-
1
-
-
68049123592
-
Artemisinin resistance in Plasmodium falciparum malaria
-
10.1056/NEJMoa0808859. 19641202
-
Artemisinin resistance in Plasmodium falciparum malaria. AM Dondorp F Nosten P Yi D Das AP Phyo J Tarning KM Lwin F Ariey W Hanpithakpong SJ Lee P Ringwald K Silamut M Imwong K Chotivanich P Lim T Herdman SS An S Yeung P Singhasivanon NP Day N Lindegardh D Socheat NJ White, N Engl J Med 2009 361 455 67 10.1056/NEJMoa0808859 19641202
-
(2009)
N Engl J Med
, vol.361
, pp. 455-67
-
-
Dondorp, A.M.1
Nosten, F.2
Yi, P.3
Das, D.4
Phyo, A.P.5
Tarning, J.6
Lwin, K.M.7
Ariey, F.8
Hanpithakpong, W.9
Lee, S.J.10
Ringwald, P.11
Silamut, K.12
Imwong, M.13
Chotivanich, K.14
Lim, P.15
Herdman, T.16
An, S.S.17
Yeung, S.18
Singhasivanon, P.19
Day, N.P.20
Lindegardh, N.21
Socheat, D.22
White, N.J.23
more..
-
2
-
-
55349104084
-
Genomic-scale prioritization of drug targets: The TDR Targets database
-
10.1038/nrd2684. 18927591
-
Genomic-scale prioritization of drug targets: the TDR Targets database. F Agüero B Al-Lazikani M Aslett M Berriman FS Buckner RK Campbell S Carmona IM Carruthers AW Chan F Chen GJ Crowther MA Doyle C Hertz-Fowler AL Hopkins G McAllister S Nwaka JP Overington A Pain GV Paolini U Pieper SA Ralph A Riechers DS Roos A Sali D Shanmugam T Suzuki WC Van Voorhis CL Verlinde, Nat Rev Drug Discov 2008 7 900 7 10.1038/nrd2684 18927591
-
(2008)
Nat Rev Drug Discov
, vol.7
, pp. 900-7
-
-
Agüero, F.1
Al-Lazikani, B.2
Aslett, M.3
Berriman, M.4
Buckner, F.S.5
Campbell, R.K.6
Carmona, S.7
Carruthers, I.M.8
Chan, A.W.9
Chen, F.10
Crowther, G.J.11
Doyle, M.A.12
Hertz-Fowler, C.13
Hopkins, A.L.14
McAllister, G.15
Nwaka, S.16
Overington, J.P.17
Pain, A.18
Paolini, G.V.19
Pieper, U.20
Ralph, S.A.21
Riechers, A.22
Roos, D.S.23
Sali, A.24
Shanmugam, D.25
Suzuki, T.26
Van Voorhis, W.C.27
Verlinde, C.L.28
more..
-
3
-
-
48249095940
-
In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen
-
10.1073/pnas.0802982105. 18579783
-
In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen. D Plouffe A Brinker C McNamara K Henson N Kato K Kuhen A Nagle F Adrin JT Matzen P Anderson TG Nam NS Gray A Chatterjee J Janes SF Yan R Trager JS Caldwell PG Schultz Y Zhou EA Winzeler, Proc Natl Acad Sci U S A 2008 105 9059 64 10.1073/pnas.0802982105 18579783
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 9059-64
-
-
Plouffe, D.1
Brinker, A.2
McNamara, C.3
Henson, K.4
Kato, N.5
Kuhen, K.6
Nagle, A.7
Adrin, F.8
Matzen, J.T.9
Anderson, P.10
Nam, T.G.11
Gray, N.S.12
Chatterjee, A.13
Janes, J.14
Yan, S.F.15
Trager, R.16
Caldwell, J.S.17
Schultz, P.G.18
Zhou, Y.19
Winzeler, E.A.20
more..
-
4
-
-
77952704258
-
Thousands of chemical starting points for antimalarial lead identification
-
10.1038/nature09107. 20485427
-
Thousands of chemical starting points for antimalarial lead identification. FJ Gamo LM Sanz J Vidal C de Cozar E Alvarez JL Lavandera DE Vanderwall DV Green V Kumar S Hasan JR Brown CE Peishoff LR Cardon JF Garcia-Bustos, Nature 2010 465 305 10 10.1038/nature09107 20485427
-
(2010)
Nature
, vol.465
, pp. 305-10
-
-
Gamo, F.J.1
Sanz, L.M.2
Vidal, J.3
De Cozar, C.4
Alvarez, E.5
Lavandera, J.L.6
Vanderwall, D.E.7
Green, D.V.8
Kumar, V.9
Hasan, S.10
Brown, J.R.11
Peishoff, C.E.12
Cardon, L.R.13
Garcia-Bustos, J.F.14
-
5
-
-
77952718950
-
Chemical genetics of Plasmodium falciparum
-
10.1038/nature09099. 20485428
-
Chemical genetics of Plasmodium falciparum. WA Guiguemde AA Shelat D Bouck S Duffy GJ Crowther PH Davis DC Smithson M Connelly J Clark F Zhu MB Jiménez-Díaz MS Martinez EB Wilson AK Tripathi J Gut ER Sharlow I Bathurst F El Mazouni JW Fowble I Forquer PL McGinley S Castro I Angulo-Barturen S Ferrer PJ Rosenthal JL Derisi DJ Sullivan JS Lazo DS Roos MK Riscoe MA Phillips PK Rathod WC Van Voorhis VM Avery RK Guy, Nature 2010 465 311 5 10.1038/nature09099 20485428
-
(2010)
Nature
, vol.465
, pp. 311-5
-
-
Guiguemde, W.A.1
Shelat, A.A.2
Bouck, D.3
Duffy, S.4
Crowther, G.J.5
Davis, P.H.6
Smithson, D.C.7
Connelly, M.8
Clark, J.9
Zhu, F.10
Jiménez-Díaz, M.B.11
Martinez, M.S.12
Wilson, E.B.13
Tripathi, A.K.14
Gut, J.15
Sharlow, E.R.16
Bathurst, I.17
El Mazouni, F.18
Fowble, J.W.19
Forquer, I.20
McGinley, P.L.21
Castro, S.22
Angulo-Barturen, I.23
Ferrer, S.24
Rosenthal, P.J.25
Derisi, J.L.26
Sullivan, D.J.27
Lazo, J.S.28
Roos, D.S.29
Riscoe, M.K.30
Phillips, M.A.31
Rathod, P.K.32
Van Voorhis, W.C.33
Avery, V.M.34
Guy, R.K.35
more..
-
6
-
-
77956286255
-
Microbiology. Is the tide turning for new malaria medicines?
-
10.1126/science.1194923. 20813940
-
Microbiology. Is the tide turning for new malaria medicines? TNC Wells, Science 2010 329 1153 4 10.1126/science.1194923 20813940
-
(2010)
Science
, vol.329
, pp. 1153-4
-
-
Wells, T.N.C.1
-
7
-
-
77956280420
-
Spiroindolones, a new and potent chemotype for 1 the treatment of malaria
-
10.1126/science.1193225. 20813948
-
Spiroindolones, a new and potent chemotype for 1 the treatment of malaria. M Rottmann C McNamara BKS Yeung MCS Lee B Zou B Russell P Seitz D Pluoffe NV Dharia J Tan SB Cohen KR Spencer GE Gonzalez-Paez SB Lakshminarayana A Goh R Suwanarusk T Jegla EK Schmitt HP Beck R Brun F Nosten L Renia V Dartois TH Keller DA Fiddock EA Winzeler TT Diagana, Science 2010 329 1175 80 10.1126/science.1193225 20813948
-
(2010)
Science
, vol.329
, pp. 1175-80
-
-
Rottmann, M.1
McNamara, C.2
Yeung, B.K.S.3
Lee, M.C.S.4
Zou, B.5
Russell, B.6
Seitz, P.7
Pluoffe, D.8
Dharia, N.V.9
Tan, J.10
Cohen, S.B.11
Spencer, K.R.12
Gonzalez-Paez, G.E.13
Lakshminarayana, S.B.14
Goh, A.15
Suwanarusk, R.16
Jegla, T.17
Schmitt, E.K.18
Beck, H.P.19
Brun, R.20
Nosten, F.21
Renia, L.22
Dartois, V.23
Keller, T.H.24
Fiddock, D.A.25
Winzeler, E.A.26
Diagana, T.T.27
more..
-
8
-
-
75749128268
-
Antimalarial compounds isolated from plants used in traditional medicine
-
10.1211/jpp.61.11.0001. 19903367
-
Antimalarial compounds isolated from plants used in traditional medicine. J Bero M Frédérich J Quetin-Leclerq, J Pharm Pharmacol 2009 61 1401 1433 10.1211/jpp.61.11.0001 19903367
-
(2009)
J Pharm Pharmacol
, vol.61
, pp. 1401-1433
-
-
Bero, J.1
Frédérich, M.2
Quetin-Leclerq, J.3
-
9
-
-
0035324944
-
Molecular Complexity and its impact on the probability of finding leads for drug discovery
-
11410068
-
Molecular Complexity and its impact on the probability of finding leads for drug discovery. MM Hann AR Leach G Harper, J Chem Inf Comput Sci 2001 41 856 864 11410068
-
(2001)
J Chem Inf Comput Sci
, vol.41
, pp. 856-864
-
-
Hann, M.M.1
Leach, A.R.2
Harper, G.3
-
10
-
-
43049088827
-
Ligand binding efficiency: Trends, physical basis, and implications
-
DOI 10.1021/jm701255b
-
Ligand Binding Efficiency: Trends Physical Basis and Implications. CH Reynolds BA Tounge SD Bembenek, J Med Chem 2008 51 2432 2438 10.1021/jm701255b 18380424 (Pubitemid 351628504)
-
(2008)
Journal of Medicinal Chemistry
, vol.51
, Issue.8
, pp. 2432-2438
-
-
Reynolds, C.H.1
Tounge, B.A.2
Bembenek, S.D.3
-
12
-
-
0027446185
-
Atovaquone - A novel broad-spectrum anti-infective drug
-
Atovaquone - a novel broad-spectrum anti-infective drug. AT Hudson, Parasitol Today 1993 9 66 8 10.1016/0169-4758(93)90040-M 15463712 (Pubitemid 23038653)
-
(1993)
Parasitology Today
, vol.9
, Issue.2
, pp. 66-68
-
-
Hudson, A.T.1
-
13
-
-
4344630762
-
Identification of an antimalarial synthetic trioxolane drug development candidate
-
DOI 10.1038/nature02779
-
Identification of an antimalarial synthetic trioxolane drug development candidate. JL Vennerstrom S Arbe-Barnes R Brun SA Charman FC Chiu J Chollet Y Dong A Dorn D Hunziker H Matile K McIntosh M Padmanilayam J Santo Tomas C Scheurer B Scorneaux Y Tang H Urwyler S Wittlin WN Charman, Nature 2004 430 900 4 10.1038/nature02779 15318224 (Pubitemid 39119218)
-
(2004)
Nature
, vol.430
, Issue.7002
, pp. 900-904
-
-
Vennerstrom, J.L.1
Arbe-Barnes, S.2
Brun, R.3
Charman, S.A.4
Chiu, F.C.K.5
Chollet, J.6
Dong, Y.7
Dorn, A.8
Hunziker, D.9
Matile, H.10
McIntosh, K.11
Padmanilayam, M.12
Santo Tomas, J.13
Scheurer, C.14
Scorneaux, B.15
Tang, Y.16
Urwyler, H.17
Wittlin, S.18
Charman, W.H.19
-
14
-
-
77950571108
-
New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays
-
10.1021/jm901137j. 20131845
-
New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays. JB Baell GA Holloway, J Med Chem 2010 53 2719 2740 10.1021/jm901137j 20131845
-
(2010)
J Med Chem
, vol.53
, pp. 2719-2740
-
-
Baell, J.B.1
Holloway, G.A.2
-
15
-
-
29144526737
-
Herb and supplement use in the US adult population
-
DOI 10.1016/j.clinthera.2005.11.004, PII S0149291805002833
-
Herb and supplement use in the US adult population. J Kennedy, Clin Ther 2005 27 1847 1858 10.1016/j.clinthera.2005.11.004 16368456 (Pubitemid 41815236)
-
(2005)
Clinical Therapeutics
, vol.27
, Issue.11
, pp. 1847-1858
-
-
Kennedy, J.1
-
17
-
-
0027512619
-
Rapidly progressive interstitial renal fibrosis in young women: Association with slimming regimen including Chinese herbs
-
DOI 10.1016/0140-6736(93)92984-2
-
Rapidly progressive interstitial renal fibrosis in young women: association with slimming regimen including Chinese herbs. JL Vanherweghem M Depierreux C Tielemans D Abramowicz M Dratwa M Jadoul C Richard D Vandervelde D Verbeelen R Vanhaelen-Fastre M Vanhaelen, Lancet 1993 341 387 391 10.1016/0140-6736(93)92984-2 8094166 (Pubitemid 23048140)
-
(1993)
Lancet
, vol.341
, Issue.8842
, pp. 387-391
-
-
Vanherweghem, J.-L.1
Depierreux, M.2
Tielemans, C.3
Abramowicz, D.4
Dratwa, M.5
Jadoul, M.6
Richard, C.7
Vandervelde, D.8
Verbeelen, D.9
Vanhaelen-Fastre, R.10
Vanhaelen, M.11
-
18
-
-
39449104221
-
Late Onset of Bladder Urothelial Carcinoma After Kidney Transplantation for End-Stage Aristolochic Acid Nephropathy: A Case Series With 15-Year Follow-up
-
DOI 10.1053/j.ajkd.2007.11.015, PII S0272638607015910
-
Late onset of bladder urothelial carcinoma after kidney transplantation for endstage aristolochic acid nephropathy: a case series with 15-year follow-up. A Lemy KM Wissing S Rorive A Zlotta T Roumeguere MC Muniz Martinez C Decaestecker I Salmon D Abramowicz JL Vanherweghem J Nortier, Am J Kidney Dis 2008 51 471 477 10.1053/j.ajkd.2007.11.015 18295063 (Pubitemid 351273477)
-
(2008)
American Journal of Kidney Diseases
, vol.51
, Issue.3
, pp. 471-477
-
-
Lemy, A.1
Wissing, K.M.2
Rorive, S.3
Zlotta, A.4
Roumeguere, T.5
Muniz Martinez, M.-C.6
Decaestecker, C.7
Salmon, I.8
Abramowicz, D.9
Vanherweghem, J.-L.10
Nortier, J.11
-
19
-
-
65349148002
-
The African Network for Drugs and Diagnostics Innovation
-
10.1016/S0140-6736(09)60838-2. 19410700
-
The African Network for Drugs and Diagnostics Innovation. T Mboya-Okeyo RG Ridley S Nwaka ANDI Task Force, Lancet 2009 373 1507 8 10.1016/S0140-6736(09) 60838-2 19410700
-
(2009)
Lancet
, vol.373
, pp. 1507-8
-
-
Mboya-Okeyo, T.1
Ridley, R.G.2
Force Task Andi, N.S.3
-
22
-
-
0030737696
-
Herbal remedies for malaria
-
9204715
-
Herbal remedies for malaria. DA Warrell, Trop Doct 1997 27 suppl 1 5 6 9204715
-
(1997)
Trop Doct
, vol.27
, Issue.SUPPL. 1
, pp. 5-6
-
-
Warrell, D.A.1
-
23
-
-
77954952205
-
Ethnopharmacology, sustainable development and cooperation: The importance of gathering clinical data during field surveys
-
10.1016/j.jep.2010.04.044. 20466053
-
Ethnopharmacology, sustainable development and cooperation: the importance of gathering clinical data during field surveys. B Graz J Falquet E Elisabetsky, J Ethnopharmacol 2010 130 635 8 10.1016/j.jep.2010.04.044 20466053
-
(2010)
J Ethnopharmacol
, vol.130
, pp. 635-8
-
-
Graz, B.1
Falquet, J.2
Elisabetsky, E.3
-
24
-
-
35648975204
-
Argemone mexicana decoction for the treatment of uncomplicated falciparum malaria
-
DOI 10.1016/j.trstmh.2007.05.017, PII S0035920307001629
-
Argemone mexicana decoction for the treatment of uncomplicated falciparum malaria. ML Willcox B Graz J Falquet O Sidibe M Forster D Diallo, Trans R Soc Trop Med Hyg 2007 101 1190 1198 10.1016/j.trstmh.2007.05.017 17920092 (Pubitemid 350028620)
-
(2007)
Transactions of the Royal Society of Tropical Medicine and Hygiene
, vol.101
, Issue.12
, pp. 1190-1198
-
-
Willcox, M.L.1
Graz, B.2
Falquet, J.3
Sidibe, O.4
Forster, M.5
Diallo, D.6
-
25
-
-
0033147882
-
From Changshan to a new antimalarial drug
-
10.1177/030631299029003001
-
From Changshan to a new antimalarial drug. SH Lei, Social Studies of Science 1999 29 323 58 10.1177/030631299029003001
-
(1999)
Social Studies of Science
, vol.29
, pp. 323-58
-
-
Lei, S.H.1
-
26
-
-
44949233606
-
Analysis of the adult human plasma metabolome
-
DOI 10.2217/14622416.9.4.383
-
Analysis of the adult human plasma metabolome. KA Lawton A Berger M Mitchell KE Milgram AM Evans L Guo RW Hanson SC Kalhan JA Ryals MV Milburn, Pharmacogenomics 2008 9 383 397 10.2217/14622416.9.4.383 18384253 (Pubitemid 351803924)
-
(2008)
Pharmacogenomics
, vol.9
, Issue.4
, pp. 383-397
-
-
Lawton, K.A.1
Berger, A.2
Mitchell, M.3
Milgram, K.E.4
Evans, A.M.5
Guo, L.6
Hanson, R.W.7
Kalhan, S.C.8
Ryals, J.A.9
Milburn, M.V.10
-
27
-
-
77952337695
-
Xenobiotic metabolism: A view through the metabolometer
-
10.1021/tx100020p. 20232918
-
Xenobiotic metabolism: a view through the metabolometer. AD Patterson FJ Gonzalez JR Idle, Chem Res Toxicol 2010 23 851 860 10.1021/tx100020p 20232918
-
(2010)
Chem Res Toxicol
, vol.23
, pp. 851-860
-
-
Patterson, A.D.1
Gonzalez, F.J.2
Idle, J.R.3
-
28
-
-
76749083725
-
Targeting the hypnozoite reservoir of Plasmodium vivax: The hidden obstacle to malaria elimination
-
10.1016/j.pt.2009.12.005. 20133198
-
Targeting the hypnozoite reservoir of Plasmodium vivax: the hidden obstacle to malaria elimination. TN Wells JN Burrows JK Baird, Trends Parasitol 2010 26 145 51 10.1016/j.pt.2009.12.005 20133198
-
(2010)
Trends Parasitol
, vol.26
, pp. 145-51
-
-
Wells, T.N.1
Burrows, J.N.2
Baird, J.K.3
-
29
-
-
77955340711
-
Antimalarial activity and toxicity evaluation of a quantified Nauclea pobeguinii extract
-
10.1016/j.jep.2010.05.008. 20470876
-
Antimalarial activity and toxicity evaluation of a quantified Nauclea pobeguinii extract. K Mesia RK Cimanga L Dhooghe P Cos S Apers J Totte G Tona L Pieters AJ Vlietinck L Maes, J Ethnopharmacol 2010 131 10 16 10.1016/j.jep.2010.05.008 20470876
-
(2010)
J Ethnopharmacol
, vol.131
, pp. 10-16
-
-
Mesia, K.1
Cimanga, R.K.2
Dhooghe, L.3
Cos, P.4
Apers, S.5
Totte, J.6
Tona, G.7
Pieters, L.8
Vlietinck, A.J.9
Maes, L.10
-
31
-
-
70349313478
-
Improved murine model of malaria using Plasmodium falciparum competent strains and non-myodepleted NOD-scid IL2-Rgamma null mice engrafted with human erythrocysts
-
10.1128/AAC.00519-09. 19596869
-
Improved murine model of malaria using Plasmodium falciparum competent strains and non-myodepleted NOD-scid IL2-Rgamma null mice engrafted with human erythrocysts. MB Jiménez-Díaz T Mulet S Viera V Gámez H Garuti J Ib̃ez A Alvarez-Doval LD Shultz A Martínez D Gargallo-Viola I Angulo-Barturen, Antimicrob Agents Chemother 2009 53 4533 6 10.1128/AAC.00519-09 19596869
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 4533-6
-
-
Jiménez-Díaz, M.B.1
Mulet, T.2
Viera, S.3
Gámez, V.4
Garuti, H.5
Ib̃ez, J.6
Alvarez-Doval, A.7
Shultz, L.D.8
Martínez, A.9
Gargallo-Viola, D.10
Angulo-Barturen, I.11
-
32
-
-
34548183868
-
Prolonged engraftment of human hepatocytes in mice transgenic for the deleted form of human hepatocyte growth factor
-
DOI 10.1111/j.1872-034X.2007.00139.x
-
Prolonged engraftment of human hepatocytes in mice transgenic for the deleted form of human hepatocyte growth factor. A Krishnan K Viker H Rietema M Telgenkamp B Knudsen M Charlton, Hepatol Res 2007 37 854 862 10.1111/j.1872-034X.2007.00139.x 17573952 (Pubitemid 47308228)
-
(2007)
Hepatology Research
, vol.37
, Issue.10
, pp. 854-862
-
-
Krishnan, A.1
Viker, K.2
Rietema, H.3
Telgenkamp, M.4
Knudsen, B.5
Charlton, M.6
-
34
-
-
0027058828
-
Pharmacokinetics of quinine, quinidine and cinchonine when given as combination
-
Pharmacokinetics of quinine, quinidine and cinchonine when given as combination. J Karbwang D Bunnag T Harinasuta S Chittamas J Berth P Druilhe, Southeast Asian J Trop Med Public Health 1992 23 773 776 1298088 (Pubitemid 23121542)
-
(1992)
Southeast Asian Journal of Tropical Medicine and Public Health
, vol.23
, Issue.4
, pp. 773-776
-
-
Karbwang, J.1
Bunnag, D.2
Harinasuta, T.3
Chittamas, S.4
Berth, J.5
Druilhe, P.6
-
35
-
-
0023082699
-
Potentiation of the antimalarial activity of Qinghaosu by methoxylated flavones
-
10.1016/0035-9203(87)90161-1. 3318019
-
Potentiation of the antimalarial activity of Qinghaosu by methoxylated flavones. BC Elford MF Roberts JD Phillipson RJM Wilson, Trans R Soc Trop Med Hyg 1987 81 434 436 10.1016/0035-9203(87)90161-1 3318019
-
(1987)
Trans R Soc Trop Med Hyg
, vol.81
, pp. 434-436
-
-
Elford, B.C.1
Roberts, M.F.2
Phillipson, J.D.3
Wilson, R.J.M.4
-
36
-
-
77952827501
-
Heyerik A potential synergism with artemsinin against malaria and cancer
-
10.3390/molecules15053135. 20657468
-
Heyerik A potential synergism with artemsinin against malaria and cancer. JFS Ferreira DL Luthria T Sasaki, Molecules 2010 15 3135 3170 10.3390/molecules15053135 20657468
-
(2010)
Molecules
, vol.15
, pp. 3135-3170
-
-
Ferreira, J.F.S.1
Luthria, D.L.2
Sasaki, T.3
-
37
-
-
72349090161
-
Hyperparasitaemia and low dosing are an important source of anti-malarial drug resistance
-
10.1186/1475-2875-8-253. 19906307
-
Hyperparasitaemia and low dosing are an important source of anti-malarial drug resistance. NJ White W Pongtavornpinyo RJ Maude S Saralamba R Aguas K Stepniewska SJ Lee AM Dondorp LJ White NP Day, Malar J 2009 8 253 10.1186/1475-2875-8-253 19906307
-
(2009)
Malar J
, vol.8
, pp. 253
-
-
White, N.J.1
Pongtavornpinyo, W.2
Maude, R.J.3
Saralamba, S.4
Aguas, R.5
Stepniewska, K.6
Lee, S.J.7
Dondorp, A.M.8
White, L.J.9
Day, N.P.10
-
41
-
-
0023890204
-
In vitro activity of natural and synthetic naphthoquinones against erythrocytic stages of Plasmodium falciparum
-
3067810
-
In vitro activity of natural and synthetic naphthoquinones against erythrocytic stages of Plasmodium falciparum. LH Carvalho EM Rocha DS Raslan AB Oliveira AU Krettli, Braz J Med Biol Res 1988 21 485 7 3067810
-
(1988)
Braz J Med Biol Res
, vol.21
, pp. 485-7
-
-
Carvalho, L.H.1
Rocha, E.M.2
Raslan, D.S.3
Oliveira, A.B.4
Krettli, A.U.5
-
42
-
-
33947456942
-
Naphthoquinone Antimalarials. XXIV. A New Synthesis of Lapinone
-
10.1021/ja01158a091
-
Naphthoquinone Antimalarials. XXIV. A New Synthesis of Lapinone. LF Fieser G Fawaz, J Am Chem Soc 1950 72 996 1000 10.1021/ja01158a091
-
(1950)
J Am Chem Soc
, vol.72
, pp. 996-1000
-
-
Fieser, L.F.1
Fawaz, G.2
-
43
-
-
1042294559
-
Randomized controlled trial of a traditional preparation of Artemisia annua L. (Annual Wormwood) in the treatment of malaria
-
DOI 10.1016/j.trstmh.2003.09.001, PII S0035920304000112
-
Randomized controlled trial of a traditional preparation of Artemisia annua L. (Annual Wormwood) in the treatment of malaria. MS Mueller N Runyambo I Wagner S Borrmann K Dietz L Heide, Trans R Soc Trop Med Hyg 2004 98 318 21 10.1016/j.trstmh.2003.09.001 15109558 (Pubitemid 38950411)
-
(2004)
Transactions of the Royal Society of Tropical Medicine and Hygiene
, vol.98
, Issue.5
, pp. 318-321
-
-
Mueller, M.S.1
Runyambo, N.2
Wagner, I.3
Borrmann, S.4
Dietz, K.5
Heide, L.6
-
44
-
-
1042300006
-
Pharmacokinetic study of artemisinin after oral intake of a traditional preparation of Artemisia annua L. (annual wormwood)
-
Pharmacokinetic study of artemisinin after oral intake of a traditional preparation of Artemisia annua L. (annual wormwood). K Räth K Taxis G Walz CH Gleiter SM Li L Heide, Am J Trop Med Hyg 2004 70 128 32 14993622 (Pubitemid 38200515)
-
(2004)
American Journal of Tropical Medicine and Hygiene
, vol.70
, Issue.2
, pp. 128-132
-
-
Rath, K.1
Taxis, K.2
Walz, G.3
Gleiter, C.H.4
Li, S.-M.5
Heide, L.6
-
45
-
-
47549100003
-
Herbal Artemisiae annuae tea preparation compared to sulfadoxinepyrimethaminein the treatment of uncomplicated falciparum malaria in adults: A randomized double-blind clinical trial
-
10.1258/td.2007.060184. 18453510
-
Herbal Artemisiae annuae tea preparation compared to sulfadoxinepyrimethaminein the treatment of uncomplicated falciparum malaria in adults: a randomized double-blind clinical trial. CH Blanke GB Naisabha MB Balema GM Mbarku L Heide MS Mueller, Trop Doct 2008 38 113 116 10.1258/td.2007.060184 18453510
-
(2008)
Trop Doct
, vol.38
, pp. 113-116
-
-
Blanke, C.H.1
Naisabha, G.B.2
Balema, M.B.3
Mbarku, G.M.4
Heide, L.5
Mueller, M.S.6
-
47
-
-
0036142318
-
The antimalarial and cytotoxic drug cryptolepine intercalates into DNA at cytosine-cytosine sites
-
DOI 10.1038/nsb729
-
The antimalarial and cytotoxic drug cryptolepine intercalates into DNA at cytosine-cytosine sites. JN Lisgarten M Coll J Portugal CW Wright J Aymami, Nat Struct Biol 2001 9 57 60 10.1038/nsb729 (Pubitemid 34049181)
-
(2002)
Nature Structural Biology
, vol.9
, Issue.1
, pp. 57-60
-
-
Lisgarten, J.N.1
Coll, M.2
Portugal, J.3
Wright, C.W.4
Aymami, J.5
-
48
-
-
0029946969
-
Antimalarial activity of cryptolepine and some other anhydronium bases
-
DOI 10.1002/(SICI)1099-1573(199606)10:4<361::AID-PTR845>3.0.CO;2-N
-
Antimalarial activity of crytolepine and some other anhydronium bases. CW Wright JD Phillipson SO Awe GC Kirby DC Warhurst J Quetin-Leclerq L Angenot, Phytother Res 1996 10 361 363 10.1002/(SICI)1099-1573(199606)10:4<361::AID- PTR845>3.0.CO;2-N (Pubitemid 26195883)
-
(1996)
Phytotherapy Research
, vol.10
, Issue.4
, pp. 361-363
-
-
Wright, C.W.1
Phillipson, J.D.2
Awe, S.O.3
Kirby, G.C.4
Warhurst, D.C.5
Quetin-Leclercq, J.6
Angenot, L.7
-
49
-
-
79952743038
-
Assessment of the Short-Term Safety and Tolerability of a Quantified 80 % Ethanol Extract from the Stem Bark of Nauclea pobeguinii (PR 259 CT1) in Healthy Volunteers: A Clinical Phase i Study
-
20665369
-
Assessment of the Short-Term Safety and Tolerability of a Quantified 80 % Ethanol Extract from the Stem Bark of Nauclea pobeguinii (PR 259 CT1) in Healthy Volunteers: A Clinical Phase I Study. K Mesia K Cimanga L Tona MM Mampunza N Ntamabyaliro T Muanda T Muyembe J Totté T Mets L Pieters A Vlietinck, Planta Med 2010 20665369
-
(2010)
Planta Med
-
-
Mesia, K.1
Cimanga, K.2
Tona, L.3
Mampunza, M.M.4
Ntamabyaliro, N.5
Muanda, T.6
Muyembe, T.7
Totté, J.8
Mets, T.9
Pieters, L.10
Vlietinck, A.11
-
51
-
-
35648975204
-
Argemone mexicana decoction for the treatment of uncomplicated falciparum malaria
-
DOI 10.1016/j.trstmh.2007.05.017, PII S0035920307001629
-
Argemone mexicana decoction for the treatment of uncomplicated falciparum malaria. ML Willcox B Graz J Falquet O Sidibe M Forster D Diallo, Trans R Soc Trop Med Hyg 2007 101 1190 1198 10.1016/j.trstmh.2007.05.017 17920092 (Pubitemid 350028620)
-
(2007)
Transactions of the Royal Society of Tropical Medicine and Hygiene
, vol.101
, Issue.12
, pp. 1190-1198
-
-
Willcox, M.L.1
Graz, B.2
Falquet, J.3
Sidibe, O.4
Forster, M.5
Diallo, D.6
-
52
-
-
70649095189
-
Argemone mexicana decoction versus artesunate-amodiaquine for the management of malaria in Mali: Policy and public-health implication
-
10.1016/j.trstmh.2009.07.005. 19733875
-
Argemone mexicana decoction versus artesunate-amodiaquine for the management of malaria in Mali: policy and public-health implication. B Graz ML Milcox C Diakite J Falquet F Dackuo S Giani D Siallo, Trans R Soc Trop Med Hyg 2010 104 33 41 10.1016/j.trstmh.2009.07.005 19733875
-
(2010)
Trans R Soc Trop Med Hyg
, vol.104
, pp. 33-41
-
-
Graz, B.1
Milcox, M.L.2
Diakite, C.3
Falquet, J.4
Dackuo, F.5
Giani, S.6
Siallo, D.7
-
53
-
-
52149085960
-
The Analgesic and Antiplasmodial Activities and Toxicology of Vernonia amygdalina
-
10.1089/jmf.2007.0511. 18800909
-
The Analgesic and Antiplasmodial Activities and Toxicology of Vernonia amygdalina. AA Njan B Adzu AG Agaba D Byarugaba S Llera-Diau DR Bangsberg, J Med Food 2008 11 574 581 10.1089/jmf.2007.0511 18800909
-
(2008)
J Med Food
, vol.11
, pp. 574-581
-
-
Njan, A.A.1
Adzu, B.2
Agaba, A.G.3
Byarugaba, D.4
Llera-Diau, S.5
Bangsberg, D.R.6
-
54
-
-
70450172300
-
A clinical trial of Veronia amygdalina in the treatment of uncomplicated malaria
-
10.1089/acm.2009.0098. 19922255
-
A clinical trial of Veronia amygdalina in the treatment of uncomplicated malaria. S Challand M Willcox, J Altern Complement Med 2009 15 1231 1237 10.1089/acm.2009.0098 19922255
-
(2009)
J Altern Complement Med
, vol.15
, pp. 1231-1237
-
-
Challand, S.1
Willcox, M.2
-
55
-
-
0002137585
-
Ch'ang Shan, a Chinese Antimalarial Herb Science
-
10.1126/science.103.2663.59-b
-
Ch'ang Shan, a Chinese Antimalarial Herb Science. CS Jang FY Fu CY Wang KC Huang G Lu TC Chou, Science 1946 103 59 10.1126/science.103.2663.59-b
-
(1946)
Science
, vol.103
, pp. 59
-
-
Jang, C.S.1
Fu, F.Y.2
Wang, C.Y.3
Huang, K.C.4
Lu, G.5
Chou, T.C.6
-
56
-
-
66749087558
-
Synthesis and biological evaluation of febrifugine analogues as potential antimalarial agents
-
10.1016/j.bmc.2009.05.011. 19467876
-
Synthesis and biological evaluation of febrifugine analogues as potential antimalarial agents. S Zhu Q Zhang C Gudise L Wei E Smith Y Zeng, Bioorg Med Chem 2009 17 4496 4502 10.1016/j.bmc.2009.05.011 19467876
-
(2009)
Bioorg Med Chem
, vol.17
, pp. 4496-4502
-
-
Zhu, S.1
Zhang, Q.2
Gudise, C.3
Wei, L.4
Smith, E.5
Zeng, Y.6
-
57
-
-
33749433916
-
Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators
-
DOI 10.1016/j.ccr.2006.09.005, PII S1535610806002820
-
Gene expression signature based chemical genomic prediction identifies a novel class of Hsp90 pathway modifiers. H Hieronymus J Lamb KN Ross XP Peng C Clement A Rodina M Nieto J Du K Stegmaier SM Raj KN Maloney J Clardy WC Hahn G Chiosis TR Golub, Cancer Cell 2006 10 321 330 10.1016/j.ccr.2006.09.005 17010675 (Pubitemid 44512193)
-
(2006)
Cancer Cell
, vol.10
, Issue.4
, pp. 321-330
-
-
Hieronymus, H.1
Lamb, J.2
Ross, K.N.3
Peng, X.P.4
Clement, C.5
Rodina, A.6
Nieto, M.7
Du, J.8
Stegmaier, K.9
Raj, S.M.10
Maloney, K.N.11
Clardy, J.12
Hahn, W.C.13
Chiosis, G.14
Golub, T.R.15
-
59
-
-
34547674598
-
+ cell levels in HIV/AIDS patients
-
DOI 10.1097/MJT.0b013e3180a72199, PII 0004539120070700000011
-
Fractionated neem leaf extract is safe and increases CD4+ cell levels in HIV/AIDS patients. AU Mbah IJ Udeinya EN Shu CP Chijioke T Nubila F Udeinya A Muobuike A Mmuobieri MS Obioma, Am. J. Ther 2007 14 369 374 10.1097/MJT. 0b013e3180a72199 17667213 (Pubitemid 47220848)
-
(2007)
American Journal of Therapeutics
, vol.14
, Issue.4
, pp. 369-374
-
-
Mbah, A.U.1
Udeinya, I.J.2
Shu, E.N.3
Chijioke, C.P.4
Nubila, T.5
Udeinya, F.6
Muobuike, A.7
Mmuobieri, A.8
Obioma, M.S.9
-
60
-
-
0030942434
-
Antimalarial activity of tropical Meliaceae extracts and gedunin derivatives
-
DOI 10.1021/np9605394
-
Antimalarial activity of tropical meliaceae extracts and gedunin derivatives. S Mackinnon T Durst JT Arnason C Angerhofer J Pezzuto PE Sanchez-Winday LJ Poveda M Gbeassor, J Nat Prod 1997 60 336 341 10.1021/np9605394 9134742 (Pubitemid 27184907)
-
(1997)
Journal of Natural Products
, vol.60
, Issue.4
, pp. 336-341
-
-
MacKinnon, S.1
Durst, T.2
Arnason, J.T.3
Angerhofer, C.4
Pezzuto, J.5
Sanchez-Vindas, P.E.6
Poveda, L.J.7
Gbeassor, M.8
-
61
-
-
0141727492
-
Antimalarial activities of gedunin and 7-methoxygedunin and synergistic activity with dillapiol
-
Antimalarial activities of gedunin and 7-methoxygedunin and synergistic activities with dillaiol. S Omar K Godard A Ingham H Hussain V Wongpanich J Pezzuto T Durst C Eklu M Gbeassor P Sanchez-Vindas L Poveda BJR Philogene JT Arnason, Ann Appl Biol 2003 143 135 141 10.1111/j.1744-7348.2003.tb00279.x (Pubitemid 37215944)
-
(2003)
Annals of Applied Biology
, vol.143
, Issue.2
, pp. 135-141
-
-
Omar, S.1
Godard, K.2
Ingham, A.3
Hussain, H.4
Wongpanich, V.5
Pezzuto, J.6
Durst, T.7
Eklu, C.8
Gbeassor, M.9
Sanchez-Vindas, P.10
Poveda, L.11
Philogene, B.J.R.12
Arnason, J.T.13
-
63
-
-
8744257799
-
Traditional herbal medicines for malaria
-
Traditional herbal medicines for malaria. ML Willcox G Bodeker, British Medical Journal 2004 329 1156 1159 10.1136/bmj.329.7475.1156 15539672 (Pubitemid 39524776)
-
(2004)
British Medical Journal
, vol.329
, Issue.7475
, pp. 1156-1159
-
-
Willcox, M.L.1
Bodeker, G.2
|