Oxidative stress induced by copper and iron complexes with 8-hydroxyquinoline derivatives causes paraptotic death of HeLa cancer cells

Molecular Pharmaceutics

Volumn 11, Issue 4, 2014, Pages 1151-1163

  Barilli, Amelia ^a   Atzeri, Corrado ^a   Bassanetti, Irene ^a   Ingoglia, Filippo ^a   Dall'Asta, Valeria ^a   Bussolati, Ovidio ^a   Maffini, Monica ^a   Mucchino, Claudio ^a   Marchiò, Luciano ^a  

^a UNIVERSITY OF PARMA   (Italy)

Author keywords

8 hydroxyquinoline; Copper; ionophore; iron; oxidative stress; paraptosis; unfolded protein response

Indexed keywords

8 QUINOLINOL DERIVATIVE; COBALT; COPPER COMPLEX; CUPRIC ION; FERRIC ION; IRON COMPLEX; LIGAND; NICKEL; QUINOLINIC ACID DERIVATIVE; CASPASE; COPPER; IRON; QUINOLINOL DERIVATIVE;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; HELA CELL; HUMAN; HUMAN CELL; IC 50; OXIDATIVE STRESS; PRIORITY JOURNAL; UNFOLDED PROTEIN RESPONSE; APOPTOSIS; CELL SURVIVAL; CHEMICAL STRUCTURE; DRUG EFFECTS; HELA CELL LINE; PHYSIOLOGY; SYNTHESIS;

APOPTOSIS; CASPASES; CELL SURVIVAL; COPPER; HELA CELLS; HUMANS; HYDROXYQUINOLINES; IRON; MOLECULAR STRUCTURE; OXIDATIVE STRESS; UNFOLDED PROTEIN RESPONSE;

EID: 84898007003     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp400592n     Document Type: Article

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