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Volumn 81, Issue 4, 2009, Pages 715-740

Plant-derived antimalarial agents: New leads and efficient phythomedicines. Part I. alkaloids

Author keywords

Alkaloids; Antimalarial activity; Medicinal plants; Natural products; Phytomedicines

Indexed keywords


EID: 70449397876     PISSN: 00013765     EISSN: 16782690     Source Type: Journal    
DOI: 10.1590/s0001-37652009000400011     Document Type: Article
Times cited : (110)

References (94)
  • 1
    • 20144373298 scopus 로고    scopus 로고
    • Antimalarial ethnobotany: In vitro antiplasmodial activity of seven plants identified in the Nigerian middle belt
    • AJAIYEOBA E ET AL. 2005. Antimalarial ethnobotany: in vitro antiplasmodial activity of seven plants identified in the Nigerian middle belt. Pharm Biol 42: 588-591.
    • (2005) Pharm Biol , vol.42 , pp. 588-591
    • Ajaiyeoba, E.1
  • 2
    • 34249888793 scopus 로고    scopus 로고
    • In vitro inhibition of Plasmodium falciparum by substances isolated from Amazonian antimalarial plants
    • ANDRADE-NETO VF ET AL. 2007. In vitro inhibition of Plasmodium falciparum by substances isolated from Amazonian antimalarial plants. Mem Inst Oswaldo Cruz 102: 359-365.
    • (2007) Mem Inst Oswaldo Cruz , vol.102 , pp. 359-365
    • Andrade-Neto, V.F.1
  • 8
    • 0031131832 scopus 로고    scopus 로고
    • Avaliação clínica do quinino para o tratamento da malária por Plasmodium falciparum
    • BOULOS M, DUTRA AP, DISANTI SM, SHIROMA M AND AMATO NETO V. 1997. Avaliação clínica do quinino para o tratamento da malária por Plasmodium falciparum. Rev Soc Bras Med Trop 30: 211-213.
    • (1997) Rev Soc Bras Med Trop , vol.30 , pp. 211-213
    • Boulos, M.1    Dutra, A.P.2    Disanti, S.M.3    Shiroma, M.4    Amato Neto, V.5
  • 9
    • 37149003047 scopus 로고    scopus 로고
    • Ethnopharmacology and malaria: New hypothetical leads or old efficient antimalarials?
    • BOURDY G, WILLCOX ML, GINSBURG H, RASOANAIVO PH, GRAZ B AND DEHARO E. 2007. Ethnopharmacology and malaria: New hypothetical leads or old efficient antimalarials? Intern J Parasitol 38: 33-41.
    • (2007) Intern J Parasitol , vol.38 , pp. 33-41
    • Bourdy, G.1    Willcox, M.L.2    Ginsburg, H.3    Rasoanaivo, P.H.4    Deharo, E.5
  • 11
    • 33847588216 scopus 로고    scopus 로고
    • BRASIL., Departamento de Vigilância Epidemiológica. Ações de controle da malária: manual para profissionais de saúde básica, Brasília, Editora Ministério da Saúde
    • BRASIL. 2006. Ministério da Saúde. Secretaria de Vigilância em Saúde. Departamento de Vigilância Epidemiológica. Ações de controle da malária: manual para profissionais de saúde básica. Brasília, Editora Ministério da Saúde, 52 p.
    • (2006) Ministério da Saúde. Secretaria de Vigilância em Saúde , pp. 52
  • 12
    • 70449376963 scopus 로고    scopus 로고
    • Ministério da Saúde Secretaria de Vigilância em Saúde
    • BRASIL
    • BRASIL. 2007. Ministério da Saúde Secretaria de Vigilância em Saúde. Situação epidemiológica da malária no Brasil, 12 p.
    • (2007) Situação epidemiológica da malária no Brasil , pp. 12
  • 13
    • 0034797208 scopus 로고    scopus 로고
    • Stress-related polyketide metabolism of Diocophyllaceae and Ancistrocladaceae
    • BRINGMANN G AND FEINEIS D. 2001. Stress-related polyketide metabolism of Diocophyllaceae and Ancistrocladaceae. J Exp Bot 52: 2015-2022.
    • (2001) J Exp Bot , vol.52 , pp. 2015-2022
    • Bringmann, G.1    Feineis, D.2
  • 15
    • 0037076950 scopus 로고    scopus 로고
    • Dioncophylline E from Dioncophyllum thollonii, the first 7,3'-coupled dioncophyllaceous naphthylisoquinoline alkaloid
    • BRINGMANN G, MESSER K, WOLF K, MÜHLBACHER J, GRÜNE M AND LOUIS AM. 2002. Dioncophylline E from Dioncophyllum thollonii, the first 7,3'-coupled dioncophyllaceous naphthylisoquinoline alkaloid. Phytochem 60: 389-397.
    • (2002) Phytochem , vol.60 , pp. 389-397
    • Bringmann, G.1    Messer, K.2    Wolf, K.3    Mühlbacher, J.4    Grüne, M.5    Louis, A.M.6
  • 16
    • 0037310714 scopus 로고    scopus 로고
    • Habropetaline A, an antimalarial naphthylisoquinoline alkalaoid from Triphyophyllum peltatum
    • BRINGMANN G, MESSER K, SCHWÖBEL B, BRUN R AND ASSI LA. 2003. Habropetaline A, an antimalarial naphthylisoquinoline alkalaoid from Triphyophyllum peltatum. Phytochem 62: 345-349.
    • (2003) Phytochem , vol.62 , pp. 345-349
    • Bringmann, G.1    Messer, K.2    Schwöbel, B.3    Brun, R.4    Assi, L.A.5
  • 17
    • 70449441045 scopus 로고    scopus 로고
    • CDC - CENTER FOR DISEASE CONTROL, Accessed on 08/12/2008
    • CDC - CENTER FOR DISEASE CONTROL. 2008. Malaria. Biology. Accessed on 08/12/2008: http://www.cdc.gov/malaria/biology/index.htm.
    • (2008) Malaria. Biology
  • 18
    • 33845910913 scopus 로고    scopus 로고
    • A plant-derived morphinan as a novel lead compound active against malaria liver stages
    • CARRAZ M ET AL. 2006. A plant-derived morphinan as a novel lead compound active against malaria liver stages. PLoS Medicine 3: 2392-2402.
    • (2006) PLoS Medicine , vol.3 , pp. 2392-2402
    • Carraz, M.1
  • 19
    • 0026320689 scopus 로고
    • Antimalarial activity of crude extracts from brazilian plants studied in vivo in Plasmodium berghei-infected mice and in vitro against Plasmodium falciparum in culture
    • CARVALHO LH, BRANDÃO MGL, SANTOS-FILHO D, LOPES JLC AND KRETTLI AU. 1991. Antimalarial activity of crude extracts from brazilian plants studied in vivo in Plasmodium berghei-infected mice and in vitro against Plasmodium falciparum in culture. Brazilian J Med Biol Res 24: 1113-1123.
    • (1991) Brazilian J Med Biol Res , vol.24 , pp. 1113-1123
    • Carvalho, L.H.1    Brandão, M.G.L.2    Lopes, J.L.C.3    Krettli, A.U.4
  • 22
    • 0034265114 scopus 로고    scopus 로고
    • An initial examination of the epidemiology of malaria in the state of Roraima, in the Brazilian Amazon basin
    • CHAVES SS AND RODRIGUES LC. 2000. An initial examination of the epidemiology of malaria in the state of Roraima, in the Brazilian Amazon basin. Rev Inst Med Trop São Paulo 42: 269-275.
    • (2000) Rev Inst Med Trop São Paulo , vol.42 , pp. 269-275
    • Chaves, S.S.1    Rodrigues, L.C.2
  • 23
    • 0030754049 scopus 로고    scopus 로고
    • In vitro and in vivo antiplasmodial activity of cryptolepine and related alkaloids from Cryptolepis sanguinolenta
    • CIMANGA K, BRUYNE TD, PIETERS L AND VLIETINCK AJ. 1997. In vitro and in vivo antiplasmodial activity of cryptolepine and related alkaloids from Cryptolepis sanguinolenta. J Nat Prod 60: 688-691.
    • (1997) J Nat Prod , vol.60 , pp. 688-691
    • Cimanga, K.1    Bruyne, T.D.2    Pieters, L.3    Vlietinck, A.J.4
  • 24
    • 23044490704 scopus 로고    scopus 로고
    • Plants as source of anticancer agents
    • CRAGG GM AND NEWMAN DJ. 2005. Plants as source of anticancer agents. J Ethnopharm 100: 72-79.
    • (2005) J Ethnopharm , vol.100 , pp. 72-79
    • Cragg, G.M.1    Newman, D.J.2
  • 26
    • 0034908844 scopus 로고    scopus 로고
    • A search for natural bioactive compounds in Bolivia through a multidisciplinary approach. Part V. Evaluation of the antimalarial activity of plants used by the Tacan Inidians
    • DEHARO E, BOURDY G, QUENEVO C, MUÑOZ V, RUIZ G AND SAUVAIN M. 2001. A search for natural bioactive compounds in Bolivia through a multidisciplinary approach. Part V. Evaluation of the antimalarial activity of plants used by the Tacan Inidians. J Ethnopharmacol 77: 91-98.
    • (2001) J Ethnopharmacol , vol.77 , pp. 91-98
    • Deharo, E.1    Bourdy, G.2    Quenevo, C.3    Muñoz, V.4    Ruiz, G.5    Sauvain, M.6
  • 27
    • 0036557772 scopus 로고    scopus 로고
    • A nonradioabelled ferriprotoporphyrin IX biomineralization inhibi1995. Potent antimalarial activity of the alkaloid nitition test for the high throughput screening of antimalarial dine, isolated from a Kenyan herbal remedy. Antimicrob compounds
    • DEHARO E, GARCIA RN, OPRTO P, GIMENEZ A, SAUVIN M, JULIIAN V AND GINSBURG H. 2002. A nonradioabelled ferriprotoporphyrin IX biomineralization inhibi1995. Potent antimalarial activity of the alkaloid nitition test for the high throughput screening of antimalarial dine, isolated from a Kenyan herbal remedy. Antimicrob compounds. Exp Parasitol 100: 252-256
    • (2002) Exp Parasitol , vol.1 , pp. 252-256
    • Deharo, E.1    Garcia, R.N.2    Oprto, P.3    Gimenez, A.4    Sauvin, M.5    Juliian, V.6    Ginsburg, H.7
  • 28
    • 0018606732 scopus 로고
    • Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique
    • DESJARDINS RE, CANFIELD CJ, HAYNES JD AND CHULAY JD. 1979. Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique. Antimicrob Agents Chemother 16: 710-718.
    • (1979) Antimicrob Agents Chemother , vol.16 , pp. 710-718
    • Desjardins, R.E.1    Canfield, C.J.2    Haynes, J.D.3    Chulay, J.D.4
  • 29
    • 41949126684 scopus 로고    scopus 로고
    • In vitro aniplasmodial activity of extract and constituents from Esenbeckia febrifuga, a plant traditionally used to treat malaria in the Brazilian Amazon
    • DOLABELA MF, OLIVEIRA SG, NASCIMENTO JM, PERES JM, WAGNER H, PÓVOA MM AND OLIVEIRA AB. 2008. In vitro aniplasmodial activity of extract and constituents from Esenbeckia febrifuga, a plant traditionally used to treat malaria in the Brazilian Amazon. Phytomedicine 15: 367-372.
    • (2008) Phytomedicine , vol.15 , pp. 367-372
    • Dolabela, M.F.1    Oliveira, S.G.2    Nascimento, J.M.3    Peres, J.M.4    Wagner, H.5    Póvoa, M.M.6    Oliveira, A.B.7
  • 31
    • 0040299136 scopus 로고    scopus 로고
    • Naphtylisoquinoline alkaloids against malaria: Evaluation of the curative potential of dioncophylline C and Dioncopeltine A against Plasmodium berghei in vivo
    • FRANÇOIS G, TIMPERMAN G, ELING W, AKE ASSI L AND BRINGMANN G. 1997. Naphtylisoquinoline alkaloids against malaria: Evaluation of the curative potential of dioncophylline C and Dioncopeltine A against Plasmodium berghei in vivo. Antimicrob Agents Chemother 41: 2533-2539.
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 2533-2539
    • François, G.1    Timperman, G.2    Eling, W.3    Ake Assi, L.4    Bringmann, G.5
  • 32
    • 0032876288 scopus 로고    scopus 로고
    • In vitro activities of Strychnos alkaloids and and extracts against Plasmodium falciparum
    • FREDERICH M, HAYRTTE MP, TITS M, DE MOL P AND ANGENOT L. 1999. In vitro activities of Strychnos alkaloids and and extracts against Plasmodium falciparum. Antimicrob Agents Chemother 43: 2328-2331.
    • (1999) Antimicrob Agents Chemother , vol.43 , pp. 2328-2331
    • Frederich, M.1    Hayrtte, M.P.2    Tits, M.3    de Mol, P.4    Angenot, L.5
  • 34
    • 3342978950 scopus 로고    scopus 로고
    • Indole alkaloids from Strychnos species and their antiplasmodial and cytotoxic activities
    • FREDERICH M, TITS M AND ANGENOT L. 2003. Indole alkaloids from Strychnos species and their antiplasmodial and cytotoxic activities. Chem Nat Comp 39: 513-519.
    • (2003) Chem Nat Comp , vol.39 , pp. 513-519
    • Frederich, M.1    Tits, M.2    Angenot, L.3
  • 36
    • 0033963138 scopus 로고    scopus 로고
    • Antiplasmodial activity of the alkaloids of Peschiera fuchsiaefolia
    • FREDERICI E, PALAZZINO G, NICOLETTI M AND GAÇEFFI C. 2000. Antiplasmodial activity of the alkaloids of Peschiera fuchsiaefolia. Planta Med 66: 93-95.
    • (2000) Planta Med , vol.66 , pp. 93-95
    • Frederici, E.1    Palazzino, G.2    Nicoletti, M.3    Gaçeffi, C.4
  • 37
    • 0024489461 scopus 로고
    • In vitro and in vivo activities of atalaphilline and related acridone alkaloids against rodent malaria
    • FUJIOKA H, NISHIYAMA Y, FURUKAWA H AND KUMADA N. 1989. In vitro and in vivo activities of atalaphilline and related acridone alkaloids against rodent malaria. Antimicrob Agents Chemother 33: 6-9.
    • (1989) Antimicrob Agents Chemother , vol.33 , pp. 6-9
    • Fujioka, H.1    Nishiyama, Y.2    Furukawa, H.3    Kumada, N.4
  • 40
    • 0034882210 scopus 로고    scopus 로고
    • Twenty-five years of chemical ecology
    • HARBORNE JB. 2001. Twenty-five years of chemical ecology. Nat Prod Rep 18: 361-379.
    • (2001) Nat Prod Rep , vol.18 , pp. 361-379
    • Harborne, J.B.1
  • 41
    • 44949201430 scopus 로고    scopus 로고
    • Plant-derived natural product research aimed at new drug discovery
    • ITOKAWA H, MORRIS-NATSCHKE SL, AKIYAMA T AND LEE KH. 2008. Plant-derived natural product research aimed at new drug discovery. Nat Med (Tokio) 62(3): 263-280.
    • (2008) Nat Med (Tokio) , vol.62 , Issue.3 , pp. 263-280
    • Itokawa, H.1    Morris-Natschke, S.L.2    Akiyama, T.3    Lee, K.H.4
  • 42
    • 30744444706 scopus 로고    scopus 로고
    • Estudo químico e perfil cromatográfico das cascas de Aspidosperma parvifolium A. DC. ("Pau-Pereira")
    • JÁCOME RLP, OLIVEIRA AB, RASLAN DS AND WAGNER H. 2004. Estudo químico e perfil cromatográfico das cascas de Aspidosperma parvifolium A. DC. ("Pau-Pereira"). Química Nova 27: 897-900.
    • (2004) Química Nova , vol.27 , pp. 897-900
    • Jácome, R.L.P.1    Oliveira, A.B.2    Raslan, D.S.3    Wagner, H.4
  • 43
    • 0032777223 scopus 로고    scopus 로고
    • Two tetrahydroquinoline alkaloids from Galipea officinalis
    • JACQUEMOND-COLLET I, HANNEDOUCHE S, FABRE N, FOURASTÉ I AND MOULIS C. 1999. Two tetrahydroquinoline alkaloids from Galipea officinalis. Phytochem 51: 1167-1169.
    • (1999) Phytochem , vol.51 , pp. 1167-1169
    • Hannedouche, S.1    Fabre, N.2    Fourasté, I.3    Moulis, C.4
  • 44
    • 0036157389 scopus 로고    scopus 로고
    • Antiplasmodial and cytotoxic activity of galipinine and other tetrahydroquinolines from Galipea officinalis
    • JACQUEMOND-COLLET I, BENOIT-VICAL F, VALENTIN A, STANISLAS E, MALLIE M AND FOURASTE I. 2002. Antiplasmodial and cytotoxic activity of galipinine and other tetrahydroquinolines from Galipea officinalis. Planta Med 68: 68-69.
    • (2002) Planta Med , vol.68 , pp. 68-69
    • Valentin, A.1    Stanislas, E.2    Mallie, M.3    Fouraste, I.4
  • 45
    • 0036682302 scopus 로고    scopus 로고
    • Synthesis, cytotixicity, antiplasmodial and anti-trypanosomal activity of new neocryptolepine derivatives
    • JONCKERS THM ET AL. 2002. Synthesis, cytotixicity, antiplasmodial and anti-trypanosomal activity of new neocryptolepine derivatives. J Med Chem 45: 3497-3508.
    • (2002) J Med Chem , vol.45 , pp. 3497-3508
    • Jonckers, T.H.M.1
  • 46
    • 33745183774 scopus 로고    scopus 로고
    • Validation of use a traditional anti-malarial remedy from French Guiana, Zanthoxylum rhoifolium Lam
    • JULIAN V, BOURDY G, GEORGES S, MAUREL S AND SAUVAIN M. 2006. Validation of use a traditional anti-malarial remedy from French Guiana, Zanthoxylum rhoifolium Lam. J Ethnopharmacol 106: 348-352.
    • (2006) J Ethnopharmacol , vol.106 , pp. 348-352
    • Julian, V.1    Bourdy, G.2    Georges, S.3    Maurel, S.4    Sauvain, M.5
  • 47
    • 0032714668 scopus 로고    scopus 로고
    • Antiplasmodial activity of extracts of three Alstonia species from Thailand
    • KEAWPRADUB N, KIRBY GC, STEELE JCP AND HOUGHTON PJ. 1999. Antiplasmodial activity of extracts of three Alstonia species from Thailand. Planta Med 65: 690-694.
    • (1999) Planta Med , vol.65 , pp. 690-694
    • Keawpradub, N.1    Kirby, G.C.2    Steele, J.C.P.3    Houghton, P.J.4
  • 48
    • 0030460608 scopus 로고    scopus 로고
    • Medicinal plants and the control of parasites. Medicinal plants and the control of protozoal disease, with particular reference to malaria
    • KIRBY GC. 1996. Medicinal plants and the control of parasites. Medicinal plants and the control of protozoal disease, with particular reference to malaria. Trans Roy Soc Trop Med Hyg 90: 605-609.
    • (1996) Trans Roy Soc Trop Med Hyg , vol.90 , pp. 605-609
    • Kirby, G.C.1
  • 49
    • 35948932463 scopus 로고    scopus 로고
    • Acessibility and affordability of malaria intervention, treatment and prevention in Africa
    • KOECH DK. 2006. Acessibility and affordability of malaria intervention, treatment and prevention in Africa. African J Health Sci 13: 1-2.
    • (2006) African J Health Sci , vol.13 , pp. 1-2
    • Koech, D.K.1
  • 51
    • 65549118186 scopus 로고    scopus 로고
    • Testing of natural products and synthetic molecules aiming at new antimalarials
    • KRETTLI AU, ADEBAYO JO AND KRETTLI LG. 2009. Testing of natural products and synthetic molecules aiming at new antimalarials. Curr Drug Targets 10(3): 261-270.
    • (2009) Curr Drug Targets , vol.10 , Issue.3 , pp. 261-270
    • Krettli, A.U.1    Adebayo, J.O.2    Krettli, L.G.3
  • 54
    • 0033110869 scopus 로고    scopus 로고
    • Malarone (atovaquone and proguanyl hydrochloride): A review of its clinical development for treatment of malaria. Malarone Clinical Trials Study Group
    • LOOAREESUWAN S, CHULAY JD, CANFIELD CJ AND HUTCHINSON DD. 1999. Malarone (atovaquone and proguanyl hydrochloride): a review of its clinical development for treatment of malaria. Malarone Clinical Trials Study Group. Am J Trop Med Hyg 60: 533-541.
    • (1999) Am J Trop Med Hyg , vol.60 , pp. 533-541
    • Looareesuwan, S.1    Chulay, J.D.2    Canfield, C.J.3    Hutchinson, D.D.4
  • 55
    • 0344517539 scopus 로고
    • Apocynaceae: estudos taxonômicos. Tese de Doutorado. Universidade de Campinas. Campinas, SP, Brasil
    • MARCONDES-FERREIRA NETO WM. 1988. Aspidosperma Mart. nom. cons. Apocynaceae: estudos taxonômicos. Tese de Doutorado. Universidade de Campinas. Campinas, SP, Brasil.
    • (1988) Aspidosperma Mart. nom. cons
    • Marcondes-Ferreira neto, W.M.1
  • 56
    • 0036320702 scopus 로고    scopus 로고
    • Isolation and in vitro antiplasmodial activities of alkaloids from Teclea trichocarpa: In vivo antimalarial activity and X-ray crystal structure of normelicopicine
    • MAURIITHI MW, ABRAHAM WR, ADDAE-KYEREME J, SCOWEN I, CROF SL, GITU PM, KENDRICK HENM AND WRIGHT CW. 2002. Isolation and in vitro antiplasmodial activities of alkaloids from Teclea trichocarpa: in vivo antimalarial activity and X-ray crystal structure of normelicopicine J Nat Prod 65: 956-959.
    • (2002) J Nat Prod , vol.65 , pp. 956-959
    • Mauriithi, M.W.1    Abraham, W.R.2    Scowen, I.3    Crof, S.L.4    Gitu, P.M.5    Kendrick, H.E.N.M.6    Wright, C.W.7
  • 57
    • 0142216387 scopus 로고    scopus 로고
    • Quinoline, quinazoline and acridone alkaloids
    • MICHAEL JP. 2003. Quinoline, quinazoline and acridone alkaloids. Nat Prod Rep 20: 476-493.
    • (2003) Nat Prod Rep , vol.20 , pp. 476-493
    • Michael, J.P.1
  • 58
    • 0030808505 scopus 로고    scopus 로고
    • Traditional antimalarial medicine in Roraima
    • MILLIKEN W. 1997. Traditional antimalarial medicine in Roraima, Brazil. Econ Bot 51: 212-237.
    • (1997) Brazil. Econ Bot , vol.51 , pp. 212-237
    • Milliken, W.1
  • 59
    • 0003266485 scopus 로고    scopus 로고
    • The use of medicinal plants by the Yanomami Indians of Brazil
    • MILLIKEN W AND ALBERT B. 1996. The use of medicinal plants by the Yanomami Indians of Brazil. Econ Bot 50: 10-25.
    • (1996) Econ Bot , vol.50 , pp. 10-25
    • Milliken, W.1    Albert, B.2
  • 60
    • 0030845237 scopus 로고    scopus 로고
    • The use of medicinal plants by the Yanomami Indians of Brazil, Part II
    • MILLIKEN W AND ALBERT B. 1997. The use of medicinal plants by the Yanomami Indians of Brazil, Part II. Econ Bot 51: 264-278.
    • (1997) Econ Bot , vol.51 , pp. 264-278
    • Milliken, W.1    Albert, B.2
  • 61
    • 0036216921 scopus 로고    scopus 로고
    • Antiplasmodial activity of Aspidosperma indole alkaloids
    • MITAINE-OFFER AC, SAUVAIN M, VALENTIN A, CALLAPA J, MALLIÉ M AND ZÈCHES-HANROT M. 2002. Antiplasmodial activity of Aspidosperma indole alkaloids. Phytomedicine 9: 142-145.
    • (2002) Phytomedicine , vol.9 , pp. 142-145
    • Sauvain, M.1    Valentin, A.2    Callapa, J.3    Mallié, M.4
  • 64
    • 34250322702 scopus 로고    scopus 로고
    • In vivo antimalarial activity of isosungucine, an indolomonoterpenic alkaloid from Strychnos icaja
    • PHILIPPE G, DE MOL P, ANGENOT L, TITS M AND FREDERICH M. 2007. In vivo antimalarial activity of isosungucine, an indolomonoterpenic alkaloid from Strychnos icaja. Planta Med 73: 478-479.
    • (2007) Planta Med , vol.73 , pp. 478-479
    • Philippe, G.1    de Mol, P.2    Angenot, L.3    Tits, M.4    Frederich, M.5
  • 66
    • 4143105902 scopus 로고    scopus 로고
    • Three new species of Galipea (Rutaceae, Galipeinae) from Brazil
    • PIRANI JR. 2004. Three new species of Galipea (Rutaceae, Galipeinae) from Brazil. Bot J Linnean Soc 144: 365-373.
    • (2004) Bot J Linnean Soc , vol.144 , pp. 365-373
    • Pirani, J.R.1
  • 67
    • 33751269892 scopus 로고    scopus 로고
    • An improved and highly sensitive microfluorimetric method for assessing suceptibility of Plasmodium falciparum to antimalarial drugs in vitro
    • QUASHIE NB, KONING HP AND RANFORD-CARTWRIGH LC. 2006. An improved and highly sensitive microfluorimetric method for assessing suceptibility of Plasmodium falciparum to antimalarial drugs in vitro. Malaria J 5: 95-101.
    • (2006) Malaria J , vol.5 , pp. 95-101
    • Quashie, N.B.1    Koning, H.P.2
  • 68
    • 65549153498 scopus 로고    scopus 로고
    • Modern approaches in the search for new lead antiparasiticcompoundsfromhigherplants
    • QUEIROZ EF, WOLFENDER JL AND HOSTETTMANN K. 2009. Modern approaches in the search for new lead antiparasiticcompoundsfromhigherplants. CurrDrugsTargets 10: 202-211.
    • (2009) CurrDrugsTargets , vol.10 , pp. 202-211
    • Queiroz, E.F.1    Wolfender, J.L.2    Hostettmann, K.3
  • 71
    • 85087574681 scopus 로고    scopus 로고
    • Antimalarial chemotherapy: Mechanisms of action, resistence and new directions in drug discovery
    • ROSENTHAL PJ. 2001. Antimalarial chemotherapy: mechanisms of action, resistence and new directions in drug discovery. Mem Inst Oswaldo Cruz 96: 1185-186.
    • (2001) Mem Inst Oswaldo Cruz , vol.96 , pp. 1185-1186
    • Rosenthal, P.J.1
  • 72
    • 0242406992 scopus 로고    scopus 로고
    • Antimalarial drug discovery: Old and new approaches
    • ROSENTHAL PJ. 2003. Antimalarial drug discovery: old and new approaches. J Exp Biol 206: 3735-3744.
    • (2003) J Exp Biol , vol.206 , pp. 3735-3744
    • Rosenthal, P.J.1
  • 73
    • 70449449453 scopus 로고    scopus 로고
    • Validation of a Plasmodium falciparum parasite transformed with green fluorescent protein for antimalarial drug screening
    • SANCHEZ BAM, VAROTTI FP, RODRIGUES FG AND CARVALHO LH. 2007. Validation of a Plasmodium falciparum parasite transformed with green fluorescent protein for antimalarial drug screening. J Microbiological Methods 20: 1-5.
    • (2007) J Microbiological Methods , vol.20 , pp. 1-5
    • Sanchez, B.A.M.1    Varotti, F.P.2    Rodrigues, F.G.3    Carvalho, L.H.4
  • 75
    • 0036919713 scopus 로고    scopus 로고
    • Antimalarial activity of plant metabolites
    • SCHWIKKARD S AND VAN HEERDEN FR. 2002. Antimalarial activity of plant metabolites. Nat Prod Report 19: 675-692.
    • (2002) Nat Prod Report , vol.19 , pp. 675-692
    • Schwikkard, S.1    van Heerden, F.R.2
  • 76
    • 0000618778 scopus 로고    scopus 로고
    • Conformational analysis of the antimalarial agent qui-nine
    • SILVA THA, OLIVEIRA AB AND ALMEIDA WB. 1997. Conformational analysis of the antimalarial agent qui-nine. Structural Chem 8: 95-107.
    • (1997) Structural Chem , vol.8 , pp. 95-107
    • Silva, T.H.A.1    Oliveira, A.B.2    Almeida, W.B.3
  • 78
    • 18344391887 scopus 로고    scopus 로고
    • Molecular modeling study of complexes between ferriprotoporphyrin IX and anti-malarial 4-quinolinecarbinolamines: A proposal of pharmacophore
    • SILVA THA, OLIVEIRA MT, SANTOS HF, OLIVEIRA AB AND ALMEIDA WB. 2005. Molecular modeling study of complexes between ferriprotoporphyrin IX and anti-malarial 4-quinolinecarbinolamines: a proposal of pharmacophore. Química Nova 28: 244-249.
    • (2005) Química Nova , vol.28 , pp. 244-249
    • Silva, T.H.A.1    Oliveira, M.T.2    Santos, H.F.3    Oliveira, A.B.4    Almeida, W.B.5
  • 80
    • 0037021386 scopus 로고    scopus 로고
    • Theories on malarial pigment formation and quinoline action
    • SULLIVAN DJ. 2002. Theories on malarial pigment formation and quinoline action. Int J Parasitol 32: 1645-1653.
    • (2002) Int J Parasitol , vol.32 , pp. 1645-1653
    • Sullivan, D.J.1
  • 81
    • 0035179157 scopus 로고    scopus 로고
    • Antiparasitic properties of medicinal plants and other naturally occurring products
    • TAGBOTO S AND TOWNSON S. 2001. Antiparasitic properties of medicinal plants and other naturally occurring products. Advances in Parasitol 50: 199-295.
    • (2001) Advances in Parasitol , vol.50 , pp. 199-295
    • Tagboto, S.1    Townson, S.2
  • 82
    • 55449088864 scopus 로고    scopus 로고
    • Evaluation of a new strategy in the malaria control in the Brazilian Amazon
    • TAUIL PL. 2003. Evaluation of a new strategy in the malaria control in the Brazilian Amazon. Rev Inst Med Trop São Paulo 45: 306.
    • (2003) Rev Inst Med Trop São Paulo , vol.45 , pp. 306
    • Tauil, P.L.1
  • 83
    • 0017311840 scopus 로고
    • Human malaria parasites in continuous culture
    • TRAGER W AND JENSEN JB. 1976. Human malaria parasites in continuous culture. Science 193: 673-675.
    • (1976) Science , vol.193 , pp. 673-675
    • Trager, W.1    Jensen, J.B.2
  • 84
    • 0019845594 scopus 로고
    • The quinine-haemin interaction and its relationship to antimalarial activity
    • WARHURST DC. 1981. The quinine-haemin interaction and its relationship to antimalarial activity. Biochem Pharmacol 30: 3323-3327.
    • (1981) Biochem Pharmacol , vol.30 , pp. 3323-3327
    • Warhurst, D.C.1
  • 85
    • 0033151364 scopus 로고    scopus 로고
    • The chemical systematics of alkaloids: A review emphasising the contribution of Robert Hegnauer
    • WATERMAN PG. 1999. The chemical systematics of alkaloids: A review emphasising the contribution of Robert Hegnauer. Biochem System Ecol 27: 395-406.
    • (1999) Biochem System Ecol , vol.27 , pp. 395-406
    • Waterman, P.G.1
  • 87
    • 27944474130 scopus 로고    scopus 로고
    • WHO., Geneva, World Health Organization
    • WHO. 2005. World Malaria Report. Geneva, World Health Organization, http://rbm.who.int/wmr.2005.
    • (2005) World Malaria Report
  • 88
    • 27944474130 scopus 로고    scopus 로고
    • WHO., Geneva, World Health Organization
    • WHO. 2008. World Malaria Report. Geneva, World Health Organization. http://rbm.who.int/wmr.2008.
    • (2008) World Malaria Report
  • 89
    • 8744257799 scopus 로고    scopus 로고
    • Traditional herbal medicines for malaria
    • WILLCOX ML AND BODEKER G. 2004. Traditional herbal medicines for malaria. Brit Med J 329: 1156-1159.
    • (2004) Brit Med J , vol.329 , pp. 1156-1159
    • Willcox, M.L.1    Bodeker, G.2
  • 91
    • 23944454585 scopus 로고    scopus 로고
    • Plant derived antimalarial agents: New leads and challenges
    • WRIGHT CW. 2005a. Plant derived antimalarial agents: New leads and challenges. Phytochem Rev 4: 55-61.
    • (2005) Phytochem Rev , vol.4 , pp. 55-61
    • Wright, C.W.1
  • 92
    • 23044507928 scopus 로고    scopus 로고
    • Traditional antimalarial and the development of novel antimalarial drugs
    • WRIGHT CW. 2005b. Traditional antimalarial and the development of novel antimalarial drugs. J Ethnopharmacol 100: 67-71.
    • (2005) J Ethnopharmacol , vol.100 , pp. 67-71
    • Wright, C.W.1


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