메뉴 건너뛰기




Volumn 13, Issue 1, 2014, Pages

The potential of anti-malarial compounds derived from African medicinal plants, part II: A pharmacological evaluation of non-alkaloids and non-terpenoids

Author keywords

Africa; Malaria; Medicinal plants; Natural products; Traditional medicine

Indexed keywords

ALKALOID; ANTIMALARIAL AGENT; CHALCONE DERIVATIVE; COUMARIN; COUMARIN DERIVATIVE; FLAVANONE DERIVATIVE; FLAVONOID; ISOFLAVONE DERIVATIVE; LIGNAN; PLANT EXTRACT; POLYACETYLENE DERIVATIVE; QUINONE DERIVATIVE; ROTENOID; STEROID; UNCLASSIFIED DRUG; XANTHONE DERIVATIVE;

EID: 84898540115     PISSN: None     EISSN: 14752875     Source Type: Journal    
DOI: 10.1186/1475-2875-13-81     Document Type: Review
Times cited : (117)

References (118)
  • 1
    • 79953093108 scopus 로고    scopus 로고
    • Antiplasmodial natural products
    • 10.3390/molecules16032146
    • Antiplasmodial natural products. Nogueira CR, Lopes LMX, Molecules 2011 16 2146 2190 10.3390/molecules16032146
    • (2011) Molecules , vol.16 , pp. 2146-2190
    • Nogueira, C.R.1    Lopes, L.M.X.2
  • 2
    • 2142659388 scopus 로고    scopus 로고
    • Antimalarial drug resistance
    • DOI 10.1172/JCI200421682
    • Antimalarial drug resistance. White NJ, J Clin Invest 2004 113 1084 1092 10.1172/JCI21682 15085184 (Pubitemid 38544090)
    • (2004) Journal of Clinical Investigation , vol.113 , Issue.8 , pp. 1084-1092
    • White, N.J.1
  • 3
    • 84874499711 scopus 로고    scopus 로고
    • WHO Geneva: World Health Organization Available from http://who.int/ malaria /publications/world-malaria- report-2012/wmr2012-no- profiles.pdf (accessed on August 02, 2013)
    • WHO, World Malaria Report 2012 Geneva: World Health Organization 2012 Available from http://who.int/malaria/publications/world-malaria-report-2012/ wmr2012-no-profiles.pdf (accessed on August 02, 2013)
    • (2012) World Malaria Report 2012
  • 4
    • 77955297752 scopus 로고    scopus 로고
    • Infectious disease - New map illustrates risk from the 'other' malaria
    • 10.1126/science.329.5992.618 20688991
    • Infectious disease-new map illustrates risk from the 'other' malaria. Vogel G, Science 2010 329 618 618 10.1126/science.329.5992.618 20688991
    • (2010) Science , vol.329 , pp. 618-618
    • Vogel, G.1
  • 5
    • 79952759595 scopus 로고    scopus 로고
    • Traditional medicines as a mechanism for driving research innovation in Africa
    • 10.1186/1475-2875-10-S1-S9 21411020
    • Traditional medicines as a mechanism for driving research innovation in Africa. Addae-Mensah I, Fakorede F, Holtel A, Nwaka S, Malar J 2011 10 Suppl 1 9 10.1186/1475-2875-10-S1-S9 21411020
    • (2011) Malar J , vol.10 , Issue.1 , pp. 199
    • Addae-Mensah, I.1    Fakorede, F.2    Holtel, A.3    Nwaka, S.4
  • 6
    • 79952765894 scopus 로고    scopus 로고
    • How can natural products serve as a viable source of lead compounds for the development of new/novel anti-malarials?
    • 10.1186/1475-2875-10-S1-S2 21411013
    • How can natural products serve as a viable source of lead compounds for the development of new/novel anti-malarials? Guantai E, Chibale K, Malar J 2011 10 Suppl 1 2 10.1186/1475-2875-10-S1-S2 21411013
    • (2011) Malar J , vol.10 , Issue.1 , pp. 192
    • Guantai, E.1    Chibale, K.2
  • 7
    • 84878007734 scopus 로고    scopus 로고
    • Malaria in South America: A drug discovery perspective
    • 10.1186/1475-2875-12-168 23706107
    • Malaria in South America: a drug discovery perspective. Cruz LR, Spangenberg T, Lacerda MVG, Wells TNC, Malar J 2013 12 168 10.1186/1475-2875-12- 168 23706107
    • (2013) Malar J , vol.12 , pp. 168
    • Cruz, L.R.1    Spangenberg, T.2    Lacerda, M.V.G.3    Wells, T.N.C.4
  • 8
    • 33646056420 scopus 로고    scopus 로고
    • Drug discovery from natural sources
    • 10.1007/BF02854894 16796374
    • Drug discovery from natural sources. Chin YW, Balunas MJ, Chai HB, Kinghorn AD, AAPS J 2006 8 239 E253 10.1007/BF02854894 16796374
    • (2006) AAPS J , vol.8
    • Chin, Y.W.1    Balunas, M.J.2    Chai, H.B.3    Kinghorn, A.D.4
  • 9
    • 0035044430 scopus 로고    scopus 로고
    • The value of plants used in traditional medicine for drug discovery
    • The value of plants used in traditional medicine for drug discovery. Fabricant DS, Farnsworth NR, Environ Health Perspect 2001 109 69 75 11250806 (Pubitemid 32303231)
    • (2001) Environmental Health Perspectives , vol.109 , Issue.1 , pp. 69-75
    • Fabricant, D.S.1    Farnsworth, N.R.2
  • 10
    • 79952763770 scopus 로고    scopus 로고
    • A call for using natural compounds in the development of new antimalarial treatments-an introduction
    • 10.1186/1475-2875-10-S1-S1 21411010
    • A call for using natural compounds in the development of new antimalarial treatments-an introduction. Ginsburg H, Deharo E, Malar J 2011 10 Suppl 1 1 10.1186/1475-2875-10-S1-S1 21411010
    • (2011) Malar J , vol.10 , Issue.1 , pp. 191
    • Ginsburg, H.1    Deharo, E.2
  • 11
    • 79952741062 scopus 로고    scopus 로고
    • Natural products as starting points for future anti-malarial therapies: Going back to our roots?
    • 10.1186/1475-2875-10-S1-S3 21411014
    • Natural products as starting points for future anti-malarial therapies: going back to our roots? Wells TNC, Malar J 2011 10 Suppl 1 3 10.1186/1475-2875-10-S1-S3 21411014
    • (2011) Malar J , vol.10 , Issue.1 , pp. 193
    • Wells, T.N.C.1
  • 12
    • 84865832714 scopus 로고    scopus 로고
    • The global pipeline of new medicines for the control and elimination of malaria
    • 10.1186/1475-2875-11-316 22958514
    • The global pipeline of new medicines for the control and elimination of malaria. Anthony MP, Burrows JN, Duparc S, JMoehrle J, Wells TNC, Malar J 2012 11 316 10.1186/1475-2875-11-316 22958514
    • (2012) Malar J , vol.11 , pp. 316
    • Anthony, M.P.1    Burrows, J.N.2    Duparc, S.3    Jmoehrle, J.4    Wells, T.N.C.5
  • 13
    • 0033786273 scopus 로고    scopus 로고
    • The potential of African plants as a source of drugs
    • 10.2174/1385272003375923
    • The potential of African plants as a source of drugs. Hostettmann K, Marston A, Ndjoko K, Wolfender JL, Curr Org Chem 2000 4 973 1010 10.2174/1385272003375923
    • (2000) Curr Org Chem , vol.4 , pp. 973-1010
    • Hostettmann, K.1    Marston, A.2    Ndjoko, K.3    Wolfender, J.L.4
  • 14
    • 56449126272 scopus 로고    scopus 로고
    • Natural products: A continuing source of inspiration for the medicinal chemist
    • Amsterdam: Elsevier Science Iwu MM, Wootton JC
    • Natural products: a continuing source of inspiration for the medicinal chemist. Efange SMN, Advances in Phytomedicine Amsterdam: Elsevier Science, Iwu MM, Wootton JC, 2002 61 69
    • (2002) Advances in Phytomedicine , pp. 61-69
    • Efange, S.M.N.1
  • 17
    • 84870289924 scopus 로고    scopus 로고
    • Ethnobotanical survey for potential anti-malarial plants in south-western Nigeria
    • 10.1016/j.jep.2012.10.002 23085021
    • Ethnobotanical survey for potential anti-malarial plants in south-western Nigeria. Dike IP, Obembe OO, Adebiyi FE, J Ethnopharmacol 2012 144 618 626 10.1016/j.jep.2012.10.002 23085021
    • (2012) J Ethnopharmacol , vol.144 , pp. 618-626
    • Dike, I.P.1    Obembe, O.O.2    Adebiyi, F.E.3
  • 18
    • 84871281469 scopus 로고    scopus 로고
    • Phytochemical screening and proximate analysis of eight ethnobotanicals used as antimalaria remedies in Ibadan, Nigeria
    • Phytochemical screening and proximate analysis of eight ethnobotanicals used as antimalaria remedies in Ibadan, Nigeria. Gbadamosi IT, Moody JO, Lawal AM, J Appl Biosci 2011 44 2967 2971
    • (2011) J Appl Biosci , vol.44 , pp. 2967-2971
    • Gbadamosi, I.T.1    Moody, J.O.2    Lawal, A.M.3
  • 19
    • 78651398520 scopus 로고    scopus 로고
    • Potential antimalarials from Nigerian plants: A review
    • 10.1016/j.jep.2010.11.024 21093570
    • Potential antimalarials from Nigerian plants: a review. Adebayo JO, Krettli AU, J Ethnopharmacol 2011 133 289 302 10.1016/j.jep.2010.11.024 21093570
    • (2011) J Ethnopharmacol , vol.133 , pp. 289-302
    • Adebayo, J.O.1    Krettli, A.U.2
  • 20
    • 80051743852 scopus 로고    scopus 로고
    • A review of antimalarial plants used in traditional medicine in communities in Portuguese-Speaking countries: Brazil, Mozambique, Cape Verde, Guinea-Bissau, São Tomé and Príncipe and Angola
    • 21881769
    • A review of antimalarial plants used in traditional medicine in communities in Portuguese-Speaking countries: Brazil, Mozambique, Cape Verde, Guinea-Bissau, São Tomé and Príncipe and Angola. De Silva A JR, De Ramos SA, Machado M, De Moura DF, Neto Z, Canto-Cavalheiro MM, Figueiredo P, Do Rosário VE, Amaral ACF, Lopes D, Mem Inst Oswaldo Cruz 2011 106 Suppl. I 142 158 21881769
    • (2011) Mem Inst Oswaldo Cruz , vol.106 , Issue.1 , pp. 142-158
    • De Silva, A.J.R.1    De Ramos, S.A.2    Machado, M.3    De Moura, D.F.4    Neto, Z.5    Canto-Cavalheiro, M.M.6    Figueiredo, P.7    Do Rosário, V.E.8    Amaral, A.C.F.9    Lopes, D.10
  • 21
    • 0036846482 scopus 로고    scopus 로고
    • Antimalarial activity of extracts and alkaloids isolated from six plants used in traditional medicine in Mali and Sao Tome
    • DOI 10.1002/ptr.1025
    • Antimalarial activity of extracts and alkaloids isolated from six plants used in traditional medicine in Mali and Sao Tome. Ancolio C, Azas N, Mahiou V, Ollivier E, Di Giorgio C, Keita A, Timon-David P, Balansard G, Phytother Res 2002 16 646 649 10.1002/ptr.1025 12410545 (Pubitemid 35334185)
    • (2002) Phytotherapy Research , vol.16 , Issue.7 , pp. 646-649
    • Ancolio, C.1    Azas, N.2    Mahiou, V.3    Ollivier, E.4    Di Giorgio, C.5    Keita, A.6    Timon-David, P.7    Balansard, G.8
  • 22
    • 78650425750 scopus 로고    scopus 로고
    • Harnessing biodiversity: The Malagasy Institute of Applied Research (IMRA)
    • 10.1186/1472-698X-10-S1-S9 21144080
    • Harnessing biodiversity: the Malagasy Institute of Applied Research (IMRA). Puri M, Masum H, Heys J, Singer PA, BMC Int Health Hum Rights 2010 10 Suppl 1 9 10.1186/1472-698X-10-S1-S9 21144080
    • (2010) BMC Int Health Hum Rights , vol.10 , Issue.1 , pp. 199
    • Puri, M.1    Masum, H.2    Heys, J.3    Singer, P.A.4
  • 23
    • 0033023445 scopus 로고    scopus 로고
    • Criblage d'extraits de plantes de Madagascar pour recherche d'activite antipaludique et d'effet potentialisateur de la chloroquine
    • DOI 10.1016/S0378-8741(98)00114-7, PII S0378874198001147
    • Criblage d'extraits de plantes de Madagascar pour recherche d'activité antipaludique et d'effet potentialisateur de la chloroquine. Rasoanaivo P, Ratsimamanga-Urverg S, Ramanitrahasimbola D, Rafatro H, Rakoto-Ratsimamanga A, J Ethnopharmacol 1999 64 117 126 10.1016/S0378-8741(98) 00114-7 (Pubitemid 29130092)
    • (1999) Journal of Ethnopharmacology , vol.64 , Issue.2 , pp. 117-126
    • Rasoanaivo, P.1    Ratsimamanga-Urverg, S.2    Ramanitrahasimbola, D.3    Rafatro, H.4    Rakoto-Ratsimamanga, A.5
  • 26
    • 84891484915 scopus 로고    scopus 로고
    • In vitro antiplasmodial activity of seven plants commonly used against malaria in Burkina Faso
    • In vitro antiplasmodial activity of seven plants commonly used against malaria in Burkina Faso. Kumulungui BS, Ondo-Azi AS, Mintsa NA, Fumoux F, Traore A, J Med Plant Res 2012 6 2284 2288
    • (2012) J Med Plant Res , vol.6 , pp. 2284-2288
    • Kumulungui, B.S.1    Ondo-Azi, A.S.2    Mintsa, N.A.3    Fumoux, F.4    Traore, A.5
  • 28
    • 53449100940 scopus 로고    scopus 로고
    • Investigation South African plants as a source of antimalarial drugs
    • Investigation South African plants as a source of antimalarial drugs. Pillay P, Maharaj VJ, Smith PJ, J Ethnopharmacol 2008 129 438 454
    • (2008) J Ethnopharmacol , vol.129 , pp. 438-454
    • Pillay, P.1    Maharaj, V.J.2    Smith, P.J.3
  • 29
    • 35148849743 scopus 로고    scopus 로고
    • Are West African plants a source of future antimalarial drugs?
    • DOI 10.1016/j.jep.2007.08.012, PII S0378874107004138
    • Are West African plants a source of future antimalarial drugs? Soh PN, Benoit-Vical F, J Ethnopharmacol 2007 114 130 140 10.1016/j.jep.2007.08.012 17884314 (Pubitemid 47539835)
    • (2007) Journal of Ethnopharmacology , vol.114 , Issue.2 , pp. 130-140
    • Soh, P.N.1    Benoit-Vical, F.2
  • 30
    • 35648958186 scopus 로고    scopus 로고
    • Traditional antimalarial phytotherapy remedies used by the Kwale community of the Kenyan Coast
    • DOI 10.1016/j.jep.2007.08.033, PII S0378874107004205
    • Traditional antimalarial phytotherapy remedies used by the Kwale community of the Kenyan Coast. Muthaura CN, Rukunga GM, Chhabra SC, Mungai GM, Njagi ENM, J Ethnopharmacol 2007 114 377 386 10.1016/j.jep.2007.08.033 17904318 (Pubitemid 350026219)
    • (2007) Journal of Ethnopharmacology , vol.114 , Issue.3 , pp. 377-386
    • Muthaura, C.N.1    Rukunga, G.M.2    Chhabra, S.C.3    Mungai, G.M.4    Njagi, E.N.M.5
  • 32
    • 33846950782 scopus 로고    scopus 로고
    • East African medicinal plants as a source of lead compounds for the development of new antimalarial drugs
    • East African medicinal plants as a source of lead compounds for the development of new antimalarial drugs. Waako PJ, Katuura E, Smith P, Folb P, Afr J Ecol 2007 45 Suppl. 1 102 106
    • (2007) Afr J Ecol , vol.45 , Issue.1 , pp. 102-106
    • Waako, P.J.1    Katuura, E.2    Smith, P.3    Folb, P.4
  • 34
    • 70349656494 scopus 로고    scopus 로고
    • In vitro antiplasmodial activity and toxicity assessment of plant extracts used in traditional malaria therapy in the Lake Victoria Region
    • 10.1590/S0074-02762009000500004 19820826
    • In vitro antiplasmodial activity and toxicity assessment of plant extracts used in traditional malaria therapy in the Lake Victoria Region. Ayuko TA, Njau RN, Cornelius W, Leah N, Ndiege IO, Mem Inst Oswaldo Cruz 2009 104 689 694 10.1590/S0074-02762009000500004 19820826
    • (2009) Mem Inst Oswaldo Cruz , vol.104 , pp. 689-694
    • Ayuko, T.A.1    Njau, R.N.2    Cornelius, W.3    Leah, N.4    Ndiege, I.O.5
  • 36
    • 79952002415 scopus 로고    scopus 로고
    • Cameroonian medicinal plants: Pharmacology and derived natural products
    • 21833168
    • Cameroonian medicinal plants: pharmacology and derived natural products. Kuete V, Efferth T, Front Pharmacol 2010 1 123 21833168
    • (2010) Front Pharmacol , vol.1 , pp. 123
    • Kuete, V.1    Efferth, T.2
  • 38
    • 67349205459 scopus 로고    scopus 로고
    • The antimalarial potential of medicinal plants used for the treatment of malaria in Cameroonian folk medicine
    • The antimalarial potential of medicinal plants used for the treatment of malaria in Cameroonian folk medicine. Titanji VPK, Zofou D, Ngemenya MN, Afr J Trad CAM 2008 5 302 321
    • (2008) Afr J Trad CAM , vol.5 , pp. 302-321
    • Titanji, V.P.K.1    Zofou, D.2    Ngemenya, M.N.3
  • 39
    • 70450186312 scopus 로고    scopus 로고
    • Bioactive natural products derived from the East African flora
    • 10.1039/b906089h 19936385
    • Bioactive natural products derived from the East African flora. Magadula JJ, Erasto P, Nat Prod Rep 2009 26 1535 1554 10.1039/b906089h 19936385
    • (2009) Nat Prod Rep , vol.26 , pp. 1535-1554
    • Magadula, J.J.1    Erasto, P.2
  • 40
    • 84888584747 scopus 로고    scopus 로고
    • Bioactive natural products derived from the Central African flora against neglected tropical diseases and HIV
    • 10.1039/c3np70030e 23817666
    • Bioactive natural products derived from the Central African flora against neglected tropical diseases and HIV. Zofou D, Ntie-Kang F, Sippl W, Efange SMN, Nat Prod Rep 2013 30 1098 1120 10.1039/c3np70030e 23817666
    • (2013) Nat Prod Rep , vol.30 , pp. 1098-1120
    • Zofou, D.1    Ntie-Kang, F.2    Sippl, W.3    Efange, S.M.N.4
  • 41
    • 79954480839 scopus 로고    scopus 로고
    • Natural products published in 2009 from plants traditionally used to treat malaria
    • 10.1055/s-0030-1250405 20960389
    • Natural products published in 2009 from plants traditionally used to treat malaria. Bero J, Quetin-Leclercq J, Planta Med 2011 77 631 640 10.1055/s-0030-1250405 20960389
    • (2011) Planta Med , vol.77 , pp. 631-640
    • Bero, J.1    Quetin-Leclercq, J.2
  • 42
    • 0036919713 scopus 로고    scopus 로고
    • Antimalarial activity of plant metabolites
    • DOI 10.1039/b008980j
    • Antimalarial activity of plant metabolites. Schwikkard S, van Heerden FR, Nat Prod Rep 2002 19 675 692 10.1039/b008980j 12521264 (Pubitemid 36029226)
    • (2002) Natural Product Reports , vol.19 , Issue.6 , pp. 675-692
    • Schwikkard, S.1    Van Heerden, F.R.2
  • 43
    • 36448988976 scopus 로고    scopus 로고
    • Antimalarial activity in tropical plants: A review
    • DOI 10.1300/J044v13n01-09
    • Antimalarial activity in tropical plants: a review. Bhatnagara S, Dasa P, J Herbs Spices Med Plants 2007 13 103 132 doi:10.1300/J044v13n01-09 10.1300/J044v13n01-09 (Pubitemid 350163538)
    • (2007) Journal of Herbs, Spices and Medicinal Plants , vol.13 , Issue.1 , pp. 103-132
    • Bhatnagar, S.1    Das, P.2
  • 45
    • 69549135067 scopus 로고    scopus 로고
    • Plant-derived antimalarial agents: New leads and efficient phytomedicines: Part II: Non-alkaloidal natural products
    • 10.3390/molecules14083037 19701144
    • Plant-derived antimalarial agents: new leads and efficient phytomedicines: part II: non-alkaloidal natural products. Batista R, Junior AJS, Oliviera AB, Molecules 2009 14 3037 3072 10.3390/molecules14083037 19701144
    • (2009) Molecules , vol.14 , pp. 3037-3072
    • Batista, R.1    Junior, A.J.S.2    Oliviera, A.B.3
  • 47
    • 75749128268 scopus 로고    scopus 로고
    • Antimalarial compounds isolated from plants used in traditional medicine
    • 10.1211/jpp.61.11.0001 19903367
    • Antimalarial compounds isolated from plants used in traditional medicine. Bero J, Frédérich M, Quetin-Leclercq J, J Pharm Pharmacol 2009 61 1401 1433 10.1211/jpp.61.11.0001 19903367
    • (2009) J Pharm Pharmacol , vol.61 , pp. 1401-1433
    • Bero, J.1    Frédérich, M.2    Quetin-Leclercq, J.3
  • 49
    • 84889963098 scopus 로고    scopus 로고
    • The potential of anti-malarial compounds derived from African medicinal plants, part I: A pharmacological evaluation of alkaloids and terpenoids
    • 10.1186/1475-2875-12-449 24330395
    • The potential of anti-malarial compounds derived from African medicinal plants, part I: a pharmacological evaluation of alkaloids and terpenoids. Amoa Onguéné P, Ntie-Kang F, Lifongo LL, Ndom JC, Sippl W, Mbaze LM, Malar J 2013 12 449 10.1186/1475-2875-12-449 24330395
    • (2013) Malar J , vol.12 , pp. 449
    • Amoa Onguéné, P.1    Ntie-Kang, F.2    Lifongo, L.L.3    Ndom, J.C.4    Sippl, W.5    Mbaze, L.M.6
  • 55
    • 0022910884 scopus 로고
    • L-Glutamine influx in malaria-infected erythrocytes: A target for antimalarials?
    • DOI 10.1016/0169-4758(86)90126-2
    • L-Glutamine influx in malaria-infected erythrocytes: a target for antimalarials? Elford BC, Parasitol Today 1986 2 309 312 10.1016/0169-4758(86) 90126-2 15462745 (Pubitemid 17035900)
    • (1986) Parasitology Today , vol.2 , Issue.11 , pp. 309-312
    • Elford, B.C.1
  • 59
    • 0025823511 scopus 로고
    • Antimalarial activity of Tanzanian plants and their active constituents: The genus Uvaria1
    • 10.1055/s-2006-960113 1775574
    • Antimalarial activity of Tanzanian plants and their active constituents: the genus Uvaria1. Nkunya MH, Weenen H, Bray DH, Mgani QA, Mwasumbi LB, Planta Med 1991 57 341 343 10.1055/s-2006-960113 1775574
    • (1991) Planta Med , vol.57 , pp. 341-343
    • Nkunya, M.H.1    Weenen, H.2    Bray, D.H.3    Mgani, Q.A.4    Mwasumbi, L.B.5
  • 60
    • 34547946909 scopus 로고    scopus 로고
    • A novel antiplasmodial 3′,5′-diformylchalcone and other constituents of Friesodielsia obovata
    • DOI 10.1080/14786410701194310, PII 781220899
    • A novel antiplasmodial 3′,5′-diformylchalcone and other constituents of Friesodielsia obovata. Joseph CC, Magadula JJ, Nkunya MHH, Nat Prod Res 2007 21 1009 1015 10.1080/14786410701194310 17691050 (Pubitemid 47263986)
    • (2007) Natural Product Research , vol.21 , Issue.11 , pp. 1009-1015
    • Joseph, C.C.1    Magadula, J.J.2    Nkunya, M.H.H.3
  • 61
    • 33846186026 scopus 로고    scopus 로고
    • The first 9-hydroxyhomoisoflavanone, and antiplasmodial chalcones, from the aerial exudates of Polygonum senegalense
    • The first 9-hydroxyhomoisoflavanone, and antiplasmodial chalcones, from the aerial exudates of Polygonum senegalense. Midiwo JO, Omoto FM, Yenesew A, Akala HM, Wangui J, Liyala P, Wasunna C, Waters NC, Arkivoc 2007 9 21 27
    • (2007) Arkivoc , vol.9 , pp. 21-27
    • Midiwo, J.O.1    Omoto, F.M.2    Yenesew, A.3    Akala, H.M.4    Wangui, J.5    Liyala, P.6    Wasunna, C.7    Waters, N.C.8
  • 62
    • 0035988144 scopus 로고    scopus 로고
    • A novel phenanthrenolide and C-benzyl dihydrochalcones from Uvaria puguensis
    • A novel phenanthrenolide and C-benzyl dihydrochalcones from Uvaria puguensis. Makangara J, Jonker S, Nkunya M, Nat Prod Lett 2010 16 267 272
    • (2010) Nat Prod Lett , vol.16 , pp. 267-272
    • Makangara, J.1    Jonker, S.2    Nkunya, M.3
  • 68
    • 79959373937 scopus 로고    scopus 로고
    • In vitro antiplasmodial activity and cytotoxicity of crude extracts and compounds from the stem bark of Kigelia africana (Lam.) Benth (Bignoniaceae)
    • 10.1007/s00436-011-2363-y 21487780
    • In vitro antiplasmodial activity and cytotoxicity of crude extracts and compounds from the stem bark of Kigelia africana (Lam.) Benth (Bignoniaceae). Zofou D, Kengne AB, Tene M, Ngemenya MN, Tane P, Titanji VPK, Parasitol Res 2011 108 1383 1390 10.1007/s00436-011-2363-y 21487780
    • (2011) Parasitol Res , vol.108 , pp. 1383-1390
    • Zofou, D.1    Kengne, A.B.2    Tene, M.3    Ngemenya, M.N.4    Tane, P.5    Titanji, V.P.K.6
  • 69
    • 84857058877 scopus 로고    scopus 로고
    • Antimalarial drug interactions of compounds isolated from Kigelia africana (Bignoniaceae) and their synergism with artemether, against the multidrug-resistant W2mef Plasmodium falciparum strain
    • 10.1007/s00436-011-2519-9 21814840
    • Antimalarial drug interactions of compounds isolated from Kigelia africana (Bignoniaceae) and their synergism with artemether, against the multidrug-resistant W2mef Plasmodium falciparum strain. Zofou D, Tene M, Tane P, Titanji VPK, Parasitol Res 2012 110 539 544 10.1007/s00436-011-2519-9 21814840
    • (2012) Parasitol Res , vol.110 , pp. 539-544
    • Zofou, D.1    Tene, M.2    Tane, P.3    Titanji, V.P.K.4
  • 70
    • 84898542393 scopus 로고    scopus 로고
    • Falcipain 2 inhibitors and antiplasmodial compounds from a bio-guided fractionation of the fruits of Sorindeia juglandifolia A. Rich. (Anacardiaceae) growing in Cameroon
    • 10.1186/1475-2875-9-S2-P6
    • Falcipain 2 inhibitors and antiplasmodial compounds from a bio-guided fractionation of the fruits of Sorindeia juglandifolia A. Rich. (Anacardiaceae) growing in Cameroon. Boyom FF, Madiesse EK, Bankeu JJ, Tsouh VP, Lenta BN, Mbacham WF, Tsamo E, Zollo PHA, Gut J, Rosenthal PJ, Malar J 2010 9 Suppl 2 6 10.1186/1475-2875-9-S2-P6
    • (2010) Malar J , vol.9 , Issue.2 , pp. 166
    • Boyom, F.F.1    Madiesse, E.K.2    Bankeu, J.J.3    Tsouh, V.P.4    Lenta, B.N.5    Mbacham, W.F.6    Tsamo, E.7    Zollo, P.H.A.8    Gut, J.9    Rosenthal, P.J.10
  • 72
    • 0034764924 scopus 로고    scopus 로고
    • In vitro antiprotozoal activity of extract and compounds from the stem bark of Combretum molle
    • DOI 10.1002/ptr.897
    • In vitro antiprotozoal activity of extract and compounds from the stem bark of Combretum molle. Asres K, Bucar F, Knauder E, Yardley V, Kendrick H, Croft SL, Phytother Res 2001 15 613 617 10.1002/ptr.897 11746844 (Pubitemid 33021869)
    • (2001) Phytotherapy Research , vol.15 , Issue.7 , pp. 613-617
    • Asres, K.1    Bucar, F.2    Knauder, E.3    Yardley, V.4    Kendrick, H.5    Croft, S.L.6
  • 73
    • 0035996884 scopus 로고    scopus 로고
    • In vitro antiplasmodial activity of extracts of Alchornea cordifolia and identification of an active constituent: Ellagic acid
    • DOI 10.1016/S0378-8741(02)00121-6, PII S0378874102001216
    • In vitro antiplasmodial activity of extracts of Alchornea cordifolia and identification of an active constituent: ellagic acid. Banzouzi JT, Prado R, Menan H, Valentin A, Roumestan C, Mallie M, Pelissier Y, Blache Y, J Ethnopharmacol 2002 81 399 401 10.1016/S0378-8741(02)00121-6 12127243 (Pubitemid 34786326)
    • (2002) Journal of Ethnopharmacology , vol.81 , Issue.3 , pp. 399-401
    • Banzouzi, J.-T.1    Prado, R.2    Menan, H.3    Valentin, A.4    Roumestan, C.5    Mallie, M.6    Pelissier, Y.7    Blache, Y.8
  • 74
    • 41049110011 scopus 로고    scopus 로고
    • An azole, an amide and a limonoid from Vepris uguenensis (Rutaceae)
    • 10.1016/j.phytochem.2007.12.013 18267321
    • An azole, an amide and a limonoid from Vepris uguenensis (Rutaceae). Cheplogoi PK, Mulholland DA, Coombes PH, Randrianarivelojosia M, Phytochemistry 2008 69 1384 1388 10.1016/j.phytochem.2007.12.013 18267321
    • (2008) Phytochemistry , vol.69 , pp. 1384-1388
    • Cheplogoi, P.K.1    Mulholland, D.A.2    Coombes, P.H.3    Randrianarivelojosia, M.4
  • 77
    • 36349000548 scopus 로고    scopus 로고
    • Antiprotozoal polyacetylenes from the Tanzanian medicinal plant Cussonia zimmermannii
    • DOI 10.1021/np0702133
    • Antiprotozoal polyacetylenes from the Tanzanian medicinal plant Cussonia zimmermannii. Senn M, Gunzenhauser S, Brun R, Sequin U, J Nat Prod 2007 70 1565 1569 10.1021/np0702133 17922552 (Pubitemid 350155404)
    • (2007) Journal of Natural Products , vol.70 , Issue.10 , pp. 1565-1569
    • Senn, M.1    Gunzenhauser, S.2    Brun, R.3    Sequin, U.4
  • 78
    • 0001584094 scopus 로고
    • Antimalarial compounds from Hoslundia opposite
    • 10.1016/S0031-9422(00)97526-5
    • Antimalarial compounds from Hoslundia opposite. Achenbach H, Waibel R, Nkunya MHH, Weenen H, Phytochemistry 1992 31 3781 3784 10.1016/S0031-9422(00) 97526-5
    • (1992) Phytochemistry , vol.31 , pp. 3781-3784
    • Achenbach, H.1    Waibel, R.2    Nkunya, M.H.H.3    Weenen, H.4
  • 82
    • 0023931080 scopus 로고
    • The antimalarial activity of Spathodea campanulata stem bark extract on Plasmodium berghei berghei in mice
    • 10.1055/s-2006-962367 3043485
    • The antimalarial activity of Spathodea campanulata stem bark extract on Plasmodium berghei berghei in mice. Makinde JM, Amusan OOG, Adesogan EK, Planta Med 1988 54 122 125 10.1055/s-2006-962367 3043485
    • (1988) Planta Med , vol.54 , pp. 122-125
    • Makinde, J.M.1    Amusan, O.O.G.2    Adesogan, E.K.3
  • 83
    • 0000957734 scopus 로고
    • Knipholone: A unique anthraquinone derivative from Kniphofia foliosa
    • 10.1016/S0031-9422(00)83479-2
    • Knipholone: a unique anthraquinone derivative from Kniphofia foliosa. Dagne E, Steglich W, Phytochemistry 1984 23 1729 1731 10.1016/S0031-9422(00) 83479-2
    • (1984) Phytochemistry , vol.23 , pp. 1729-1731
    • Dagne, E.1    Steglich, W.2
  • 84
    • 0032755181 scopus 로고    scopus 로고
    • Antiplasmodial activity of knipholone and related natural phenylanthraquinones
    • 10.1055/s-2006-960859 10630123
    • Antiplasmodial activity of knipholone and related natural phenylanthraquinones. Bringmann G, Menche D, Bezabih M, Abegaz BM, Kaminsky R, Planta Med 1999 65 757 758 10.1055/s-2006-960859 10630123
    • (1999) Planta Med , vol.65 , pp. 757-758
    • Bringmann, G.1    Menche, D.2    Bezabih, M.3    Abegaz, B.M.4    Kaminsky, R.5
  • 85
    • 0033802810 scopus 로고    scopus 로고
    • Activity of extracts and isolated naphthoquinones from Kigelia pinnata against Plasmodium falciparum
    • 10.1021/np000029g 11000047
    • Activity of extracts and isolated naphthoquinones from Kigelia pinnata against Plasmodium falciparum. Weiss CR, Moideen SVK, Croft SL, Houghton PJ, J Nat Prod 2000 63 1306 1309 10.1021/np000029g 11000047
    • (2000) J Nat Prod , vol.63 , pp. 1306-1309
    • Weiss, C.R.1    Moideen, S.V.K.2    Croft, S.L.3    Houghton, P.J.4
  • 86
    • 0025175143 scopus 로고
    • In vitro antimalarial activity of crude extracts and compounds from Artemisia abrotanum L
    • In vitro antimalarial activity of crude extracts and compounds from Artemisia abrotanum L. Cubukcu B, Bray DH, Warhurst DC, Mericli AH, Ozhatay N, Sariyar G, Phytother Res 1990 4 203 204 10.1002/ptr.2650040510 (Pubitemid 20358838)
    • (1990) Phytotherapy Research , vol.4 , Issue.5 , pp. 203-204
    • Cubukcu, B.1    Bray, D.H.2    Warhust, D.C.3    Mericli, A.H.4    Ozhatay, N.5    Sariyar, G.6
  • 87
    • 0025210470 scopus 로고
    • In vitro antimalarial activity of coutarea latiflora and exostema caribaeum extracts on plasmodium falciparum
    • In vitro antimalarial activity of Coutarea latiflora and Exostema caribaeum extracts on Plasmodium falciparum. Noster S, Kraus L, Planta Med 1990 56 63 65 10.1055/s-2006-960885 2192380 (Pubitemid 20124689)
    • (1990) Planta Medica , vol.56 , Issue.1 , pp. 63-65
    • Noster, S.1    Kraus, Lj.2
  • 88
    • 0033768616 scopus 로고    scopus 로고
    • A new antiplasmodial coumarin from Toddalia asiatica roots
    • 10.1016/S0367-326X(00)00222-7 11077169
    • A new antiplasmodial coumarin from Toddalia asiatica roots. Oketch-Rabah HA, Mwangi JW, Lisgarten J, Mberu EK, Fitoterapia 2000 71 636 640 10.1016/S0367-326X(00)00222-7 11077169
    • (2000) Fitoterapia , vol.71 , pp. 636-640
    • Oketch-Rabah, H.A.1    Mwangi, J.W.2    Lisgarten, J.3    Mberu, E.K.4
  • 90
    • 79958853083 scopus 로고    scopus 로고
    • Hypericum lanceolatum (Hypericaceae) as a potential source of new anti-malarial agents: A bioassay-guided fractionation of the stem bark
    • 10.1186/1475-2875-10-167 21682873
    • Hypericum lanceolatum (Hypericaceae) as a potential source of new anti-malarial agents: a bioassay-guided fractionation of the stem bark. Zofou D, Kowa TK, Wabo HK, Ngemenya MN, Tane P, Titanji VPK, Malar J 2011 10 167 10.1186/1475-2875-10-167 21682873
    • (2011) Malar J , vol.10 , pp. 167
    • Zofou, D.1    Kowa, T.K.2    Wabo, H.K.3    Ngemenya, M.N.4    Tane, P.5    Titanji, V.P.K.6
  • 92
    • 30344477021 scopus 로고    scopus 로고
    • Anti-plasmodial and antioxidant activities of constituents of the seed shells of Symphonia globulifera Linn f
    • DOI 10.1016/j.phytochem.2005.11.004, PII S0031942205006217
    • Anti-plasmodial and antioxidant activities of constituents of the seed shells of Symphonia globulifera Linn f. Ngouela S, Lenta BN, Noungoue DT, Ngoupayo J, Boyom FF, Tsamo E, Gut J, Rosenthal PJ, Connolly JD, Phytochemistry 2006 67 302 306 10.1016/j.phytochem.2005.11.004 16368120 (Pubitemid 43061357)
    • (2006) Phytochemistry , vol.67 , Issue.3 , pp. 302-306
    • Ngouela, S.1    Lenta, B.N.2    Noungoue, D.T.3    Ngoupayo, J.4    Boyom, F.F.5    Tsamo, E.6    Gut, J.7    Rosenthal, P.J.8    Connolly, J.D.9
  • 98
    • 84876392741 scopus 로고    scopus 로고
    • Isolation and relative stereochemistry of lippialactone, a new antimalarial compound Ifrom Lippia javanica
    • 23506784
    • Isolation and relative stereochemistry of lippialactone, a new antimalarial compound Ifrom Lippia javanica. Ludere MT, Van Teunis Ree T, Robert Vleggaar R, Fitoterapia 2013 86 188 192 23506784
    • (2013) Fitoterapia , vol.86 , pp. 188-192
    • Ludere, M.T.1    Van Teunis Ree, T.2    Robert Vleggaar, R.3
  • 99
    • 0000275185 scopus 로고
    • Twenty-one acylphloroglucinol and further constituents from South African Helichrysum species
    • 10.1016/0031-9422(89)80195-5
    • Twenty-one acylphloroglucinol and further constituents from South African Helichrysum species. Jakupovic J, Zdero C, Grenz M, Tsichritzis F, Lehmann L, Hashemi-Nejad SM, Bohlmann F, Phytochemistry 1989 28 1119 1131 10.1016/0031-9422(89)80195-5
    • (1989) Phytochemistry , vol.28 , pp. 1119-1131
    • Jakupovic, J.1    Zdero, C.2    Grenz, M.3    Tsichritzis, F.4    Lehmann, L.5    Hashemi-Nejad, S.M.6    Bohlmann, F.7
  • 100
    • 33745483503 scopus 로고    scopus 로고
    • The antimicrobial, antimalarial and toxicity profiles of helihumulone, leaf essential oil and extracts of Helichrysum cymosum (L.) D. Don subsp. Cymosum
    • DOI 10.1016/j.sajb.2005.07.007, PII S0254629905000426
    • The antimicrobial and toxicity profiles of helihumulone, leaf essential oil and extracts of Helichrysum cymosum (L.) D. Don subsp. cymosum. Van Vuuren SF, Viljoen AM, Van Zyl RL, Van Heerden FR, Baser KHC, S Afr J Bot 2006 72 287 290 10.1016/j.sajb.2005.07.007 (Pubitemid 43963578)
    • (2006) South African Journal of Botany , vol.72 , Issue.2 , pp. 287-290
    • Van Vuuren, S.F.1    Viljoen, A.M.2    Van Zyl, R.L.3    Van Heerden, F.R.4    Baser, K.H.C.5
  • 101
    • 34047111418 scopus 로고    scopus 로고
    • Antiplasmodial hirsutinolides from Vernonia staehelinoides and their utilization towards a simplified pharmacophore
    • DOI 10.1016/j.phytochem.2007.02.019, PII S0031942207001185
    • Antiplasmodial hirsutinolides from Vernonia staehelinoides and their utilization towards a simplified pharmacophore. Pillay P, Vleggaar R, Maharaj VJ, Smith PJ, Lategan CA, Chouteau F, Chibale K, Phytochemistry 2007 68 8 1200 1205 10.1016/j.phytochem.2007.02.019 17408709 (Pubitemid 46528459)
    • (2007) Phytochemistry , vol.68 , Issue.8 , pp. 1200-1205
    • Pillay, P.1    Vleggaar, R.2    Maharaj, V.J.3    Smith, P.J.4    Lategan, C.A.5    Chouteau, F.6    Chibale, K.7
  • 105
    • 79954587965 scopus 로고    scopus 로고
    • Improved traditional phytomedicines in current use for the clinical treatment of malaria
    • 10.1055/s-0030-1250548 21204042
    • Improved traditional phytomedicines in current use for the clinical treatment of malaria. Willcox M, Planta Med 2011 77 662 671 10.1055/s-0030- 1250548 21204042
    • (2011) Planta Med , vol.77 , pp. 662-671
    • Willcox, M.1
  • 106
    • 33745199815 scopus 로고    scopus 로고
    • Virtual ligand screening: Strategies, perspectives and limitations
    • 10.1016/j.drudis.2006.05.012 16793526
    • Virtual ligand screening: strategies, perspectives and limitations. Klebe G, Drug Discov Today 2006 11 580 594 10.1016/j.drudis.2006.05.012 16793526
    • (2006) Drug Discov Today , vol.11 , pp. 580-594
    • Klebe, G.1
  • 113
    • 14944383798 scopus 로고    scopus 로고
    • The evolving role of natural products in drug discovery
    • DOI 10.1038/nrd1657
    • The evolving role of natural products in drug discovery. Koehn FE, Carter GT, Nat Rev Drug Discov 2005 4 206 220 10.1038/nrd1657 15729362 (Pubitemid 40372555)
    • (2005) Nature Reviews Drug Discovery , vol.4 , Issue.3 , pp. 206-220
    • Koehn, F.E.1    Carter, G.T.2
  • 114
    • 52049109838 scopus 로고    scopus 로고
    • Natural products in drug discovery
    • 10.1016/j.drudis.2008.07.004 18691670
    • Natural products in drug discovery. Harvey AL, Drug Discov Today 2008 13 894 901 10.1016/j.drudis.2008.07.004 18691670
    • (2008) Drug Discov Today , vol.13 , pp. 894-901
    • Harvey, A.L.1
  • 115
    • 42949160050 scopus 로고    scopus 로고
    • Natural products as leads to potential drugs: An old process or the new hope for drug discovery?
    • DOI 10.1021/jm0704090
    • Natural products as leads to potential drugs: an old process or the new hope for drug discovery? Newman DJ, J Med Chem 2008 51 2589 2599 10.1021/jm0704090 18393402 (Pubitemid 351620778)
    • (2008) Journal of Medicinal Chemistry , vol.51 , Issue.9 , pp. 2589-2599
    • Newman, D.J.1
  • 116
    • 67650436176 scopus 로고    scopus 로고
    • Drug discovery and natural products: End of an era or an endless frontier?
    • 10.1126/science.1168243 19589993
    • Drug discovery and natural products: end of an era or an endless frontier? Li JWH, Vederas JC, Science 2009 325 161 165 10.1126/science.1168243 19589993
    • (2009) Science , vol.325 , pp. 161-165
    • Li, J.W.H.1    Vederas, J.C.2
  • 117
    • 0031024171 scopus 로고    scopus 로고
    • Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
    • DOI 10.1016/S0169-409X(96)00423-1, PII S0169409X96004231
    • Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Lipinski CA, Lombardo F, Dominy BW, Feeney PJ, Adv Drug Delivery Rev 1997 23 3 25 10.1016/S0169- 409X(96)00423-1 (Pubitemid 27046991)
    • (1997) Advanced Drug Delivery Reviews , vol.23 , Issue.1-3 , pp. 3-25
    • Lipinski, C.A.1    Lombardo, F.2    Dominy, B.W.3    Feeney, P.J.4
  • 118
    • 0037374498 scopus 로고    scopus 로고
    • The price of innovation: New estimates of drug development costs
    • DOI 10.1016/S0167-6296(02)00126-1
    • The price of innovation: new estimates of drug development costs. DiMasi JA, Hansen RW, Grabowsk HG, J Health Econ 2003 22 151 185 10.1016/S0167-6296(02) 00126-1 12606142 (Pubitemid 36279392)
    • (2003) Journal of Health Economics , vol.22 , Issue.2 , pp. 151-185
    • DiMasi, J.A.1    Hansen, R.W.2    Grabowski, H.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.