High oxygen condition facilitates the differentiation of mouse and human pluripotent stem cells into pancreatic progenitors and insulin-producing cells

Journal of Biological Chemistry

Volumn 289, Issue 14, 2014, Pages 9623-9638

  Hakim, Farzana ^a,b   Kaitsuka, Taku ^a   Raeed, Jamiruddin Mohd ^a   Wei, Fan Yan ^a   Shiraki, Nobuaki ^a   Akagi, Tadayuki ^b   Yokota, Takashi ^b   Kume, Shoen ^a   Tomizawa, Kazuhito ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

^b KANAZAWA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GENE EXPRESSION; INSULIN; MAMMALS; OXYGEN; STEM CELLS;

EMBRYONIC DEVELOPMENT; HYPOXIA-INDUCIBLE FACTOR 1; INDUCED PLURIPOTENT STEM CELLS; INSULIN-PRODUCING CELLS; MOUSE EMBRYONIC STEM CELLS; PARTIAL PRESSURE OF OXYGEN; PLURIPOTENT STEM CELLS; REGENERATIVE MEDICINE;

CYTOLOGY;

C PEPTIDE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; NEUROGENIN 3; OXYGEN; TRANSCRIPTION FACTOR HES 1;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; EMBRYONIC STEM CELL; GENE EXPRESSION; HES1 GENE; HUMAN; HUMAN CELL; INSULIN SYNTHESIS; MOUSE; NGN3 GENE; NONHUMAN; NOTCH SIGNALING; PANCREAS ISLET BETA CELL; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; WNT SIGNALING PATHWAY;

DIFFERENTIATION; EMBRYONIC STEM CELL; HYPOXIA-INDUCIBLE FACTOR; INDUCED PLURIPOTENT STEM CELLS; REGENERATIVE MEDICINE;

ANIMALS; CELL DIFFERENTIATION; CELL LINE; EMBRYONIC STEM CELLS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INSULIN; INSULIN-SECRETING CELLS; MICE; OXYGEN; PLURIPOTENT STEM CELLS;

EID: 84898081496     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.524363     Document Type: Article

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