Cordycepol C induces caspase-independent apoptosis in human hepatocellular carcinoma HepG2 cells

Biological and Pharmaceutical Bulletin

Volumn 37, Issue 4, 2014, Pages 608-617

  Sun, Yi Sheng ^a,b   Lv, Long Xian ^a   Zhao, Zhao ^a   He, Xian ^a   You, Lu ^c   Liu, Ji Kai ^d   Li, Yong Quan ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG PROVINCIAL CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^c Department of Orthopedics Huangyan Traditional Chinese Medicine Hospital   (China)

^d KUNMING INSTITUTE OF BOTANY   (China)

Author keywords

Apoptosis; Apoptosis inducing factor; Bax protein; Cordycepol c; Endonuclease g

Indexed keywords

ANTINEOPLASTIC AGENT; APOPTOSIS INDUCING FACTOR; CASPASE; CASPASE INHIBITOR; CORDYCEPOL C; ENDONUCLEASE G; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROCASPASE 3; PROCASPASE 8; PROCASPASE 9; PROTEIN BAX; PROTEIN P53; UNCLASSIFIED DRUG; BENZYLOXYCARBONYLVALYL-ALANYL-ASPARTYL FLUOROMETHYL KETONE; CASPASE 3; CASPASE 9; DEOXYRIBONUCLEASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PEPTIDE CHLOROMETHYL KETONE; SESQUITERPENE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL FRACTIONATION; CELL STRAIN HEPG2; CONTROLLED STUDY; CORDYCEPS; CORDYCEPS OPHIOGLOSSOIDES; CYTOSOL; CYTOTOXICITY; DRUG MECHANISM; DRUG STRUCTURE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; LIVER CELL CARCINOMA; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MOLECULAR MECHANICS; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; RNA INTERFERENCE; WESTERN BLOTTING; WILD TYPE; CARCINOMA, HEPATOCELLULAR; CELL LINE; DRUG EFFECTS; GENE SILENCING; GENETICS; HEPG2 CELL LINE; LIVER NEOPLASMS; METABOLISM; PATHOLOGY;

AMINO ACID CHLOROMETHYL KETONES; ANTINEOPLASTIC AGENTS; APOPTOSIS; APOPTOSIS INDUCING FACTOR; BCL-2-ASSOCIATED X PROTEIN; CARCINOMA, HEPATOCELLULAR; CASPASE 3; CASPASE 9; CASPASE INHIBITORS; CASPASES; CELL LINE; ENDODEOXYRIBONUCLEASES; GENE KNOCKDOWN TECHNIQUES; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; MEMBRANE POTENTIAL, MITOCHONDRIAL; POLY(ADP-RIBOSE) POLYMERASES; SESQUITERPENES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84898720841     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.b13-00877     Document Type: Article

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