Exposure to an organophosphate pesticide, individually or in combination with other Gulf War agents, impairs synaptic integrity and neuronal differentiation, and is accompanied by subtle microvascular injury in a mouse model of Gulf War agent exposure

Neuropathology

Volumn 34, Issue 2, 2014, Pages 109-127

  Ojo, Joseph O ^a   Abdullah, Laila ^a   Evans, James ^a   Reed, Jon Mike ^a   Montague, Hannah ^a   Mullan, Michael J ^a   Crawford, Fiona C ^a  

^a ROSKAMP INSTITUTE   (United States)

Author keywords

Astrocytes; Gulf war illness (GWI); Microglia; Microvessels; Neurogenesis; Synapses

Indexed keywords

ACETYLCHOLINE; CD31 ANTIGEN; CHLORPYRIFOS; COLLAGEN TYPE 4; DIMETHYL SULFOXIDE; DOUBLECORTIN; ORGANOPHOSPHATE PESTICIDE; SYNAPTOPHYSIN; CHEMICAL WARFARE AGENT; INSECTICIDE; ORGANOPHOSPHATE;

ACETYLCHOLINE BRAIN LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BASOLATERAL AMYGDALA; BLOOD VESSEL INJURY; BRAIN HOMOGENATE; CELL ACTIVATION; CELL COUNT; CHROMATIN CONDENSATION; CONTROLLED STUDY; DENTATE GYRUS; ENDOTHELIUM CELL; EXPOSURE; HIPPOCAMPAL CA3 REGION; HIPPOCAMPUS; IMMUNOCOMPETENT CELL; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; MICROGLIA; MOTOR CORTEX; MOUSE; NERVE CELL DIFFERENTIATION; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PYRIFORM CORTEX; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; SUBTLE MICROVASCULAR INJURY; SYNAPSE; WAR; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; CAPILLARY; CELL DIFFERENTIATION; DISEASE MODEL; DRUG EFFECTS; HUMAN; METABOLISM; NERVE CELL; PATHOLOGY; PERSIAN GULF SYNDROME; TOXICITY;

ACETYLCHOLINE; ANIMALS; CAPILLARIES; CELL DIFFERENTIATION; CHEMICAL WARFARE AGENTS; DISEASE MODELS, ANIMAL; GULF WAR; HUMANS; INSECTICIDES; MICE; MICE, INBRED C57BL; NEURONS; ORGANOPHOSPHATES; PERSIAN GULF SYNDROME; SYNAPSES;

EID: 84898058367     PISSN: 09196544     EISSN: 14401789     Source Type: Journal    
DOI: 10.1111/neup.12061     Document Type: Article

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