-
1
-
-
79959886270
-
Amyloid precursor protein processing and Alzheimer's disease
-
O'Brien RJ, Wong PC (2011) Amyloid precursor protein processing and Alzheimer's disease. Annu Rev Neurosci 34, 185-204.
-
(2011)
Annu Rev Neurosci
, vol.34
, pp. 185-204
-
-
O'Brien, R.J.1
Wong, P.C.2
-
2
-
-
84863245760
-
Defects in mitochondrial dynamics and metabolomic signatures of evolving energetic stress in mouse models of familial Alzheimer's disease
-
Trushina E, Nemutlu E, Zhang S, Christensen T, Camp J, Mesa J, Siddiqui A, Tamura Y, Sesaki H, Wengenack TM, Dzeja PP, Poduslo JF (2012) Defects in mitochondrial dynamics and metabolomic signatures of evolving energetic stress in mouse models of familial Alzheimer's disease. PLoS One 7, e32737.
-
(2012)
PLoS One
, vol.7
-
-
Trushina, E.1
Nemutlu, E.2
Zhang, S.3
Christensen, T.4
Camp, J.5
Mesa, J.6
Siddiqui, A.7
Tamura, Y.8
Sesaki, H.9
Wengenack, T.M.10
Dzeja, P.P.11
Poduslo, J.F.12
-
3
-
-
84877888815
-
Identification of altered metabolic pathways in plasma and CSF in mild cognitive impairment and Alzheimer's disease using metabolomics
-
Trushina E, Dutta T, Persson XM, Mielke MM, Petersen RC (2013) Identification of altered metabolic pathways in plasma and CSF in mild cognitive impairment and Alzheimer's disease using metabolomics. PLoS One 8, e63644.
-
(2013)
PLoS One
, vol.8
-
-
Trushina, E.1
Dutta, T.2
Persson, X.M.3
Mielke, M.M.4
Petersen, R.C.5
-
4
-
-
84857125516
-
The SAMP8 mouse: A model to develop therapeutic interventions for Alzheimer's disease
-
Morley JE, Farr SA, Kumar VB, Armbrecht HJ (2012) The SAMP8 mouse: A model to develop therapeutic interventions for Alzheimer's disease. Curr Pharm Des 18, 1123-1130.
-
(2012)
Curr Pharm des
, vol.18
, pp. 1123-1130
-
-
Morley, J.E.1
Farr, S.A.2
Kumar, V.B.3
Armbrecht, H.J.4
-
5
-
-
84858157217
-
The senescence accelerated mouse (SAMP8) as a model for oxida-tive stress and Alzheimer's disease
-
Morley JE, Armbrecht HJ, Farr SA, Kumar VB (2012) The senescence accelerated mouse (SAMP8) as a model for oxida-tive stress and Alzheimer's disease. Biochim Biophys Acta 1822, 650-656.
-
(2012)
Biochim Biophys Acta
, vol.1822
, pp. 650-656
-
-
Morley, J.E.1
Armbrecht, H.J.2
Farr, S.A.3
Kumar, V.B.4
-
6
-
-
25844496169
-
Lipid alterations in the earliest clinically recognizable stage of Alzheimer's disease: Implication of the role of lipids in the pathogenesis of Alzheimer's disease
-
Han X (2005) Lipid alterations in the earliest clinically recognizable stage of Alzheimer's disease: Implication of the role of lipids in the pathogenesis of Alzheimer's disease. Curr Alzheimer Res 2, 65-77.
-
(2005)
Curr Alzheimer Res
, vol.2
, pp. 65-77
-
-
Han, X.1
-
7
-
-
84866341940
-
Cholesterol and synaptic compensatory mechanisms in Alzheimer's disease mice brain during aging
-
Jansen D, Janssen CI, Vanmierlo T, Dederen PJ, van Rooij D, Zinnhardt B, Nobelen CL, Janssen AL, Hafkemeijer A, Mut-saers MP, Doedee AM, Kuipers AA, Broersen LM, Mulder M, Kiliaan AJ (2012) Cholesterol and synaptic compensatory mechanisms in Alzheimer's disease mice brain during aging. J Alzheimers Dis 31, 813-826.
-
(2012)
J Alzheimers Dis
, vol.31
, pp. 813-826
-
-
Jansen, D.1
Janssen, C.I.2
Vanmierlo, T.3
Dederen, P.J.4
Van Rooij, D.5
Zinnhardt, B.6
Nobelen, C.L.7
Janssen, A.L.8
Hafkemeijer, A.9
Mut-Saers, M.P.10
Doedee, A.M.11
Kuipers, A.A.12
Broersen, L.M.13
Mulder, M.14
Kiliaan, A.J.15
-
8
-
-
84872498729
-
Role of cholesterol in APP metabolism and its significance in Alzheimer's disease pathogenesis
-
Maulik M, Westaway D, Jhamandas JH, Kar S (2013) Role of cholesterol in APP metabolism and its significance in Alzheimer's disease pathogenesis. Mol Neurobiol 47, 37-63.
-
(2013)
Mol Neurobiol
, vol.47
, pp. 37-63
-
-
Maulik, M.1
Westaway, D.2
Jhamandas, J.H.3
Kar, S.4
-
9
-
-
18244390483
-
Mitochondrial abnormalities in Alzheimer brain: Mechanistic implications
-
Bubber P, Haroutunian V, Fisch G, Blass JP, Gibson GE (2005) Mitochondrial abnormalities in Alzheimer brain: Mechanistic implications. Ann Neurol 57, 695-703.
-
(2005)
Ann Neurol
, vol.57
, pp. 695-703
-
-
Bubber, P.1
Haroutunian, V.2
Fisch, G.3
Blass, J.P.4
Gibson, G.E.5
-
10
-
-
84864311250
-
Estrogen regulation of mito-chondrial bioenergetics: Implications for prevention of Alzheimer's disease
-
Yao J, Brinton RD (2012) Estrogen regulation of mito-chondrial bioenergetics: Implications for prevention of Alzheimer's disease. Adv Pharmacol 64, 327-371.
-
(2012)
Adv Pharmacol
, vol.64
, pp. 327-371
-
-
Yao, J.1
Brinton, R.D.2
-
11
-
-
0022966681
-
A postmortem study of amino acid neurotransmitters in Alzheimer's disease
-
Ellison DW, Beal MF, Mazurek MF, Bird ED, Martin JB (1986) A postmortem study of amino acid neurotransmitters in Alzheimer's disease. Ann Neurol 20, 616-621.
-
(1986)
Ann Neurol
, vol.20
, pp. 616-621
-
-
Ellison, D.W.1
Beal, M.F.2
Mazurek, M.F.3
Bird, E.D.4
Martin, J.B.5
-
12
-
-
84867579571
-
Altered neurochemical profile in the McGill-R-Thy1-APP rat model of Alzheimer's disease: A longitudinal in vivo 1 H MRS study
-
Nilsen LH, Melo TM, Saether O, Witter MP, Sonnewald U (2012) Altered neurochemical profile in the McGill-R-Thy1-APP rat model of Alzheimer's disease: A longitudinal in vivo 1 H MRS study. J Neurochem 123, 532-541.
-
(2012)
J Neurochem
, vol.123
, pp. 532-541
-
-
Nilsen, L.H.1
Melo, T.M.2
Saether, O.3
Witter, M.P.4
Sonnewald, U.5
-
14
-
-
0033102614
-
Age-related defects in lifespan and learning ability in SAMP8 mice
-
Nomura Y, Okuma Y (1999) Age-related defects in lifespan and learning ability in SAMP8 mice. Neurobiol Aging 20, 111-115.
-
(1999)
Neurobiol Aging
, vol.20
, pp. 111-115
-
-
Nomura, Y.1
Okuma, Y.2
-
15
-
-
79956324801
-
Age-related autophagy alterations in the brain of senescence accelerated mouse prone 8 (SAMP8) mice
-
Ma Q, Qiang J, Gu P, Wang Y, Geng Y, Wang M (2011) Age-related autophagy alterations in the brain of senescence accelerated mouse prone 8 (SAMP8) mice. Exp Gerontol 46, 533-541.
-
(2011)
Exp Gerontol
, vol.46
, pp. 533-541
-
-
Ma, Q.1
Qiang, J.2
Gu, P.3
Wang, Y.4
Geng, Y.5
Wang, M.6
-
16
-
-
54549091125
-
Systems biology: Metabo-nomics
-
Nicholson JK, Lindon JC (2008) Systems biology: Metabo-nomics. Nature 455, 1054-1056.
-
(2008)
Nature
, vol.455
, pp. 1054-1056
-
-
Nicholson, J.K.1
Lindon, J.C.2
-
17
-
-
80051704393
-
Quantitative metabolomics based on gas chromatography mass spectrometry: Status and perspectives
-
Koek MM, Jellema RH, van der Greef J, Tas AC, Han-kemeier T (2011) Quantitative metabolomics based on gas chromatography mass spectrometry: Status and perspectives. Metabolomics 7, 307-328.
-
(2011)
Metabolomics
, vol.7
, pp. 307-328
-
-
Koek, M.M.1
Jellema, R.H.2
Van Der Greef, J.3
Tas, A.C.4
Han-Kemeier, T.5
-
18
-
-
69749090221
-
Metabolomic study for diagnostic model of oesophageal cancer using gas chromatography/mass spec-trometry
-
Wu H, Xue R, Lu C, Deng C, Liu T, Zeng H, Wang Q, Shen X (2009) Metabolomic study for diagnostic model of oesophageal cancer using gas chromatography/mass spec-trometry. J Chromatogr B Analyt Technol Biomed Life Sci 877, 3111-3117.
-
(2009)
J Chromatogr B Analyt Technol Biomed Life Sci
, vol.877
, pp. 3111-3117
-
-
Wu, H.1
Xue, R.2
Lu, C.3
Deng, C.4
Liu, T.5
Zeng, H.6
Wang, Q.7
Shen, X.8
-
19
-
-
21044447078
-
Extraction, interpretation and validation of information for comparing samples in metabolic LC/MS data sets
-
Jonsson P, Bruce SJ, Moritz T, Trygg J, Sjostrom M, Plumb R, Granger J, Maibaum E, Nicholson JK, Holmes E, Antti H (2005) Extraction, interpretation and validation of information for comparing samples in metabolic LC/MS data sets. Analyst 130, 701-707.
-
(2005)
Analyst
, vol.130
, pp. 701-707
-
-
Jonsson, P.1
Bruce, S.J.2
Moritz, T.3
Trygg, J.4
Sjostrom, M.5
Plumb, R.6
Granger, J.7
Maibaum, E.8
Nicholson, J.K.9
Holmes, E.10
Antti, H.11
-
20
-
-
77949556929
-
Age-related changesinmetabolic profilesofrat hippocampus and cortices
-
Paban V, Fauvelle F, Alescio-Lautier B (2010) Age-related changesinmetabolic profilesofrat hippocampus and cortices. Eur J Neurosci 31, 1063-1073.
-
(2010)
Eur J Neurosci
, vol.31
, pp. 1063-1073
-
-
Paban, V.1
Fauvelle, F.2
Alescio-Lautier, B.3
-
21
-
-
64049103209
-
Metabonomic alterations in hippocampus, temporal and prefrontal cortex with age in rats
-
Zhang X, Liu H, Wu J, Liu M, Wang Y (2009) Metabonomic alterations in hippocampus, temporal and prefrontal cortex with age in rats. Neurochem Int 54, 481-487.
-
(2009)
Neurochem Int
, vol.54
, pp. 481-487
-
-
Zhang, X.1
Liu, H.2
Wu, J.3
Liu, M.4
Wang, Y.5
-
22
-
-
77953124257
-
A metabolomic study of the CRND8 transgenic mouse model of Alzheimer's disease
-
Salek RM, Xia J, Innes A, Sweatman BC, Adalbert R, Randle S, McGowan E, Emson PC, Griffin JL (2010) A metabolomic study of the CRND8 transgenic mouse model of Alzheimer's disease. Neurochem Int 56, 937-947.
-
(2010)
Neurochem Int
, vol.56
, pp. 937-947
-
-
Salek, R.M.1
Xia, J.2
Innes, A.3
Sweatman, B.C.4
Adalbert, R.5
Randle, S.6
McGowan, E.7
Emson, P.C.8
Griffin, J.L.9
-
24
-
-
84870199964
-
Cholesterol and Alzheimer's disease: A still poorly understood correlation
-
Ricciarelli R, Canepa E, Marengo B, Marinari UM, Poli G, Pronzato MA, Domenicotti C (2012) Cholesterol and Alzheimer's disease: A still poorly understood correlation. IUBMB Life 64, 931-935.
-
(2012)
IUBMB Life
, vol.64
, pp. 931-935
-
-
Ricciarelli, R.1
Canepa, E.2
Marengo, B.3
Marinari, U.M.4
Poli, G.5
Pronzato, M.A.6
Domenicotti, C.7
-
25
-
-
0037108819
-
Liver X receptors in the central nervous system: From lipid homeostasis to neuronal degeneration
-
Wang L, Schuster GU, Hultenby K, Zhang Q, Andersson S, Gustafsson JA (2002) Liver X receptors in the central nervous system: From lipid homeostasis to neuronal degeneration. Proc Natl Acad Sci USA 99, 13878-13883.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 13878-13883
-
-
Wang, L.1
Schuster, G.U.2
Hultenby, K.3
Zhang, Q.4
Andersson, S.5
Gustafsson, J.A.6
-
26
-
-
84870783499
-
Lipid metabolism and neuroinflam-mation in Alzheimer's disease: A role for liver X receptors
-
Kang J, Rivest S (2012) Lipid metabolism and neuroinflam-mation in Alzheimer's disease: A role for liver X receptors. Endocr Rev 33, 715-746.
-
(2012)
Endocr Rev
, vol.33
, pp. 715-746
-
-
Kang, J.1
Rivest, S.2
-
27
-
-
84867579493
-
Statins have therapeutic potential for the treatment of Alzheimer's disease, likely via protection of the neurovascular unit in the AD brain
-
Kurata T, Kawai H, Miyazaki K, Kozuki M, Morimoto N, Ohta Y, Ikeda Y, Abe K (2012) Statins have therapeutic potential for the treatment of Alzheimer's disease, likely via protection of the neurovascular unit in the AD brain. J Neurol Sci 322, 59-63.
-
(2012)
J Neurol Sci
, vol.322
, pp. 59-63
-
-
Kurata, T.1
Kawai, H.2
Miyazaki, K.3
Kozuki, M.4
Morimoto, N.5
Ohta, Y.6
Ikeda, Y.7
Abe, K.8
-
28
-
-
80155191187
-
Statins: The role in the treatment and prevention of Alzheimer's neu-rodegeneration
-
Pac-Soo C, Lloyd DG, Vizcaychipi MP, Ma D (2011) Statins: The role in the treatment and prevention of Alzheimer's neu-rodegeneration. J Alzheimers Dis 27, 1-10.
-
(2011)
J Alzheimers Dis
, vol.27
, pp. 1-10
-
-
Pac-Soo, C.1
Lloyd, D.G.2
Vizcaychipi, M.P.3
Ma, D.4
-
29
-
-
79959858679
-
Glycerophospholipids and glycerophospholipid-derived lipid mediators: A complex meshwork in Alzheimer's disease pathology
-
Frisardi V, Panza F, Seripa D, Farooqui T, Farooqui AA (2011) Glycerophospholipids and glycerophospholipid-derived lipid mediators: A complex meshwork in Alzheimer's disease pathology. Prog Lipid Res 50, 313-330.
-
(2011)
Prog Lipid Res
, vol.50
, pp. 313-330
-
-
Frisardi, V.1
Panza, F.2
Seripa, D.3
Farooqui, T.4
Farooqui, A.A.5
-
30
-
-
76849108962
-
Fatty acid composition of frontal, temporal and parietal neocortex in the normal human brain and in Alzheimer's disease
-
Fraser T, Tayler H, Love S (2010) Fatty acid composition of frontal, temporal and parietal neocortex in the normal human brain and in Alzheimer's disease. Neurochem Res 35, 503-513.
-
(2010)
Neurochem Res
, vol.35
, pp. 503-513
-
-
Fraser, T.1
Tayler, H.2
Love, S.3
-
31
-
-
79954613332
-
Oleic acid ameliorates amyloidosis in cellular and mouse models of Alzheimer's disease
-
Amtul Z, Westaway D, Cechetto DF, Rozmahel RF (2011) Oleic acid ameliorates amyloidosis in cellular and mouse models of Alzheimer's disease. Brain Pathol 21, 321-329.
-
(2011)
Brain Pathol
, vol.21
, pp. 321-329
-
-
Amtul, Z.1
Westaway, D.2
Cechetto, D.F.3
Rozmahel, R.F.4
-
32
-
-
0026891186
-
Amino acid metabolism in neurodegen-erative diseases
-
Nakamura S (1992) [Amino acid metabolism in neurodegen-erative diseases]. Nihon Rinsho 50, 1637-1642.
-
(1992)
Nihon Rinsho
, vol.50
, pp. 1637-1642
-
-
Nakamura, S.1
-
33
-
-
84867898641
-
Structural analysis of the pyroglutamate-modified iso-form of the Alzheimer's disease-related amyloid-beta using NMR spectroscopy
-
Sun N, Hartmann R, Lecher J, Stoldt M, Funke SA, Gremer L, Ludwig HH, Demuth HU, Kleinschmidt M, Willbold D (2012) Structural analysis of the pyroglutamate-modified iso-form of the Alzheimer's disease-related amyloid-beta using NMR spectroscopy. J Pept Sci 18, 691-695.
-
(2012)
J Pept Sci
, vol.18
, pp. 691-695
-
-
Sun, N.1
Hartmann, R.2
Lecher, J.3
Stoldt, M.4
Funke, S.A.5
Gremer, L.6
Ludwig, H.H.7
Demuth, H.U.8
Kleinschmidt, M.9
Willbold, D.10
-
34
-
-
84885424849
-
Alzheimer's disease: Amino acid levels and brain metabolic status
-
Gueli MC, Taibi G (2013) Alzheimer's disease: Amino acid levels and brain metabolic status. Neurol Sci 34, 1575-1579.
-
(2013)
Neurol Sci
, vol.34
, pp. 1575-1579
-
-
Gueli, M.C.1
Taibi, G.2
-
35
-
-
84903154904
-
Recent advances in the application of metabolomics to Alzheimer's disease
-
doi: 10.1016/j.bbadis.2013.06.014
-
Trushina E, Mielke MM (2013) Recent advances in the application of metabolomics to Alzheimer's disease. Biochim Biophys Acta, doi: 10.1016/j.bbadis.2013.06.014
-
(2013)
Biochim Biophys Acta
-
-
Trushina, E.1
Mielke, M.M.2
-
36
-
-
23844505632
-
Monitoring disease progression in transgenic mouse models of Alzheimer's disease with proton magnetic resonance spectroscopy
-
Marjanska M, Curran GL, Wengenack TM, Henry PG, Bliss RL, Poduslo JF, Jack CR, Jr., Ugurbil K, Garwood M (2005) Monitoring disease progression in transgenic mouse models of Alzheimer's disease with proton magnetic resonance spectroscopy. Proc Natl Acad Sci USA 102, 11906-11910.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 11906-11910
-
-
Marjanska, M.1
Curran, G.L.2
Wengenack, T.M.3
Henry, P.G.4
Bliss, R.L.5
Poduslo, J.F.6
Jack Jr., C.R.7
Ugurbil, K.8
Garwood, M.9
-
37
-
-
47049101371
-
Age related changes in brain metabolites observed by 1H MRS in APP/PS1 mice
-
Oberg J, Spenger C, Wang FH, Andersson A, Westman E, Skoglund P, Sunnemark D, Norinder U, Klason T, Wahlund LO, Lindberg M (2008) Age related changes in brain metabolites observed by 1H MRS in APP/PS1 mice. Neurobiol Aging 29, 1423-1433.
-
(2008)
Neurobiol Aging
, vol.29
, pp. 1423-1433
-
-
Oberg, J.1
Spenger, C.2
Wang, F.H.3
Andersson, A.4
Westman, E.5
Skoglund, P.6
Sunnemark, D.7
Norinder, U.8
Klason, T.9
Wahlund, L.O.10
Lindberg, M.11
-
38
-
-
83755180492
-
Metabolome in progression to Alzheimer's disease
-
Oresic M, Hyotylainen T, Herukka SK, Sysi-Aho M, Mat-tila I, Seppanan-Laakso T, Julkunen V, Gopalacharyulu PV, Hallikainen M, Koikkalainen J, Kivipelto M, Helisalmi S, Lotjonen J, Soininen H (2011) Metabolome in progression to Alzheimer's disease. Transl Psychiatry 1, e57.
-
(2011)
Transl Psychiatry
, vol.1
-
-
Oresic, M.1
Hyotylainen, T.2
Herukka, S.K.3
Sysi-Aho, M.4
Mat-Tila, I.5
Seppanan-Laakso, T.6
Julkunen, V.7
Gopalacharyulu, P.V.8
Hallikainen, M.9
Koikkalainen, J.10
Kivipelto, M.11
Helisalmi, S.12
Lotjonen, J.13
Soininen, H.14
|