Caspase-6 activity in the CA1 region of the hippocampus induces age-dependent memory impairment

Cell Death and Differentiation

Volumn 21, Issue 5, 2014, Pages 696-706

  Leblanc, A C ^a,b   Ramcharitar, J ^a,b   Afonso, V ^a,b   Hamel, E ^b,c   Bennett, D A ^d,e   Pakavathkumar, P ^a,b   Albrecht, S ^f  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c MCGILL UNIVERSITY   (Canada)

^d RUSH UNIVERSITY MEDICAL CENTER   (United States)

^e RUSH UNIVERSITY MEDICAL CENTER   (United States)

^f MONTREAL CHILDREN S HOSPITAL   (Canada)

Author keywords

aging; Alzheimer disease; Caspase 6; cognitive impairment; neurodegeneration

Indexed keywords

CASPASE 6; GLIAL FIBRILLARY ACIDIC PROTEIN; SYNAPTOPHYSIN; TAU PROTEIN; TUBULIN;

ADULT; AGE; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DECLARATIVE MEMORY; ENZYME ACTIVATION; ENZYME ACTIVITY; EPISODIC MEMORY; FEMALE; HIPPOCAMPAL CA1 REGION; HUMAN; HUMAN TISSUE; MALE; MEMORY CONSOLIDATION; MEMORY DISORDER; MENTAL PERFORMANCE; MOUSE; NERVE CELL DEGENERATION; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; REFERENCE MEMORY; SEMANTIC MEMORY; SPATIAL MEMORY; VERY ELDERLY; WORKING MEMORY; ALZHEIMER DISEASE; ANIMAL; BIOSYNTHESIS; DISEASE MODEL; ENZYMOLOGY; HIPPOCAMPUS; MEMORY; METABOLISM; NERVE CELL; PHYSIOLOGY; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

AGE FACTORS; ALZHEIMER DISEASE; ANIMALS; CASPASE 6; DISEASE MODELS, ANIMAL; HIPPOCAMPUS; HUMANS; MALE; MEMORY; MEMORY DISORDERS; MICE; MICE, TRANSGENIC; NEURONS; SIGNAL TRANSDUCTION;

EID: 84898034402     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2013.194     Document Type: Article

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