Activation of protein phosphorylation by oxidants in vascular endothelial cells: Identification of tyrosine phosphorylation of caveolin

Free Radical Biology and Medicine

Volumn 22, Issue 1-2, 1997, Pages 25-35

  Vepa, Suryanarayana ^a   Scribner, William M ^a   Natarajan, Viswanathan ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Caveolae; Caveolin; Endothelial cells; Free radicals; Hydrogen peroxide; Oxidants; Pervanadate; Protein kinases; Protein phosphatases; Protein phosphorylation; Vanadate

Indexed keywords

CAVEOLIN; GENISTEIN; HYDROGEN PEROXIDE; OXIDIZING AGENT; PERVANADATE; PHOSPHATASE; PHOSPHORUS 32; PROTEIN; PROTEIN TYROSINE KINASE; STAUROSPORINE; VANADIC ACID;

ANIMAL CELL; ARTICLE; AUTORADIOGRAPHY; CATTLE; CONTROLLED STUDY; IMMUNOPRECIPITATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PULMONARY ARTERY; VASCULAR ENDOTHELIUM;

ANIMALIA; BOS TAURUS; BOVINAE; TRIXIS;

EID: 0029955451     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(96)00241-9     Document Type: Article

References (40)

1. Birgham K. L. Role of free radicals in lung injury. Chest. 89:1986;859-863.
2. Halliwell B., Gutteridge J. M. C. Free radicals in biology and medicine. 2nd ed. 1989;Oxford University Press, Oxford.
3. Natarajan V. Oxidants and signal transduction in vascular endothelium. J. Lab. Clin. Med. 125:1995;26-37.
4. Wilson J., Winter M., Shasby D. M. Oxidants, ATP depletion and endothelial permeability to macromolecules. Blood. 76:1990;2578-2582.
5. Andreoli S. P., Mallet C. P., Bergstein J. M. Role of glutathione in protecting endothelial cells against hydrogen peroxide oxidant injury. J. Lab. Clin. Med. 108:1986;190-198.
6. ++ signaling mechanisms of vascular endothelial cells and their role in oxidant-induced endothelial cell dysfunction. Am. J. Physiol. 262:1992;H1617-1630.
7. Garcia J. G. N., Natarajan V. Signal transduction in pulmonary endothelium: Implications for lung vascular dysfunction. Chest. 102:1992;592-597.
8. Whisler R. L., Goyette M. A., Grants I. S., Newhouse I. G. Sublethal levels of oxidant stress stimulate multiple serine/threonine kinases and suppress protein phosphatases in Jurkat T cells. Arch. Biochem. Biophys. 319:1995;23-35.
9. Lum H., Malik A. B. Regulation of vascular endothelial barrier function. Am. J. Physiol. 267:1994;L223-L241.
10. Mackie K., Lai Y., Nairn A. C., Greengard P., Pitt B. R., Lazo J. S. Protein phosphorylation in cultured endothelial cells. J. Cell. Physiol. 128:1986;367-374.
11. 2 and vanadate concomitantly stimulates protein tyrosine phosphorylation and polyphosphoinositide break down in different cell lines. Biochemistry. 29:1992;10240-10245.
12. 2 and vanadate in vitro. Biochem. Biophys. Res. Comm. 188:1992;773-779.
13. 2 and vanadate stimulate protein tyrosine phosphorylation in intact cells. J. Biol. Chem. 265:1990;2896-2902.
14. Trudel S., Paquet M. R., Grinstein S. Mechanism of vanadate-induced activation of tyrosine phosphorylation and of the respiratory burst in HL 60 cells. Role of reduced oxygen metabolites. Biochem. J. 276:1991;611-619.
15. Pumiglia K. M., Lau L. F., Huang C.-K., Burroughs S., Feinstein M. B. Activation of signal transduction in platelets by the tyrosine phosphatase inhibitor pervanadate (vanadyl hydroperoxide). Biochem. J. 286:1992;441-449.
16. Posner B. I., Faure R., Burgess J. W., Bevan A. P., Lachance D., Zhang-Sun G., Fantus I. G., Ng J. B., Lum B. S., Shaver A. Peroxovanadium compounds: A new class of potent phosphotyrosine phosphatase inhibitors which are insulin mimetics. J. Biol. Chem. 269:1994;4596-4604.
17. Evans G. A., Garcia G. G., Erwin R., Zack Howard O. M., Farrar W. L. Pervanadate stimulates the effects of Interleukin-2(IL-2) in human T-cells and provides evidence for the activation of two distinct tyrosine kinase pathways by IL-2. J. Biol. Chem. 269:1994;23407-23412.
18. Secrist J. P., Burns L. A., Karnitz L., Koretzky G. A., Abraham R. T. Stimulatory effects of the tyrosine phosphatase inhibitor, Pervanadate, on T cell activation events. J. Biol. Chem. 268:1993;5886-5893.
19. Fialkow L., Chan C. K., Rotin D., Grinstein S., Downey G. P. Activation of the mitogen activated protein kinase signalling pathway in neutrophils: Role of oxidants. J. Biol. Chem. 269:1994;31234-31242.
20. Barchowsky A., Williams M. E., Benz C. C., Chepenik K. P. Oxidant sensitive protein phosphorylation in endothelial cells. Free Radic. Biol. Med. 16:1994;771-777.
21. Natarajan V., Taher M. M., Roehm B., Parinandi N. L., Schmid H. H. O., Garcia J. G. N. Activation of endothelial cell phospholipase D by hydrogen peroxide and fatty acid hydroperoxide. J. Biol. Chem. 268:1993;597-600.
22. Laemmli U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227:1970;680-685.
23. 2 activation: Potentiation by vanadate. Biochem. J. 295:1993;879-888.
24. Bradford M. M. A rapid and sensitive method for quantification of microgram quantities of protein utilizing the principal of protein-dye binding. Anal. Biochem. 72:1976;238-259.
25. Fialkow L., Chan C. K., Grinstein S., Downey G. P. Regulation of tyrosine phosphorylation in neutrophils by the NADPH oxidase: Role of reactive oxygen intermediates. J. Biol. Chem. 268:1993;17131-17137.
26. Zilberman Y., Gutman Y. Multiple effects of staurosporine, a kinase inhibitor, on the thymocyte functions. Comparison with the effect of tyrosine kinase inhibitors. Biochem. Pharmacol. 44:1992;1563-1568.
27. Seger R., Biener R., Feinstein R., Hanoch T., Gazit A., Zick Y. Differential activation of mitogen-activated protein kinase and S6 kinase signalling pathways by 12-O-tetradecanoylphorbol-13-acetate(TPA) and Insulin: Evidence for involvement of a TPA-stimulated protein tyrosine kinase. J. Biol. Chem. 270:1995;28325-28330.
28. Glenny J. R., Soppet D. Sequence and expression of caveolin, a protein component of caveolae plasma membrane domains phosphorylated on tyrosine in RSV-transformed fibroblasts. Proc. Natl. Acad. Sci. USA. 89:1992;10517-10521.
29. Rothberg K. G., Heuser J. E., Donzell W. C., Ying Y- S., Glenny J. R., Anderson R. G. W. Caveolin, a protein component of caveolae membrane coats. Cell. 68:1992;673-682.
30. Anderson R. G. W., Kamen B. A., Rothberg K. G., Lacey S. W. Potocytosis: Sequestration and transport of small molecules by caveolae. Science. 255:1992;410-411.
31. Anderson R. G. W. Caveolae: Where incoming and out going messengers meet. Proc. Natl. Acad. Sci. USA. 90:1993;10909-10913.
32. Li S., Okamoto T., Chun M., Sargiacomo M., Casanova J. E., Hansen S. H., Nishimoto I., Lisanti M. P. Evidence for a regulated interaction between Heterotrimeric G proteins and Caveolin. J. Biol. Chem. 270:1995;15693-15701.
33. Sargiacomo M., Sudol M., Tang Z. L., Lisanti M. P. Signal transducing molecules and glycosyl-phosphatidylinositol-linked proteins form a caveolin-rich insoluble complex in MDCK cells. J. Cell Biol. 122:1993;789-807.
34. Chun M., Liyanage U. K., Lisanti M. P., Lodish H. F. Signal transduction of a G protein-coupled receptor in caveolae: Colocalization of endothelin and its receptor with caveolin. Proc. Natl. Acad. Sci. USA. 91:1994;11728-11732.
35. Chang W. J., Ying Y. S., Rothberg K. G., Hooper N. M., Turner A. J., Gambliel H. A., Gunzburg J. D., Mumby S. M., Gilman A. G., Anderson R. G. W. Purification and characterization of smooth muscle cell caveolae. J. Cell Biol. 126:1994;127-138.
36. Lisanti M. P., Scherer P. E., Vidugiriene J., Tang Z. L., Hermanowski-Vosatka A., Tu Y- H., Cook R. F., Sargiacomo M. Characterization of Caveolin rich membrane domains from an endothelial rich source: Implications for human disease. J. Cell Biol. 126:1994;111-126.
37. Sargiacomo M., Scherer P. E., Tang Z.- L., Casanova J. E., Lisanti M. P. In vitro phosphorylation of caveolin-rich membrane domains: Identification of an associated serine kinase activity as casein kinase II-like enzyme. Oncogene. 9:1994;2589-2595.
38. Tang Z.-L., Scherer P. E., Lisanti M. P. The primary sequence of murine caveolin reveals a conserved consensus site for phosphorylation by protein kinase C. Gene. 147:1994;299-300.
39. Madsen K. L., Porter V. M., Fedorak R. N. Vanadate reduces sodium-dependent glucose transport and increases glycolytic activity in LLC-Pk1 epithelia. J. Cell. Physiol. 158:1994;459-466.
40. Huot J., Lambert H., Lavoie J. N., Guimond A., Houle F., Landry J. Characterization of 45 kDa/54K-Da HSP27 kinase, a stress-sensitive kinase which may activate the phosphorylation-dependent protective function of mammalian 27 kDa heat-shock protein HSP27. Eur. J. Biochem. 227:1995;416-427.