Identification of caspase-6-mediated processing of the valosin containing protein (p97) in Alzheimer's disease: A novel link to dysfunction in ubiquitin proteasome system-mediated protein degradation

Journal of Neuroscience

Volumn 30, Issue 17, 2010, Pages 6132-6142

  Halawani, Dalia ^a   Tessier, Sylvain ^b   Anzellotti, Dominique ^a   Bennett, David A ^c   Latterichand, Martin ^a,d   LeBlanc, Andréa C ^a,e  

^a MCGILL UNIVERSITY   (Canada)

^b CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

^c RUSH UNIVERSITY MEDICAL CENTER   (United States)

^d Proteogenomics Research Institute for Systems Medicine   (United States)

^e MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; CASPASE 3; CASPASE 6; CASPASE 7; EPITOPE; PROTEASOME; PROTEIN P97; RECOMBINANT PROTEIN; UBIQUITIN; VALOSIN CONTAINING PROTEIN;

ALZHEIMER DISEASE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BRAIN NERVE CELL; CONTROLLED STUDY; CYTOPLASM; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MASS SPECTROMETRY; MILD COGNITIVE IMPAIRMENT; MOUSE; NEURITE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN DOMAIN; SIGNAL TRANSDUCTION;

EID: 77951653609     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5874-09.2010     Document Type: Article

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