Phosphodiesterase type 4 inhibitor rolipram improves survival of spiral ganglion neurons in vitro

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Kranz, Katharina ^a   Warnecke, Athanasia ^a   Lenarz, Thomas ^a   Durisin, Martin ^a   Kranz, Verena Scheper Katharina ^a   Scheper, Verena ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; ROLIPRAM; CYCLIC AMP; PHOSPHODIESTERASE IV; PHOSPHODIESTERASE IV INHIBITOR;

ACOUSTIC NERVE FIBER; ANIMAL CELL; ARTICLE; CELL ISOLATION; CELL SURVIVAL; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; IN VITRO STUDY; NERVE CELL CULTURE; NEUROPROTECTION; NEWBORN; NONHUMAN; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; SPIRAL GANGLION; SURVIVAL RATE; ANIMAL; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; NERVE CELL; PHOSPHORYLATION; PRIMARY CELL CULTURE;

ANIMALS; ANIMALS, NEWBORN; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL SURVIVAL; CYCLIC AMP; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 4; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION; HUMANS; NEURONS; PHOSPHODIESTERASE 4 INHIBITORS; PHOSPHORYLATION; PRIMARY CELL CULTURE; RATS; ROLIPRAM; SIGNAL TRANSDUCTION; SPIRAL GANGLION;

EID: 84898656153     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0092157     Document Type: Article

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