Tailoring cytotoxicity of antimicrobial peptidomimetics with high activity against multidrug-resistant Escherichia coli

Journal of Medicinal Chemistry

Volumn 57, Issue 7, 2014, Pages 2864-2873

  Jahnsen, Rasmus D ^a   Sandberg Schaal, Anne ^b   Vissing, Karina Juul ^a   Nielsen, Hanne Mørck ^a   Frimodt Møller, Niels ^b   Franzyk, Henrik ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b HVIDOVRE HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

CEFOTAXIME; GENTAMICIN; OLIGOMER; PEPTIDOMIMETIC AGENT; PEPTOID; VANCOMYCIN;

ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL VIABILITY; CHIRALITY; CIRCULAR DICHROISM; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ESCHERICHIA COLI; FEMALE; HEMOLYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; MAMMAL CELL; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANCE; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE;

ANTI-BACTERIAL AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; ANTINEOPLASTIC AGENTS; CELL PROLIFERATION; CIRCULAR DICHROISM; DRUG RESISTANCE, MULTIPLE; GRAM-NEGATIVE BACTERIA; HUMANS; LIPOSOMES; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; NEOPLASMS; PEPTIDOMIMETICS; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 84898432553     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm401335p     Document Type: Article

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