Substitution of the leucine zipper sequence in melittin with peptoid residues affects self-association, cell selectivity, and mode of action

Biochimica et Biophysica Acta - Biomembranes

Volumn 1768, Issue 6, 2007, Pages 1506-1517

  Zhu, Wan Long ^a   Song, Yun Mi ^a   Park, Yoonkyung ^a,b   Park, Ka Hyon ^a   Yang, Sung Tae ^c   Kim, Jae Il ^c   Park, Il Seon ^a,d   Hahm, Kyung Soo ^a,d   Shin, Song Yub ^a,d  

^a Chosun University   (South Korea)

^b Chosun University   (South Korea)

^c Gwangju Institute of Science and Technology (GIST)   (South Korea)

^d Chosun University College of Medicine   (South Korea)

Author keywords

Antimicrobial peptide; Cell selectivity; Leucine zipper; Melittin; Peptoid residue; Self association

Indexed keywords

ALANINE; AMPHOLYTE; DODECYL SULFATE SODIUM; LEUCINE; LYSINE; MELITTIN; PEPTOID; PHENYLALANINE; POLYPEPTIDE ANTIBIOTIC AGENT;

ALPHA HELIX; AMINO ACID SUBSTITUTION; ANIMAL CELL; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL CELL; CELL INTERACTION; CELL MEMBRANE DEPOLARIZATION; CELL MEMBRANE POTENTIAL; CIRCULAR DICHROISM; CONTROLLED STUDY; CYTOTOXICITY; DRUG SELECTIVITY; FEMALE; HUMAN; HUMAN CELL; MAMMAL CELL; MEMBRANE DAMAGE; MICELLE; MOUSE; NONHUMAN; PHOSPHOLIPID VESICLE; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN STRUCTURE; UTERINE CERVIX CANCER;

AMINO ACID SEQUENCE; AMINO ACIDS; ANIMALS; BACTERIA; CELL MEMBRANE; CIRCULAR DICHROISM; ERYTHROCYTES; HELA CELLS; HUMANS; LEUCINE ZIPPERS; MELITTEN; MOLECULAR SEQUENCE DATA; PEPTOIDS; PROTEIN ENGINEERING; PROTEIN STRUCTURE, SECONDARY; TETRAZOLIUM SALTS; THIAZOLES;

BACTERIA (MICROORGANISMS); MAMMALIA; NALA;

EID: 34249070808     PISSN: 00052736     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamem.2007.03.010     Document Type: Article

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