-
1
-
-
0025895183
-
Toward a science of metabolic engineering
-
Bailey, J. E. 1991. Toward a science of metabolic engineering. Science 252: 1668-1674.
-
(1991)
Science
, vol.252
, pp. 1668-1674
-
-
Bailey, J.E.1
-
2
-
-
0026508058
-
Flow-injection analysis of micromolar concentrations of glucose and lactate in fermentation media
-
Benthin, S., Nielsen, J., Villadsen, J. 1992. Flow-injection analysis of micromolar concentrations of glucose and lactate in fermentation media. Anal. Chim. Acta. 261: 145-153.
-
(1992)
Anal. Chim. Acta.
, vol.261
, pp. 145-153
-
-
Benthin, S.1
Nielsen, J.2
Villadsen, J.3
-
4
-
-
84966804546
-
Nonequilibrium thermodynamics and its application to bioenergetics
-
Caplan, S. R. 1971. Nonequilibrium thermodynamics and its application to bioenergetics. Curr Top. Bioeng. 4: 1-79.
-
(1971)
Curr Top. Bioeng.
, vol.4
, pp. 1-79
-
-
Caplan, S.R.1
-
5
-
-
0029669439
-
Growth and α-amylase production by Aspergillus oryzae during continuous cultivations
-
Carlsen, M., Nielsen, J., Villadsen, J. 1996. Growth and α-amylase production by Aspergillus oryzae during continuous cultivations. J. Biotechnol. 45: 81-93.
-
(1996)
J. Biotechnol.
, vol.45
, pp. 81-93
-
-
Carlsen, M.1
Nielsen, J.2
Villadsen, J.3
-
6
-
-
0026582376
-
Metabolic control analysis from transient metabolite concentrations
-
Delgado, J., Liao, J. C. 1992. Metabolic control analysis from transient metabolite concentrations. Biochem. J. 282: 919-927.
-
(1992)
Biochem. J.
, vol.282
, pp. 919-927
-
-
Delgado, J.1
Liao, J.C.2
-
7
-
-
0015989446
-
A linear steady-state treatment of enzymatic chains
-
Heinrich, R., Rapoport, T. A. 1974. A linear steady-state treatment of enzymatic chains. Eur. J. Biochem. 42: 89-95.
-
(1974)
Eur. J. Biochem.
, vol.42
, pp. 89-95
-
-
Heinrich, R.1
Rapoport, T.A.2
-
8
-
-
0342576227
-
Growth energetics and metabolic fluxes in continuous cultures of Penicillium chrysogenum
-
Henriksen, C. M., Christensen, L. H., Nielsen, J., Villadsen, J. 1996. Growth energetics and metabolic fluxes in continuous cultures of Penicillium chrysogenum. J. Biotechnol. 45: 149-164.
-
(1996)
J. Biotechnol.
, vol.45
, pp. 149-164
-
-
Henriksen, C.M.1
Christensen, L.H.2
Nielsen, J.3
Villadsen, J.4
-
9
-
-
0028330751
-
Drug synthesis by genetically engineered microorganisms
-
Hutchinson, C. R. 1994. Drug synthesis by genetically engineered microorganisms. Bio/Technology 12: 375-380.
-
(1994)
Bio/Technology
, vol.12
, pp. 375-380
-
-
Hutchinson, C.R.1
-
10
-
-
0029278153
-
Metabolic flux distributions in Penicillium chrysogenum during fed-batch cultivations
-
Jørgensen, H. S., Nielsen, J., Villadsen, J., Mollgaard, H. 1995. Metabolic flux distributions in Penicillium chrysogenum during fed-batch cultivations. Biotechnol. Bioeng. 46: 117-131.
-
(1995)
Biotechnol. Bioeng.
, vol.46
, pp. 117-131
-
-
Jørgensen, H.S.1
Nielsen, J.2
Villadsen, J.3
Mollgaard, H.4
-
12
-
-
0029921988
-
Alleviation of glucose repression on maltose metabolism by MIG1 disruption in Saccharomyces cerevisiae
-
Klein, C. J. L., Olsson, L., Nielsen, J., Rønnov, B., Dalgaard-Mikkelsen, J. 1996. Alleviation of glucose repression on maltose metabolism by MIG1 disruption in Saccharomyces cerevisiae. Appl. Environ. Microbiol. 62: 4441-4449.
-
(1996)
Appl. Environ. Microbiol.
, vol.62
, pp. 4441-4449
-
-
Klein, C.J.L.1
Olsson, L.2
Nielsen, J.3
Rønnov, B.4
Dalgaard-Mikkelsen, J.5
-
13
-
-
0021341080
-
A mathematical model for λdv plasmid replication: Analysis of wild-type plasmid
-
Lee, S. B., Bailey, J. E. 1994a. A mathematical model for λdv plasmid replication: Analysis of wild-type plasmid. Gene 11: 151-165.
-
(1994)
Gene
, vol.11
, pp. 151-165
-
-
Lee, S.B.1
Bailey, J.E.2
-
14
-
-
0021348306
-
A mathematical model for λdv plasmid replication: Analysis of copy number mutants
-
Lee, S. B., Bailey. J. E. 1994b. A mathematical model for λdv plasmid replication: Analysis of copy number mutants. Gene 11: 166-177.
-
(1994)
Gene
, vol.11
, pp. 166-177
-
-
Lee, S.B.1
Bailey, J.E.2
-
15
-
-
0021531796
-
Genetically structured models for lac promoter-operator function in the Escherichia coli chromosome and in multicopy plasmids: Lac operator function
-
Lee, S. B., Bailey, J. E. 1994c. Genetically structured models for lac promoter-operator function in the Escherichia coli chromosome and in multicopy plasmids: Lac operator function. Bioiechnol Bioeng. 26: 1372-1382.
-
(1994)
Bioiechnol Bioeng.
, vol.26
, pp. 1372-1382
-
-
Lee, S.B.1
Bailey, J.E.2
-
16
-
-
2642694839
-
Genetically structured models for lac promoter-operator function in the Escherichia coli chromosome and in multicopy plasmids: Lac promoter function
-
Lee, S. B., Bailey, J. E. 1994d. Genetically structured models for lac promoter-operator function in the Escherichia coli chromosome and in multicopy plasmids: Lac promoter function. Biotechnol. Bioeng. 26: 3383-1389.
-
(1994)
Biotechnol. Bioeng.
, vol.26
, pp. 3383-11389
-
-
Lee, S.B.1
Bailey, J.E.2
-
17
-
-
0030050268
-
Determination of the fluxes in the central metabolism of Corynebacterium glutamicum by nuclear magnetic resonance spectroscopy combined with metabolite balancing
-
Marx, A., de Graaf, A. A., Wiechert, W., Eggeling, L., Sahm, H. 1996. Determination of the fluxes in the central metabolism of Corynebacterium glutamicum by nuclear magnetic resonance spectroscopy combined with metabolite balancing. Biotechnol. Bioeng. 49: 111-129.
-
(1996)
Biotechnol. Bioeng.
, vol.49
, pp. 111-129
-
-
Marx, A.1
De Graaf, A.A.2
Wiechert, W.3
Eggeling, L.4
Sahm, H.5
-
19
-
-
0027908014
-
Engineered biosynthesis of novel polyketides
-
McDaniel, R., Ebert-Khosla, S., Hopwood, D. A., Khosla, C. 1993. Engineered biosynthesis of novel polyketides. Science 262: 1546-1550.
-
(1993)
Science
, vol.262
, pp. 1546-1550
-
-
McDaniel, R.1
Ebert-Khosla, S.2
Hopwood, D.A.3
Khosla, C.4
-
20
-
-
0019319475
-
Linear relation between rate and thermodynamic force in enzyme-catalyzed reactions
-
van der Meer, R., Westerhoff, H. V., van Dam, K. 1980. Linear relation between rate and thermodynamic force in enzyme-catalyzed reactions. Biochim. Biophys. Acta 591: 488-493.
-
(1980)
Biochim. Biophys. Acta
, vol.591
, pp. 488-493
-
-
Meer, R.1
Westerhoff, H.V.2
Van Dam, K.3
-
21
-
-
0028971232
-
Induction and repression of α-amylase production in batch and continuous cultures of Aspergillus oryzae
-
Mørkeberg, R., Carlsen, M., Nielsen, J. 1995. Induction and repression of α-amylase production in batch and continuous cultures of Aspergillus oryzae. Microbiol. 141: 2449-2454.
-
(1995)
Microbiol.
, vol.141
, pp. 2449-2454
-
-
Mørkeberg, R.1
Carlsen, M.2
Nielsen, J.3
-
22
-
-
2642685731
-
Physiological engineering-towards a new science
-
London
-
Nielsen, J. 1994. Physiological engineering-towards a new science, pp. 30-38. Proc. the 1994 IChemE Research Event, London.
-
(1994)
Proc. the 1994 IChemE Research Event
, pp. 30-38
-
-
Nielsen, J.1
-
23
-
-
0031018721
-
Metabolic control analysis of biochemical pathways based on a thermokinetic description of reaction rates
-
Nielsen, J. 1997. Metabolic control analysis of biochemical pathways based on a thermokinetic description of reaction rates. Biochem. J. 321: 133-138.
-
(1997)
Biochem. J.
, vol.321
, pp. 133-138
-
-
Nielsen, J.1
-
24
-
-
0029294006
-
Metabolic control analysis of the penicillin biosynthetic pathway in a high yielding strain of Penicillium chrysogenum
-
Nielsen, J., Jørgensen, H. S. 1995. Metabolic control analysis of the penicillin biosynthetic pathway in a high yielding strain of Penicillium chrysogenum. Biotechnol. Prog. 11: 299-305.
-
(1995)
Biotechnol. Prog.
, vol.11
, pp. 299-305
-
-
Nielsen, J.1
Jørgensen, H.S.2
-
25
-
-
0031015551
-
Flux distributions in anaerobic, glucose-limited continuous cultures of Saccharomyces cerevisiae
-
Nissen, T. L., Schulze, U., Nielsen, J., Villadsen, J. 1997. Flux distributions in anaerobic, glucose-limited continuous cultures of Saccharomyces cerevisiae. Microbiol. 143: 203-218.
-
(1997)
Microbiol.
, vol.143
, pp. 203-218
-
-
Nissen, T.L.1
Schulze, U.2
Nielsen, J.3
Villadsen, J.4
-
26
-
-
0030921937
-
Silencing MIG1 in Saccharomyces cerevisiae. Effects of antisense MIG1 expression and MIG1 gene disruption
-
Olsson, L., Larsen, M. E., Nielsen, J., Rønnov, B., Dalgaard-Mikkelsen, J. 1997. Silencing MIG1 in Saccharomyces cerevisiae. Effects of antisense MIG1 expression and MIG1 gene disruption. Appl. Environ. Microbiol. 63: 2366-2371.
-
(1997)
Appl. Environ. Microbiol.
, vol.63
, pp. 2366-2371
-
-
Olsson, L.1
Larsen, M.E.2
Nielsen, J.3
Rønnov, B.4
Dalgaard-Mikkelsen, J.5
-
27
-
-
36149006492
-
Reciprocal relations in irreversible processes
-
Onsager, L. 1931. Reciprocal relations in irreversible processes. Phys. Rev. 37: 405-426.
-
(1931)
Phys. Rev.
, vol.37
, pp. 405-426
-
-
Onsager, L.1
-
28
-
-
0029885515
-
Errors associated with experimental determinations of enzyme flux control coefficients
-
Pettersson, G. 1996. Errors associated with experimental determinations of enzyme flux control coefficients. J. Theor. Biol. 179: 191-197.
-
(1996)
J. Theor. Biol.
, vol.179
, pp. 191-197
-
-
Pettersson, G.1
-
29
-
-
15844370671
-
Pathway kinetics and metabolic control analysis of a high-yielding strain of Penicillium chrysogenum during fed-batch cultivations
-
Pissarra, P. N., Nielsen, J., Bazin, M. J. 1996. Pathway kinetics and metabolic control analysis of a high-yielding strain of Penicillium chrysogenum during fed-batch cultivations. Biotechnol. Bioeng. 51: 168-176.
-
(1996)
Biotechnol. Bioeng.
, vol.51
, pp. 168-176
-
-
Pissarra, P.N.1
Nielsen, J.2
Bazin, M.J.3
-
31
-
-
0015854323
-
The thermodynamic description of enzyme-catalyzed reactions. The linear relation between the reaction rate and the affinity
-
Rottenberg, H. 1973. The thermodynamic description of enzyme-catalyzed reactions. The linear relation between the reaction rate and the affinity. Biophys. J. 13:503-511.
-
(1973)
Biophys. J.
, vol.13
, pp. 503-511
-
-
Rottenberg, H.1
-
32
-
-
0343471424
-
Modeling isotopomer distributions in biochemical networks using isotopomer mapping matrices
-
Schmidt, K., Carlsen, M., Nielsen, J., Villadsen, J. 1997. Modeling isotopomer distributions in biochemical networks using isotopomer mapping matrices. Biotechnol. Bioeng. 55: 831-840.
-
(1997)
Biotechnol. Bioeng.
, vol.55
, pp. 831-840
-
-
Schmidt, K.1
Carlsen, M.2
Nielsen, J.3
Villadsen, J.4
-
34
-
-
0025866296
-
Network rigidity and metabolic engineering in metabolite overproduction
-
Stephanopoulos, G., Vallino, J. J. 1991. Network rigidity and metabolic engineering in metabolite overproduction. Science 252: 1675-1681.
-
(1991)
Science
, vol.252
, pp. 1675-1681
-
-
Stephanopoulos, G.1
Vallino, J.J.2
-
35
-
-
2642621705
-
Control of TAKA-amylase A gene: CCAAT binding protein in A. nidulans
-
Munster, Germany
-
Tsukagoshi, N., Kato, M., Aoyama, A., Naruse, F., Kawaguchi, T., Ko bayashi, T. 1996. Control of TAKA-amylase A gene: CCAAT binding protein in A. nidulans. Poster presented at the Third European Conference on Fungal Genetics, Munster, Germany.
-
(1996)
Third European Conference on Fungal Genetics
-
-
Tsukagoshi, N.1
Kato, M.2
Aoyama, A.3
Naruse, F.4
Kawaguchi, T.5
Ko Bayashi, T.6
-
36
-
-
0027572102
-
Metabolic flux distributions in C. glutamicum during growth and lysine overproduction
-
Vallino, J. J., Stephanopoulos, G. 1993. Metabolic flux distributions in C. glutamicum during growth and lysine overproduction. Biotechnol. Bioeng. 41: 633-646.
-
(1993)
Biotechnol. Bioeng.
, vol.41
, pp. 633-646
-
-
Vallino, J.J.1
Stephanopoulos, G.2
-
37
-
-
0028011306
-
Carbon flux distribution at the pyruvate branch point in Corynebacterium glutamicum during lysine overproduction
-
Vallino, J. J., Stephanopoulos, G. 1994a. Carbon flux distribution at the pyruvate branch point in Corynebacterium glutamicum during lysine overproduction. Biotechnol. Prog. 10: 320-326.
-
(1994)
Biotechnol. Prog.
, vol.10
, pp. 320-326
-
-
Vallino, J.J.1
Stephanopoulos, G.2
-
38
-
-
0028086742
-
Carbon flux distributions at the glucose 6-phosphate branch point in Corynebacterium glutamicum during lysine overproduction
-
Vallino, J. J., Stephanopoulos, G. 1994b. Carbon flux distributions at the glucose 6-phosphate branch point in Corynebacterium glutamicum during lysine overproduction. Biotechnol. Prog. 10: 327-334.
-
(1994)
Biotechnol. Prog.
, vol.10
, pp. 327-334
-
-
Vallino, J.J.1
Stephanopoulos, G.2
|