Membrane adsorption and binding, cellular uptake and cytotoxicity of cell-penetrating peptidomimetics with α-peptide/β-peptoid backbone: Effects of hydrogen bonding and α-chirality in the β-peptoid residues

Biochimica et Biophysica Acta - Biomembranes

Volumn 1818, Issue 11, 2012, Pages 2660-2668

  Jing, Xiaona ^a   Yang, Mingjun ^b   Kasimova, Marina R ^a   Malmsten, Martin ^c   Franzyk, Henrik ^a   Jorgensen, Lene ^a   Foged, Camilla ^a   Nielsen, Hanne M ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c UPPSALA UNIVERSITY   (Sweden)

Author keywords

Adsorption; Binding constant; Cell penetrating peptide; Chirality; Hydrogen bonding; Peptidomimetic

Indexed keywords

ALPHA AMINO ACID; ALPHA PEPTIDE; BETA PEPTOID; CELL PENETRATING PEPTIDE; GUANIDINE; PEPTIDOMIMETIC AGENT; UNCLASSIFIED DRUG;

ADSORPTION KINETICS; ARTICLE; BINDING AFFINITY; BINDING SITE; CELL TRANSPORT; CELL VIABILITY; CHIRALITY; CIRCULAR DICHROISM; CONTROLLED STUDY; CYTOTOXICITY; DIFFUSION; ELLIPSOMETRY; HYDROGEN BOND; LIPID BILAYER; MEMBRANE BINDING; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR SIZE; PRIORITY JOURNAL; RESIDUE ANALYSIS; SURFACE PROPERTY;

ADSORPTION; CALORIMETRY; CIRCULAR DICHROISM; HELA CELLS; HUMANS; HYDROGEN BONDING; LIPOSOMES; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; PEPTIDOMIMETICS; PEPTOIDS; PROTEIN BINDING; STEREOISOMERISM;

EID: 84864065351     PISSN: 00052736     EISSN: 18792642     Source Type: Journal    
DOI: 10.1016/j.bbamem.2012.05.003     Document Type: Article

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