MHC-I expression renders catecholaminergic neurons susceptible to T-cell-mediated degeneration

Nature Communications

Volumn 5, Issue , 2014, Pages

  Cebrián, Carolina ^a   Zucca, Fabio A ^b   Mauri, Pierluigi ^b   Steinbeck, Julius A ^c   Studer, Lorenz ^c   Scherzer, Clemens R ^d   Kanter, Ellen ^a   Budhu, Sadna ^c   Mandelbaum, Jonathan ^e   Vonsattel, Jean P ^a   Zecca, Luigi ^b   Loike, John D ^a   Sulzer, David ^a  

^a New York Presbyterian Morgan Stanley Children's Hospital   (United States)

^b CNR   (Italy)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

^e TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SYNUCLEIN; CATECHOLAMINE; DOPAMINE; GAMMA INTERFERON; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; NEUROMELANIN; OVALBUMIN; HLA ANTIGEN CLASS 1; MELANIN; MESSENGER RNA;

ANTIGEN; BRAIN; GENE EXPRESSION; MAJOR HISTOCOMPATIBILITY COMPLEX; NEUROLOGY; PROTEIN; PUBLIC HEALTH; RODENT;

ADULT; AGED; ANIMAL EXPERIMENT; ANTIGEN EXPRESSION; ARTICLE; CATECHOLAMINE NERVE CELL; CELL DEATH; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DOPAMINERGIC NERVE CELL; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; LOCUS CERULEUS; MALE; MICROGLIA; MOUSE; NERVE DEGENERATION; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; SUBSTANTIA NIGRA; ADRENERGIC NERVE CELL; ANIMAL; CELL SURVIVAL; DRUG EFFECTS; GENE; GENE EXPRESSION PROFILING; GENETICS; METABOLISM; MIDDLE AGED; PARKINSON DISEASE; VERY ELDERLY;

ADRENERGIC NEURONS; AGED; AGED, 80 AND OVER; ALPHA-SYNUCLEIN; ANIMALS; CELL SURVIVAL; DOPAMINE; DOPAMINERGIC NEURONS; FEMALE; GENE EXPRESSION PROFILING; GENES, MHC CLASS I; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; INTERFERON-GAMMA; LOCUS COERULEUS; MALE; MELANINS; MICE; MICROGLIA; MIDDLE AGED; OXIDATIVE STRESS; PARKINSON DISEASE; RNA, MESSENGER; SUBSTANTIA NIGRA; T-LYMPHOCYTES, CYTOTOXIC;

EID: 84898783826     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms4633     Document Type: Article

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