Bcl2L13 is a ceramide synthase inhibitor in glioblastoma

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 15, 2014, Pages 5682-5687

  Jensen, Samuel A ^a   Calvert, Andrea E ^a   Volpert, Giora ^b   Kouri, Fotini M ^a   Hurley, Lisa A ^a   Luciano, Janina P ^a   Wu, Yongfei ^a   Chalastanis, Alexandra ^a   Futerman, Anthony H ^b   Stegh, Alexander H ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Bcl 2 protein family; Intrinsic apoptosis signaling

Indexed keywords

BCL2 LIKE 13 PROTEIN; CASPASE 3; CASPASE 7; CASPASE 9; CERAMIDE SYNTHASE 2; CERAMIDE SYNTHASE 6; CURCUMIN; PROTEIN BCL 2; SYNTHETASE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; APOPTOSIS; ARTICLE; CANCER GROWTH; CARCINOGENESIS; CELLULAR DISTRIBUTION; COMPLEX FORMATION; CONTROLLED STUDY; DIMERIZATION; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE OVEREXPRESSION; GLIOBLASTOMA; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOGOLD LABELING; IMMUNOPRECIPITATION; IN VITRO STUDY; IN VIVO STUDY; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; OUTER MEMBRANE; PHYLOGENY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY; TRANSMISSION ELECTRON MICROSCOPY; WESTERN BLOTTING;

BCL-2 PROTEIN FAMILY; INTRINSIC APOPTOSIS SIGNALING;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; CLONING, MOLECULAR; COMPUTATIONAL BIOLOGY; DNA PRIMERS; DRUG RESISTANCE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE LIBRARY; GLIOBLASTOMA; HUMANS; MEMBRANE PROTEINS; OXIDOREDUCTASES; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS C-BCL-2; SACCHAROMYCES CEREVISIAE; SPHINGOSINE N-ACYLTRANSFERASE; TUMOR SUPPRESSOR PROTEINS; TWO-HYBRID SYSTEM TECHNIQUES;

EID: 84898788114     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1316700111     Document Type: Article

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