Human lactate dehydrogenase A inhibitors: A molecular dynamics investigation

PLoS ONE

Volumn 9, Issue 1, 2014, Pages

  Shi, Yun ^a   Pinto, B Mario ^a  

^a SIMON FRASER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITOR; LACTATE DEHYDROGENASE; LACTATE DEHYDROGENASE A INHIBITOR; LACTATE DEHYDROGENASE ISOENZYME 5; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; COMPUTER MODEL; DRUG BINDING; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME STRUCTURE; FERMENTATION; GLYCOLYSIS; LIGAND BINDING; MOLECULAR DYNAMICS; X RAY CRYSTALLOGRAPHY;

BINDING SITES; ENZYME INHIBITORS; HUMANS; ISOENZYMES; KINETICS; L-LACTATE DEHYDROGENASE; LIGANDS; MOLECULAR DYNAMICS SIMULATION; PROTEIN STRUCTURE, SECONDARY; SUBSTRATE SPECIFICITY; THERMODYNAMICS;

EID: 84898407135     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0086365     Document Type: Article

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