A mechanism for tunable autoinhibition in the structure of a human Ca 2+/calmodulin-dependent kinase II holoenzyme

Cell

Volumn 146, Issue 5, 2011, Pages 732-745

  Chao, Luke H ^a,b   Stratton, Margaret M ^a,b   Lee, Il Hyung ^a,b   Rosenberg, Oren S ^a,b,f   Levitz, Joshua ^a   Mandell, Daniel J ^b,c   Kortemme, Tanja ^b,c   Groves, Jay T ^a,b,e   Schulman, Howard ^d   Kuriyan, John ^a,b,e  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d Allosteros Therapeutics   (United States)

^e LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II;

ARTICLE; BINDING SITE; COMPARATIVE STUDY; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME CONFORMATION; ENZYME INHIBITION; ENZYME REGULATION; ENZYME STRUCTURE; HUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN INTERACTION;

EID: 80052284705     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2011.07.038     Document Type: Article

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