010) J. Clin. Invest. , vol.120 , pp. 4532-4545
    • Slavuljica, I.1
  • 59
    • 48849108250 scopus 로고    scopus 로고
    • Mechanisms of cytomegalovirus-accelerated vascular disease: induction of paracrine factors that promote angiogenesis and wound healing
    • Streblow D.N., et al. Mechanisms of cytomegalovirus-accelerated vascular disease: induction of paracrine factors that promote angiogenesis and wound healing. Curr. Top. Microbiol. Immunol. 2008, 325:397-415.
    • (2008) Curr. Top. Microbiol. Immunol. , vol.325 , pp. 397-415
    • Streblow, D.N.1
  • 60
    • 77955874092 scopus 로고    scopus 로고
    • Cytomegalovirus antibody levels, inflammation, and mortality among elderly Latinos over 9 years of follow-up
    • Roberts E.T., et al. Cytomegalovirus antibody levels, inflammation, and mortality among elderly Latinos over 9 years of follow-up. Am. J. Epidemiol. 2010, 172:363-371.
    • (2010) Am. J. Epidemiol. , vol.172 , pp. 363-371
    • Roberts, E.T.1
  • 61
    • 0016256736 scopus 로고
    • Ageing, immune response, and mortality
    • Roberts-Thomson I.C., et al. Ageing, immune response, and mortality. Lancet 1974, 2:368-370.
    • (1974) Lancet , vol.2 , pp. 368-370
    • Roberts-Thomson, I.C.1
  • 62
    • 0023639417 scopus 로고
    • Decline in mitogen induced proliferation of lymphocytes with increasing age
    • Murasko D.M., et al. Decline in mitogen induced proliferation of lymphocytes with increasing age. Clin. Exp. Immunol. 1987, 70:440-448.
    • (1987) Clin. Exp. Immunol. , vol.70 , pp. 440-448
    • Murasko, D.M.1
  • 63
    • 0037396188 scopus 로고    scopus 로고
    • Morbidity does not influence the T-cell immune risk phenotype in the elderly: findings in the Swedish NONA Immune Study using sample selection protocols
    • Nilsson B.O., et al. Morbidity does not influence the T-cell immune risk phenotype in the elderly: findings in the Swedish NONA Immune Study using sample selection protocols. Mech. Ageing Dev. 2003, 124:469-476.
    • (2003) Mech. Ageing Dev. , vol.124 , pp. 469-476
    • Nilsson, B.O.1
  • 64
    • 0032524932 scopus 로고    scopus 로고
    • Changes in CD8 and CD4 lymphocyte subsets, T cell proliferation responses and non-survival in the very old: the Swedish longitudinal OCTO-immune study
    • Wikby A., et al. Changes in CD8 and CD4 lymphocyte subsets, T cell proliferation responses and non-survival in the very old: the Swedish longitudinal OCTO-immune study. Mech. Ageing Dev. 1998, 102:187-198.
    • (1998) Mech. Ageing Dev. , vol.102 , pp. 187-198
    • Wikby, A.1
  • 65
    • 0035915757 scopus 로고    scopus 로고
    • Age-related change in peripheral blood T-lymphocyte subpopulations and cytomegalovirus infection in the very old: the Swedish longitudinal OCTO immune study
    • Olsson J., et al. Age-related change in peripheral blood T-lymphocyte subpopulations and cytomegalovirus infection in the very old: the Swedish longitudinal OCTO immune study. Mech. Ageing Dev. 2000, 121:187-201.
    • (2000) Mech. Ageing Dev. , vol.121 , pp. 187-201
    • Olsson, J.1
  • 66
    • 59249090000 scopus 로고    scopus 로고
    • Cytomegalovirus-seropositivity has a profound influence on the magnitude of major lymphoid subsets within healthy individuals
    • Chidrawar S., et al. Cytomegalovirus-seropositivity has a profound influence on the magnitude of major lymphoid subsets within healthy individuals. Clin. Exp. Immunol. 2009, 155:423-432.
    • (2009) Clin. Exp. Immunol. , vol.155 , pp. 423-432
    • Chidrawar, S.1
  • 67
    • 0242317690 scopus 로고    scopus 로고
    • Association between cytomegalovirus infection, enhanced proinflammatory response and low level of anti-hemagglutinins during the anti-influenza vaccination-an impact of immunosenescence
    • Trzonkowski P., et al. Association between cytomegalovirus infection, enhanced proinflammatory response and low level of anti-hemagglutinins during the anti-influenza vaccination-an impact of immunosenescence. Vaccine 2003, 21:3826-3836.
    • (2003) Vaccine , vol.21 , pp. 3826-3836
    • Trzonkowski, P.1
  • 68
    • 79960631102 scopus 로고    scopus 로고
    • Cytomegalovirus infection and responsiveness to influenza vaccination in elderly residents of long-term care facilities
    • den Elzen W.P., et al. Cytomegalovirus infection and responsiveness to influenza vaccination in elderly residents of long-term care facilities. Vaccine 2011, 29:4869-4874.
    • (2011) Vaccine , vol.29 , pp. 4869-4874
    • den Elzen, W.P.1
  • 69
    • 10344257508 scopus 로고    scopus 로고
    • Herpesvirus-specific CD8 T cell immunity in old age: cytomegalovirus impairs the response to a coresident EBV infection
    • Khan N., et al. Herpesvirus-specific CD8 T cell immunity in old age: cytomegalovirus impairs the response to a coresident EBV infection. J. Immunol. 2004, 173:7481-7489.
    • (2004) J. Immunol. , vol.173 , pp. 7481-7489
    • Khan, N.1
  • 70
    • 33749513413 scopus 로고    scopus 로고
    • Differential usage of cellular niches by cytomegalovirus versus EBV- and influenza virus-specific CD8+ T cells
    • van Leeuwen E.M., et al. Differential usage of cellular niches by cytomegalovirus versus EBV- and influenza virus-specific CD8+ T cells. J. Immunol. 2006, 177:4998-5005.
    • (2006) J. Immunol. , vol.177 , pp. 4998-5005
    • van Leeuwen, E.M.1
  • 71
    • 58149337062 scopus 로고    scopus 로고
    • Memory CD8 T-cell compartment grows in size with immunological experience
    • Vezys V., et al. Memory CD8 T-cell compartment grows in size with immunological experience. Nature 2009, 457:196-199.
    • (2009) Nature , vol.457 , pp. 196-199
    • Vezys, V.1
  • 72
    • 80053516103 scopus 로고    scopus 로고
    • Functional CD8 T cell memory responding to persistent latent infection is maintained for life
    • Lang A., Nikolich-Zugich J. Functional CD8 T cell memory responding to persistent latent infection is maintained for life. J. Immunol. 2011, 187:3759-3768.
    • (2011) J. Immunol. , vol.187 , pp. 3759-3768
    • Lang, A.1    Nikolich-Zugich, J.2
  • 73
    • 66949121841 scopus 로고    scopus 로고
    • Cutting edge: shift in antigen dependence by an antiviral MHC class Ib-restricted CD8 T cell response during persistent viral infection
    • Swanson P.A., et al. Cutting edge: shift in antigen dependence by an antiviral MHC class Ib-restricted CD8 T cell response during persistent viral infection. J. Immunol. 2009, 182:5198-5202.
    • (2009) J. Immunol. , vol.182 , pp. 5198-5202
    • Swanson, P.A.1
  • 74
    • 46949090374 scopus 로고    scopus 로고
    • An MHC class Ib-restricted CD8 T cell response confers antiviral immunity
    • Swanson P.A., et al. An MHC class Ib-restricted CD8 T cell response confers antiviral immunity. J. Exp. Med. 2008, 205:1647-1657.
    • (2008) J. Exp. Med. , vol.205 , pp. 1647-1657
    • Swanson, P.A.1
  • 75
    • 29644434828 scopus 로고    scopus 로고
    • Prolonged activation of virus-specific CD8+ T cells after acute B19 infection
    • Isa A., et al. Prolonged activation of virus-specific CD8+ T cells after acute B19 infection. PLoS Med. 2005, 2:e343.
    • (2005) PLoS Med. , vol.2
    • Isa, A.1
  • 76
    • 24644510660 scopus 로고    scopus 로고
    • Sustained CD8+ T-cell responses induced after acute parvovirus B19 infection in humans
    • Norbeck O., et al. Sustained CD8+ T-cell responses induced after acute parvovirus B19 infection in humans. J. Virol. 2005, 79:12117-12121.
    • (2005) J. Virol. , vol.79 , pp. 12117-12121
    • Norbeck, O.1
  • 77
    • 79954998158 scopus 로고    scopus 로고
    • High frequency, sustained T cell responses to PARV4 suggest viral persistence in vivo
    • Simmons R., et al. High frequency, sustained T cell responses to PARV4 suggest viral persistence in vivo. J. Infect. Dis. 2011, 203:1378-1387.
    • (2011) J. Infect. Dis. , vol.203 , pp. 1378-1387
    • Simmons, R.1
  • 78
    • 79956077563 scopus 로고    scopus 로고
    • T cell exhaustion
    • Wherry E.J. T cell exhaustion. Nat. Immunol. 2011, 12:492-499.
    • (2011) Nat. Immunol. , vol.12 , pp. 492-499
    • Wherry, E.J.1
  • 79
    • 32544459770 scopus 로고    scopus 로고
    • Restoring function in exhausted CD8 T cells during chronic viral infection
    • Barber D.L., et al. Restoring function in exhausted CD8 T cells during chronic viral infection. Nature 2006, 439:682-687.
    • (2006) Nature , vol.439 , pp. 682-687
    • Barber, D.L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.