Identification of novel knockout and up-regulated targets for improving isoprenoid production in E. coli

Biotechnology Letters

Volumn 36, Issue 5, 2014, Pages 1021-1027

  Wang, Jian feng ^a,b   Meng, Hai lin ^b   Xiong, Zhi qiang ^b   Zhang, Si liang ^a   Wang, Yong ^b  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b INSTITUTE OF PLANT PHYSIOLOGY AND ECOLOGY   (China)

Author keywords

E. coli; Flux distribution analysis; Genome scale model; Isoprenoid production; Lycopene; Metabolic flux analysis; Target gene discovery

Indexed keywords

ESCHERICHIA COLI; GENES;

E. COLI; FLUX DISTRIBUTIONS; GENOME-SCALE MODEL; ISOPRENOIDS; LYCOPENES; METABOLIC FLUX ANALYSIS; TARGET GENES;

LIPIDS;

ESCHERICHIA COLI;

BACTERIAL PROTEIN; CAROTENOID; LYCOPENE;

BIOLOGICAL MODEL; COMPUTER SIMULATION; DOWN REGULATION; ESCHERICHIA COLI; FERMENTATION; GENE EXPRESSION REGULATION; GENE INACTIVATION; GENETIC ENGINEERING; GENETICS; METABOLISM; UPREGULATION;

BACTERIAL PROTEINS; CAROTENOIDS; COMPUTER SIMULATION; DOWN-REGULATION; ESCHERICHIA COLI; FERMENTATION; GENE EXPRESSION REGULATION, BACTERIAL; GENE KNOCKOUT TECHNIQUES; GENETIC ENGINEERING; MODELS, BIOLOGICAL; UP-REGULATION;

EID: 84898548474     PISSN: 01415492     EISSN: 15736776     Source Type: Journal    
DOI: 10.1007/s10529-014-1460-2     Document Type: Article

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