메뉴 건너뛰기




Volumn 29, Issue 5, 2014, Pages 534-544

Prenatal di-n-butyl phthalate exposure alters reproductive functions at adulthood in male rats

Author keywords

Di n butyl phthalate; Rat; Reproductive performance; Sperm; Testosterone

Indexed keywords

ENZYME ACTIVITY; ESTERS; RATING;

EID: 84897957575     PISSN: 15204081     EISSN: 15227278     Source Type: Journal    
DOI: 10.1002/tox.21779     Document Type: Article
Times cited : (35)

References (67)
  • 2
    • 77954525366 scopus 로고    scopus 로고
    • Prenatal plus postnatal exposure to di(n-butyl) phthalate and/or flutamide markedly reduces final Sertoli cell number in the rat
    • Auharek SA, de Franca LR, McKinnell C, Jobling MS, Scott HM, Sharpe RM. 2010. Prenatal plus postnatal exposure to di(n-butyl) phthalate and/or flutamide markedly reduces final Sertoli cell number in the rat. Endocrinology 151:2868-2875.
    • (2010) Endocrinology , vol.151 , pp. 2868-2875
    • Auharek, S.A.1    de Franca, L.R.2    McKinnell, C.3    Jobling, M.S.4    Scott, H.M.5    Sharpe, R.M.6
  • 3
    • 0037497143 scopus 로고    scopus 로고
    • Quantitative changes in gene expression in fetal rat testes following exposure to di(n-butyl) phthalate
    • Barlow NJ, Phillips SL, Wallace DG, Sar M, Gaido KW, Foster PM. 2003. Quantitative changes in gene expression in fetal rat testes following exposure to di(n-butyl) phthalate. Toxicol Sci 73:431-434.
    • (2003) Toxicol Sci , vol.73 , pp. 431-434
    • Barlow, N.J.1    Phillips, S.L.2    Wallace, D.G.3    Sar, M.4    Gaido, K.W.5    Foster, P.M.6
  • 4
    • 0030961755 scopus 로고    scopus 로고
    • A meta-analysis of 61 sperm count studies revisited
    • Becker S, Berhane K. 1997. A meta-analysis of 61 sperm count studies revisited. Fertil Steril 67:1103-1108.
    • (1997) Fertil Steril , vol.67 , pp. 1103-1108
    • Becker, S.1    Berhane, K.2
  • 6
    • 0001018483 scopus 로고
    • β-hydroxysteroid dehydrogenase. In: Bergmayer HU,editor. New York:Academic Press.
    • Bergmayer HU. 1974. β-hydroxysteroid dehydrogenase. In: Bergmayer HU, editor. Methods of Enzymatic Analysis. New York:Academic Press. pp 447-489.
    • (1974) Methods of Enzymatic Analysis , pp. 447-489
    • Bergmayer, H.U.1
  • 8
    • 0027428381 scopus 로고
    • Developmental effects of endocrine-disrupting chemicals in wildlife and humans
    • Colborn T, Vom Saal FS, Soto AM. 1993. Developmental effects of endocrine-disrupting chemicals in wildlife and humans. Environ Health Perspect 101:378-384.
    • (1993) Environ Health Perspect , vol.101 , pp. 378-384
    • Colborn, T.1    Vom Saal, F.S.2    Soto, A.M.3
  • 9
    • 12344284935 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors: Mediators of phthalate ester-induced effects in the male reproductive tract?
    • Corton JC, Lapinskas PJ. 2005. Peroxisome proliferator-activated receptors: Mediators of phthalate ester-induced effects in the male reproductive tract?Toxicol Sci 83:4-17.
    • (2005) Toxicol Sci , vol.83 , pp. 4-17
    • Corton, J.C.1    Lapinskas, P.J.2
  • 10
    • 0041523906 scopus 로고    scopus 로고
    • CPCSEA guidelines for laboratory animal facility
    • CPCSEA (Committee for the Purpose of Control and Supervision on Experiments on Animals).
    • CPCSEA (Committee for the Purpose of Control and Supervision on Experiments on Animals). 2003. CPCSEA guidelines for laboratory animal facility. Indian J Pharmacol 35:257-274.
    • (2003) Indian J Pharmacol , vol.35 , pp. 257-274
  • 11
    • 33646787797 scopus 로고    scopus 로고
    • Proposed mode of action for in utero effects of some phthalate esters on the developing male reproductive tract
    • David RM. 2006. Proposed mode of action for in utero effects of some phthalate esters on the developing male reproductive tract. Toxicol Pathol 34:209-219.
    • (2006) Toxicol Pathol , vol.34 , pp. 209-219
    • David, R.M.1
  • 12
    • 84907132954 scopus 로고
    • A note on the staining of the skeleton of cleared specimens with alizarin red S
    • Dawson AB. 1926. A note on the staining of the skeleton of cleared specimens with alizarin red S. Stain Technol 1:123-125.
    • (1926) Stain Technol , vol.1 , pp. 123-125
    • Dawson, A.B.1
  • 13
    • 1242275292 scopus 로고    scopus 로고
    • The relationship between environmental exposure to phthalates and computer-aided sperm analysis motion parameters
    • Duty SM, Calafat AM, Silva MJ, Brock JW, Ryan L, Chen Z, Overstreet J, Hauser R. 2004. The relationship between environmental exposure to phthalates and computer-aided sperm analysis motion parameters. J Androl 25:293-302.
    • (2004) J Androl , vol.25 , pp. 293-302
    • Duty, S.M.1    Calafat, A.M.2    Silva, M.J.3    Brock, J.W.4    Ryan, L.5    Chen, Z.6    Overstreet, J.7    Hauser, R.8
  • 14
    • 0027284557 scopus 로고
    • Teratogenic evaluation of di-n-butyl phthalate in rats
    • Ema M, Amano H, Itami T, Kawasaki H. 1993. Teratogenic evaluation of di-n-butyl phthalate in rats. Toxicol Lett 69:197-203.
    • (1993) Toxicol Lett , vol.69 , pp. 197-203
    • Ema, M.1    Amano, H.2    Itami, T.3    Kawasaki, H.4
  • 15
    • 0028174620 scopus 로고
    • Characterization of the developmental toxicity of di-n-butyl phthalate in rats
    • Ema M, Amano H, Ogawa Y. 1994. Characterization of the developmental toxicity of di-n-butyl phthalate in rats. Toxicology 86:163-174.
    • (1994) Toxicology , vol.86 , pp. 163-174
    • Ema, M.1    Amano, H.2    Ogawa, Y.3
  • 16
    • 0033989741 scopus 로고    scopus 로고
    • Critical period for adverse effects on development of reproductive system in male offspring of rats given di-n-butyl phthalate during late pregnancy
    • Ema M, Miyawaki E, Kawashima K. 2000a. Critical period for adverse effects on development of reproductive system in male offspring of rats given di-n-butyl phthalate during late pregnancy. Toxicol Lett 111:271-278.
    • (2000) Toxicol Lett , vol.111 , pp. 271-278
    • Ema, M.1    Miyawaki, E.2    Kawashima, K.3
  • 17
    • 0034057370 scopus 로고    scopus 로고
    • Effects of di-n-butyl phthalate on reproductive function in pregnant and pseudopregnant rats
    • Ema M, Miyawaki E, Kawashima K. 2000b. Effects of di-n-butyl phthalate on reproductive function in pregnant and pseudopregnant rats. Reprod Toxicol 14:13-19.
    • (2000) Reprod Toxicol , vol.14 , pp. 13-19
    • Ema, M.1    Miyawaki, E.2    Kawashima, K.3
  • 18
    • 1842434975 scopus 로고    scopus 로고
    • Environmental anti-androgens and male reproductive health: Focus on phthalates and testicular dysgenesis syndrome
    • Fisher JS. 2004. Environmental anti-androgens and male reproductive health: Focus on phthalates and testicular dysgenesis syndrome. Reproduction 127:305-315.
    • (2004) Reproduction , vol.127 , pp. 305-315
    • Fisher, J.S.1
  • 19
    • 0035676835 scopus 로고    scopus 로고
    • Function of seminal vesicles and their role on male fertility
    • Gonzales GF. 2001. Function of seminal vesicles and their role on male fertility. Asian J Androl 3:251-258.
    • (2001) Asian J Androl , vol.3 , pp. 251-258
    • Gonzales, G.F.1
  • 20
    • 0019225346 scopus 로고
    • Homosexual behavior in prenatally stressed male rats after castration and oestrogen treatment in adulthood
    • Gotz G, Dorner G. 1980. Homosexual behavior in prenatally stressed male rats after castration and oestrogen treatment in adulthood. Endokrinologie 76:115-117.
    • (1980) Endokrinologie , vol.76 , pp. 115-117
    • Gotz, G.1    Dorner, G.2
  • 21
    • 0343090362 scopus 로고    scopus 로고
    • Administration of potentially antiandrogenic pesticides (procymidone, linuron, iprodione, chlozolinate, p,p'-DDE, and ketoconazole) and toxic substances (dibutyl- and diethylhexyl phthalate, PCB 169, and ethane dimethane sulphonate) during sexual differentiation produces diverse profiles of reproductive malformations in the male rat
    • Gray LEJr, Wolf C, Lambright C, Mann P, Price M, Cooper RL, Ostby J. 1999. Administration of potentially antiandrogenic pesticides (procymidone, linuron, iprodione, chlozolinate, p, p'-DDE, and ketoconazole) and toxic substances (dibutyl- and diethylhexyl phthalate, PCB 169, and ethane dimethane sulphonate) during sexual differentiation produces diverse profiles of reproductive malformations in the male rat. Toxicol Ind Health 15:94-118.
    • (1999) Toxicol Ind Health , vol.15 , pp. 94-118
    • Gray, L.E.1    Wolf, C.2    Lambright, C.3    Mann, P.4    Price, M.5    Cooper, R.L.6    Ostby, J.7
  • 22
    • 0034523473 scopus 로고    scopus 로고
    • Prenatal exposure to the phthalate DEHP,BBP, and DINP, but not DEP, DMP, or DOTP, alters sexual differentiation of the male rat
    • Gray LEJr, Ostby J, Furr J, Price M, Veeramachaneni DN, Parks L. 2000. Prenatal exposure to the phthalate DEHP, BBP, and DINP, but not DEP, DMP, or DOTP, alters sexual differentiation of the male rat. Toxicol Sci 58:350-365.
    • (2000) Toxicol Sci , vol.58 , pp. 350-365
    • Gray, L.E.1    Ostby, J.2    Furr, J.3    Price, M.4    Veeramachaneni, D.N.5    Parks, L.6
  • 24
    • 77956127888 scopus 로고
    • 125I labeled human growth hormone of high specific radioactivity
    • 125I labeled human growth hormone of high specific radioactivity. Biochem J 89:114-123.
    • (1963) Biochem J , vol.89 , pp. 114-123
    • Greenwood, F.C.1    Hunter, W.M.2    Clover, J.S.3
  • 25
    • 33750482232 scopus 로고    scopus 로고
    • Altered semen quality in relation to urinary concentrations of phthalate monoester and oxidative metabolites
    • Hauser R, Meeker JD, Duty S, Silva MJ, Calafat AM. 2006. Altered semen quality in relation to urinary concentrations of phthalate monoester and oxidative metabolites. Epidemiology 17:682-691.
    • (2006) Epidemiology , vol.17 , pp. 682-691
    • Hauser, R.1    Meeker, J.D.2    Duty, S.3    Silva, M.J.4    Calafat, A.M.5
  • 26
    • 34247892413 scopus 로고    scopus 로고
    • DNA damage in human sperm is related to urinary levels of phthalate monoester and oxidative metabolites
    • Hauser R, Meeker JD, Singh NP, Silva MJ, Duty S, Ryan L, Calafat AM. 2007. DNA damage in human sperm is related to urinary levels of phthalate monoester and oxidative metabolites. Hum Reprod 22:688-695.
    • (2007) Hum Reprod , vol.22 , pp. 688-695
    • Hauser, R.1    Meeker, J.D.2    Singh, N.P.3    Silva, M.J.4    Duty, S.5    Ryan, L.6    Calafat, A.M.7
  • 29
    • 51849108613 scopus 로고    scopus 로고
    • The oral rat with inherited cryptorchidism has increased susceptibility to the testicular effects of in utero dibutyl phthalate exposure
    • Johnson KJ, McCahan SM, Si X, Campion L, Herrmann R, Barthold JS. 2008. The oral rat with inherited cryptorchidism has increased susceptibility to the testicular effects of in utero dibutyl phthalate exposure. Toxicol Sci 105:360-367.
    • (2008) Toxicol Sci , vol.105 , pp. 360-367
    • Johnson, K.J.1    McCahan, S.M.2    Si, X.3    Campion, L.4    Herrmann, R.5    Barthold, J.S.6
  • 30
    • 20544448920 scopus 로고    scopus 로고
    • Urinary phthalate metabolites and biomarkers of reproductive function in young men
    • Jönsson BA, Richthoff J, Rylander L, Giwercman A, Hagmar L. 2005. Urinary phthalate metabolites and biomarkers of reproductive function in young men. Epidemiology 16:487-493.
    • (2005) Epidemiology , vol.16 , pp. 487-493
    • Jönsson, B.A.1    Richthoff, J.2    Rylander, L.3    Giwercman, A.4    Hagmar, L.5
  • 31
    • 13844272467 scopus 로고    scopus 로고
    • Long-term effects of intrauterine exposure to mono-n-butyl phthalate on the reproductive function of postnatal rats
    • Kai H, Shono T, Tajiri T, Suita S. 2005. Long-term effects of intrauterine exposure to mono-n-butyl phthalate on the reproductive function of postnatal rats. J Pediatr Surg 40:429-433.
    • (2005) J Pediatr Surg , vol.40 , pp. 429-433
    • Kai, H.1    Shono, T.2    Tajiri, T.3    Suita, S.4
  • 32
    • 0032889677 scopus 로고    scopus 로고
    • Redox regulation of cellular signalling
    • Kamata H, Hirata H. 1999. Redox regulation of cellular signalling. Cell Signal 11:1-14.
    • (1999) Cell Signal , vol.11 , pp. 1-14
    • Kamata, H.1    Hirata, H.2
  • 34
    • 23844539020 scopus 로고    scopus 로고
    • Exposure in utero to di (n-butyl) phthalate alters the vimentin cytoskeleton of fetal rat Sertoli cells and disrupts Sertoli cell-gonocyte contact
    • Kleymenova E, Swanson C, Boekelheide K, Guido KW. 2005. Exposure in utero to di (n-butyl) phthalate alters the vimentin cytoskeleton of fetal rat Sertoli cells and disrupts Sertoli cell-gonocyte contact. Biol Reprod 73:482-490.
    • (2005) Biol Reprod , vol.73 , pp. 482-490
    • Kleymenova, E.1    Swanson, C.2    Boekelheide, K.3    Guido, K.W.4
  • 35
    • 0002705688 scopus 로고    scopus 로고
    • Toxicity of the excurrent ducts and accessory organs in the male
    • Korach KS,editor. New York:Marcel Dekker.
    • Klinefelter GR, Hess RA. 1998. Toxicity of the excurrent ducts and accessory organs in the male. In: Korach KS, editor. Reproductive and Developmental Toxicology. New York:Marcel Dekker. pp 553-591.
    • (1998) Reproductive and Developmental Toxicology , pp. 553-591
    • Klinefelter, G.R.1    Hess, R.A.2
  • 36
    • 0037416713 scopus 로고    scopus 로고
    • Changes in peroxisome proliferator-activated receptor gamma-regulated gene expression and inhibin/activin-follistatin system gene expression in rat testis after an administration of di-n-butyl phthalate
    • Kobayashi T, Niimi S, Kawanishi T, Fukuoka M, Hayakawa T. 2003. Changes in peroxisome proliferator-activated receptor gamma-regulated gene expression and inhibin/activin-follistatin system gene expression in rat testis after an administration of di-n-butyl phthalate. Toxicol Lett 138:215-225.
    • (2003) Toxicol Lett , vol.138 , pp. 215-225
    • Kobayashi, T.1    Niimi, S.2    Kawanishi, T.3    Fukuoka, M.4    Hayakawa, T.5
  • 37
    • 33645231471 scopus 로고    scopus 로고
    • Di(2-ethylhexyl)phthalate (DEHP): Human metabolism and internal exposure-An update and latest results
    • Koch HM, Preuss R, Angerer J. 2006. Di(2-ethylhexyl)phthalate (DEHP): Human metabolism and internal exposure-An update and latest results. Int J Androl 29:155-165.
    • (2006) Int J Androl , vol.29 , pp. 155-165
    • Koch, H.M.1    Preuss, R.2    Angerer, J.3
  • 38
    • 4444242509 scopus 로고    scopus 로고
    • Dose-dependent alterations in gene expression and testosterone synthesis in the fetal testes of male rats exposed to di (n-butyl) phthalate
    • Lehmann KP, Phillips S, Sar M, Foster PMD, Gaido KW. 2004. Dose-dependent alterations in gene expression and testosterone synthesis in the fetal testes of male rats exposed to di (n-butyl) phthalate. Toxicol Sci 8:60-68.
    • (2004) Toxicol Sci , vol.8 , pp. 60-68
    • Lehmann, K.P.1    Phillips, S.2    Sar, M.3    Foster, P.M.D.4    Gaido, K.W.5
  • 39
    • 0023712119 scopus 로고
    • Inhibition of ovulation, steroidogenesis and collagenolytic activity in rabbits by sulphide induced hyperprolactinemia
    • Lin KC, Kawamura N, Okumura H, Mori T. 1988. Inhibition of ovulation, steroidogenesis and collagenolytic activity in rabbits by sulphide induced hyperprolactinemia. J Reprod Fertil 83:611-618.
    • (1988) J Reprod Fertil , vol.83 , pp. 611-618
    • Lin, K.C.1    Kawamura, N.2    Okumura, H.3    Mori, T.4
  • 40
    • 0027032045 scopus 로고
    • Endpoints of spermatotoxicity in rats after short duration exposures to fourteen reproductive toxicants
    • Linder RE, Strader LF, Slott VL, Suarez JD. 1992. Endpoints of spermatotoxicity in rats after short duration exposures to fourteen reproductive toxicants. Reprod Toxicol 6:491-505.
    • (1992) Reprod Toxicol , vol.6 , pp. 491-505
    • Linder, R.E.1    Strader, L.F.2    Slott, V.L.3    Suarez, J.D.4
  • 41
    • 20844441799 scopus 로고    scopus 로고
    • Gene expression profiling following in utero exposure to phthalate esters reveals new gene targets in the etiology of testicular dysgenesis
    • Liu K, Lehmann KP, Sar M, Young SS, Gaido KW. 2005. Gene expression profiling following in utero exposure to phthalate esters reveals new gene targets in the etiology of testicular dysgenesis. Biol Reprod 73:180-192.
    • (2005) Biol Reprod , vol.73 , pp. 180-192
    • Liu, K.1    Lehmann, K.P.2    Sar, M.3    Young, S.S.4    Gaido, K.W.5
  • 46
    • 40949139384 scopus 로고    scopus 로고
    • In utero exposure to di(n-butyl) phthalate and testicular dysgenesis: Comparison of fetal and adult end points and their dose sensitivity
    • Mahood IK, Scott HM, Brown R, Hallmark N, Walker M, Sharpe RM. 2007. In utero exposure to di(n-butyl) phthalate and testicular dysgenesis: Comparison of fetal and adult end points and their dose sensitivity. Environ Health Perspect 115:55-61.
    • (2007) Environ Health Perspect , vol.115 , pp. 55-61
    • Mahood, I.K.1    Scott, H.M.2    Brown, R.3    Hallmark, N.4    Walker, M.5    Sharpe, R.M.6
  • 48
    • 0016040598 scopus 로고
    • Secretary function of the prostate, seminal vesicle and other male accessory organs of reproduction
    • Mann T. 1974. Secretary function of the prostate, seminal vesicle and other male accessory organs of reproduction. J Reprod Fertil 37:179-188.
    • (1974) J Reprod Fertil , vol.37 , pp. 179-188
    • Mann, T.1
  • 49
    • 37349099580 scopus 로고    scopus 로고
    • Potential adverse effects of phthalic acid esters on human health: A review of recent studies on reproduction
    • Matsumoto M, Hirata-Koizumi M, Ema M. 2008. Potential adverse effects of phthalic acid esters on human health: A review of recent studies on reproduction. Regul Toxicol Pharmacol 50:37-49.
    • (2008) Regul Toxicol Pharmacol , vol.50 , pp. 37-49
    • Matsumoto, M.1    Hirata-Koizumi, M.2    Ema, M.3
  • 50
    • 67650813037 scopus 로고    scopus 로고
    • Phthalates and other additives in plastics: Human exposure and associated health outcomes
    • Meeker JD, Sathyanarayana S, Swan SH. 2009. Phthalates and other additives in plastics: Human exposure and associated health outcomes. Philos Trans R Soc Lond B Biol Sci 364:2097-2113.
    • (2009) Philos Trans R Soc Lond B Biol Sci , vol.364 , pp. 2097-2113
    • Meeker, J.D.1    Sathyanarayana, S.2    Swan, S.H.3
  • 51
    • 34250358170 scopus 로고    scopus 로고
    • Transplacental transfer of monomethyl phthalate and mono (2-ethylhexyl) phthalate in a human placenta perfusion system
    • Mose T, Knudsen LE, Hedegaard M, Mortensen GK, Hedegaard M, Knudsen LE. 2007. Transplacental transfer of monomethyl phthalate and mono (2-ethylhexyl) phthalate in a human placenta perfusion system. Int J Toxicol 26:221-229.
    • (2007) Int J Toxicol , vol.26 , pp. 221-229
    • Mose, T.1    Knudsen, L.E.2    Hedegaard, M.3    Mortensen, G.K.4    Hedegaard, M.5    Knudsen, L.E.6
  • 52
    • 0031860360 scopus 로고    scopus 로고
    • Male reproductive tract malformations in rats following gestational and lactational exposure to di(n-butyl) phthalate: An antiandrogenic mechanism?
    • Mylchreest E, Cattley RC, Foster PMD. 1998. Male reproductive tract malformations in rats following gestational and lactational exposure to di(n-butyl) phthalate: An antiandrogenic mechanism?Toxicol Sci 43:47-60.
    • (1998) Toxicol Sci , vol.43 , pp. 47-60
    • Mylchreest, E.1    Cattley, R.C.2    Foster, P.M.D.3
  • 53
    • 0033010382 scopus 로고    scopus 로고
    • Disruption of androgen-regulated male reproductive development by di(n-butyl) phthalate during late gestation in rats is different from flutamide
    • Mylchreest E, Sar M, Cattley RC, Foster PM. 1999. Disruption of androgen-regulated male reproductive development by di(n-butyl) phthalate during late gestation in rats is different from flutamide. Toxicol Appl Pharmacol 156:81-95.
    • (1999) Toxicol Appl Pharmacol , vol.156 , pp. 81-95
    • Mylchreest, E.1    Sar, M.2    Cattley, R.C.3    Foster, P.M.4
  • 54
    • 0034021024 scopus 로고    scopus 로고
    • Dose-dependent alterations in androgen-regulated male reproductive development in rats exposed to di(n-butyl) phthalate during late gestation
    • Mylchreest E, Wallace DG, Cattley RC, Foster PM. 2000. Dose-dependent alterations in androgen-regulated male reproductive development in rats exposed to di(n-butyl) phthalate during late gestation. Toxicol Sci 55:143-151.
    • (2000) Toxicol Sci , vol.55 , pp. 143-151
    • Mylchreest, E.1    Wallace, D.G.2    Cattley, R.C.3    Foster, P.M.4
  • 55
    • 0036010069 scopus 로고    scopus 로고
    • Fetal testosterone insufficiency and abnormal proliferation of Leydig cells and gonocytes in rats exposed to di(n-butyl) phthalate
    • Mylchreest E, Sar M, Wallace DG, Foster PM. 2002. Fetal testosterone insufficiency and abnormal proliferation of Leydig cells and gonocytes in rats exposed to di(n-butyl) phthalate. Reprod Toxicol 16:19-28.
    • (2002) Reprod Toxicol , vol.16 , pp. 19-28
    • Mylchreest, E.1    Sar, M.2    Wallace, D.G.3    Foster, P.M.4
  • 56
    • 54549106722 scopus 로고    scopus 로고
    • Effect on histological and sperm kinetics in DBP exposed Wistar rats
    • Nair N, Bedwal S, Kumari D, Bedwal S, Bedwal RS. 2008. Effect on histological and sperm kinetics in DBP exposed Wistar rats. J Environ Biol 29:769-772.
    • (2008) J Environ Biol , vol.29 , pp. 769-772
    • Nair, N.1    Bedwal, S.2    Kumari, D.3    Bedwal, S.4    Bedwal, R.S.5
  • 58
    • 0034521058 scopus 로고    scopus 로고
    • The plasticizer diethylhexyl phthalate induces malformations by decreasing fetal testosterone synthesis during sexual differentiation in the male rat
    • Parks LG, Ostby JS, Lambright CR, Abbott BD, Klinefelter GR, Barlow NJ, Gray LE. 2000. The plasticizer diethylhexyl phthalate induces malformations by decreasing fetal testosterone synthesis during sexual differentiation in the male rat. Toxicol Sci 58:339-349.
    • (2000) Toxicol Sci , vol.58 , pp. 339-349
    • Parks, L.G.1    Ostby, J.S.2    Lambright, C.R.3    Abbott, B.D.4    Klinefelter, G.R.5    Barlow, N.J.6    Gray, L.E.7
  • 59
    • 0025670608 scopus 로고
    • Effect of constant infusion of gonadotropin releasing hormone (GnRH) agonist buserelin and antagonist CDB 2085 A using osmotic mini pumps on testicular function in adult male bonnet monkey (Macaca radiata)
    • Rao AJ, Chakraborti R, Kotagi SG, Ravindranath N. 1990. Effect of constant infusion of gonadotropin releasing hormone (GnRH) agonist buserelin and antagonist CDB 2085 A using osmotic mini pumps on testicular function in adult male bonnet monkey (Macaca radiata). Andrologia 22:567-573.
    • (1990) Andrologia , vol.22 , pp. 567-573
    • Rao, A.J.1    Chakraborti, R.2    Kotagi, S.G.3    Ravindranath, N.4
  • 60
    • 77955286617 scopus 로고    scopus 로고
    • Functional and morphological reproductive aspects in male rats exposed to di-n-butyl phthalate (DBP) in utero and during lactation
    • Scarano WR, Toledo FC, Guerra MT, Pinheiro PF, Domeniconi RF. 2010. Functional and morphological reproductive aspects in male rats exposed to di-n-butyl phthalate (DBP) in utero and during lactation. J Toxicol Environ Health A 73:972-984.
    • (2010) J Toxicol Environ Health A , vol.73 , pp. 972-984
    • Scarano, W.R.1    Toledo, F.C.2    Guerra, M.T.3    Pinheiro, P.F.4    Domeniconi, R.F.5
  • 62
    • 0019526424 scopus 로고
    • A triple stain technique for evaluating normal acrosome reaction of human sperm
    • Talbot P, Chacon RS. 1981. A triple stain technique for evaluating normal acrosome reaction of human sperm. J Exp Zool 215:201-208.
    • (1981) J Exp Zool , vol.215 , pp. 201-208
    • Talbot, P.1    Chacon, R.S.2
  • 64
    • 0015496412 scopus 로고
    • Prenatal stress feminizes and demasculinizes the behavior of males
    • Ward I. 1972. Prenatal stress feminizes and demasculinizes the behavior of males. Science 175:82-84.
    • (1972) Science , vol.175 , pp. 82-84
    • Ward, I.1
  • 65
    • 0030953834 scopus 로고    scopus 로고
    • Reproductive toxicity of di-n-butyl phthalate in a continuous breeding protocol in Sprague-Dawley rats
    • Wine RN, Li LH, Barnes LH, Gulati DK, Chapin RE. 1997. Reproductive toxicity of di-n-butyl phthalate in a continuous breeding protocol in Sprague-Dawley rats. Environ Health Perspect 105:102-107.
    • (1997) Environ Health Perspect , vol.105 , pp. 102-107
    • Wine, R.N.1    Li, L.H.2    Barnes, L.H.3    Gulati, D.K.4    Chapin, R.E.5
  • 66
    • 3042577511 scopus 로고    scopus 로고
    • Reproductive and developmental toxicity of F1 Sprague Dawley male rats exposed to di-n-butyl phthalate in utero and during lactation and determination of its NOEL
    • Zhang Y, Jiang X, Chen B. 2004. Reproductive and developmental toxicity of F1 Sprague Dawley male rats exposed to di-n-butyl phthalate in utero and during lactation and determination of its NOEL. Reprod Toxicol 18:669-676.
    • (2004) Reprod Toxicol , vol.18 , pp. 669-676
    • Zhang, Y.1    Jiang, X.2    Chen, B.3
  • 67
    • 33747291386 scopus 로고    scopus 로고
    • Phthalate exposure and human semen quality in Shanghai: A cross-sectional study
    • Zhang YH, Zheng LX, Chen BH. 2006. Phthalate exposure and human semen quality in Shanghai: A cross-sectional study. Biomed Environ Sci 19:205-209.
    • (2006) Biomed Environ Sci , vol.19 , pp. 205-209
    • Zhang, Y.H.1    Zheng, L.X.2    Chen, B.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.