Biochanin A and prunetin improve epithelial barrier function in intestinal CaCo-2 cells via downregulation of ERK, NF-κB, and tyrosine phosphorylation

Free Radical Biology and Medicine

Volumn 70, Issue , 2014, Pages 255-264

  Piegholdt, Stefanie ^a   Pallauf, Kathrin ^a   Esatbeyoglu, Tuba ^a   Speck, Nancy ^b   Reiss, Karina ^b   Ruddigkeit, Lars ^c   Stocker, Achim ^c   Huebbe, Patricia ^a   Rimbach, Gerald ^a  

^a UNIVERSITY OF KIEL   (Germany)

^b UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^c UNIVERSITY OF BERN   (Switzerland)

Author keywords

Biochanin A; ERK; Intestinal epithelial barrier; Isoflavones; NF B; Prunetin; Tyrosine phosphorylation

Indexed keywords

ANTHOCYANIN; BIOCHANIN A; DAIDZEIN; FORMONONETIN; GENISTEIN; GLYCITEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; ISOFLAVONOID; ISORHAMNETIN; MITOGEN ACTIVATED PROTEIN KINASE; OROBOL; PROTEIN TYROSINE KINASE; PRUNETIN; QUERCETIN; TUMOR NECROSIS FACTOR ALPHA; ISOFLAVONE DERIVATIVE; TYROSINE;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL STRAIN CACO 2; CONTROLLED STUDY; ELECTRIC RESISTANCE; HUMAN; HUMAN CELL; INTESTINE EPITHELIAL BARRIER; INTESTINE EPITHELIUM; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; BIOSYNTHESIS; CACO 2 CELL LINE; DRUG EFFECTS; EPITHELIUM CELL; GENE EXPRESSION REGULATION; INTESTINE MUCOSA; METABOLISM; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

CACO-2 CELLS; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; GENISTEIN; HUMANS; INTESTINAL MUCOSA; ISOFLAVONES; MAP KINASE SIGNALING SYSTEM; NF-KAPPA B; PHOSPHORYLATION; TUMOR NECROSIS FACTOR-ALPHA; TYROSINE;

EID: 84898402102     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2014.02.025     Document Type: Article

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