메뉴 건너뛰기




Volumn 5 MAR, Issue , 2014, Pages

CaMKII in sinoatrial node physiology and dysfunction

Author keywords

Calcium; Calcium calmodulin dependent protein kinase II; Heart rate; Sinoatrial node; Sinoatrial node dysfunction

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CYCLIC AMP DEPENDENT PROTEIN KINASE; METHIONINE SULFOXIDE REDUCTASE A; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE;

EID: 84897952396     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2014.00048     Document Type: Review
Times cited : (45)

References (58)
  • 2
    • 77958074655 scopus 로고    scopus 로고
    • Expression and distribution of voltage-gated ion channels in ferret sinoatrial node
    • doi: 10.1152/physiolgenomics.00049.2010.
    • Brahmajothi, M. V., Morales, M. J., Campbell, D. L., Steenbergen, C., and Strauss, H. C. (2010). Expression and distribution of voltage-gated ion channels in ferret sinoatrial node. Physiol. Genomics. 42A, 131-40. doi: 10.1152/physiolgenomics.00049.2010.
    • (2010) Physiol. Genomics. , vol.42 A , pp. 131-140
    • Brahmajothi, M.V.1    Morales, M.J.2    Campbell, D.L.3    Steenbergen, C.4    Strauss, H.C.5
  • 4
    • 0035800882 scopus 로고    scopus 로고
    • Oxidative stress-mediated cardiac cell death is a major determinant of ventricular dysfunction and failure in dog dilated cardiomyopathy
    • doi: 10.1161/hh1501.094115
    • Cesselli, D., Jakoniuk, I., Barlucchi, L., Beltrami, A. P., Hintze, T. H., Nadal-Ginard, B., et al. (2001). Oxidative stress-mediated cardiac cell death is a major determinant of ventricular dysfunction and failure in dog dilated cardiomyopathy. Circ. Res. 89, 279-286. doi: 10.1161/hh1501.094115.
    • (2001) Circ. Res. , vol.89 , pp. 279-286
    • Cesselli, D.1    Jakoniuk, I.2    Barlucchi, L.3    Beltrami, A.P.4    Hintze, T.H.5    Nadal-Ginard, B.6
  • 5
    • 64749110218 scopus 로고    scopus 로고
    • Molecular architecture of the human sinus node: insights into the function of the cardiac pacemaker
    • doi: 0.1161/CIRCULATIONAHA.108.804369
    • Chandler, N. J., Greener, I. D., Tellez, J. O., Inada, S., Musa, H., Molenaar, P., et al. (2009). Molecular architecture of the human sinus node: insights into the function of the cardiac pacemaker. Circulation 119, 1562-1575. doi: 0.1161/CIRCULATIONAHA.108.804369.
    • (2009) Circulation , vol.119 , pp. 1562-1575
    • Chandler, N.J.1    Greener, I.D.2    Tellez, J.O.3    Inada, S.4    Musa, H.5    Molenaar, P.6
  • 6
    • 0032168992 scopus 로고    scopus 로고
    • Characterization of a calmodulin kinase II inhibitor protein in brain
    • doi: 10.1073/pnas.95.18.10890
    • Chang, B. H., Mukherji, S., and Soderling, T. R. (1998). Characterization of a calmodulin kinase II inhibitor protein in brain. Proc. Natl. Acad. Sci. U.S.A. 95, 10890-10895. doi: 10.1073/pnas.95.18.10890.
    • (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , pp. 10890-10895
    • Chang, B.H.1    Mukherji, S.2    Soderling, T.R.3
  • 7
    • 84879699727 scopus 로고    scopus 로고
    • Sinus node dysfunction in atrial fibrillation patients: the evidence of regional atrial substrate remodelling
    • doi: 10.1093/europace/eus219
    • Chang, H. Y., Lin, Y. J., Lo, L. W., Chang, S. L., Hu, Y. F., Li, C. H., et al. (2013). Sinus node dysfunction in atrial fibrillation patients: the evidence of regional atrial substrate remodelling. Europace 15, 205-211. doi: 10.1093/europace/eus219.
    • (2013) Europace , vol.15 , pp. 205-211
    • Chang, H.Y.1    Lin, Y.J.2    Lo, L.W.3    Chang, S.L.4    Hu, Y.F.5    Li, C.H.6
  • 9
    • 26444549396 scopus 로고    scopus 로고
    • Calmodulin antagonist W7 directly inhibits f-type current in rabbit sino-atrial cells
    • doi: 10.1016/j.ejphar.2005.08.024
    • Chatelier, A., Renaudon, B., Bescond, J., El Chemaly, A., Demion, M., and Bois, P. (2005). Calmodulin antagonist W7 directly inhibits f-type current in rabbit sino-atrial cells. Eur. J. Pharmacol. 521, 29-33. doi: 10.1016/j.ejphar.2005.08.024.
    • (2005) Eur. J. Pharmacol. , vol.521 , pp. 29-33
    • Chatelier, A.1    Renaudon, B.2    Bescond, J.3    El Chemaly, A.4    Demion, M.5    Bois, P.6
  • 11
    • 84859721871 scopus 로고    scopus 로고
    • Ca(2+)-stimulated adenylyl cyclases regulate the L-type Ca(2+) current in guinea-pig atrial myocytes
    • doi: 10.1113/jphysiol.2011.227066
    • Collins, T. P., and Terrar, D. A. (2012). Ca(2+)-stimulated adenylyl cyclases regulate the L-type Ca(2+) current in guinea-pig atrial myocytes. J. Physiol. 590(Pt 8), 1881-1893. doi: 10.1113/jphysiol.2011.227066.
    • (2012) J. Physiol. , vol.590 , Issue.PART 8 , pp. 1881-1893
    • Collins, T.P.1    Terrar, D.A.2
  • 12
    • 67649204729 scopus 로고    scopus 로고
    • Overexpression of catalase targeted to mitochondria attenuates murine cardiac aging
    • doi: 10.1161/CIRCULATIONAHA.108.822403
    • Dai, D. F., Santana, L. F., Vermulst, M., Tomazela, D. M., Emond, M. J., MacCoss, M. J., et al. (2009). Overexpression of catalase targeted to mitochondria attenuates murine cardiac aging. Circulation 119, 2789-2797. doi: 10.1161/CIRCULATIONAHA.108.822403.
    • (2009) Circulation , vol.119 , pp. 2789-2797
    • Dai, D.F.1    Santana, L.F.2    Vermulst, M.3    Tomazela, D.M.4    Emond, M.J.5    MacCoss, M.J.6
  • 13
    • 0025977991 scopus 로고
    • The contribution of the "pacemaker" current (if) to generation of spontaneous activity in rabbit sino-atrial node myocytes
    • DiFrancesco, D. (1991). The contribution of the "pacemaker" current (if) to generation of spontaneous activity in rabbit sino-atrial node myocytes. J. Physiol. 434, 23-40.
    • (1991) J. Physiol. , vol.434 , pp. 23-40
    • DiFrancesco, D.1
  • 14
    • 0033781028 scopus 로고    scopus 로고
    • Calmodulin kinase determines calcium-dependent facilitation of L-type calcium channels
    • doi: 10.1038/35004052
    • Dzhura, I., Wu, Y., Colbran, R. J., Balser, J. R., and Anderson, M. E. (2000). Calmodulin kinase determines calcium-dependent facilitation of L-type calcium channels. Nat. Cell Biol. 2, 173-177. doi: 10.1038/35004052.
    • (2000) Nat. Cell Biol. , vol.2 , pp. 173-177
    • Dzhura, I.1    Wu, Y.2    Colbran, R.J.3    Balser, J.R.4    Anderson, M.E.5
  • 15
    • 79960108482 scopus 로고    scopus 로고
    • CaMKII in the cardiovascular system: sensing redox states
    • doi: 10.1152/physrev.00018.2010
    • Erickson, J. R., He, B. J., Grumbach, I. M., and Anderson, M. E. (2011). CaMKII in the cardiovascular system: sensing redox states. Physiol. Rev. 91, 889-915. doi: 10.1152/physrev.00018.2010.
    • (2011) Physiol. Rev. , vol.91 , pp. 889-915
    • Erickson, J.R.1    He, B.J.2    Grumbach, I.M.3    Anderson, M.E.4
  • 16
    • 42949085382 scopus 로고    scopus 로고
    • A dynamic pathway for calcium-independent activation of CaMKII by methionine oxidation
    • doi: 10.1016/j.cell.2008.02.048
    • Erickson, J. R., Joiner, M. L., Guan, X., Kutschke, W., Yang, J., Oddis, C. V., et al. (2008). A dynamic pathway for calcium-independent activation of CaMKII by methionine oxidation. Cell 133, 462-474. doi: 10.1016/j.cell.2008.02.048.
    • (2008) Cell , vol.133 , pp. 462-474
    • Erickson, J.R.1    Joiner, M.L.2    Guan, X.3    Kutschke, W.4    Yang, J.5    Oddis, C.V.6
  • 17
    • 84885863770 scopus 로고    scopus 로고
    • Diabetic hyperglycaemia activates CaMKII and arrhythmias by O-linked glycosylation
    • doi: 10.1038/nature12537
    • Erickson, J. R., Pereira, L., Wang, L., Han, G., Ferguson, A., Dao, K., et al. (2013). Diabetic hyperglycaemia activates CaMKII and arrhythmias by O-linked glycosylation. Nature 502, 372-376. doi: 10.1038/nature12537.
    • (2013) Nature , vol.502 , pp. 372-376
    • Erickson, J.R.1    Pereira, L.2    Wang, L.3    Han, G.4    Ferguson, A.5    Dao, K.6
  • 18
    • 33744541775 scopus 로고    scopus 로고
    • CaMKII-independent effects of KN93 and its inactive analog KN92: reversible inhibition of L-type calcium channels
    • doi: 10.1016/j.bbrc.2006.05.066
    • Gao, L., Blair, L. A., and Marshall, J. (2006). CaMKII-independent effects of KN93 and its inactive analog KN92: reversible inhibition of L-type calcium channels. Biochem. Biophys. Res. Commun. 345, 1606-1610. doi: 10.1016/j.bbrc.2006.05.066.
    • (2006) Biochem. Biophys. Res. Commun. , vol.345 , pp. 1606-1610
    • Gao, L.1    Blair, L.A.2    Marshall, J.3
  • 19
    • 33747881612 scopus 로고    scopus 로고
    • 2+ channel facilitation mediated by phosphorylation of the beta subunit by CaMKII
    • doi: 10.1016/j.molcel.2006.07.006
    • 2+ channel facilitation mediated by phosphorylation of the beta subunit by CaMKII. Mol. Cell 23, 641-650 doi: 10.1016/j.molcel.2006.07.006.
    • (2006) Mol. Cell , vol.23 , pp. 641-650
    • Grueter, C.E.1    Abiria, S.A.2    Dzhura, I.3    Wu, Y.4    Ham, A.J.5    Mohler, P.J.6
  • 20
    • 84887977874 scopus 로고    scopus 로고
    • NO-dependent CaMKII activation during β-adrenergic stimulation of cardiac muscle
    • doi: 10.1093/cvr/cvt201
    • Gutierrez, D. A., Fernandez-Tenorio, M., Ogrodnik, J., and Niggli, E. (2013). NO-dependent CaMKII activation during β-adrenergic stimulation of cardiac muscle. Cardiovasc. Res. 100, 392-401. doi: 10.1093/cvr/cvt201.
    • (2013) Cardiovasc. Res. , vol.100 , pp. 392-401
    • Gutierrez, D.A.1    Fernandez-Tenorio, M.2    Ogrodnik, J.3    Niggli, E.4
  • 21
    • 0024471765 scopus 로고
    • 2+ of the hyperpolarization-activated inward current in rabbit single sino-atrial node cells
    • 2+ of the hyperpolarization-activated inward current in rabbit single sino-atrial node cells. J. Physiol. 409, 121-141.
    • (1989) J. Physiol. , vol.409 , pp. 121-141
    • Hagiwara, N.1    Irisawa, H.2
  • 22
    • 34250011801 scopus 로고    scopus 로고
    • Effects of streptozotocin-induced diabetes on action potentials in the sinoatrial node compared with other regions of the rat heart
    • doi: 10.1007/s11010-006-9366-5
    • Howarth, F. C., Al-Sharhan, R., Al-Hammadi, A., and Qureshi, M. A. (2007). Effects of streptozotocin-induced diabetes on action potentials in the sinoatrial node compared with other regions of the rat heart. Mol. Cell Biochem. 300, 39-46. doi: 10.1007/s11010-006-9366-5.
    • (2007) Mol. Cell Biochem. , vol.300 , pp. 39-46
    • Howarth, F.C.1    Al-Sharhan, R.2    Al-Hammadi, A.3    Qureshi, M.A.4
  • 23
    • 0033795342 scopus 로고    scopus 로고
    • P47(phox)-deficient NADPH oxidase defect in neutrophils of diabetic mouse strains, C57BL/6J-m db/db and db/+
    • Huang, C. K., Zhan, L., Hannigan, M. O., Ai, Y., and Leto, T. L. (2000). P47(phox)-deficient NADPH oxidase defect in neutrophils of diabetic mouse strains, C57BL/6J-m db/db and db/+. J. Leukoc. Biol. 67, 210-215.
    • (2000) J. Leukoc. Biol. , vol.67 , pp. 210-215
    • Huang, C.K.1    Zhan, L.2    Hannigan, M.O.3    Ai, Y.4    Leto, T.L.5
  • 24
    • 79961006773 scopus 로고    scopus 로고
    • Oxidized CaMKII: a "heart stopper" for the sinus node?
    • doi: 10.1172/JCI58389
    • Huke, S., and Knollmann, B. C. (2011). Oxidized CaMKII: a "heart stopper" for the sinus node? J. Clin. Invest. 121, 2975-2977. doi: 10.1172/JCI58389.
    • (2011) J. Clin. Invest. , vol.121 , pp. 2975-2977
    • Huke, S.1    Knollmann, B.C.2
  • 25
    • 12844285608 scopus 로고    scopus 로고
    • Targeted modification of atrial electrophysiology by homogeneous transmural atrial gene transfer
    • doi: 10.1161/01.CIR.0000153338.47507.83
    • Kikuchi, K., McDonald, A. D., Sasano, T., and Donahue, J. K. (2005). Targeted modification of atrial electrophysiology by homogeneous transmural atrial gene transfer. Circulation 111, 264-270. doi: 10.1161/01.CIR.0000153338.47507.83.
    • (2005) Circulation , vol.111 , pp. 264-270
    • Kikuchi, K.1    McDonald, A.D.2    Sasano, T.3    Donahue, J.K.4
  • 26
    • 26244432775 scopus 로고    scopus 로고
    • A myocardial Nox2 containing NAD(P)H oxidase contributes to oxidative stress in human atrial fibrillation
    • doi: 10.1161/01.RES.0000183735.09871.61
    • Kim, Y. M., Guzik, T. J., Zhang, Y. H., Zhang, M. H., Kattach, H., Ratnatunga, C., et al. (2005). A myocardial Nox2 containing NAD(P)H oxidase contributes to oxidative stress in human atrial fibrillation. Circ. Res. 97, 629-636. doi: 10.1161/01.RES.0000183735.09871.61.
    • (2005) Circ. Res. , vol.97 , pp. 629-636
    • Kim, Y.M.1    Guzik, T.J.2    Zhang, Y.H.3    Zhang, M.H.4    Kattach, H.5    Ratnatunga, C.6
  • 27
    • 0023600751 scopus 로고
    • Calmodulin antagonists depress calcium and potassium currents in ventricular and vascular myocytes
    • Klöckner, U., and Isenberg, G. (1987). Calmodulin antagonists depress calcium and potassium currents in ventricular and vascular myocytes. Am. J. Physiol. 253(6 Pt 2), H1601-H1611.
    • (1987) Am. J. Physiol. , vol.253 , Issue.6 PART 2
    • Klöckner, U.1    Isenberg, G.2
  • 28
    • 84862286538 scopus 로고    scopus 로고
    • Modulation of cardiac contractility by the phospholamban/SERCA2a regulatome
    • doi: 10.1161/CIRCRESAHA.111.259754
    • Kranias, E. G., and Hajjar, R. J. (2012). Modulation of cardiac contractility by the phospholamban/SERCA2a regulatome. Circ. Res. 110, 1646-1660. doi: 10.1161/CIRCRESAHA.111.259754.
    • (2012) Circ. Res. , vol.110 , pp. 1646-1660
    • Kranias, E.G.1    Hajjar, R.J.2
  • 29
    • 0021807380 scopus 로고
    • 2+/calmodulin-dependent protein kinase
    • 2+/calmodulin-dependent protein kinase. J. Biol. Chem. 260, 6427-6433.
    • (1985) J. Biol. Chem. , vol.260 , pp. 6427-6433
    • Kuret, J.1    Schulman, H.2
  • 30
    • 67649104033 scopus 로고    scopus 로고
    • What keeps us ticking: a funny current, a calcium clock, or both?
    • doi: 10.1016/j.yjmcc.2009.03.022
    • Lakatta, E. G., and DiFrancesco, D. (2009). What keeps us ticking: a funny current, a calcium clock, or both? J. Mol. Cell Cardiol. 47, 157-170. doi: 10.1016/j.yjmcc.2009.03.022.
    • (2009) J. Mol. Cell Cardiol. , vol.47 , pp. 157-170
    • Lakatta, E.G.1    DiFrancesco, D.2
  • 31
    • 77949379471 scopus 로고    scopus 로고
    • 2+ clocks and surface membrane voltage clocks controls the timekeeping mechanism of the heart's pacemaker
    • doi: 10.1161/CIRCRESAHA.109.206078
    • 2+ clocks and surface membrane voltage clocks controls the timekeeping mechanism of the heart's pacemaker. Circ. Res. 106, 659-673. doi: 10.1161/CIRCRESAHA.109.206078.
    • (2010) Circ. Res. , vol.106 , pp. 659-673
    • Lakatta, E.G.1    Maltsev, V.A.2    Vinogradova, T.M.3
  • 33
    • 79952569281 scopus 로고    scopus 로고
    • Myristoylated peptides potentiate the funny current (I(f)) in sinoatrial myocytes
    • doi: 10.4161/chan.5.2.14195
    • Liao, Z., St Clair, J. R., Larson, E. D., and Proenza, C. (2011). Myristoylated peptides potentiate the funny current (I(f)) in sinoatrial myocytes. Channels (Austin) 5, 115-119. doi: 10.4161/chan.5.2.14195.
    • (2011) Channels (Austin) , vol.5 , pp. 115-119
    • Liao, Z.1    St Clair, J.R.2    Larson, E.D.3    Proenza, C.4
  • 35
    • 84874607556 scopus 로고    scopus 로고
    • Diabetes increases mortality after myocardial infarction by oxidizing CaMKII
    • doi: 10.1172/JCI65268
    • Luo, M., Guan, X., Luczak, E. D., Lang, D., Kutschke, W., Gao, Z., et al. (2013). Diabetes increases mortality after myocardial infarction by oxidizing CaMKII. J. Clin. Invest. 123, 1262-1274. doi: 10.1172/JCI65268.
    • (2013) J. Clin. Invest. , vol.123 , pp. 1262-1274
    • Luo, M.1    Guan, X.2    Luczak, E.D.3    Lang, D.4    Kutschke, W.5    Gao, Z.6
  • 36
    • 33745403607 scopus 로고    scopus 로고
    • Bradycardia and slowing of the atrioventricular conduction in mice lacking CaV3.1/alpha1G T-type calcium channels
    • doi: 10.1161/01.RES.0000225862.14314.49
    • Mangoni, M. E., Traboulsie, A., Leoni, A. L., Couette, B., Marger, L., Le Quang, K., et al. (2006). Bradycardia and slowing of the atrioventricular conduction in mice lacking CaV3.1/alpha1G T-type calcium channels. Circ. Res. 98, 1422-1430. doi: 10.1161/01.RES.0000225862.14314.49.
    • (2006) Circ. Res. , vol.98 , pp. 1422-1430
    • Mangoni, M.E.1    Traboulsie, A.2    Leoni, A.L.3    Couette, B.4    Marger, L.5    Le Quang, K.6
  • 37
    • 77949641112 scopus 로고    scopus 로고
    • 2+ levels in right atrial myocardium of patients with atrial fibrillation
    • doi: 10.1161/CIRCRESAHA.109.203836
    • 2+ levels in right atrial myocardium of patients with atrial fibrillation. Circ. Res. 106, 1134-1144. doi: 10.1161/CIRCRESAHA.109.203836.
    • (2010) Circ. Res. , vol.106 , pp. 1134-1144
    • Neef, S.1    Dybkova, N.2    Sossalla, S.3    Ort, K.R.4    Fluschnik, N.5    Neumann, K.6
  • 38
    • 0027008282 scopus 로고
    • The prevalence of diabetes mellitus and other risk factors of atherosclerosis in bradycardia requiring pacemaker treatment
    • Podlaha, R., and Falk, A. (1992). The prevalence of diabetes mellitus and other risk factors of atherosclerosis in bradycardia requiring pacemaker treatment. Horm. Metab. Res. Suppl. 26, 84-87.
    • (1992) Horm. Metab. Res. Suppl. , vol.26 , pp. 84-87
    • Podlaha, R.1    Falk, A.2
  • 39
    • 84885795044 scopus 로고    scopus 로고
    • Oxidized Ca(2+)/calmodulin-dependent protein kinase II triggers atrial fibrillation
    • doi: 10.1161/CIRCULATIONAHA.113.003313
    • Purohit, A., Rokita, A. G., Guan, X., Chen, B., Koval, O. M., Voigt, N., et al. (2013). Oxidized Ca(2+)/calmodulin-dependent protein kinase II triggers atrial fibrillation. Circulation 128, 1748-1757. doi: 10.1161/CIRCULATIONAHA.113.003313.
    • (2013) Circulation , vol.128 , pp. 1748-1757
    • Purohit, A.1    Rokita, A.G.2    Guan, X.3    Chen, B.4    Koval, O.M.5    Voigt, N.6
  • 40
    • 33645120204 scopus 로고    scopus 로고
    • KN-93 (2-[N-(2-hydroxyethyl)]-N-(4-methoxybenzenesulfonyl)]amino-N-(4-chlorocinnamyl)-N-methylbenzylamine), a calcium/calmodulin-dependent protein kinase II inhibitor, is a direct extracellular blocker of voltage-gated potassium channels
    • doi: 10.1124/jpet.105.097618
    • Rezazadeh, S., Claydon, T. W., and Fedida, D. (2006). KN-93 (2-[N-(2-hydroxyethyl)]-N-(4-methoxybenzenesulfonyl)]amino-N-(4-chlorocinnamyl)-N-methylbenzylamine), a calcium/calmodulin-dependent protein kinase II inhibitor, is a direct extracellular blocker of voltage-gated potassium channels. J. Pharmacol. Exp. Ther. 317, 292-299. doi: 10.1124/jpet.105.097618.
    • (2006) J. Pharmacol. Exp. Ther. , vol.317 , pp. 292-299
    • Rezazadeh, S.1    Claydon, T.W.2    Fedida, D.3
  • 41
    • 0037307568 scopus 로고    scopus 로고
    • Modulation of the hyperpolarization-activated current (I(f)) by calcium and calmodulin in the guinea-pig sino-atrial node
    • doi: 10.1016/S0008-6363(02)00668-5
    • Rigg, L., Mattick, P. A., Heath, B. M., and Terrar, D. A. (2003). Modulation of the hyperpolarization-activated current (I(f)) by calcium and calmodulin in the guinea-pig sino-atrial node. Cardiovasc. Res. 57, 497-504. doi: 10.1016/S0008-6363(02)00668-5.
    • (2003) Cardiovasc. Res. , vol.57 , pp. 497-504
    • Rigg, L.1    Mattick, P.A.2    Heath, B.M.3    Terrar, D.A.4
  • 42
    • 0029741590 scopus 로고    scopus 로고
    • Possible role of calcium release from the sarcoplasmic reticulum in pacemaking in guinea-pig sino-atrial node
    • Rigg, L., and Terrar, D. A. (1996). Possible role of calcium release from the sarcoplasmic reticulum in pacemaking in guinea-pig sino-atrial node. Exp. Physiol. 81, 877-880.
    • (1996) Exp. Physiol. , vol.81 , pp. 877-880
    • Rigg, L.1    Terrar, D.A.2
  • 43
    • 33644701769 scopus 로고    scopus 로고
    • 2+ exchange for the pacemaking mechanism in guinea-pig sino-atrial node
    • doi: 10.1113/jphysiol.2005.100305
    • 2+ exchange for the pacemaking mechanism in guinea-pig sino-atrial node. J. Physiol. 571(Pt 3), 639-649. doi: 10.1113/jphysiol.2005.100305.
    • (2006) J. Physiol. , vol.571 , Issue.PART 3 , pp. 639-649
    • Sanders, L.1    Rakovic, S.2    Lowe, M.3    Mattick, P.A.4    Terrar, D.A.5
  • 44
    • 84883015458 scopus 로고    scopus 로고
    • CaMKII is essential for the proasthmatic effects of oxidation
    • doi: 10.1126/scitranslmed.3006135
    • Sanders, P. N., Koval, O. M., Jaffer, O. A., Prasad, A. M., Businga, T. R., Scott, J. A., et al. (2013). CaMKII is essential for the proasthmatic effects of oxidation. Sci. Transl. Med. 5, 195ra97. doi: 10.1126/scitranslmed.3006135.
    • (2013) Sci. Transl. Med. , vol.5 , pp. 195-197
    • Sanders, P.N.1    Koval, O.M.2    Jaffer, O.A.3    Prasad, A.M.4    Businga, T.R.5    Scott, J.A.6
  • 45
    • 0017854367 scopus 로고
    • Stimulation of brain membrane protein phosphorylation by calcium and an endogenous heat-stable protein
    • doi: 10.1038/271478a0
    • Schulman, H., and Greengard, P. (1978). Stimulation of brain membrane protein phosphorylation by calcium and an endogenous heat-stable protein. Nature 271, 478-479. doi: 10.1038/271478a0.
    • (1978) Nature , vol.271 , pp. 478-479
    • Schulman, H.1    Greengard, P.2
  • 46
    • 79961015131 scopus 로고    scopus 로고
    • Oxidized CaMKII causes cardiac sinus node dysfunction in mice
    • doi: 10.1172/JCI57833
    • Swaminathan, P. D., Purohit, A., Soni, S., Voigt, N., Singh, M. V., Glukhov, A. V., et al. (2011). Oxidized CaMKII causes cardiac sinus node dysfunction in mice. J. Clin. Invest. 121, 3277-3288. doi: 10.1172/JCI57833.
    • (2011) J. Clin. Invest. , vol.121 , pp. 3277-3288
    • Swaminathan, P.D.1    Purohit, A.2    Soni, S.3    Voigt, N.4    Singh, M.V.5    Glukhov, A.V.6
  • 47
    • 44349123473 scopus 로고    scopus 로고
    • Species difference in the contribution of T-type calcium current to cardiac pacemaking as revealed by r(-)-efonidipine
    • doi: 10.1254/jphs.SC0070405
    • Tanaka, H., Komikado, C., Namekata, I., Nakamura, H., Suzuki, M., Tsuneoka, Y., et al. (2008). Species difference in the contribution of T-type calcium current to cardiac pacemaking as revealed by r(-)-efonidipine. J. Pharmacol. Sci. 107, 99-102 doi: 10.1254/jphs.SC0070405.
    • (2008) J. Pharmacol. Sci. , vol.107 , pp. 99-102
    • Tanaka, H.1    Komikado, C.2    Namekata, I.3    Nakamura, H.4    Suzuki, M.5    Tsuneoka, Y.6
  • 48
    • 0034721798 scopus 로고    scopus 로고
    • Sinoatrial node pacemaker activity requires Ca (2+)/calmodulin-dependent protein kinase II activation
    • doi: 10.1161/01.RES.87.9.760
    • Vinogradova, T. M., Zhou, Y. Y., Bogdanov, K. Y., Yang, D., Kuschel, M., Cheng, H., et al. (2000). Sinoatrial node pacemaker activity requires Ca (2+)/calmodulin-dependent protein kinase II activation. Circ. Res. 87, 760-767. doi: 10.1161/01.RES.87.9.760.
    • (2000) Circ. Res. , vol.87 , pp. 760-767
    • Vinogradova, T.M.1    Zhou, Y.Y.2    Bogdanov, K.Y.3    Yang, D.4    Kuschel, M.5    Cheng, H.6
  • 49
    • 79952772425 scopus 로고    scopus 로고
    • Reactive oxygen species-activated Ca/calmodulin kinase IIδ is required for late I(Na) augmentation leading to cellular Na and Ca overload
    • doi: 10.1161/CIRCRESAHA.110.221911
    • Wagner, S., Ruff, H. M., Weber, S. L., Bellmann, S., Sowa, T., Schulte, T., et al. (2011). Reactive oxygen species-activated Ca/calmodulin kinase IIδ is required for late I(Na) augmentation leading to cellular Na and Ca overload. Circ. Res. 108, 555-565. doi: 10.1161/CIRCRESAHA.110.221911.
    • (2011) Circ. Res. , vol.108 , pp. 555-565
    • Wagner, S.1    Ruff, H.M.2    Weber, S.L.3    Bellmann, S.4    Sowa, T.5    Schulte, T.6
  • 50
    • 3042763171 scopus 로고    scopus 로고
    • 2+/calmodulindependent protein kinase II phosphorylation regulates the cardiac ryanodine receptor
    • doi: 10.1161/01.RES.0000125626.33738.E2
    • 2+/calmodulindependent protein kinase II phosphorylation regulates the cardiac ryanodine receptor. Circ. Res. 94, e61-e70. doi: 10.1161/01.RES.0000125626.33738.E2.
    • (2004) Circ. Res. , vol.94
    • Wehrens, X.H.1    Lehnart, S.E.2    Reiken, S.R.3    Marks, A.R.4
  • 51
    • 0025772161 scopus 로고
    • Unique phosphorylation site on the cardiac ryanodine receptor regulates calcium channel activity
    • Witcher, D. R., Kovacs, R. J., Schulman, H., Cefali, D. C., and Jones, L. R. (1991). Unique phosphorylation site on the cardiac ryanodine receptor regulates calcium channel activity. J. Biol. Chem. 266, 11144-11152.
    • (1991) J. Biol. Chem. , vol.266 , pp. 11144-11152
    • Witcher, D.R.1    Kovacs, R.J.2    Schulman, H.3    Cefali, D.C.4    Jones, L.R.5
  • 52
    • 65249100171 scopus 로고    scopus 로고
    • Calmodulin kinase II is required for fight or flight sinoatrial node physiology
    • doi: 10.1073/pnas.0806422106
    • Wu, Y., Gao, Z., Chen, B., Koval, O. M., Singh, M. V., Guan, X., et al. (2009). Calmodulin kinase II is required for fight or flight sinoatrial node physiology. Proc. Natl. Acad. Sci. U. S. A. 106, 5972-5977. doi: 10.1073/pnas.0806422106.
    • (2009) Proc. Natl. Acad. Sci. U. S. A. , vol.106 , pp. 5972-5977
    • Wu, Y.1    Gao, Z.2    Chen, B.3    Koval, O.M.4    Singh, M.V.5    Guan, X.6
  • 54
    • 77956640976 scopus 로고    scopus 로고
    • Alterations of L-type calcium current and cardiac function in CaMKII{delta} knockout mice
    • doi: 10.1161/CIRCRESAHA.110.222562
    • Xu, L., Lai, D., Cheng, J., Lim, H. J., Keskanokwong, T., Backs, J., et al. (2010). Alterations of L-type calcium current and cardiac function in CaMKII{delta} knockout mice. Circ. Res. 107, 398-407. doi: 10.1161/CIRCRESAHA.110.222562.
    • (2010) Circ. Res. , vol.107 , pp. 398-407
    • Xu, L.1    Lai, D.2    Cheng, J.3    Lim, H.J.4    Keskanokwong, T.5    Backs, J.6
  • 55
    • 84874522175 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent protein kinase II (CaMKII) activity and sinoatrial nodal pacemaker cell energetics
    • doi: 10.1371/journal.pone.0057079
    • 2+/calmodulin-dependent protein kinase II (CaMKII) activity and sinoatrial nodal pacemaker cell energetics. PLoS ONE 8:e57079. doi: 10.1371/journal.pone.0057079.
    • (2013) PLoS ONE , vol.8
    • Yaniv, Y.1    Spurgeon, H.A.2    Ziman, B.D.3    Lakatta, E.G.4
  • 57
    • 0027966195 scopus 로고
    • Ca-dependent facilitation of cardiac Ca current is due to Ca-calmodulin-dependent protein kinase
    • Yuan, W., and Bers, D. M. (1994). Ca-dependent facilitation of cardiac Ca current is due to Ca-calmodulin-dependent protein kinase. Am. J. Physiol. 267(3 Pt 2), H982-H993.
    • (1994) Am. J. Physiol. , vol.267 , Issue.3 PART 2
    • Yuan, W.1    Bers, D.M.2
  • 58
    • 20244362095 scopus 로고    scopus 로고
    • Calmodulin kinase II inhibition protects against structural heart disease
    • doi: 10.1038/nm1215
    • Zhang, R., Khoo, M. S., Wu, Y., Yang, Y., Grueter, C. E., Ni, G., et al. (2005). Calmodulin kinase II inhibition protects against structural heart disease. Nat. Med. 11, 409-417. doi: 10.1038/nm1215.
    • (2005) Nat. Med. , vol.11 , pp. 409-417
    • Zhang, R.1    Khoo, M.S.2    Wu, Y.3    Yang, Y.4    Grueter, C.E.5    Ni, G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.