Alterations in protein kinase a signalling and cleft palate: A review

Human and Experimental Toxicology

Volumn 24, Issue 5, 2005, Pages 235-242

  Reddy, Chada S ^a  

^a UNIVERSITY OF MISSOURI   (United States)

Author keywords

Cleft palate; Cyclic AMP; Protein kinase A; Secalonic acid D

Indexed keywords

ADENYLATE CYCLASE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; HORMONE; HYDROCORTISONE; LIGAND; METHYLMERCURY; MYCOTOXIN; SECALONIC ACID D; STEROID; TRANSCRIPTION FACTOR;

ANIMAL MODEL; CELL NUCLEUS; CLEFT PALATE; CRANIOFACIAL DEVELOPMENT; CYCLIC AMP RESPONSIVE ELEMENT; EMBRYO DEVELOPMENT; FACE DEVELOPMENT; HORMONE ACTION; HUMAN; MOUSE; NONHUMAN; ONTOGENY; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN BINDING; REVIEW; SECOND MESSENGER; TERATOGENICITY;

ANIMALS; CLEFT PALATE; CREB-BINDING PROTEIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; HUMANS; MICE; NUCLEAR PROTEINS; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS; XANTHONES;

EID: 20144380786     PISSN: 09603271     EISSN: None     Source Type: Journal    
DOI: 10.1191/0960327105ht514oa     Document Type: Review

References (46)

1. Chin KV, Yang WL, Ravatn R, Kita T, Reitman E, Vettori D, Cvijic ME, Shin M, Iacono L. Reinventing the wheel of cyclic AMP: novel mechanisms of cAMP signaling. Ann NY Acad Sci 2002; 968: 49-64
2. Robinson-White A, Stratakis CA. Protein kinase A signaling 'Cross-Talk' with other pathways in endocrine cells. Ann NY Acad Sci 2002; 968: 256-70.
3. Amieux P, McKnight GS. The essential role of RIα in the maintenance of regulated PKA activity. Ann NY Acad Sci 2002; 968: 75-95.
4. Daniel PB, Walker WH, Habener JF. Cyclic AMP signaling and gene regulation. Annu Rev Nutr 1998; 18: 353-83.
5. Montminy M. Transcriptional regulation by cyclic AMP. Annu Rev Biochem 1997; 66: 807-22.
6. Sassone-Corsi P. Transcription factors responsive to cAMP. Annu Rev Cell Dev Biol 1995; 11: 355-77.
7. Ruppert S, Cole TJ, Boshart M, Schmid E, Schutz G. Multiple mRNA isoforms of the transcription activator protein CREB: generation by alternative splicing and specific expression in primary spermatocytes. EMBO J 1992; 11: 1503-12.
8. Shaywitz AJ, Greenberg ME. CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals. Annu Rev Biochem 1999; 68: 821-61.
9. Hai TW, Liu F, Coukos WJ, Green MR. Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers. Genes Dev 1989; 3: 2083-90.
10. Borrelli E, Montmayeur JP, Foulkes NS, Sassone-Corsi P. Signal transduction and gene control: the cAMP pathway. Crit Rev Oncog 1992; 3: 321-38.
11. Delmas V, van der Hoorn F, Meilstrom B, Jegou B, Sassone-Corsi P. Induction of CREM activator proteins in spermatids: down-stream targets and implications for haploid germ cell differentiation. Mol Endocrinol 1993; 7: 1502-14.
12. Foulkes NS, Borrelli E, Sassone-Corsi P. CREM gene: use of alternative DNA-binding domains generates multiple antagonists of cAMP-induced transcription. Cell 1991; 64: 739-49.
13. Molina CA, Foulkes NS, Lalli E, Sassone-Corsi P. Inducibility and negative autoregulation of CREM: an alternative promoter directs the expression of ICER, an early response repressor. Cell 1993; 75: 875-86.
14. Herdegen T, Leah JD. Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox and CREB/ATF proteins. Brain Res Rev 1998; 28: 370-490.
15. Srivastava RK, Lee YN, Noguchi K, Park YG, Ellis MJ, Jeong JS, Kim SN, Cho-Chung YS. The RIIβ regulatory subunit of protein kinase A binds to cAMP response element: an alternative cAMP signaling pathway. Proc Natl Acad Sci (USA) 1998; 95: 6687-92.
16. Cho YS, Kim MK, Cheadle C, Neary C, Park YG, Becker KG, Cho-Chung YS. A genomic-scale view of the cAMP response element-enhancer decoy: a tumor target-based genetic tool. Proc Natl Acad Sci (USA) 2002; 99: 15626-31.
17. Francis-West P, Ladher R, Barlow A, Graveson A. Signalling interactions during facial development. Mech Dev 1998; 75: 3-28.
18. Pratt RM, Kim CS, Grove RI. Role of glucocorticoids and EGF in normal and abnormal palate development. Curr Top Dev Biol 1984; 19: 81-101.
19. Greene RM, Linask KK, Pisano MM, Weston WM, Lloyd MR. Transmembrane and intracellular signal transduction during palatal ontogeny. J Craniofac Genet Dev Biol 1991; 11: 262-76.
20. Olson F, Massaro E. Developmental pattern of cAMP, adenyl cyclase, and cAMP phosphodiesterase in the palate, lung, and liver of the fetal mouse: alterations resulting from exposure to methylmercury at levels inhibiting palate closure. Teratology 1980; 22: 155-66.
21. ElDeib MMR, Reddy CS. Secalonic acid D-induced changes in palatal cyclic AMP and cyclic GMP in developing mice. Teratology 1988; 37: 343-52.
22. Reddy RV, Reddy CS, ElDeib MMR. Inhibition of adenyl cyclase in pre-fusion mouse palate by secalonic acid D. J Toxicol Environ Health 1994; 41: 173-83.
23. Waterman RE, Palmer G, Palmer J, Palmer S. In Vitro activation of adenyl cyclase by parathyroid hormone and calcitonin during normal and hydrocortisone-induced cleft palate in the golden hamster. Anat Rec 1977; 188: 431-43.
24. Greene RM, Lloyd MR, Uberti M, Nugent P, Pisano MM. Patterns of cyclic AMP- dependent protein kinase gene expression during ontogeny of the murine palate. J Cell Physiol 1995; 163: 431-40.
25. Greene RM, Lloyd MR, Uberti M, Nugent P, Pisano MM. Patterns of cyclic AMP- dependent protein kinase gene expression during ontogeny of the murine palate. J Cell Physiol 1995; 163: 431-40.
26. Weston WM, Greene RM. Developmental changes in phosphorylation of the transcription factor CREB in the embryonic murine palate. J Cell Physiol 1995; 164: 277-85.
27. Balasubramanian G, Hanumegowda UM, Reddy CS. Secalonic acid D alters the nature and inhibits the binding of the transcription factors to the phorbol 12-O-tetradecanoate-13-acetate (TPA)-response element in the developing murine secondary palate. Toxicol Appl Pharmacol 2000; 169: 142-50.
28. Hanumegowda UM, Balasubramanian G, Reddy CS. Secalonic acid D alters the phosphorylation of transcription factors and their binding to cAMP response element in developing murine secondary palate. J Craniofac Genet Dev Biol 2001; 20: 173-82.
29. Greene R, McAndrew V, Lloyd M. Stimulation of palatal glycosamino glycan synthesis by cyclic AMP. Biochem Biophys Res Commun 1982; 107: 232-38.
30. Pisano MM, Schneiderman M, Greene RM. Catecholamine modulation of embryonic palate mesenchymal cell DNA synthesis. J Cell Physiol 1986; 126: 84-92.
31. Erickson RP, Butley MS, Sing CF. H-2 and non-H-2 determined strain variation in palatal shelf and tongue adenosine 3′:5′ cyclic monophosphate: a possible role in the etiology of steroid-induced cleft palate. J Immunogenet 1979; 6: 253-62.
32. Harper K, Burns R, Erickson RP. Genetic aspects of the effects of methylmercury in mice: the incidence of cleft palate and concentrations of adenosine 3′:5′ cyclic monophosphate in tongue and palatal shelf. Teratology 1981; 23: 397-401.
33. Reddy CS. Toxicology of secalonic acid D. In Lacey J ed. Trichothecenes and other mycotoxins. New York, NY: John Wiley & Sons Ltd., 1985: 549-60.
34. Reddy CS, Hayes AW, Williams WL, Ceigler A. Toxicity of secalonic acid D. J Toxicol Environ Health 1979; 5: 1159-69.
35. Donham KJ. Hazardous agents in agricultural dusts and methods of evaluation. Am J Ind Med 1986; 10: 205-20.
36. Grain Quality Newsletter. Health hazards of dust and pesticides. Grain Quality Newsletter 1983; 5: 3.
37. World Book Encyclopedia, 1981.
38. Steyn PS. The isolation, structure and absolute configuration of secalonic acid D, the toxic metabolite of Penicillium oxalicum. Tetrahedron 1970; 26: 51-57.
39. Wang BH, Polya GM. The fungal teratogen secalonic acid D is an inhibitor of protein kinase C and of cyclic AMP-dependent protein kinase. Planta Medica 1996; 62: 111-14.
40. Balasubramanian G, Reddy CS. Selective prevention of secalonic acid D-induced protein kinase inhibition by dimethyl sulfoxide in vitro. Toxicol Sci 1998; 42: 245 (abst).
41. Dhulipala VC, Hanumegowda UM, Balasubramanian G, Reddy CS. Relevance of the palatal protein kinase A pathway to the pathogenesis of cleft palate by secalonic acid D in mice. Toxicol Appl Pharmacol 2004; 194: 270-79.
42. 2+/calmodulin-dependent protein kinases type II and IV involves phosphorylation of a site that negatively regulates activity. Genes Dev 1994; 8: 2527-39.
43. Prosperi E. Multiple roles of the proliferating cell nuclear antigen: DNA replication, repair and cell cycle control (Review). Prog Cell Cycle Res 1997; 3: 193-210.
44. Hanumegowda UM, Judy BM, Welshons WV, Reddy CS. Selective inhibition of murine palatal mesenchymal cell proliferation in vitro by secalonic acid D. Toxicol Sci 2002; 66: 159-65.
45. ElDeib MMR, Reddy CS. A mechanism of dimethylsulfoxide protection against secalonic acid D-induced cleft palate in mice. Teratology 1988; 38: 419-25.
46. Reddy CS. Protein Kinase C and chemical-induced abnormal palate development. Hum Exp Toxicol 2005; 24: 203-14.