Determination of dependencies among in vitro and in vivo properties of prepared mucoadhesive buccal films using multivariate data analysis

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 86, Issue 3, 2014, Pages 498-506

  Vetchý, David ^a   Landová, Hana ^a   Gajdziok, Jan ^a   Doležel, Petr ^a   Daněk, Zdeněk ^b   Štembírek, Jan ^c  

^a UNIVERSITY OF VETERINARY AND PHARMACEUTICAL SCIENCES   (Czech Republic)

^b UNIVERSITY HOSPITAL BRNO   (Czech Republic)

^c UNIVERSITY HOSPITAL OSTRAVA   (Czech Republic)

Author keywords

Backing layer; Carmellose; In vitro testing; In vivo evaluation; Method of impregnation; Mucoadhesive buccal films; Multivariate data analysis; Non woven textile; Residence time; Solvent casting method

Indexed keywords

CARBOXYMETHYLCELLULOSE; ETHYL CELLULOSE; MACROGOL; PROPOLIS; SOLVENT; WHITE PETROLATUM; ADHESIVE AGENT;

ARTICLE; DRUG COATING; DRUG DOSAGE FORM; DRUG FORMULATION; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MUCOADHESIVE BUCCAL FILM; NORMAL HUMAN; PARTIAL LEAST SQUARES REGRESSION; PRINCIPAL COMPONENT ANALYSIS; ADHESION; ADULT; AGED; BUCCAL DRUG ADMINISTRATION; CHEMISTRY; DRUG EFFECTS; FEMALE; MALE; MEDICINAL CHEMISTRY; METABOLISM; MIDDLE AGED; MOUTH MUCOSA; MULTIVARIATE ANALYSIS; VERY ELDERLY; YOUNG ADULT;

ADHESIVENESS; ADHESIVES; ADMINISTRATION, BUCCAL; ADULT; AGED; AGED, 80 AND OVER; CARBOXYMETHYLCELLULOSE SODIUM; CHEMISTRY, PHARMACEUTICAL; FEMALE; HUMANS; MALE; MIDDLE AGED; MOUTH MUCOSA; MULTIVARIATE ANALYSIS; YOUNG ADULT;

EID: 84898439250     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2013.12.002     Document Type: Article

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