-
1
-
-
0019850002
-
A new murine model accelerated senescence
-
10.1016/0047-6374(81)90084-1
-
T Takeda M Hosokawa S Takeshita 1981 A new murine model accelerated senescence Mech Ageing Dev 17 183 194 10.1016/0047-6374(81)90084-1
-
(1981)
Mech Ageing Dev
, vol.17
, pp. 183-194
-
-
Takeda, T.1
Hosokawa, M.2
Takeshita, S.3
-
2
-
-
0021275014
-
Grading score system: A method for evaluation of the degree of senescence in senescence accelerated mouse (SAM)
-
10.1016/0047-6374(84)90168-4
-
M Hosokawa R Kasai K Higuchi 1994 Grading score system: a method for evaluation of the degree of senescence in senescence accelerated mouse (SAM) Mech Ageing Dev 26 91 102 10.1016/0047-6374(84)90168-4
-
(1994)
Mech Ageing Dev
, vol.26
, pp. 91-102
-
-
Hosokawa, M.1
Kasai, R.2
Higuchi, K.3
-
3
-
-
0025938219
-
Senescence-accelerated mouse (SAM): A novel murine model of accelerated senescence
-
T Takeda M Hosokawa K Higuchi 1991 Senescence-accelerated mouse (SAM): a novel murine model of accelerated senescence J Am Geriatr Soc 39 911 919
-
(1991)
J Am Geriatr Soc
, vol.39
, pp. 911-919
-
-
Takeda, T.1
Hosokawa, M.2
Higuchi, K.3
-
5
-
-
0030899547
-
Pathobiology of the senescence-accelerated mouse (SAM)
-
10.1016/S0531-5565(96)00068-X
-
T Takeda T Matsushita M Kurozumi 1997 Pathobiology of the senescence-accelerated mouse (SAM) Exp Gerontol 32 117 127 10.1016/S0531- 5565(96)00068-X
-
(1997)
Exp Gerontol
, vol.32
, pp. 117-127
-
-
Takeda, T.1
Matsushita, T.2
Kurozumi, M.3
-
6
-
-
0032847560
-
Senescence-accelerated mouse (SAM): A biogerontological resource in aging research
-
10.1016/S0197-4580(99)00008-1
-
T Takeda 1999 Senescence-accelerated mouse (SAM): a biogerontological resource in aging research Neurobiol Aging 20 105 110 10.1016/S0197-4580(99) 00008-1
-
(1999)
Neurobiol Aging
, vol.20
, pp. 105-110
-
-
Takeda, T.1
-
8
-
-
0028072343
-
Molecular genetic characterization of the senescence-accelerated mouse (SAM) strains
-
H Kitado K Higuchi T Takeda 1994 Molecular genetic characterization of the senescence-accelerated mouse (SAM) strains J Gerontol 49 B247 B254
-
(1994)
J Gerontol
, vol.49
-
-
Kitado, H.1
Higuchi, K.2
Takeda, T.3
-
9
-
-
84917731202
-
Genetic monitering system for SAM strains utilizing DNA markers
-
10.1016/S0531-5131(03)01579-6
-
M Mori K Higuchi 2004 Genetic monitering system for SAM strains utilizing DNA markers Int Congr Ser 1260 187 190 10.1016/S0531-5131(03)01579-6
-
(2004)
Int Congr ser
, vol.1260
, pp. 187-190
-
-
Mori, M.1
Higuchi, K.2
-
10
-
-
0022970786
-
Age-related changes in learning and memory in the senescence-accelerated mouse (SAM)
-
10.1016/0031-9384(86)90112-5
-
M Miyamoto Y Kiyota N Yamazaki 1986 Age-related changes in learning and memory in the senescence-accelerated mouse (SAM) Physiol Behav 38 399 406 10.1016/0031-9384(86)90112-5
-
(1986)
Physiol Behav
, vol.38
, pp. 399-406
-
-
Miyamoto, M.1
Kiyota, Y.2
Yamazaki, N.3
-
11
-
-
0024211998
-
Age-related deterioration of ability of acquisition in memory and learning in senescence-accelerated mouse; SAM-P/8 as an animal model of disturbances in recent memory
-
10.1016/0006-8993(88)90671-3
-
H Yagi S Katoh I Akiguchi 1988 Age-related deterioration of ability of acquisition in memory and learning in senescence-accelerated mouse; SAM-P/8 as an animal model of disturbances in recent memory Brain Res 474 86 93 10.1016/0006-8993(88)90671-3
-
(1988)
Brain Res
, vol.474
, pp. 86-93
-
-
Yagi, H.1
Katoh, S.2
Akiguchi, I.3
-
12
-
-
0026692163
-
Senescence-accelerated mouse (SAM): Age-related reduced anxiety-like behavior in the SAM-P/8 strain
-
10.1016/0031-9384(92)90081-C
-
M Miyamoto Y Kiyota M Nishiyama 1992 Senescence-accelerated mouse (SAM): age-related reduced anxiety-like behavior in the SAM-P/8 strain Physiol Behav 51 979 985 10.1016/0031-9384(92)90081-C
-
(1992)
Physiol Behav
, vol.51
, pp. 979-985
-
-
Miyamoto, M.1
Kiyota, Y.2
Nishiyama, M.3
-
13
-
-
0027476481
-
Age-related changes in foot shock avoidance acquisition and retention in senescence accelerated mouse (SAM)
-
10.1016/0197-4580(93)90091-O
-
JF Flood JE Morley 1993 Age-related changes in foot shock avoidance acquisition and retention in senescence accelerated mouse (SAM) Neurobiol Aging 14 153 157 10.1016/0197-4580(93)90091-O
-
(1993)
Neurobiol Aging
, vol.14
, pp. 153-157
-
-
Flood, J.F.1
Morley, J.E.2
-
14
-
-
0024434242
-
Behavioral characteristics of the SAM-P/8 strain in Sidman active avoidance task
-
10.1016/0006-8993(89)90421-6
-
A Ohta Y Hirano H Yagi 1989 Behavioral characteristics of the SAM-P/8 strain in Sidman active avoidance task Brain Res 498 195 198 10.1016/0006-8993(89)90421-6
-
(1989)
Brain Res
, vol.498
, pp. 195-198
-
-
Ohta, A.1
Hirano, Y.2
Yagi, H.3
-
15
-
-
0030896788
-
Characteristics of age-related behavioral changes in senescence- accelerated mouse SAMP8 and SAMP10
-
10.1016/S0531-5565(96)00061-7
-
M Miyamoto 1997 Characteristics of age-related behavioral changes in senescence-accelerated mouse SAMP8 and SAMP10 Exp Gerontol 32 139 148 10.1016/S0531-5565(96)00061-7
-
(1997)
Exp Gerontol
, vol.32
, pp. 139-148
-
-
Miyamoto, M.1
-
17
-
-
0031858787
-
Behavioral assessment senescence-accelerated mouse (SAMP8 and R1)
-
10.1016/S0031-9384(98)00011-0
-
A Markowska EL Spangler DK Ingram 1998 Behavioral assessment senescence-accelerated mouse (SAMP8 and R1) Physiol Behav 64 15 26 10.1016/S0031-9384(98)00011-0
-
(1998)
Physiol Behav
, vol.64
, pp. 15-26
-
-
Markowska, A.1
Spangler, E.L.2
Ingram, D.K.3
-
18
-
-
0026480277
-
Age-related changes in radial-arm maze learning and basal forebrain cholinergic systems in senescence accelerated mice (SAM)
-
10.1016/S0166-4328(05)80307-9
-
S Ikegami S Shumiya H Kawamura 1992 Age-related changes in radial-arm maze learning and basal forebrain cholinergic systems in senescence accelerated mice (SAM) Behav Brain Res 51 15 22 10.1016/S0166-4328(05)80307-9
-
(1992)
Behav Brain Res
, vol.51
, pp. 15-22
-
-
Ikegami, S.1
Shumiya, S.2
Kawamura, H.3
-
19
-
-
0026575905
-
Early onset of age-related impairment of aversive and appetitive learning in the SAM-P/8 mouse
-
JF Flood JE Morley 1992 Early onset of age-related impairment of aversive and appetitive learning in the SAM-P/8 mouse J Gerontol Biol Sci 47 B52 B59
-
(1992)
J Gerontol Biol Sci
, vol.47
-
-
Flood, J.F.1
Morley, J.E.2
-
20
-
-
0015004136
-
A simple and reliable conflict procedure for testing antianxiety agenta
-
10.1007/BF00403989
-
JR Vogel B Beer DE Clody 1971 A simple and reliable conflict procedure for testing antianxiety agenta Psychopharmacology (Berl) 21 1 7 10.1007/BF00403989
-
(1971)
Psychopharmacology (Berl)
, vol.21
, pp. 1-7
-
-
Vogel, J.R.1
Beer, B.2
Clody, D.E.3
-
21
-
-
0022385403
-
Attenuating effect of diazepam on stress-induced increases in noradrenalin turnover in specific brain regions of rats. Antagonism by Ro 15-1788
-
10.1016/0024-3205(85)90606-X
-
Y Ida M Tanaka A Tsuda 1985 Attenuating effect of diazepam on stress-induced increases in noradrenalin turnover in specific brain regions of rats. Antagonism by Ro 15-1788 Life Sci 37 2491 2498 10.1016/0024-3205(85)90606- X
-
(1985)
Life Sci
, vol.37
, pp. 2491-2498
-
-
Ida, Y.1
Tanaka, M.2
Tsuda, A.3
-
22
-
-
0024330780
-
3H]nitrendipine to cerebral cortical and hippocampal membranes of senescence-accelerated mouse
-
10.1016/0304-3940(89)90186-9
-
3H]nitrendipine to cerebral cortical and hippocampal membranes of senescence-accelerated mouse Neurosci Lett 196 334 338 10.1016/0304-3940(89)90186-9
-
(1989)
Neurosci Lett
, vol.196
, pp. 334-338
-
-
Kitamura, Y.1
Zhao, X.H.2
Ohnuki, T.3
-
23
-
-
0024997585
-
3H] noradrenaline in brain slices of senescence-accelerated mouse
-
10.1016/0736-5748(90)90032-W
-
3H]noradrenaline in brain slices of senescence-accelerated mouse Int J Dev Neurosci 8 267 272 10.1016/0736-5748(90)90032-W
-
(1990)
Int J Dev Neurosci
, vol.8
, pp. 267-272
-
-
Zhao, X.H.1
Nomura, Y.2
-
25
-
-
1842400980
-
Morphological changes of the strain of senescence accelerated mouse (SAM-P/8)
-
Takeda T, Matsuo T, Akiguchi I, Hosokawa M (eds) Fuji Printing Business Company, Kyoto
-
Akiguchi A, Akiyama H, Sugiyama H, et al. (1988) Morphological changes of the strain of senescence accelerated mouse (SAM-P/8). In: Takeda T, Matsuo T, Akiguchi I, Hosokawa M (eds) Proceedings of the first SAM Kyoto symposium. Fuji Printing Business Company, Kyoto, pp 67-76
-
(1988)
Proceedings of the First SAM Kyoto Symposium
, pp. 67-76
-
-
Akiguchi, A.1
Akiyama, H.2
Sugiyama, H.3
-
26
-
-
0023375690
-
Loss of dendritic spines in hippocampal CA1 pyramidal cells of senescence accelerated mouse (SAM). A quantitative Golgi study
-
H Sugiyama H Akiyama I Akiguchi 1987 Loss of dendritic spines in hippocampal CA1 pyramidal cells of senescence accelerated mouse (SAM). A quantitative Golgi study Clin Neurol 27 841 845
-
(1987)
Clin Neurol
, vol.27
, pp. 841-845
-
-
Sugiyama, H.1
Akiyama, H.2
Akiguchi, I.3
-
28
-
-
0027732004
-
β/A4 protein-like granular structures in the brain of senescence-accelerated mouse
-
M Takemura S Nakamura I Akiguchi 1993 β/A4 protein-like granular structures in the brain of senescence-accelerated mouse Am J Pathol 142 1887 1897
-
(1993)
Am J Pathol
, vol.142
, pp. 1887-1897
-
-
Takemura, M.1
Nakamura, S.2
Akiguchi, I.3
-
29
-
-
0028167990
-
Colocalization of prolyl endopeptidase and amyloid β-peptide in brains of senescence-accelerated mouse
-
10.1016/0304-3940(94)90082-5
-
A Fukunari A Kato Y Sasaki 1994 Colocalization of prolyl endopeptidase and amyloid β-peptide in brains of senescence-accelerated mouse Neurosci Lett 176 201 204 10.1016/0304-3940(94)90082-5
-
(1994)
Neurosci Lett
, vol.176
, pp. 201-204
-
-
Fukunari, A.1
Kato, A.2
Sasaki, Y.3
-
30
-
-
0034867485
-
Site-directed antisense oligonucleotide decreases the expression of amyloid precursor protein and reverses deficits in learning and memory in aged SAMP8 mice
-
10.1016/S0196-9781(00)00339-9
-
VB Kumar SA Farr JF Flood 2000 Site-directed antisense oligonucleotide decreases the expression of amyloid precursor protein and reverses deficits in learning and memory in aged SAMP8 mice Peptides 21 1769 1775 10.1016/S0196-9781(00)00339-9
-
(2000)
Peptides
, vol.21
, pp. 1769-1775
-
-
Kumar, V.B.1
Farr, S.A.2
Flood, J.F.3
-
31
-
-
0034531444
-
β-amyloid precursor polypeptide in SAMP8 mice affects learning and memory
-
10.1016/S0196-9781(00)00342-9
-
JE Morley VB Kumar AE Bernardo 2000 β-amyloid precursor polypeptide in SAMP8 mice affects learning and memory Peptides 21 1761 1767 10.1016/S0196-9781(00)00342-9
-
(2000)
Peptides
, vol.21
, pp. 1761-1767
-
-
Morley, J.E.1
Kumar, V.B.2
Bernardo, A.E.3
-
33
-
-
0022869476
-
Periodic acid-Schiff (PAS)-positive granular structures in the brain of senescence accelerated mouse (SAM)
-
10.1007/BF00685973
-
H Akiyama M Kameyama I Akiguchi 1986 Periodic acid-Schiff (PAS)-positive granular structures in the brain of senescence accelerated mouse (SAM) Acta Neuropathol 72 124 129 10.1007/BF00685973
-
(1986)
Acta Neuropathol
, vol.72
, pp. 124-129
-
-
Akiyama, H.1
Kameyama, M.2
Akiguchi, I.3
-
34
-
-
0028363925
-
Age-related deposition of glia-associated fibrillar material in brains of C57BL/6 mice
-
10.1016/0306-4522(94)90269-0
-
M Jucker LC Walker P Schwarb 1994 Age-related deposition of glia-associated fibrillar material in brains of C57BL/6 mice Neuroscience 60 875 889 10.1016/0306-4522(94)90269-0
-
(1994)
Neuroscience
, vol.60
, pp. 875-889
-
-
Jucker, M.1
Walker, L.C.2
Schwarb, P.3
-
35
-
-
0030564955
-
Similarities in the age-related hippocampal deposition of periodic acid-Schiff-positive granules in the senescence-accelerated mouse P8 and C57BL/6 mouse strains
-
10.1016/0306-4522(96)00169-8
-
H Kuo DK Ingram LC Walker 1996 Similarities in the age-related hippocampal deposition of periodic acid-Schiff-positive granules in the senescence-accelerated mouse P8 and C57BL/6 mouse strains Neuroscience 74 733 740 10.1016/0306-4522(96)00169-8
-
(1996)
Neuroscience
, vol.74
, pp. 733-740
-
-
Kuo, H.1
Ingram, D.K.2
Walker, L.C.3
-
36
-
-
85044550156
-
Spontaneous spongy degeneration of the brain stem in SAM-P/8 mice, a newly developed memory deficient strain
-
10.1097/00005072-198909000-00008
-
H Yagi M Irino T Matsushita 1989 Spontaneous spongy degeneration of the brain stem in SAM-P/8 mice, a newly developed memory deficient strain J Neuropathol Exp Neurol 48 577 590 10.1097/00005072-198909000-00008
-
(1989)
J Neuropathol Exp Neurol
, vol.48
, pp. 577-590
-
-
Yagi, H.1
Irino, M.2
Matsushita, T.3
-
37
-
-
0032571747
-
Spontaneous and artificial lesions of magnocellular reticular formation of brainstem deteriorate avoidance learning in senescence-accelerated mouse SAM
-
10.1016/S0006-8993(98)00070-5
-
H Yagi I Akiguchi A Ohta 1998 Spontaneous and artificial lesions of magnocellular reticular formation of brainstem deteriorate avoidance learning in senescence-accelerated mouse SAM Brain Res 791 90 98 10.1016/S0006-8993(98) 00070-5
-
(1998)
Brain Res
, vol.791
, pp. 90-98
-
-
Yagi, H.1
Akiguchi, I.2
Ohta, A.3
-
38
-
-
0022596314
-
Brain stem reticular formation neural correlates of stimulus significance and behavior during discriminative avoidance conditioning in rabbits
-
10.1037/0735-7044.100.2.171
-
M Gabriel B Gregg A Clancy 1986 Brain stem reticular formation neural correlates of stimulus significance and behavior during discriminative avoidance conditioning in rabbits Behav Neurosci 100 171 184 10.1037/0735-7044.100.2.171
-
(1986)
Behav Neurosci
, vol.100
, pp. 171-184
-
-
Gabriel, M.1
Gregg, B.2
Clancy, A.3
-
39
-
-
0342525333
-
Reactive microglia in the brain of senescence-accelerated mouse (SAM): An histochemical study
-
T Kitabayashi H Tomimoto H Akiyama 1993 Reactive microglia in the brain of senescence-accelerated mouse (SAM): an histochemical study Can J Neurol Sci 20 146
-
(1993)
Can J Neurol Sci
, vol.20
, pp. 146
-
-
Kitabayashi, T.1
Tomimoto, H.2
Akiyama, H.3
-
40
-
-
0028879125
-
Increased expression of cathepsine e and D in reactive microglial cells associated with spongiform degeneration in the brain stem of senescence-accelerated mouse
-
10.1006/exnr.1995.1094
-
T Amano H Nakanishi M Oka 1995 Increased expression of cathepsine E and D in reactive microglial cells associated with spongiform degeneration in the brain stem of senescence-accelerated mouse Exp Neurol 136 171 182 10.1006/exnr.1995.1094
-
(1995)
Exp Neurol
, vol.136
, pp. 171-182
-
-
Amano, T.1
Nakanishi, H.2
Oka, M.3
-
41
-
-
0036841239
-
Analysis of the expression of endogenous murine leukemia viruses in the brains of senescence-accelerated mice (SAMP8) and the relationship between expression and brain histopathology
-
BH Jeong JK Jin EK Choi 2002 Analysis of the expression of endogenous murine leukemia viruses in the brains of senescence-accelerated mice (SAMP8) and the relationship between expression and brain histopathology J Neuropathol Exp Neurol 61 1001 1012
-
(2002)
J Neuropathol Exp Neurol
, vol.61
, pp. 1001-1012
-
-
Jeong, B.H.1
Jin, J.K.2
Choi, E.K.3
-
42
-
-
0030700686
-
Titers of murine leukemia virus are higher in brains of SAMP8 than SAMR1 mice
-
10.1016/S0197-4580(97)00041-9
-
HC Meeker RL Carp 1997 Titers of murine leukemia virus are higher in brains of SAMP8 than SAMR1 mice Neurobiol Aging 18 543 547 10.1016/S0197- 4580(97)00041-9
-
(1997)
Neurobiol Aging
, vol.18
, pp. 543-547
-
-
Meeker, H.C.1
Carp, R.L.2
-
43
-
-
0037204534
-
Murine leukemia virus in organs of senescence-prone and-resistant mouse strains
-
10.1016/S0047-6374(01)00377-3
-
RL Carp HC Meeker R Chung 2002 Murine leukemia virus in organs of senescence-prone and-resistant mouse strains Mech Ageing Dev 123 575 584 10.1016/S0047-6374(01)00377-3
-
(2002)
Mech Ageing Dev
, vol.123
, pp. 575-584
-
-
Carp, R.L.1
Meeker, H.C.2
Chung, R.3
-
44
-
-
0029036488
-
Regional differences in the age-related reduction of the cerebellar cortical thickness in senescence-accelerated mice
-
S Nagasaki S Ozono K Kawamura 1995 Regional differences in the age-related reduction of the cerebellar cortical thickness in senescence-accelerated mice Med Sci Res 23 425 427
-
(1995)
Med Sci Res
, vol.23
, pp. 425-427
-
-
Nagasaki, S.1
Ozono, S.2
Kawamura, K.3
-
45
-
-
34548445576
-
Cell death in the Purkinje cells of the cerebellum of senescence accelerated mouse (SAMP8)
-
10.1007/s10522-007-9097-3
-
Y Zhu CC Lee WC Lam 2007 Cell death in the Purkinje cells of the cerebellum of senescence accelerated mouse (SAMP8) Biogerontology 8 537 544 10.1007/s10522-007-9097-3
-
(2007)
Biogerontology
, vol.8
, pp. 537-544
-
-
Zhu, Y.1
Lee, C.C.2
Lam, W.C.3
-
46
-
-
0030590225
-
Purkinje cell loss and astrocytosis in the cerebellum in familial and sporadic Alzheimer's disease
-
10.1016/0304-3940(96)12875-5
-
Y Fukutani NJ Cairns MN Rossor 1996 Purkinje cell loss and astrocytosis in the cerebellum in familial and sporadic Alzheimer's disease Neurosci Lett 214 33 36 10.1016/0304-3940(96)12875-5
-
(1996)
Neurosci Lett
, vol.214
, pp. 33-36
-
-
Fukutani, Y.1
Cairns, N.J.2
Rossor, M.N.3
-
47
-
-
0035106551
-
Alzheimer's disease and the cerebellum: A morphologic study on neuronal and glial changes
-
10.1159/000051260
-
M Sjobeck E Englund 2001 Alzheimer's disease and the cerebellum: a morphologic study on neuronal and glial changes Dement Geriatr Cogn Disord 12 211 218 10.1159/000051260
-
(2001)
Dement Geriatr Cogn Disord
, vol.12
, pp. 211-218
-
-
Sjobeck, M.1
Englund, E.2
-
48
-
-
0031449895
-
Immunocytochemical study of catecholaminergic neurons in the senescence-accelerated mouse (SAM-P8) brain
-
10.1007/BF01294727
-
N Karasawa I Nagatsu K Sakai 1997 Immunocytochemical study of catecholaminergic neurons in the senescence-accelerated mouse (SAM-P8) brain J Neural Transm 104 1267 1275 10.1007/BF01294727
-
(1997)
J Neural Transm
, vol.104
, pp. 1267-1275
-
-
Karasawa, N.1
Nagatsu, I.2
Sakai, K.3
-
49
-
-
21144455520
-
The age-related degeneration of oligodendrocytes in the hippocampus of the senescence-accelerated mouse (SAM) P8: A quantitative immunohistochemical study
-
10.1248/bpb.28.615
-
J Tanaka Y Okuma K Tomobe 2005 The age-related degeneration of oligodendrocytes in the hippocampus of the senescence-accelerated mouse (SAM) P8: a quantitative immunohistochemical study Biol Pharm Bull 28 615 618 10.1248/bpb.28.615
-
(2005)
Biol Pharm Bull
, vol.28
, pp. 615-618
-
-
Tanaka, J.1
Okuma, Y.2
Tomobe, K.3
-
50
-
-
0027129137
-
Age-related changes in transmitter glutamate and NMDA receptor/channels in the brain of senescence-accelerated mouse
-
10.1016/0304-3940(92)90396-O
-
Y Kitamura XH Zhao T Ohnuki 1992 Age-related changes in transmitter glutamate and NMDA receptor/channels in the brain of senescence-accelerated mouse Neurosci Lett 137 169 172 10.1016/0304-3940(92)90396-O
-
(1992)
Neurosci Lett
, vol.137
, pp. 169-172
-
-
Kitamura, Y.1
Zhao, X.H.2
Ohnuki, T.3
-
51
-
-
0031080875
-
Alterations in acetylcholine, NMDA, benzodiazepine receptors and protein kinase C in the brain of the senescence-accelerated mouse: An animal model useful for studies on cognitive enhancers
-
10.1016/S0166-4328(97)86045-7
-
Y Nomura Y Kitamura T Ohnuki 1997 Alterations in acetylcholine, NMDA, benzodiazepine receptors and protein kinase C in the brain of the senescence-accelerated mouse: an animal model useful for studies on cognitive enhancers Behav Brain Res 83 51 55 10.1016/S0166-4328(97)86045-7
-
(1997)
Behav Brain Res
, vol.83
, pp. 51-55
-
-
Nomura, Y.1
Kitamura, Y.2
Ohnuki, T.3
-
52
-
-
0026519991
-
3H]acetylcholine release from brain slices of senescence-accelerated mouse
-
10.1016/0736-5748(92)90040-7
-
3H]acetylcholine release from brain slices of senescence-accelerated mouse Int J Dev Neurosci 10 121 129 10.1016/0736-5748(92)90040-7
-
(1992)
Int J Dev Neurosci
, vol.10
, pp. 121-129
-
-
Zhao, X.H.1
Kitamura, Y.2
Nomura, Y.3
-
53
-
-
0033102614
-
Age-related deficits in lifespan and learning ability in SAMP8 mice
-
10.1016/S0197-4580(99)00006-8
-
Y Nomura Y Okuma 1999 Age-related deficits in lifespan and learning ability in SAMP8 mice Neurobiol Aging 20 111 115 10.1016/S0197-4580(99)00006-8
-
(1999)
Neurobiol Aging
, vol.20
, pp. 111-115
-
-
Nomura, Y.1
Okuma, Y.2
-
54
-
-
0032826833
-
Effect of age on calcium-dependent proteins in hippocampus of senescence-accelerated mice
-
10.1016/S0006-8993(99)01802-8
-
HJ Armbrecht MA Boltz VB Kumar 1999 Effect of age on calcium-dependent proteins in hippocampus of senescence-accelerated mice Brain Res 842 287 293 10.1016/S0006-8993(99)01802-8
-
(1999)
Brain Res
, vol.842
, pp. 287-293
-
-
Armbrecht, H.J.1
Boltz, M.A.2
Kumar, V.B.3
-
55
-
-
0344653645
-
Learning and memory in the SAMP8 mouse
-
1. 10.1016/S0149-7634(96)00063-2
-
JF Flood JE Morley 1998 Learning and memory in the SAMP8 mouse Neurosci Biobehav Rev 22 1 1 20 10.1016/S0149-7634(96)00063-2
-
(1998)
Neurosci Biobehav Rev
, vol.22
, pp. 1-20
-
-
Flood, J.F.1
Morley, J.E.2
-
56
-
-
0037436472
-
Cholinergic deficits in the septal-hippocampal pathway of the SAM-P/8 senescence accelerated mouse
-
10.1016/S0006-8993(02)04192-6
-
R Strong V Reddy JE Morley 2003 Cholinergic deficits in the septal-hippocampal pathway of the SAM-P/8 senescence accelerated mouse Brain Res 966 150 156 10.1016/S0006-8993(02)04192-6
-
(2003)
Brain Res
, vol.966
, pp. 150-156
-
-
Strong, R.1
Reddy, V.2
Morley, J.E.3
-
57
-
-
0026557197
-
Purification and structural analysis of hippocampal cholinergic neurostimulating peptide
-
10.1016/0006-8993(92)90465-L
-
K Ojika S Kojima Y Ueki 1992 Purification and structural analysis of hippocampal cholinergic neurostimulating peptide Brain Res 572 164 171 10.1016/0006-8993(92)90465-L
-
(1992)
Brain Res
, vol.572
, pp. 164-171
-
-
Ojika, K.1
Kojima, S.2
Ueki, Y.3
-
58
-
-
0032889093
-
Increased expression of hippocampal cholinergic neurostimulating peptide-related components and their messenger RNAs in the hippocampus of aged senescence-accelerated mice
-
10.1016/S0306-4522(98)00215-2
-
N Matsukawa I Tooyama H Kimura 1999 Increased expression of hippocampal cholinergic neurostimulating peptide-related components and their messenger RNAs in the hippocampus of aged senescence-accelerated mice Neuroscience 88 79 92 10.1016/S0306-4522(98)00215-2
-
(1999)
Neuroscience
, vol.88
, pp. 79-92
-
-
Matsukawa, N.1
Tooyama, I.2
Kimura, H.3
-
59
-
-
34447553376
-
Differential expression of HCNP-related antigens in hippocampus in senescence-accelerated mice
-
10.1016/j.brainres.2007.05.013
-
K Yamada N Matsukawa H Yuasa 2007 Differential expression of HCNP-related antigens in hippocampus in senescence-accelerated mice Brain Res 1158 169 175 10.1016/j.brainres.2007.05.013
-
(2007)
Brain Res
, vol.1158
, pp. 169-175
-
-
Yamada, K.1
Matsukawa, N.2
Yuasa, H.3
-
60
-
-
0024529369
-
Biochemical changes related to aging in the senescence-accelerated mouse
-
10.1016/0531-5565(89)90034-X
-
Y Nomura BX Wang SB Qi 1989 Biochemical changes related to aging in the senescence-accelerated mouse Exp Gerontol 24 49 55 10.1016/0531-5565(89)90034-X
-
(1989)
Exp Gerontol
, vol.24
, pp. 49-55
-
-
Nomura, Y.1
Wang, B.X.2
Qi, S.B.3
-
61
-
-
0027359849
-
Age-associated changes in superoxide dismutase activity, thiobarbituric acid reactivity and reduced glutathione level in the brain and liver in senescence accelerated mice (SAM): A comparison with ddY mice
-
10.1016/0047-6374(93)90032-M
-
J Liu A Mori 1993 Age-associated changes in superoxide dismutase activity, thiobarbituric acid reactivity and reduced glutathione level in the brain and liver in senescence accelerated mice (SAM): a comparison with ddY mice Mech Ageing Dev 71 23 30 10.1016/0047-6374(93)90032-M
-
(1993)
Mech Ageing Dev
, vol.71
, pp. 23-30
-
-
Liu, J.1
Mori, A.2
-
62
-
-
0029058728
-
The spin-trap N-tert-α-phenyl-butylnitrone prolongs the life span of the senescence accelerated mouse
-
10.1006/bbrc.1995.1889
-
R Edamatsu A Mori L Packer 1995 The spin-trap N-tert-α-phenyl- butylnitrone prolongs the life span of the senescence accelerated mouse Biochem Biophys Res Commun 211 847 849 10.1006/bbrc.1995.1889
-
(1995)
Biochem Biophys Res Commun
, vol.211
, pp. 847-849
-
-
Edamatsu, R.1
Mori, A.2
Packer, L.3
-
63
-
-
0030032553
-
Early and transient increase in oxidative stress in the cerebral cortex of senescence-accelerated mouse
-
10.1016/0047-6374(95)01681-3
-
E Sato N Oda N Ozaki 1996 Early and transient increase in oxidative stress in the cerebral cortex of senescence-accelerated mouse Mech Ageing Dev 86 105 114 10.1016/0047-6374(95)01681-3
-
(1996)
Mech Ageing Dev
, vol.86
, pp. 105-114
-
-
Sato, E.1
Oda, N.2
Ozaki, N.3
-
64
-
-
0030595979
-
Early appearance of abnormality of microperoxisomal enzymes in the cerebral cortex of senescence-accelerated mouse
-
10.1016/S0047-6374(96)01832-5
-
E Sato T Kurokawa N Oda 1996 Early appearance of abnormality of microperoxisomal enzymes in the cerebral cortex of senescence-accelerated mouse Mech Ageing Dev 92 175 184 10.1016/S0047-6374(96)01832-5
-
(1996)
Mech Ageing Dev
, vol.92
, pp. 175-184
-
-
Sato, E.1
Kurokawa, T.2
Oda, N.3
-
65
-
-
0035793477
-
Age-related changes in manganese superoxide dismutase activity in the cerebral cortex of senescence-accelerated prone and resistant mouse
-
10.1016/S0304-3940(00)01755-9
-
T Kurokawa S Asada S Nishitani 2001 Age-related changes in manganese superoxide dismutase activity in the cerebral cortex of senescence-accelerated prone and resistant mouse Neurosci Lett 298 135 138 10.1016/S0304-3940(00)01755- 9
-
(2001)
Neurosci Lett
, vol.298
, pp. 135-138
-
-
Kurokawa, T.1
Asada, S.2
Nishitani, S.3
-
66
-
-
0033989482
-
Age-dependent changes in lipid peroxide levels in peripheral organs, but not in brain, in senescence-accelerated mice
-
10.1016/S0304-3940(99)00907-6
-
S Matsugo T Kitagawa S Minami 2000 Age-dependent changes in lipid peroxide levels in peripheral organs, but not in brain, in senescence- accelerated mice Neurosci Lett 278 105 108 10.1016/S0304-3940(99)00907-6
-
(2000)
Neurosci Lett
, vol.278
, pp. 105-108
-
-
Matsugo, S.1
Kitagawa, T.2
Minami, S.3
-
67
-
-
0142075277
-
Brain lipid hydroperoxide level increases in senescence-accelerated mice at an early age
-
10.1016/S0304-3940(03)00827-9
-
F Yasui M Ishibashi S Matsugo 2003 Brain lipid hydroperoxide level increases in senescence-accelerated mice at an early age Neurosci Lett 350 66 68 10.1016/S0304-3940(03)00827-9
-
(2003)
Neurosci Lett
, vol.350
, pp. 66-68
-
-
Yasui, F.1
Ishibashi, M.2
Matsugo, S.3
-
68
-
-
0036252301
-
Melatonin reduces oxidative damage of neural lipids and proteins in senescence-accelerated mouse
-
10.1016/S0197-4580(02)00005-2
-
Y Okatani A Wakatsuki RJ Reiter 2002 Melatonin reduces oxidative damage of neural lipids and proteins in senescence-accelerated mouse Neurobiol Aging 23 639 644 10.1016/S0197-4580(02)00005-2
-
(2002)
Neurobiol Aging
, vol.23
, pp. 639-644
-
-
Okatani, Y.1
Wakatsuki, A.2
Reiter, R.J.3
-
69
-
-
33745245682
-
Elevated oxidative stress in the brain of senescence-accelerated mice
-
10.1007/s10522-005-6041-2
-
Ó Álvarez-Garcia I Vega-Naredo V Sierra 2006 Elevated oxidative stress in the brain of senescence-accelerated mice Biogerontology 7 43 52 10.1007/s10522-005-6041-2
-
(2006)
Biogerontology
, vol.7
, pp. 43-52
-
-
Álvarez-Garcia, Ó.1
Vega-Naredo, I.2
Sierra, V.3
-
70
-
-
33646493486
-
Changes in oxidative stress parameters and neurodegeneration markers in the brain of the senescence-accelerated mice SAMP-8
-
10.1016/j.exger.2006.01.015
-
FX Sureda J Gutierrez-Cuesta M Romeu 2006 Changes in oxidative stress parameters and neurodegeneration markers in the brain of the senescence-accelerated mice SAMP-8 Exp Gerontol 41 360 367 10.1016/j.exger.2006. 01.015
-
(2006)
Exp Gerontol
, vol.41
, pp. 360-367
-
-
Sureda, F.X.1
Gutierrez-Cuesta, J.2
Romeu, M.3
-
71
-
-
27644465539
-
Hyperphosphorylation of microtubule-associated protein tau in senescence-accelerated mouse (SAM)
-
10.1016/j.mad.2005.07.008
-
AM Canudas J Gutierrez-Cuesta MI Rodríguez 2005 Hyperphosphorylation of microtubule-associated protein tau in senescence-accelerated mouse (SAM) Mech Ageing Dev 126 1300 1304 10.1016/j.mad.2005.07.008
-
(2005)
Mech Ageing Dev
, vol.126
, pp. 1300-1304
-
-
Canudas, A.M.1
Gutierrez-Cuesta, J.2
Rodríguez, M.I.3
-
72
-
-
6944220226
-
Comparison of thiol redox state of mitochondria and homogenates of various tissues between two strains of mice with different longevities
-
10.1016/j.exger.2004.08.014
-
I Rebrin RS Sohal 2004 Comparison of thiol redox state of mitochondria and homogenates of various tissues between two strains of mice with different longevities Exp Gerontol 39 1513 1519 10.1016/j.exger.2004.08.014
-
(2004)
Exp Gerontol
, vol.39
, pp. 1513-1519
-
-
Rebrin, I.1
Sohal, R.S.2
-
73
-
-
0031029393
-
Free radical oxidation of brain proteins in accelerated senescence and its modulation by N-tert-butyl-α-phenylnitrone
-
10.1073/pnas.94.2.674
-
DA Butterfield BJ Howard S Yatin 1997 Free radical oxidation of brain proteins in accelerated senescence and its modulation by N-tert-butyl-α- phenylnitrone Proc Natl Acad Sci USA 94 674 678 10.1073/pnas.94.2.674
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 674-678
-
-
Butterfield, D.A.1
Howard, B.J.2
Yatin, S.3
-
74
-
-
0036905921
-
Amyloid β-peptide (1-42)-induced oxidative stress and neurotoxicity: Implications for neurodegeneration in Alzheimer's brain. A review
-
10.1080/1071576021000049890
-
DA Butterfield 2002 Amyloid β-peptide (1-42)-induced oxidative stress and neurotoxicity: implications for neurodegeneration in Alzheimer's brain. A review Free Radic Res 36 1307 1313 10.1080/1071576021000049890
-
(2002)
Free Radic Res
, vol.36
, pp. 1307-1313
-
-
Butterfield, D.A.1
-
75
-
-
3242715959
-
Antisense directed at the Aβ region of APP decreases brain oxidative markers in aged senescence accelerated mice
-
10.1016/j.brainres.2004.05.048
-
HF Poon G Joshi R Sultana 2004 Antisense directed at the Aβ region of APP decreases brain oxidative markers in aged senescence accelerated mice Brain Res 1018 86 89 10.1016/j.brainres.2004.05.048
-
(2004)
Brain Res
, vol.1018
, pp. 86-89
-
-
Poon, H.F.1
Joshi, G.2
Sultana, R.3
-
76
-
-
0037342554
-
The antioxidants α-lipoic acid and N-acetylcysteine reverse memory impairment and brain oxidative stress in aged SAMP8 mice
-
10.1046/j.1471-4159.2003.01580.x
-
SA Farr HF Poon D Dogrukol-Ak 2003 The antioxidants α-lipoic acid and N-acetylcysteine reverse memory impairment and brain oxidative stress in aged SAMP8 mice J Neurochem 84 1173 1183 10.1046/j.1471-4159.2003.01580.x
-
(2003)
J Neurochem
, vol.84
, pp. 1173-1183
-
-
Farr, S.A.1
Poon, H.F.2
Dogrukol-Ak, D.3
-
77
-
-
33847688564
-
Impairment of CREB phosphorylation in the hippocampal CA1 region of the senescence-accelerated mouse (SAM) P8
-
10.1016/j.brainres.2006.08.026
-
K Tomobe Y Okuma Y Nomura 2007 Impairment of CREB phosphorylation in the hippocampal CA1 region of the senescence-accelerated mouse (SAM) P8 Brain Res 1141 214 217 10.1016/j.brainres.2006.08.026
-
(2007)
Brain Res
, vol.1141
, pp. 214-217
-
-
Tomobe, K.1
Okuma, Y.2
Nomura, Y.3
-
78
-
-
5644220940
-
2+current by 4-hydroxynonenal in dentate granule cells
-
10.1248/bpb.27.174
-
2+current by 4-hydroxynonenal in dentate granule cells Biol Pharm Bull 27 174 179 10.1248/bpb.27.174
-
(2004)
Biol Pharm Bull
, vol.27
, pp. 174-179
-
-
Akaishi, T.1
Nakazawa, K.2
Sato, K.3
-
79
-
-
0034279245
-
2+/calmodulin-dependent protein kinase type IV/Gr-deficient mice
-
2+/calmodulin- dependent protein kinase type IV/Gr-deficient mice J Neurosci 20 6459 6472
-
(2000)
J Neurosci
, vol.20
, pp. 6459-6472
-
-
Ho, N.1
Liauw, J.A.2
Blaeser, F.3
-
80
-
-
0030424506
-
Alterations in calcium antagonist receptors and calcuium content in senescent brain and attenuation by nimodipine and nicardipine
-
S Yamada S Uchida T Ohkura 1996 Alterations in calcium antagonist receptors and calcuium content in senescent brain and attenuation by nimodipine and nicardipine J Pharmacol Exp Ther 277 721 727
-
(1996)
J Pharmacol Exp Ther
, vol.277
, pp. 721-727
-
-
Yamada, S.1
Uchida, S.2
Ohkura, T.3
-
81
-
-
0031974019
-
Mitochondrial dysfunction in the senescence accelerated mouse (SAM)
-
10.1016/S0891-5849(97)00164-0
-
H Nakahara T Kanno Y Inai 1998 Mitochondrial dysfunction in the senescence accelerated mouse (SAM) Free Radic Biol Med 24 85 92 10.1016/S0891-5849(97)00164-0
-
(1998)
Free Radic Biol Med
, vol.24
, pp. 85-92
-
-
Nakahara, H.1
Kanno, T.2
Inai, Y.3
-
82
-
-
0032566620
-
An early stage mechanism of the age-associated mitochondrial dysfunction in the brain of SAMP8 mice; An age-associated neurodegeneration animal model
-
10.1016/S0304-3940(98)00646-6
-
T Nishikawa JA Takahashi Y Fujibayashi 1998 An early stage mechanism of the age-associated mitochondrial dysfunction in the brain of SAMP8 mice; an age-associated neurodegeneration animal model Neurosci Lett 254 69 72 10.1016/S0304-3940(98)00646-6
-
(1998)
Neurosci Lett
, vol.254
, pp. 69-72
-
-
Nishikawa, T.1
Takahashi, J.A.2
Fujibayashi, Y.3
-
83
-
-
0032566721
-
Increased mitochondrial DNA deletion in the brain of SAMP8, a mouse model for spontaneous oxidative stress bain
-
10.1016/S0304-3940(98)00667-3
-
Y Fujibayashi S Yamamoto A Waki 1998 Increased mitochondrial DNA deletion in the brain of SAMP8, a mouse model for spontaneous oxidative stress bain Neurosci Lett 254 109 112 10.1016/S0304-3940(98)00667-3
-
(1998)
Neurosci Lett
, vol.254
, pp. 109-112
-
-
Fujibayashi, Y.1
Yamamoto, S.2
Waki, A.3
-
84
-
-
34249909201
-
Mitochondrial dysfunction in platelets and hippocampi of senescence-accelerated mice
-
10.1007/s10863-007-9077-y
-
J Xu C Shi Q Li 2007 Mitochondrial dysfunction in platelets and hippocampi of senescence-accelerated mice J Bioenerg Biomembr 39 195 202 10.1007/s10863-007-9077-y
-
(2007)
J Bioenerg Biomembr
, vol.39
, pp. 195-202
-
-
Xu, J.1
Shi, C.2
Li, Q.3
-
85
-
-
0027301454
-
Age-related changes in barrier function in mouse brain I. Accelerated age-related increase of brain transfer of serum albumin in accelerated senescence prone SAM-P/8 mice with deficits in learning and memory
-
10.1016/0167-4943(93)90035-G
-
M Ueno I Akiguchi H Yagi 1993 Age-related changes in barrier function in mouse brain I. Accelerated age-related increase of brain transfer of serum albumin in accelerated senescence prone SAM-P/8 mice with deficits in learning and memory Arch Gerontol Geriatr 16 233 248 10.1016/0167-4943(93)90035-G
-
(1993)
Arch Gerontol Geriatr
, vol.16
, pp. 233-248
-
-
Ueno, M.1
Akiguchi, I.2
Yagi, H.3
-
86
-
-
0029984347
-
Immunocytochemical evaluation of the blood-brain barrier to endogenous albumin in the olfactory bulb and pons of senescence-accelerated mice (SAM)
-
10.1007/BF01462293
-
M Ueno DH Dobrogowska AW Vorbrodt 1996 Immunocytochemical evaluation of the blood-brain barrier to endogenous albumin in the olfactory bulb and pons of senescence-accelerated mice (SAM) Histochem Cell Biol 105 203 212 10.1007/BF01462293
-
(1996)
Histochem Cell Biol
, vol.105
, pp. 203-212
-
-
Ueno, M.1
Dobrogowska, D.H.2
Vorbrodt, A.W.3
-
87
-
-
0031056580
-
Age-related changes in the brain transfer of blood-borne horseradish peroxidase in the hippocampus of senescence-accelerated mouse
-
10.1007/s004010050609
-
M Ueno I Akiguchi M Hosokawa 1997 Age-related changes in the brain transfer of blood-borne horseradish peroxidase in the hippocampus of senescence-accelerated mouse Acta Neuropathol 93 233 240 10.1007/s004010050609
-
(1997)
Acta Neuropathol
, vol.93
, pp. 233-240
-
-
Ueno, M.1
Akiguchi, I.2
Hosokawa, M.3
-
88
-
-
0034473218
-
Permeability of the blood-brain barrier to albumin and insulin in the young and aged SAMP8 mouse
-
WA Banks SA Farr JE Morley 2000 Permeability of the blood-brain barrier to albumin and insulin in the young and aged SAMP8 mouse J Gerontol Biol Sci 55A B601 B606
-
(2000)
J Gerontol Biol Sci
, vol.55
-
-
Banks, W.A.1
Farr, S.A.2
Morley, J.E.3
-
89
-
-
34548305271
-
Increased permeability of blood-brain barrier on the hippocampus of a murine model of senescence
-
10.1016/j.mad.2007.07.002
-
C Pelegrí AM Canudas JD Valle 2007 Increased permeability of blood-brain barrier on the hippocampus of a murine model of senescence Mech Ageing Dev 128 522 528 10.1016/j.mad.2007.07.002
-
(2007)
Mech Ageing Dev
, vol.128
, pp. 522-528
-
-
Pelegrí, C.1
Canudas, A.M.2
Valle, J.D.3
-
90
-
-
0025076433
-
Age-related deterioration of long term potentiation in the CA3 and CA1 regions of hippocampal slices from the senescence-accelerated mouse
-
10.1016/0167-4943(90)90058-E
-
H Katsuki K Ishihara A Shimada 1990 Age-related deterioration of long term potentiation in the CA3 and CA1 regions of hippocampal slices from the senescence-accelerated mouse Arch Gerontol Geriatr 11 77 83 10.1016/0167- 4943(90)90058-E
-
(1990)
Arch Gerontol Geriatr
, vol.11
, pp. 77-83
-
-
Katsuki, H.1
Ishihara, K.2
Shimada, A.3
-
91
-
-
16244413228
-
D-Serine enhances impaired long-term potentiation in CA1 subfield of hippocampal slices from aged senescence-accelerated mouse prone/8
-
10.1016/j.neulet.2004.12.033
-
S Yang H Qiao L Wen 2005 d-Serine enhances impaired long-term potentiation in CA1 subfield of hippocampal slices from aged senescence-accelerated mouse prone/8 Neurosci Lett 379 7 12 10.1016/j.neulet. 2004.12.033
-
(2005)
Neurosci Lett
, vol.379
, pp. 7-12
-
-
Yang, S.1
Qiao, H.2
Wen, L.3
-
92
-
-
0030586968
-
Age-related increase in nitric oxide synthase activity in senescence accelerated mouse brain and the effect of long-term administration of superoxide radical scavenger
-
10.1016/0047-6374(96)01743-5
-
K Inada I Yokoi H Kabuto 1996 Age-related increase in nitric oxide synthase activity in senescence accelerated mouse brain and the effect of long-term administration of superoxide radical scavenger Mech Ageing Dev 89 95 102 10.1016/0047-6374(96)01743-5
-
(1996)
Mech Ageing Dev
, vol.89
, pp. 95-102
-
-
Inada, K.1
Yokoi, I.2
Kabuto, H.3
-
93
-
-
0029826118
-
Prevention of hyperoxia-induced alterations in synaptosomal membrane-associated proteins by N-tert butyl-alpha-phenylnitrone and 4-hydroxy-2, 2, 6, 6-tetramethylpiperidine-1-oxyl (Tempol)
-
DJ Howard S Yatin K Hensley 1996 Prevention of hyperoxia-induced alterations in synaptosomal membrane-associated proteins by N-tert butyl-alpha-phenylnitrone and 4-hydroxy-2, 2, 6, 6-tetramethylpiperidine-1-oxyl (Tempol) J Neurochem 67 2045 2050
-
(1996)
J Neurochem
, vol.67
, pp. 2045-2050
-
-
Howard, D.J.1
Yatin, S.2
Hensley, K.3
-
94
-
-
2942659505
-
Quantitative proteomics analysis of spectfic protein expression and oxidative modification in aged senescence-accelerated-prone 8 mice brain
-
10.1016/j.neuroscience.2004.04.046
-
HF Poon A Castegna SA Farr 2004 Quantitative proteomics analysis of spectfic protein expression and oxidative modification in aged senescence-accelerated-prone 8 mice brain Neuroscience 126 915 926 10.1016/j.neuroscience.2004.04.046
-
(2004)
Neuroscience
, vol.126
, pp. 915-926
-
-
Poon, H.F.1
Castegna, A.2
Farr, S.A.3
-
95
-
-
22744455017
-
Proteomic identification of less oxidized proteins in aged senescence-accelerated mice following administration of antisense oligonucleotide directed at Aβ region of amyloid precursor protein
-
1. 10.1016/j.molbrainres.2005.02.020
-
HF Poon SA Farr WA Banks 2005 Proteomic identification of less oxidized proteins in aged senescence-accelerated mice following administration of antisense oligonucleotide directed at Aβ region of amyloid precursor protein Brain Res Mol Brain Res 138 1 8 16 10.1016/j.molbrainres.2005.02.020
-
(2005)
Brain Res Mol Brain Res
, vol.138
, pp. 8-16
-
-
Poon, H.F.1
Farr, S.A.2
Banks, W.A.3
-
96
-
-
0028352963
-
Expression of neurotropine genes in the brain of senescence-accelerated mouse (SAM) during postnatal development
-
10.1016/0006-8993(94)91408-7
-
Y Kaisho M Miyamoto O Shiho 1994 Expression of neurotropine genes in the brain of senescence-accelerated mouse (SAM) during postnatal development Brain Res 647 139 144 10.1016/0006-8993(94)91408-7
-
(1994)
Brain Res
, vol.647
, pp. 139-144
-
-
Kaisho, Y.1
Miyamoto, M.2
Shiho, O.3
-
97
-
-
0033543584
-
Changes in membrane fatty acids and delta-9 desaturase in senescence accelerated (SAMP8) mouse hippocampus with aging
-
10.1016/S0024-3205(99)00414-2
-
VB Kumar K Vyas M Buddhiraju 1999 Changes in membrane fatty acids and delta-9 desaturase in senescence accelerated (SAMP8) mouse hippocampus with aging Life Sci 65 1657 1662 10.1016/S0024-3205(99)00414-2
-
(1999)
Life Sci
, vol.65
, pp. 1657-1662
-
-
Kumar, V.B.1
Vyas, K.2
Buddhiraju, M.3
-
98
-
-
0033603608
-
Alzheimer's disease-related gene expression in the brain of senescence accelerated mouse
-
10.1016/S0304-3940(99)00396-1
-
X Wei Y Zhang J Zhou 1999 Alzheimer's disease-related gene expression in the brain of senescence accelerated mouse Neurosci Lett 268 139 142 10.1016/S0304-3940(99)00396-1
-
(1999)
Neurosci Lett
, vol.268
, pp. 139-142
-
-
Wei, X.1
Zhang, Y.2
Zhou, J.3
-
99
-
-
0034674343
-
Identification of age-dependent changes in expression of senescence accelerated mouse (SAMP8) hippocampal proteins by expression array analysis
-
10.1006/bbrc.2000.2719
-
VB Kumar MW Franko SA Farr 2000 Identification of age-dependent changes in expression of senescence accelerated mouse (SAMP8) hippocampal proteins by expression array analysis Biochem Biophys Res Commun 272 657 661 10.1006/bbrc.2000.2719
-
(2000)
Biochem Biophys Res Commun
, vol.272
, pp. 657-661
-
-
Kumar, V.B.1
Franko, M.W.2
Farr, S.A.3
-
100
-
-
0038718475
-
Age-related alterations in the expression of glial cell line-derived neurotrophic factor in the senescence-accelerated mouse brain
-
10.1254/jphs.92.28
-
H Miyazaki Y Okuma J Nomura 2003 Age-related alterations in the expression of glial cell line-derived neurotrophic factor in the senescence-accelerated mouse brain J Pharmacol Sci 92 28 34 10.1254/jphs.92.28
-
(2003)
J Pharmacol Sci
, vol.92
, pp. 28-34
-
-
Miyazaki, H.1
Okuma, Y.2
Nomura, J.3
-
101
-
-
33847168242
-
Differential gene expression profiles in the hippocampus of senescence-accelerated mouse
-
10.1016/j.neurobiolaging.2006.02.004
-
X-R Cheng W-X Zhou Y-X Zhang 2007 Differential gene expression profiles in the hippocampus of senescence-accelerated mouse Neurobiol Aging 28 497 506 10.1016/j.neurobiolaging.2006.02.004
-
(2007)
Neurobiol Aging
, vol.28
, pp. 497-506
-
-
Cheng, X.-R.1
Zhou, W.-X.2
Zhang, Y.-X.3
-
102
-
-
33744466467
-
Altered gene expression in the brain of senescence accelerated mouse SAMP8
-
10.1016/S0531-5131(03)01606-6
-
R Takahashi S Goto 2004 Altered gene expression in the brain of senescence accelerated mouse SAMP8 Int Congr Ser 1260 85 90 10.1016/S0531- 5131(03)01606-6
-
(2004)
Int Congr ser
, vol.1260
, pp. 85-90
-
-
Takahashi, R.1
Goto, S.2
-
103
-
-
26244456297
-
The senescence-accelerated prone mouse (SAMP8): A model of age-related cognitive decline with relevance to alterations of the gene expression and protein abnormalities in Alzheimer's disease
-
10. 10.1016/j.exger.2005.05.007
-
DA Butterfield HF Poon 2005 The senescence-accelerated prone mouse (SAMP8): a model of age-related cognitive decline with relevance to alterations of the gene expression and protein abnormalities in Alzheimer's disease Exp Gerontol 40 10 774 783 10.1016/j.exger.2005.05.007
-
(2005)
Exp Gerontol
, vol.40
, pp. 774-783
-
-
Butterfield, D.A.1
Poon, H.F.2
-
104
-
-
33745876102
-
Mechanisms of aging in senescence-accelerated mice
-
6. 10.1186/gb-2005-6-6-r48
-
TA Carter JA Greenhal S Yoshida 2005 Mechanisms of aging in senescence-accelerated mice Genome Biol 6 6 R48 10.1186/gb-2005-6-6-r48
-
(2005)
Genome Biol
, vol.6
, pp. 48
-
-
Carter, T.A.1
Greenhal, J.A.2
Yoshida, S.3
-
105
-
-
62349128921
-
Genetic study of learning and memory deficits in SAMP8 mice
-
10.1016/S0531-5131(03)01680-7
-
K Tomobe M Isobe M Sawada 2004 Genetic study of learning and memory deficits in SAMP8 mice Int Congr Ser 1260 353 356 10.1016/S0531-5131(03)01680-7
-
(2004)
Int Congr ser
, vol.1260
, pp. 353-356
-
-
Tomobe, K.1
Isobe, M.2
Sawada, M.3
-
106
-
-
0026776419
-
Inbred SAM-P/10 as a mouse model of spontaneous, inherited brain atrophy
-
4. 10.1097/00005072-199207000-00006
-
A Shimada A Ohta I Akiguchi 1992 Inbred SAM-P/10 as a mouse model of spontaneous, inherited brain atrophy J Neuropathol Exp Neurol 51 4 440 450 10.1097/00005072-199207000-00006
-
(1992)
J Neuropathol Exp Neurol
, vol.51
, pp. 440-450
-
-
Shimada, A.1
Ohta, A.2
Akiguchi, I.3
-
107
-
-
0027467103
-
Age-related deterioration on conditional avoidance task in the SAM-P/10 mouse, an animal model of spontaneous brain atrophy
-
10.1016/0006-8993(93)91467-7
-
A Shimada A Ohta I Akiguchi 1993 Age-related deterioration on conditional avoidance task in the SAM-P/10 mouse, an animal model of spontaneous brain atrophy Brain Res 608 266 272 10.1016/0006-8993(93)91467-7
-
(1993)
Brain Res
, vol.608
, pp. 266-272
-
-
Shimada, A.1
Ohta, A.2
Akiguchi, I.3
-
108
-
-
0034646887
-
Learning deficiency and alterations in acetylcholine receptors and protein kinase C in the brain of senescence-accelerated mouse (SAM)-P10
-
10.1016/S0047-6374(00)00103-2
-
Y Okuma T Murayama KK Tha 2000 Learning deficiency and alterations in acetylcholine receptors and protein kinase C in the brain of senescence-accelerated mouse (SAM)-P10 Mech Ageing Dev 114 191 199 10.1016/S0047-6374(00)00103-2
-
(2000)
Mech Ageing Dev
, vol.114
, pp. 191-199
-
-
Okuma, Y.1
Murayama, T.2
Tha, K.K.3
-
109
-
-
84964517626
-
Age-related decrease in spontaneity observed in senescence-accelerated mice (SAMP10) and the involvement of the dopaminergic system in behavioral disorders
-
10.1016/S0531-5131(03)01671-6
-
H Takahashi J Sakamoto H Ohta 2004 Age-related decrease in spontaneity observed in senescence-accelerated mice (SAMP10) and the involvement of the dopaminergic system in behavioral disorders Int Congr Ser 1260 309 314 10.1016/S0531-5131(03)01671-6
-
(2004)
Int Congr ser
, vol.1260
, pp. 309-314
-
-
Takahashi, H.1
Sakamoto, J.2
Ohta, H.3
-
110
-
-
0028333590
-
Localization of atrophy-prone areas in the aging mouse brain: Comparison between the brain atrophy model SAM-P/10 and the normal control SAN-R/1
-
10.1016/0306-4522(94)90290-9
-
A Shimada M Hosokawa A Ohta 1994 Localization of atrophy-prone areas in the aging mouse brain: comparison between the brain atrophy model SAM-P/10 and the normal control SAN-R/1 Neuroscience 59 859 869 10.1016/0306-4522(94)90290-9
-
(1994)
Neuroscience
, vol.59
, pp. 859-869
-
-
Shimada, A.1
Hosokawa, M.2
Ohta, A.3
-
111
-
-
0036905781
-
Age-related progressive neuronal DNA damage associated with cerebral degeneration in a mouse model of accelerated senescence
-
A Shimada H Keino M Sato 2002 Age-related progressive neuronal DNA damage associated with cerebral degeneration in a mouse model of accelerated senescence J Gerontol Biol Sci 57A B415 B421
-
(2002)
J Gerontol Biol Sci
, vol.57
-
-
Shimada, A.1
Keino, H.2
Sato, M.3
-
112
-
-
0034028985
-
Neuronal nuclear DNA fragmentation in the aged canine brain: Apotosis or nuclear DNA fragility?
-
10.1007/s004010051142
-
D Borras M Pumarola I Ferrer 2000 Neuronal nuclear DNA fragmentation in the aged canine brain: apotosis or nuclear DNA fragility? Acta Neuropathol 99 402 408 10.1007/s004010051142
-
(2000)
Acta Neuropathol
, vol.99
, pp. 402-408
-
-
Borras, D.1
Pumarola, M.2
Ferrer, I.3
-
113
-
-
2642680857
-
Alzheimer disease: DNA fragmentation indicates increased neuronal vulnerability, but not apotosis
-
C Stadelmann W Bruck C Bancher 1998 Alzheimer disease: DNA fragmentation indicates increased neuronal vulnerability, but not apotosis J Neuropathol Exp Neurol 57 456 464
-
(1998)
J Neuropathol Exp Neurol
, vol.57
, pp. 456-464
-
-
Stadelmann, C.1
Bruck, W.2
Bancher, C.3
-
114
-
-
0037448153
-
Age-related loss of synapses in the frontal cortex of SAMP10 mouse: A model of cerebral degeneration
-
10.1002/syn.10209
-
A Shimada H Keino M Satoh 2003 Age-related loss of synapses in the frontal cortex of SAMP10 mouse: a model of cerebral degeneration Synapse 48 198 204 10.1002/syn.10209
-
(2003)
Synapse
, vol.48
, pp. 198-204
-
-
Shimada, A.1
Keino, H.2
Satoh, M.3
-
115
-
-
33644887498
-
Apical vulnerability to dendritic retraction in prefrontal neurons of aging SAMP10 mouse: A model of cerebral degeneration
-
10.1111/j.1365-2990.2006.00632.x
-
A Shimada M Tsuzuki H Keino 2006 Apical vulnerability to dendritic retraction in prefrontal neurons of aging SAMP10 mouse: a model of cerebral degeneration Neuropathol Appl Neurobiol 32 1 14 10.1111/j.1365-2990.2006.00632.x
-
(2006)
Neuropathol Appl Neurobiol
, vol.32
, pp. 1-14
-
-
Shimada, A.1
Tsuzuki, M.2
Keino, H.3
-
116
-
-
38149030026
-
Limbic structures are prone to age-related impairments in proteasome activity and neuronal ubiquitinated inclusions in SAMP10 mouse: A model of cerebral degeneration
-
A Shimada H Keino Y Chiba 2008 Limbic structures are prone to age-related impairments in proteasome activity and neuronal ubiquitinated inclusions in SAMP10 mouse: a model of cerebral degeneration Neuropathol Appl Neurobiol 34 33 51
-
(2008)
Neuropathol Appl Neurobiol
, vol.34
, pp. 33-51
-
-
Shimada, A.1
Keino, H.2
Chiba, Y.3
-
117
-
-
36448941228
-
Involvement of pro-inflammatory cytokines and microglia in an age-associated neurodegeneration model, the SAMP10 mouse
-
10.1016/j.brainres.2007.09.021
-
N Kumagai Y Chiba M Hosono 2007 Involvement of pro-inflammatory cytokines and microglia in an age-associated neurodegeneration model, the SAMP10 mouse Brain Res 1185 75 85 10.1016/j.brainres.2007.09.021
-
(2007)
Brain Res
, vol.1185
, pp. 75-85
-
-
Kumagai, N.1
Chiba, Y.2
Hosono, M.3
-
118
-
-
0031589529
-
Sphingomyelinase activity is enhanced in cerebral cortex of senescence-accelerated mouse-P/10 with advancing age
-
10.1006/bbrc.1997.7133
-
SS Kim MS Kang YM Choi 1997 Sphingomyelinase activity is enhanced in cerebral cortex of senescence-accelerated mouse-P/10 with advancing age Biochem Biophys Res Commun 237 583 587 10.1006/bbrc.1997.7133
-
(1997)
Biochem Biophys Res Commun
, vol.237
, pp. 583-587
-
-
Kim, S.S.1
Kang, M.S.2
Choi, Y.M.3
-
119
-
-
0034694804
-
Deficiencies of hippocampal Zn and ZnT3 accelerate brain aging of mice
-
10.1006/bbrc.2000.3946
-
T Saito K Takahashi N Nakagawa 2000 Deficiencies of hippocampal Zn and ZnT3 accelerate brain aging of mice Biochem Biophys Res Commun 279 505 511 10.1006/bbrc.2000.3946
-
(2000)
Biochem Biophys Res Commun
, vol.279
, pp. 505-511
-
-
Saito, T.1
Takahashi, K.2
Nakagawa, N.3
-
120
-
-
0033822358
-
Depressive behavior and alterations in receptors for dopamine and 5-hydroxytryptamine in the brain of the senescence-accelerated mouse (SAM)-P10
-
10.1254/jjp.83.312
-
Y Onodera R Watanabe KK Tha 2000 Depressive behavior and alterations in receptors for dopamine and 5-hydroxytryptamine in the brain of the senescence-accelerated mouse (SAM)-P10 Jpn J Pharmacol 83 312 318 10.1254/jjp.83.312
-
(2000)
Jpn J Pharmacol
, vol.83
, pp. 312-318
-
-
Onodera, Y.1
Watanabe, R.2
Tha, K.K.3
-
121
-
-
0036389727
-
Bcl-2 linked apotosis due to increase in NO synthase in brain of SAMP10
-
10.1016/S0006-291X(02)02155-1
-
T Numata T Saito K Maekawa 2002 Bcl-2 linked apotosis due to increase in NO synthase in brain of SAMP10 Biochem Biophys Res Commun 297 517 522 10.1016/S0006-291X(02)02155-1
-
(2002)
Biochem Biophys Res Commun
, vol.297
, pp. 517-522
-
-
Numata, T.1
Saito, T.2
Maekawa, K.3
-
122
-
-
0032561718
-
Hyperexcitability of amygdale neurons of senescence-accelareted mouse revealed by electrical and optical recordings in an in vitro slice preparation
-
10.1016/S0006-8993(98)00968-8
-
H Nakanishi M Miyazaki N Takai 1998 Hyperexcitability of amygdale neurons of senescence-accelareted mouse revealed by electrical and optical recordings in an in vitro slice preparation Brain Res 812 142 149 10.1016/S0006-8993(98) 00968-8
-
(1998)
Brain Res
, vol.812
, pp. 142-149
-
-
Nakanishi, H.1
Miyazaki, M.2
Takai, N.3
-
123
-
-
0026718001
-
Age-related changes in LFA-1 expression, cell adhesion, and PHA-induced proliferation by lymphocytes from senescence-accelerated mouse (SAM)-P/8 and SAM-R/1 substrains
-
10.1016/0008-8749(92)90162-I
-
DC Powers JE Morley JF Flood 1992 Age-related changes in LFA-1 expression, cell adhesion, and PHA-induced proliferation by lymphocytes from senescence-accelerated mouse (SAM)-P/8 and SAM-R/1 substrains Cell Immunol 141 444 456 10.1016/0008-8749(92)90162-I
-
(1992)
Cell Immunol
, vol.141
, pp. 444-456
-
-
Powers, D.C.1
Morley, J.E.2
Flood, J.F.3
-
124
-
-
0027969281
-
Defects of immune cells in the senescence-accelerated mouse: A model for learning and memory deficits in the aged
-
10.1006/cimm.1994.1205
-
Y Abe M Yuasa Y Kajiwara 1994 Defects of immune cells in the senescence-accelerated mouse: a model for learning and memory deficits in the aged Cell Immunol 157 59 69 10.1006/cimm.1994.1205
-
(1994)
Cell Immunol
, vol.157
, pp. 59-69
-
-
Abe, Y.1
Yuasa, M.2
Kajiwara, Y.3
-
125
-
-
13244276460
-
Epigenetic mechanisms in memory formation
-
10.1038/nrn1604
-
J Leverson JD Sweatt 2005 Epigenetic mechanisms in memory formation Nat Rev Neurobiol 6 108 118 10.1038/nrn1604
-
(2005)
Nat Rev Neurobiol
, vol.6
, pp. 108-118
-
-
Leverson, J.1
Sweatt, J.D.2
-
126
-
-
34248523169
-
Recovery of learning and memory is associated with chromatin remodeling
-
10.1038/nature05772
-
A Fischer F Sananbenesi X Wang 2007 Recovery of learning and memory is associated with chromatin remodeling Nature 447 178 182 10.1038/nature05772
-
(2007)
Nature
, vol.447
, pp. 178-182
-
-
Fischer, A.1
Sananbenesi, F.2
Wang, X.3
-
127
-
-
40749105508
-
Variation in DNA elucidate molecular networks that cause disease
-
10.1038/nature06757
-
Y Chen J Zhu PY Lum 2008 Variation in DNA elucidate molecular networks that cause disease Nature 452 429 435 10.1038/nature06757
-
(2008)
Nature
, vol.452
, pp. 429-435
-
-
Chen, Y.1
Zhu, J.2
Lum, P.Y.3
-
128
-
-
41349095280
-
Genetics of gene expression and its effect on disease
-
10.1038/nature06758
-
V Emilsson G Thorleifsson B Zhang 2008 Genetics of gene expression and its effect on disease Nature 452 423 428 10.1038/nature06758
-
(2008)
Nature
, vol.452
, pp. 423-428
-
-
Emilsson, V.1
Thorleifsson, G.2
Zhang, B.3
|