Involvement of extrinsic and intrinsic apoptotic pathways together with endoplasmic reticulum stress in cell death induced by naphthylchalcones in a leukemic cell line: Advantages of multi-target action

Toxicology in Vitro

Volumn 28, Issue 5, 2014, Pages 769-777

  Winter, Evelyn ^a   Chiaradia, Louise Domeneghini ^a   Silva, Adny Henrique ^a   Nunes, Ricardo José ^a   Yunes, Rosendo Augusto ^a   Creczynski Pasa, Tânia Beatriz ^a  

^a FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

Author keywords

Chalcones; Endoplasmic reticulum; Extrinsic apoptosis; Intrinsic apoptosis; Leukemia

Indexed keywords

ANTINEOPLASTIC AGENT; CALCIUM; CASPASE 12; CASPASE 8; CASPASE 9; CYTOCHROME C; FAS ANTIGEN; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; NAPHTHYLCHALCONE R13; NAPHTHYLCHALCONE R15; NAPHTHYLCHALCONE R7; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BID; PROTEIN P21; PROTEIN P53; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; CHALCONE DERIVATIVE; CYCLIN DEPENDENT KINASE INHIBITOR 1A;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BAK GENE; BAX GENE; BCL2 GENE; CALCIUM CELL LEVEL; CANCER CELL DESTRUCTION; CELL CYCLE; CELL DEATH; CHOP GENE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG MECHANISM; DRUG STRUCTURE; ENDOPLASMIC RETICULUM STRESS; FAS GENE; GENE EXPRESSION; LEUKEMIA CELL; MITOCHONDRION; MOUSE; NONHUMAN; P21 GENE; P53 GENE; PROTEIN EXPRESSION; 3T3 CELL LINE; ANIMAL; DRUG EFFECTS; GENETICS; LEUKEMIA; METABOLISM; TUMOR CELL LINE; VERO CELL LINE;

ANIMALS; ANTIGENS, CD95; ANTINEOPLASTIC AGENTS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CALCIUM; CELL CYCLE; CELL DEATH; CELL LINE, TUMOR; CHALCONES; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYTOCHROMES C; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION; LEUKEMIA; MICE; NIH 3T3 CELLS; TUMOR SUPPRESSOR PROTEIN P53; VERO CELLS;

EID: 84897940926     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2014.02.002     Document Type: Article

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