메뉴 건너뛰기




Volumn 38, Issue 12, 2013, Pages 2348-2362

Mood and memory deficits in a model of gulf war illness are linked with reduced neurogenesis, partial neuron loss, and mild inflammation in the hippocampus

Author keywords

adult neurogenesis; anxiety; depression; learning and memory; mood; neuroinflammation

Indexed keywords

DIETHYLTOLUAMIDE; PERMETHRIN; PYRIDOSTIGMINE;

EID: 84888354773     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2013.158     Document Type: Article
Times cited : (154)

References (67)
  • 1
    • 0036407359 scopus 로고    scopus 로고
    • Disruption of the blood-brain barrier and neuronal cell death in cingulate cortex, dentate gyrus, thalamus, and hypothalamus in a rat model of Gulf-War syndrome
    • DOI 10.1006/nbdi.2002.0524
    • AbDEl-Rahman A, Shetty AK, Abou-Donia MB (2002). Disruption of the blood-brain barrier and neuronal cell DEath in cingulate cortex, DEntate gyrus, thalamus, and hypothalamus in a rat moDEl of Gulf-War syndrome. Neurobiol Dis 10: 306-326. (Pubitemid 35217583)
    • (2002) Neurobiology of Disease , vol.10 , Issue.3 , pp. 306-326
    • Abdel-Rahman, A.1    Shetty, A.K.2    Abou-Donia, M.B.3
  • 2
    • 1642535576 scopus 로고    scopus 로고
    • Stress and combined exposure to low doses of pyridostigmine bromide, deet, and permethrin produce neurochemical and neuropathological alterations in cerebral cortex, hippocampus, and cerebellum
    • AbDEl-Rahman A, Abou-Donia S, El-Masry E, Shetty A, Abou-Donia M (2004a). Stress and combined exposure to low doses of PB, DEET, and permethrin produce neurochemical and neuropathological alterations in cerebral cortex, hippocampus, and cerebellum. J Toxicol Environ Health A 67: 163-192. (Pubitemid 38124498)
    • (2004) Journal of Toxicology and Environmental Health - Part A , vol.67 , Issue.2 , pp. 163-192
    • Abdel-Rahman, A.1    Abou-Donia, S.M.2    El-Masry, E.M.3    Shetty, A.K.4    Abou-Donia, M.B.5
  • 3
    • 4644239350 scopus 로고    scopus 로고
    • Nestin expression in hippocampal astrocytes after injury depends on the age of the hippocampus
    • DOI 10.1002/glia.20047
    • AbDEl-Rahman A, Rao MS, Shetty AK (2004b). Nestin expression in hippocampal astrocytes after injury DEpends on the age. Glia 47: 299-313. (Pubitemid 39295414)
    • (2004) GLIA , vol.47 , Issue.4 , pp. 299-313
    • Abdel-Rahman, A.1    Rao, M.S.2    Shetty, A.K.3
  • 4
    • 84855871618 scopus 로고    scopus 로고
    • Proteomic CNS profile of DElayed cognitive impairment in mice exposed to Gulf War agents
    • Abdullah L, Crynen G, Reed J, Bishop A, Phillips J, Ferguson S et al (2011). Proteomic CNS profile of DElayed cognitive impairment in mice exposed to Gulf War agents. Neuromolecular Med 13: 275-288.
    • (2011) Neuromolecular Med , vol.13 , pp. 275-288
    • Abdullah, L.1    Crynen, G.2    Reed, J.3    Bishop, A.4    Phillips, J.5    Ferguson, S.6
  • 5
    • 84870555767 scopus 로고    scopus 로고
    • Lipidomic profiling of phosphocholine containing brain lipids in mice with sensorimotor DEficits and anxiety-like features after exposure to gulf war agents
    • Abdullah L, Evans JE, Bishop A, Reed JM, Crynen G, Phillips J et al (2012). Lipidomic profiling of phosphocholine containing brain lipids in mice with sensorimotor DEficits and anxiety-like features after exposure to gulf war agents. Neuromolecular Med 14: 349-361.
    • (2012) Neuromolecular Med , vol.14 , pp. 349-361
    • Abdullah, L.1    Evans, J.E.2    Bishop, A.3    Reed, J.M.4    Crynen, G.5    Phillips, J.6
  • 6
    • 0035971576 scopus 로고    scopus 로고
    • Induction of urinary excretion of 3-nitrotyrosine, a marker of oxidative stress, following administration of pyridostigmine bromide, DEET (N,N-diethyl-m-toluamide) and permethrin, alone and in combination in rats
    • DOI 10.1016/S0378-4274(01)00330-7, PII S0378427401003307
    • Abu-Qare W, Suliman HB, Abou-Donia MB (2001). Induction of urinary excretion of 3-nitrotyrosine, a marker of oxidative stress, following administration of pyridostigmine bromiDE, DEET (N,N-diethyl-m-toluamiDE) and permethrin, alone and in combination in rats. Toxicol Lett 121: 127-134. (Pubitemid 32452196)
    • (2001) Toxicology Letters , vol.121 , Issue.2 , pp. 127-134
    • Abu-Qare, A.W.1    Suliman, H.B.2    Abou-Donia, M.B.3
  • 8
    • 79952037223 scopus 로고    scopus 로고
    • Hippocampal volume differences in Gulf War veterans with current versus lifetime posttraumatic stress disorDEr symptoms
    • Apfel BA, Ross J, Hlavin J, Meyerhoff DJ, Metzler TJ, Marmar CR et al (2011). Hippocampal volume differences in Gulf War veterans with current versus lifetime posttraumatic stress disorDEr symptoms. Biol Psychiatry 69: 541-548.
    • (2011) Biol Psychiatry , vol.69 , pp. 541-548
    • Apfel, B.A.1    Ross, J.2    Hlavin, J.3    Meyerhoff, D.J.4    Metzler, T.J.5    Marmar, C.R.6
  • 9
    • 84860720071 scopus 로고    scopus 로고
    • A lifespan approach to neuroinflammatory and cognitive disorDErs: A critical role of glia
    • Bilbo SD, Smith SH, Schwarz JM (2012). A lifespan approach to neuroinflammatory and cognitive disorDErs: a critical role of glia. J Neuroimmune Pharmacol 7: 24-41.
    • (2012) J Neuroimmune Pharmacol , vol.7 , pp. 24-41
    • Bilbo, S.D.1    Smith, S.H.2    Schwarz, J.M.3
  • 11
    • 13844257516 scopus 로고    scopus 로고
    • Neurogenesis in a rat model of age-related cognitive decline
    • DOI 10.1111/j.1474-9728.2004.00099.x
    • Bizon JL, Lee HJ, Gallagher M (2004). Neurogenesis in a rat moDEl of age-related cognitive DEcline. Aging Cell 3: 227-234. (Pubitemid 40246687)
    • (2004) Aging Cell , vol.3 , Issue.4 , pp. 227-234
    • Bizon, J.L.1    Lee, H.J.2    Gallagher, M.3
  • 14
    • 0034214170 scopus 로고    scopus 로고
    • Acute effects of an insect repellent, N,N-diethyl-m-toluamide, on cholinesterase inhibition induced by pyridostigmine bromide in rats
    • DOI 10.1006/taap.2000.8936
    • Chaney LA, Wineman RW, Rockhold RW, Hume AS (2000). Acute effects of an insect repellent, N,N-diethyl-m-toluamiDE, on cholinesterase inhibition induced by pyridostigmine bromiDE in rats. Toxicol Appl Pharmacol 165: 107-114. (Pubitemid 30395360)
    • (2000) Toxicology and Applied Pharmacology , vol.165 , Issue.2 , pp. 107-114
    • Chaney, L.A.1    Wineman, R.W.2    Rockhold, R.W.3    Hume, A.S.4
  • 15
    • 70350026643 scopus 로고    scopus 로고
    • EviDEnce for inhibition of cholinesterases in insect and mammalian nervous systems by the insect repellent DEET
    • Corbel V, Stankiewicz M, Pennetier C, Fournier D, Stojan J, Girard E et al (2009). EviDEnce for inhibition of cholinesterases in insect and mammalian nervous systems by the insect repellent DEET. BMC Biol 7: 47.
    • (2009) BMC Biol , vol.7 , pp. 47
    • Corbel, V.1    Stankiewicz, M.2    Pennetier, C.3    Fournier, D.4    Stojan, J.5    Girard, E.6
  • 16
    • 0036855882 scopus 로고    scopus 로고
    • Cognitive functioning and disturbances of mood in UK veterans of the Persian Gulf War: A comparative study
    • DOI 10.1017/S0033291702006359
    • David AS, Farrin L, Hull L, Unwin C, Wessely S, Wykes T (2002). Cognitive functioning and disturbances of mood in UK veterans of the Persian Gulf War: a comparative study. Psychol Med 32: 1357-1370. (Pubitemid 35385647)
    • (2002) Psychological Medicine , vol.32 , Issue.8 , pp. 1357-1370
    • David, A.S.1    Farrin, L.2    Hull, L.3    Unwin, C.4    Wessely, S.5    Wykes, T.6
  • 17
    • 65649125633 scopus 로고    scopus 로고
    • Neurogenesis-DEpenDEnt and-inDEpenDEnt effects of fluoxetine in an animal moDEl of anxiety/DEpression
    • David DJ, Samuels BA, Rainer Q, Wang JW, Marsteller D, MenDEz I et al (2009). Neurogenesis-DEpenDEnt and-inDEpenDEnt effects of fluoxetine in an animal moDEl of anxiety/DEpression. Neuron 62: 479-493.
    • (2009) Neuron , vol.62 , pp. 479-493
    • David, D.J.1    Samuels, B.A.2    Rainer, Q.3    Wang, J.W.4    Marsteller, D.5    Mendez, I.6
  • 18
    • 77951498581 scopus 로고    scopus 로고
    • New neurons and new memories: How does adult hippocampal neurogenesis affect learning and memory
    • DEng W, Aimone JB, Gage FH (2010). New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory Nat Rev Neurosci 11: 339-350.
    • (2010) Nat Rev Neurosci , vol.11 , pp. 339-350
    • Deng, W.1    Aimone, J.B.2    Gage, F.H.3
  • 22
    • 84867213664 scopus 로고    scopus 로고
    • DEpression and hippocampal neurogenesis: A road to remission
    • Eisch AJ, Petrik D (2012). DEpression and hippocampal neurogenesis: a road to remission Science 338: 72-75.
    • (2012) Science , vol.338 , pp. 72-75
    • Eisch, A.J.1    Petrik, D.2
  • 24
    • 84859608708 scopus 로고    scopus 로고
    • Modifiable factors that alter the size of the hippocampus with ageing
    • Fotuhi M, Do D, Jack C (2012). Modifiable factors that alter the size of the hippocampus with ageing. Nat Rev Neurol 8: 189-202.
    • (2012) Nat Rev Neurol , vol.8 , pp. 189-202
    • Fotuhi, M.1    Do, D.2    Jack, C.3
  • 25
    • 0029850424 scopus 로고    scopus 로고
    • Pyridostigmine brain penetration under stress enhances neuronal excitability and induces early immediate transcriptional response
    • Friedman A, Kaufer D, Shemer J, Hendler I, Soreq H, Tur-Kaspa I (1996). Pyridostigmine brain penetration unDEr stress enhances neuronal excitability and induces early immediate transcriptional response. Nat Med 2: 1382-1385.
    • (1996) Nat Med , vol.2 , pp. 1382-1385
    • Friedman, A.1    Kaufer, D.2    Shemer, J.3    Hendler, I.4    Soreq, H.5    Tur-Kaspa, I.6
  • 27
    • 0031030843 scopus 로고    scopus 로고
    • Self-reported exposure to neurotoxic chemical combinations in the Gulf War: A cross-sectional epidemiologic study
    • Haley RW, Kurt TL (1997). Self-reported exposure to neurotoxic chemical combinations in the Gulf war: a cross-sectional epiDEmiologic study. JAMA 277: 231-237. (Pubitemid 27034270)
    • (1997) Journal of the American Medical Association , vol.277 , Issue.3 , pp. 231-237
    • Haley, R.W.1    Kurt, T.L.2
  • 29
    • 0033824615 scopus 로고    scopus 로고
    • Effect of basal ganglia injury on central dopamine activity in Gulf War syndrome: Correlation of proton magnetic resonance spectroscopy and plasma homovanillic acid levels
    • Haley RW, Fleckenstein JL, Marshall WW, McDonald GG, Kramer GL, Petty F (2000a). Effect of basal ganglia injury on central dopamine activity in Gulf War syndrome: correlation of proton magnetic resonance spectroscopy and plasma homovanillic acid levels. Arch Neurol 57: 1280-1285.
    • (2000) Arch Neurol , vol.57 , pp. 1280-1285
    • Haley, R.W.1    Fleckenstein, J.L.2    Marshall, W.W.3    McDonald, G.G.4    Kramer, G.L.5    Petty, F.6
  • 31
    • 9644289380 scopus 로고    scopus 로고
    • Chronic temporal lobe epilepsy is associated with severely declined dentate neurogenesis in the adult hippocampus
    • DOI 10.1016/j.nbd.2004.08.008, PII S0969996104001895
    • Hattiangady B, Rao MS, Shetty AK (2004). Chronic temporal lobe epilepsy is associated with severely DEclined DEntate neurogenesis in the adult hippocampus. Neurobiol Dis 17: 473-490. (Pubitemid 39574880)
    • (2004) Neurobiology of Disease , vol.17 , Issue.3 , pp. 473-490
    • Hattiangady, B.1    Rao, M.S.2    Shetty, A.K.3
  • 32
    • 36048947606 scopus 로고    scopus 로고
    • Aging does not alter the number or phenotype of putative stem/progenitor cells in the neurogenic region of the hippocampus
    • DOI 10.1016/j.neurobiolaging.2006.09.015, PII S019745800600340X
    • Hattiangady B, Shetty AK (2008). Aging does not alter the number or phenotype of putative stem/progenitor cells in the neurogenic region of the hippocampus. Neurobiol Aging 29: 129-147. (Pubitemid 350102711)
    • (2008) Neurobiology of Aging , vol.29 , Issue.1 , pp. 129-147
    • Hattiangady, B.1    Shetty, A.K.2
  • 33
    • 75149160465 scopus 로고    scopus 로고
    • DEcreased neuronal differentiation of newly generated cells unDErlies diminished neurogenesis in chronic temporal lobe epilepsy
    • Hattiangady B, Shetty AK (2010). DEcreased neuronal differentiation of newly generated cells unDErlies diminished neurogenesis in chronic temporal lobe epilepsy. Hippocampus 20: 97-112.
    • (2010) Hippocampus , vol.20 , pp. 97-112
    • Hattiangady, B.1    Shetty, A.K.2
  • 34
    • 84873049000 scopus 로고    scopus 로고
    • Neural stem cell grafting counteracts hippocampal injury-mediated impairments in mood, memory, and neurogenesis
    • Hattiangady B, Shetty AK (2012). Neural stem cell grafting counteracts hippocampal injury-mediated impairments in mood, memory, and neurogenesis. Stem Cells Transl Med 1: 696-708.
    • (2012) Stem Cells Transl Med , vol.1 , pp. 696-708
    • Hattiangady, B.1    Shetty, A.K.2
  • 35
    • 33747855507 scopus 로고    scopus 로고
    • Individual differences in anxiety trait are related to spatial learning abilities and hippocampal expression of mineralocorticoid receptors
    • DOI 10.1016/j.nlm.2006.02.001, PII S1074742706000244
    • Herrero AI, Sandi C, Venero C (2006). Individual differences in anxiety trait are related to spatial learning abilities and hippocampal expression of mineralocorticoid receptors. Neurobiol Learn Mem 86: 150-159. (Pubitemid 44287574)
    • (2006) Neurobiology of Learning and Memory , vol.86 , Issue.2 , pp. 150-159
    • Herrero, A.I.1    Sandi, C.2    Venero, C.3
  • 36
    • 0030239672 scopus 로고    scopus 로고
    • War Syndromes and Their Evaluation: From the U.S. Civil War to the Persian Gulf War
    • Hyams KC, Wignall FS, Roswell R (1996). War syndromes and their evaluation: from the US Civil War to the Persian Gulf War. Ann Intern Med 125: 398-405. (Pubitemid 126449709)
    • (1996) Annals of Internal Medicine , vol.125 , Issue.5 , pp. 398-405
    • Hyams, K.C.1    Wignall, F.S.2    Roswell, R.3
  • 37
    • 0036325981 scopus 로고    scopus 로고
    • Neuroplasticity in old age: Sustained fivefold induction of hippocampal neurogenesis by long-term environmental enrichment
    • DOI 10.1002/ana.10262
    • Kempermann G, Gast D, Gage FH (2002). Neuroplasticity in old age: sustained fivefold induction of hippocampal neurogenesis by long-term environmental enrichment. Ann Neurol 52: 135-143. (Pubitemid 34810592)
    • (2002) Annals of Neurology , vol.52 , Issue.2 , pp. 135-143
    • Kempermann, G.1    Gast, D.2    Gage, F.H.3
  • 38
    • 84870558067 scopus 로고    scopus 로고
    • Neurogenesis and generalization: A new approach to stratify and treat anxiety disorDErs
    • Kheirbek MA, Klemenhagen KC, Sahay A, Hen R (2012). Neurogenesis and generalization: a new approach to stratify and treat anxiety disorDErs. Nat Neurosci 15: 1613-1620.
    • (2012) Nat Neurosci , vol.15 , pp. 1613-1620
    • Kheirbek, M.A.1    Klemenhagen, K.C.2    Sahay, A.3    Hen, R.4
  • 39
    • 84870740056 scopus 로고    scopus 로고
    • Neurogenesis, inflammation and behavior
    • Kohman RA, RhoDEs JS (2013). Neurogenesis, inflammation and behavior. Brain Behav Immun 27: 22-32.
    • (2013) Brain Behav Immun , vol.27 , pp. 22-32
    • Kohman, R.A.1    Rhodes, J.S.2
  • 41
    • 0035891558 scopus 로고    scopus 로고
    • Reactive oxygen species mediate pyridostigmine-induced neuronal apoptosis: Involvement of muscarinic and NMDA receptors
    • DOI 10.1006/taap.2001.9283
    • Li L, Shou Y, Borowitz JL, Isom GE (2001). Reactive oxygen species mediate pyridostigmine-induced neuronal apoptosis: involvement of muscarinic and NMDA receptors. Toxicol Appl Pharmacol 177: 17-25. (Pubitemid 33135210)
    • (2001) Toxicology and Applied Pharmacology , vol.177 , Issue.1 , pp. 17-25
    • Li, L.1    Shou, Y.2    Borowitz, J.L.3    Isom, G.E.4
  • 43
    • 0034671366 scopus 로고    scopus 로고
    • Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus
    • Malberg JE, Eisch AJ, Nestler EJ, Duman RS (2000). Chronic antiDEpressant treatment increases neurogenesis in adult rat hippocampus. J Neurosci 20: 9104-9110. (Pubitemid 32042912)
    • (2000) Journal of Neuroscience , vol.20 , Issue.24 , pp. 9104-9110
    • Malberg, J.E.1    Eisch, A.J.2    Nestler, E.J.3    Duman, R.S.4
  • 45
    • 2142762959 scopus 로고    scopus 로고
    • Hippocampal dysfunction in Gulf War Syndrome. A proton MR spectroscopy study
    • DOI 10.1016/j.brainres.2004.02.063, PII S000689930400407X
    • Menon PM, Nasrallah HA, Reeves RR, Ali JA (2004). Hippocampal dysfunction in Gulf War Syndrome. A proton MR spectroscopy study. Brain Res 1009: 189-194. (Pubitemid 38553861)
    • (2004) Brain Research , vol.1009 , Issue.1-2 , pp. 189-194
    • Menon, P.M.1    Nasrallah, H.A.2    Reeves, R.R.3    Ali, J.A.4
  • 46
    • 33745684603 scopus 로고    scopus 로고
    • Hippocampal neurogenesis is not required for behavioral effects of environmental enrichment
    • Meshi D, Drew MR, Saxe M, Ansorge MS, David D, Santarelli L et al (2006). Hippocampal neurogenesis is not required for behavioral effects of environmental enrichment. Nat Neurosci 9: 729-731.
    • (2006) Nat Neurosci , vol.9 , pp. 729-731
    • Meshi, D.1    Drew, M.R.2    Saxe, M.3    Ansorge, M.S.4    David, D.5    Santarelli, L.6
  • 47
    • 33344478060 scopus 로고    scopus 로고
    • Lifelong corticosterone level determines age-related decline in neurogenesis and memory
    • DOI 10.1016/j.neurobiolaging.2005.02.014, PII S019745800500103X, Protein Misfolding in Alzheimer's and Other Age-Related Neurodegenerative Diseases
    • Montaron MF, Drapeau E, Dupret D, Kitchener P, Aurousseau C, Le Moal M et al (2006). Lifelong corticosterone level DEtermines age-related DEcline in neurogenesis and memory. Neurobiol Aging 27: 645-654. (Pubitemid 43290533)
    • (2006) Neurobiology of Aging , vol.27 , Issue.4 , pp. 645-654
    • Montaron, M.F.1    Drapeau, E.2    Dupret, D.3    Kitchener, P.4    Aurousseau, C.5    Le Moal, M.6    Piazza, P.V.7    Abrous, D.N.8
  • 48
    • 0022263143 scopus 로고
    • Nerve membrane ionic channels as the primary target of pyrethroids
    • Narahashi T (1985). Nerve membrane ionic channels as the primary target of pyrethroids. Neurotoxicol 6: 3-22. (Pubitemid 15012349)
    • (1985) NeuroToxicology , vol.6 , Issue.2 , pp. 3-22
    • Narahashi, T.1
  • 50
    • 79151480276 scopus 로고    scopus 로고
    • Predictable chronic mild stress improves mood, hippocampal neurogenesis and memory
    • Parihar VK, Hattiangady B, Kuruba R, Shuai B, Shetty AK (2011). Predictable chronic mild stress improves mood, hippocampal neurogenesis and memory. Mol Psychiatry 16: 171-183.
    • (2011) Mol Psychiatry , vol.16 , pp. 171-183
    • Parihar, V.K.1    Hattiangady, B.2    Kuruba, R.3    Shuai, B.4    Shetty, A.K.5
  • 52
    • 79954494320 scopus 로고    scopus 로고
    • Necessity of hippocampal neurogenesis for the therapeutic action of antiDEpressants in adult nonhuman primates
    • Perera TD, Dwork AJ, Keegan KA, Thirumangalakudi L, Lipira CM, Joyce N et al (2011). Necessity of hippocampal neurogenesis for the therapeutic action of antiDEpressants in adult nonhuman primates. PLoS One 6: e17600.
    • (2011) PLoS One , vol.6
    • Perera, T.D.1    Dwork, A.J.2    Keegan, K.A.3    Thirumangalakudi, L.4    Lipira, C.M.5    Joyce, N.6
  • 53
    • 33747198141 scopus 로고    scopus 로고
    • A reassessment of the neurotoxicity of pyrethroid insecticides
    • DOI 10.1016/j.pharmthera.2005.10.003, PII S0163725805002160
    • Ray DE, Fry JR (2006). A reassessment of the neurotoxicity of pyrethroid insecticiDEs. Pharmacol Ther 111: 174-193. (Pubitemid 44226293)
    • (2006) Pharmacology and Therapeutics , vol.111 , Issue.1 , pp. 174-193
    • Ray, D.E.1    Fry, J.R.2
  • 55
    • 72949102234 scopus 로고    scopus 로고
    • Vulnerability of hippocampal GABA-ergic interneurons to kainate induced excitotoxic injury during old age
    • Shetty AK, Hattiangady B, Rao MS (2009). Vulnerability of hippocampal GABA-ergic interneurons to kainate induced excitotoxic injury during old age. J Cell Mol Med 13: 2408-2423.
    • (2009) J Cell Mol Med , vol.13 , pp. 2408-2423
    • Shetty, A.K.1    Hattiangady, B.2    Rao, M.S.3
  • 56
    • 8844264527 scopus 로고    scopus 로고
    • Hippocampal neurotrophin levels after injury: Relationship to the age of the hippocampus at the time of injury
    • DOI 10.1002/jnr.20302
    • Shetty AK, Rao MS, Hattiangady B, Zaman V, Shetty GA (2004). Hippocampal neurotrophin levels after injury: Relationship to the age of the hippocampus at the time of injury. J Neurosci Res 78: 520-532. (Pubitemid 39536496)
    • (2004) Journal of Neuroscience Research , vol.78 , Issue.4 , pp. 520-532
    • Shetty, A.K.1    Rao, M.S.2    Hattiangady, B.3    Zaman, V.4    Shetty, G.A.5
  • 58
    • 80052050190 scopus 로고    scopus 로고
    • Adult hippocampal neurogenesis buffers stress responses and DEpressive behavior
    • SnyDEr JS, Soumier AM, Brewer M, Pickel J, Cameron HA (2011). Adult hippocampal neurogenesis buffers stress responses and DEpressive behavior. Nature 476: 458-461.
    • (2011) Nature , vol.476 , pp. 458-461
    • Snyder, J.S.1    Soumier, A.M.2    Brewer, M.3    Pickel, J.4    Cameron, H.A.5
  • 59
    • 0034669707 scopus 로고    scopus 로고
    • Prevalence and patterns of Gulf war illness in Kansas veterans: Association of symptoms with characteristics of person, place, time of military service
    • Steele L (2000). Prevalence and patterns of Gulf war illness in Kansas veterans: association of symptoms with characteristics of person, place, time of military service. Am J EpiDEmiol 152: 992-1002.
    • (2000) Am J EpiDEmiol , vol.152 , pp. 992-1002
    • Steele, L.1
  • 60
    • 84855219138 scopus 로고    scopus 로고
    • Complex factors in the etiology of Gulf War illness: Wartime exposures and risk factors in veteran subgroups
    • Steele L, Sastre A, Gerkovich MM, Cook MR (2012). Complex factors in the etiology of Gulf War illness: wartime exposures and risk factors in veteran subgroups. Environ Health Perspect 120: 112-118.
    • (2012) Environ Health Perspect , vol.120 , pp. 112-118
    • Steele, L.1    Sastre, A.2    Gerkovich, M.M.3    Cook, M.R.4
  • 61
    • 80053572218 scopus 로고    scopus 로고
    • Organophosphates dysregulate dopamine signaling, glutamatergic neurotransmission, and induce neuronal injury markers in striatum
    • Torres-Altoro MI, Mathur BN, Drerup JM, Thomas R, Lovinger DM, O'Callaghan JP et al (2011). Organophosphates dysregulate dopamine signaling, glutamatergic neurotransmission, and induce neuronal injury markers in striatum. J Neurochem 119: 303-313.
    • (2011) J Neurochem , vol.119 , pp. 303-313
    • Torres-Altoro, M.I.1    Mathur, B.N.2    Drerup, J.M.3    Thomas, R.4    Lovinger, D.M.5    O'Callaghan, J.P.6
  • 62
    • 0024158498 scopus 로고    scopus 로고
    • Thigmotaxis as a test for anxiolytic activity in rats
    • Treit D, Fundytus M (1998). Thigmotaxis as a test for anxiolytic activity in rats. Pharmacol Biochem Behav 31: 959-962.
    • (1998) Pharmacol Biochem Behav , vol.31 , pp. 959-962
    • Treit, D.1    Fundytus, M.2
  • 63
    • 25444533023 scopus 로고    scopus 로고
    • Exercise enhances learning and hippocampal neurogenesis in aged mice
    • DOI 10.1523/JNEUROSCI.1731-05.2005
    • van Praag H, Shubert T, Zhao C, Gage FH (2005). Exercise enhances learning and hippocampal neurogenesis in aged mice. J Neurosci 25: 8680-8685. (Pubitemid 41362045)
    • (2005) Journal of Neuroscience , vol.25 , Issue.38 , pp. 8680-8685
    • Van Praag, H.1    Shubert, T.2    Zhao, C.3    Gage, F.H.4
  • 64
    • 0028224461 scopus 로고
    • Retrospective analysis of calls to Poison Control Centers resulting from exposure to the insect repellent N,N-diethyl-m-toluamide (DEET) from 1985-1989
    • Veltri JC, Osimitz TG, Bradford DC, Page BC (1994). Retrospective analysis of calls to poison control centers resulting from exposure to the insect repellent N,N-diethyl-m-toluamiDE (DEET) from 1985-1989. J Toxicol Clin Toxicol 32: 1-16. (Pubitemid 24089285)
    • (1994) Journal of Toxicology - Clinical Toxicology , vol.32 , Issue.1 , pp. 1-16
    • Veltri, J.C.1    Osimitz, T.G.2    Bradford, D.C.3    Page, B.C.4
  • 65
    • 0025610654 scopus 로고
    • Neurotoxicological effects and the moDE of action of pyrethroid insecticiDEs
    • Vijverberg HP, van DEn Bercken J (1990). Neurotoxicological effects and the moDE of action of pyrethroid insecticiDEs. Crit Rev Toxicol 21: 105-126.
    • (1990) Crit Rev Toxicol , vol.21 , pp. 105-126
    • Vijverberg, H.P.1    Van Den Bercken, J.2
  • 67
    • 84863614868 scopus 로고    scopus 로고
    • Metformin activates an atypical PKC-CBP pathway to promote neurogenesis and enhance spatial memory formation
    • Wang J, Gallagher D, DEVito LM, Cancino GI, Tsui D, He L et al (2012). Metformin activates an atypical PKC-CBP pathway to promote neurogenesis and enhance spatial memory formation. Cell Stem Cell 11: 23-35.
    • (2012) Cell Stem Cell , vol.11 , pp. 23-35
    • Wang, J.1    Gallagher, D.2    Devito, L.M.3    Cancino, G.I.4    Tsui, D.5    He, L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.