Mitochondrial ceramide-rich macrodomains functionalize bax upon irradiation

PLoS ONE

Volumn 6, Issue 6, 2011, Pages

  Lee, Hyunmi ^a   Rotolo, Jimmy A ^a   Mesicek, Judith ^a   Penate Medina, Tuula ^a   Rimner, Andreas ^a   Liao, Wen Chieh ^a   Yin, Xianglei ^a   Ragupathi, Govind ^a   Ehleiter, Desiree ^a   Gulbins, Erich ^b   Zhai, Dayong ^c   Reed, John C ^c   Haimovitz Friedman, Adriana ^a   Fuks, Zvi ^a   Kolesnick, Richard ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b UNIVERSITY OF DUISBURG ESSEN   (Germany)

^c BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CERAMIDE; CYTOCHROME C; FUMONISIN B1; PROTEIN BAX; SPHINGOSINE ACYLTRANSFERASE; DIHYDROCERAMIDE DESATURASE; FUMONISIN; OXIDOREDUCTASE;

ARTICLE; CELL ISOLATION; CELL LEVEL; CELL LYSATE; CELLULAR STRESS RESPONSE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; HELA CELL; IRRADIATION; LIPID COMPOSITION; LIVER MITOCHONDRION; MEMBRANE STRUCTURE; MITOCHONDRIAL PERMEABILITY; MITOCHONDRION; MOLECULAR WEIGHT; NONHUMAN; OLIGOMERIZATION; PROTEIN FUNCTION; PROTEIN ISOLATION; PROTEIN LIPID INTERACTION; PROTEIN LOCALIZATION; PROTEIN SECRETION; PROTEIN SYNTHESIS INHIBITION; ANIMAL; APOPTOSIS; CATTLE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; HUMAN; IONIZING RADIATION; METABOLISM; MITOCHONDRIAL MEMBRANE; MOUSE; PERMEABILITY; PROTEIN QUATERNARY STRUCTURE; RADIATION EXPOSURE;

CAENORHABDITIS ELEGANS; MAMMALIA;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CATTLE; CERAMIDES; FUMONISINS; HELA CELLS; HUMANS; MICE; MITOCHONDRIA; MITOCHONDRIAL MEMBRANES; MOLECULAR WEIGHT; OXIDOREDUCTASES; PERMEABILITY; PROTEIN STRUCTURE, QUATERNARY; RADIATION, IONIZING;

EID: 79958763461     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0019783     Document Type: Article

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