-
1
-
-
12944271053
-
Cancer statistics, 2005
-
Jemal A., Murray T., Ward E., Samuels A., Tiwari R.C., Ghafoor A., Feuer E.J., and Thun M.J. Cancer statistics, 2005. CA Cancer J. Clin. 55 (2005) 10-30
-
(2005)
CA Cancer J. Clin.
, vol.55
, pp. 10-30
-
-
Jemal, A.1
Murray, T.2
Ward, E.3
Samuels, A.4
Tiwari, R.C.5
Ghafoor, A.6
Feuer, E.J.7
Thun, M.J.8
-
2
-
-
1542541519
-
Chemoprevention strategies using NSAIDs and COX-2 inhibitors
-
Keller J.J., and Giardiello F.M. Chemoprevention strategies using NSAIDs and COX-2 inhibitors. Cancer Biol. Ther. 2 (2003) S140-S149
-
(2003)
Cancer Biol. Ther.
, vol.2
-
-
Keller, J.J.1
Giardiello, F.M.2
-
3
-
-
1842531376
-
Celecoxib: a potent cyclooxygenase-2 inhibitor in cancer prevention
-
Kismet K., Akay M.T., Abbasoglu O., and Ercan A. Celecoxib: a potent cyclooxygenase-2 inhibitor in cancer prevention. Cancer Detect. Prev. 28 (2004) 127-142
-
(2004)
Cancer Detect. Prev.
, vol.28
, pp. 127-142
-
-
Kismet, K.1
Akay, M.T.2
Abbasoglu, O.3
Ercan, A.4
-
4
-
-
17744418769
-
The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis
-
Steinbach G., Lynch P.M., Phillips R.K., Wallace M.H., Hawk E., Gordon G.B., Wakabayashi N., Saunders B., Shen Y., Fujimura T., Su L.K., and Levin B. The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis. N. Engl. J. Med. 342 (2000) 1946-1952
-
(2000)
N. Engl. J. Med.
, vol.342
, pp. 1946-1952
-
-
Steinbach, G.1
Lynch, P.M.2
Phillips, R.K.3
Wallace, M.H.4
Hawk, E.5
Gordon, G.B.6
Wakabayashi, N.7
Saunders, B.8
Shen, Y.9
Fujimura, T.10
Su, L.K.11
Levin, B.12
-
5
-
-
10644257370
-
Death receptor regulation and celecoxib-induced apoptosis in human lung cancer cells
-
Liu X., Yue P., Zhou Z., Khuri F.R., and Sun S.Y. Death receptor regulation and celecoxib-induced apoptosis in human lung cancer cells. J. Natl. Cancer Inst. 96 (2004) 1769-1780
-
(2004)
J. Natl. Cancer Inst.
, vol.96
, pp. 1769-1780
-
-
Liu, X.1
Yue, P.2
Zhou, Z.3
Khuri, F.R.4
Sun, S.Y.5
-
6
-
-
11944270441
-
Celecoxib derivatives induce apoptosis via the disruption of mitochondrial membrane potential and activation of caspase 9
-
Ding H., Han C., Zhu J., Chen C.S., and D'Ambrosio S.M. Celecoxib derivatives induce apoptosis via the disruption of mitochondrial membrane potential and activation of caspase 9. Int. J. Cancer 113 (2005) 803-810
-
(2005)
Int. J. Cancer
, vol.113
, pp. 803-810
-
-
Ding, H.1
Han, C.2
Zhu, J.3
Chen, C.S.4
D'Ambrosio, S.M.5
-
7
-
-
18644380058
-
Cyclooxygenase-2 inhibitor celecoxib augments chemotherapeutic drug-induced apoptosis by enhancing activation of caspase-3 and -9 in prostate cancer cells
-
Dandekar D.S., Lopez M., Carey R.I., and Lokeshwar B.L. Cyclooxygenase-2 inhibitor celecoxib augments chemotherapeutic drug-induced apoptosis by enhancing activation of caspase-3 and -9 in prostate cancer cells. Int. J. Cancer 115 (2005) 484-492
-
(2005)
Int. J. Cancer
, vol.115
, pp. 484-492
-
-
Dandekar, D.S.1
Lopez, M.2
Carey, R.I.3
Lokeshwar, B.L.4
-
8
-
-
34250774915
-
Activation of p38 mitogen-activated protein kinase by celecoxib oppositely regulates survivin and gamma-H2AX in human colorectal cancer cells
-
Hsiao P.W., Chang C.C., Liu H.F., Tsai C.M., Chiu T.H., and Chao J.I. Activation of p38 mitogen-activated protein kinase by celecoxib oppositely regulates survivin and gamma-H2AX in human colorectal cancer cells. Toxicol. Appl. Pharmacol. 222 (2007) 97-104
-
(2007)
Toxicol. Appl. Pharmacol.
, vol.222
, pp. 97-104
-
-
Hsiao, P.W.1
Chang, C.C.2
Liu, H.F.3
Tsai, C.M.4
Chiu, T.H.5
Chao, J.I.6
-
9
-
-
0042697468
-
The JNK, ERK and p53 pathways play distinct roles in apoptosis mediated by the antitumor agents vinblastine, doxorubicin, and etoposide
-
Brantley-Finley C., Lyle C.S., Du L., Goodwin M.E., Hall T., Szwedo D., Kaushal G.P., and Chambers T.C. The JNK, ERK and p53 pathways play distinct roles in apoptosis mediated by the antitumor agents vinblastine, doxorubicin, and etoposide. Biochem. Pharmacol. 66 (2003) 459-469
-
(2003)
Biochem. Pharmacol.
, vol.66
, pp. 459-469
-
-
Brantley-Finley, C.1
Lyle, C.S.2
Du, L.3
Goodwin, M.E.4
Hall, T.5
Szwedo, D.6
Kaushal, G.P.7
Chambers, T.C.8
-
10
-
-
0029670589
-
p53 in signaling checkpoint arrest or apoptosis
-
Bates S., and Vousden K.H. p53 in signaling checkpoint arrest or apoptosis. Curr. Opin. Genet. Dev. 6 (1996) 12-18
-
(1996)
Curr. Opin. Genet. Dev.
, vol.6
, pp. 12-18
-
-
Bates, S.1
Vousden, K.H.2
-
11
-
-
0030941458
-
p53, the cellular gatekeeper for growth and division
-
Levine A.J. p53, the cellular gatekeeper for growth and division. Cell 88 (1997) 323-331
-
(1997)
Cell
, vol.88
, pp. 323-331
-
-
Levine, A.J.1
-
13
-
-
0033552640
-
Mechanisms of switching on p53: a role for covalent modification?
-
Meek D.W. Mechanisms of switching on p53: a role for covalent modification?. Oncogene 18 (1999) 7666-7675
-
(1999)
Oncogene
, vol.18
, pp. 7666-7675
-
-
Meek, D.W.1
-
14
-
-
0034664733
-
p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53
-
Oda K., Arakawa H., Tanaka T., Matsuda K., Tanikawa C., Mori T., Nishimori H., Tamai K., Tokino T., Nakamura Y., and Taya Y. p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53. Cell 102 (2000) 849-862
-
(2000)
Cell
, vol.102
, pp. 849-862
-
-
Oda, K.1
Arakawa, H.2
Tanaka, T.3
Matsuda, K.4
Tanikawa, C.5
Mori, T.6
Nishimori, H.7
Tamai, K.8
Tokino, T.9
Nakamura, Y.10
Taya, Y.11
-
15
-
-
0141733164
-
Phosphorylation site interdependence of human p53 post-translational modifications in response to stress
-
Saito S., Yamaguchi H., Higashimoto Y., Chao C., Xu Y., Fornace Jr. A.J., Appella E., and Anderson C.W. Phosphorylation site interdependence of human p53 post-translational modifications in response to stress. J. Biol. Chem. 278 (2003) 37536-37544
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 37536-37544
-
-
Saito, S.1
Yamaguchi, H.2
Higashimoto, Y.3
Chao, C.4
Xu, Y.5
Fornace Jr., A.J.6
Appella, E.7
Anderson, C.W.8
-
16
-
-
0035265686
-
PUMA, a novel proapoptotic gene, is induced by p53
-
Nakano K., and Vousden K.H. PUMA, a novel proapoptotic gene, is induced by p53. Mol. Cell 7 (2001) 683-694
-
(2001)
Mol. Cell
, vol.7
, pp. 683-694
-
-
Nakano, K.1
Vousden, K.H.2
-
17
-
-
33646741204
-
PUMA sensitizes lung cancer cells to chemotherapeutic agents and irradiation
-
Yu J., Yue W., Wu B., and Zhang L. PUMA sensitizes lung cancer cells to chemotherapeutic agents and irradiation. Clin. Cancer Res. 12 (2006) 2928-2936
-
(2006)
Clin. Cancer Res.
, vol.12
, pp. 2928-2936
-
-
Yu, J.1
Yue, W.2
Wu, B.3
Zhang, L.4
-
18
-
-
33750548225
-
Involvement of BH3-only proapoptotic proteins in mitochondrial-dependent phenoxodiol-induced apoptosis of human melanoma cells
-
Yu F., Watts R.N., Zhang X.D., Borrow J.M., and Hersey P. Involvement of BH3-only proapoptotic proteins in mitochondrial-dependent phenoxodiol-induced apoptosis of human melanoma cells. Anticancer Drugs 17 (2006) 1151-1161
-
(2006)
Anticancer Drugs
, vol.17
, pp. 1151-1161
-
-
Yu, F.1
Watts, R.N.2
Zhang, X.D.3
Borrow, J.M.4
Hersey, P.5
-
19
-
-
0030665678
-
Tumor suppressor p53 is a negative regulator in thyroid hormone receptor signaling pathways
-
Bhat M.K., Yu C., Yap N., Zhan Q., Hayashi Y., Seth P., and Cheng S. Tumor suppressor p53 is a negative regulator in thyroid hormone receptor signaling pathways. J. Biol. Chem. 272 (1997) 28989-28993
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 28989-28993
-
-
Bhat, M.K.1
Yu, C.2
Yap, N.3
Zhan, Q.4
Hayashi, Y.5
Seth, P.6
Cheng, S.7
-
20
-
-
0025152051
-
p53 mutations in colorectal cancer
-
Rodrigues N.R., Rowan A., Smith M.E., Kerr I.B., Bodmer W.F., Gannon J.V., and Lane D.P. p53 mutations in colorectal cancer. Proc. Natl. Acad. Sci. U.S.A. 87 (1990) 7555-7559
-
(1990)
Proc. Natl. Acad. Sci. U.S.A.
, vol.87
, pp. 7555-7559
-
-
Rodrigues, N.R.1
Rowan, A.2
Smith, M.E.3
Kerr, I.B.4
Bodmer, W.F.5
Gannon, J.V.6
Lane, D.P.7
-
21
-
-
30044435099
-
The blockage of survivin and securin expression increases the cytochalasin B-induced cell death and growth inhibition in human cancer cells
-
Chao J.I., and Liu H.F. The blockage of survivin and securin expression increases the cytochalasin B-induced cell death and growth inhibition in human cancer cells. Mol. Pharmacol. 69 (2006) 154-164
-
(2006)
Mol. Pharmacol.
, vol.69
, pp. 154-164
-
-
Chao, J.I.1
Liu, H.F.2
-
22
-
-
0033105947
-
Analysis of apoptosis by laser scanning cytometry
-
Bedner E., Li X., Gorczyca W., Melamed M.R., and Darzynkiewicz Z. Analysis of apoptosis by laser scanning cytometry. Cytometry 35 (1999) 181-195
-
(1999)
Cytometry
, vol.35
, pp. 181-195
-
-
Bedner, E.1
Li, X.2
Gorczyca, W.3
Melamed, M.R.4
Darzynkiewicz, Z.5
-
23
-
-
0033572746
-
Serine15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2
-
Dumaz N., and Meek D.W. Serine15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2. EMBO J. 18 (1999) 7002-7010
-
(1999)
EMBO J.
, vol.18
, pp. 7002-7010
-
-
Dumaz, N.1
Meek, D.W.2
-
24
-
-
0032484128
-
Phosphorylation of p53 serine 15 increases interaction with CBP
-
Lambert P.F., Kashanchi F., Radonovich M.F., Shiekhattar R., and Brady J.N. Phosphorylation of p53 serine 15 increases interaction with CBP. J. Biol. Chem. 273 (1998) 33048-33053
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 33048-33053
-
-
Lambert, P.F.1
Kashanchi, F.2
Radonovich, M.F.3
Shiekhattar, R.4
Brady, J.N.5
-
25
-
-
22544433198
-
Phosphorylation of human p53 at serine 46 determines promoter selection and whether apoptosis is attenuated or amplified
-
Mayo L.D., Seo Y.R., Jackson M.W., Smith M.L., Rivera Guzman J., Korgaonkar C.K., and Donner D.B. Phosphorylation of human p53 at serine 46 determines promoter selection and whether apoptosis is attenuated or amplified. J. Biol. Chem. 280 (2005) 25953-25959
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 25953-25959
-
-
Mayo, L.D.1
Seo, Y.R.2
Jackson, M.W.3
Smith, M.L.4
Rivera Guzman, J.5
Korgaonkar, C.K.6
Donner, D.B.7
-
26
-
-
4944255743
-
Post-translational modification of p53 in tumorigenesis
-
Bode A.M., and Dong Z. Post-translational modification of p53 in tumorigenesis. Nat. Rev. Cancer 4 (2004) 793-805
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 793-805
-
-
Bode, A.M.1
Dong, Z.2
-
28
-
-
0035400121
-
Dissipation of potassium and proton gradients inhibits mitochondrial hyperpolarization and cytochrome c release during neural apoptosis
-
Poppe M., Reimertz C., Dussmann H., Krohn A.J., Luetjens C.M., Bockelmann D., Nieminen A.L., Kogel D., and Prehn J.H. Dissipation of potassium and proton gradients inhibits mitochondrial hyperpolarization and cytochrome c release during neural apoptosis. J. Neurosci. 21 (2001) 4551-4563
-
(2001)
J. Neurosci.
, vol.21
, pp. 4551-4563
-
-
Poppe, M.1
Reimertz, C.2
Dussmann, H.3
Krohn, A.J.4
Luetjens, C.M.5
Bockelmann, D.6
Nieminen, A.L.7
Kogel, D.8
Prehn, J.H.9
-
29
-
-
0033179760
-
BCL-2 family members and the mitochondria in apoptosis
-
Gross A., McDonnell J.M., and Korsmeyer S.J. BCL-2 family members and the mitochondria in apoptosis. Genes Dev. 13 (1999) 1899-1911
-
(1999)
Genes Dev.
, vol.13
, pp. 1899-1911
-
-
Gross, A.1
McDonnell, J.M.2
Korsmeyer, S.J.3
-
30
-
-
38049144569
-
Celecoxib disrupts the canonical apoptotic network in HTLV-I cells through activation of Bax and inhibition of PKB/Akt
-
Sinha-Datta U., Taylor J.M., Brown M., and Nicot C. Celecoxib disrupts the canonical apoptotic network in HTLV-I cells through activation of Bax and inhibition of PKB/Akt. Apoptosis 13 (2008) 33-40
-
(2008)
Apoptosis
, vol.13
, pp. 33-40
-
-
Sinha-Datta, U.1
Taylor, J.M.2
Brown, M.3
Nicot, C.4
-
31
-
-
33947668865
-
Involvement of up-regulation of PUMA in non-steroidal anti-inflammatory drug-induced apoptosis
-
Ishihara T., Hoshino T., Namba T., Tanaka K., and Mizushima T. Involvement of up-regulation of PUMA in non-steroidal anti-inflammatory drug-induced apoptosis. Biochem. Biophys. Res. Commun. 356 (2007) 711-717
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.356
, pp. 711-717
-
-
Ishihara, T.1
Hoshino, T.2
Namba, T.3
Tanaka, K.4
Mizushima, T.5
-
32
-
-
0842278331
-
Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis
-
Chipuk J.E., Kuwana T., Bouchier-Hayes L., Droin N.M., Newmeyer D.D., Schuler M., and Green D.R. Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis. Science 303 (2004) 1010-1014
-
(2004)
Science
, vol.303
, pp. 1010-1014
-
-
Chipuk, J.E.1
Kuwana, T.2
Bouchier-Hayes, L.3
Droin, N.M.4
Newmeyer, D.D.5
Schuler, M.6
Green, D.R.7
-
33
-
-
1242271208
-
3-Phosphoinositide-dependent protein kinase-1/Akt signaling represents a major cyclooxygenase-2-independent target for celecoxib in prostate cancer cells
-
Kulp S.K., Yang Y.T., Hung C.C., Chen K.F., Lai J.P., Tseng P.H., Fowble J.W., Ward P.J., and Chen C.S. 3-Phosphoinositide-dependent protein kinase-1/Akt signaling represents a major cyclooxygenase-2-independent target for celecoxib in prostate cancer cells. Cancer Res. 64 (2004) 1444-1451
-
(2004)
Cancer Res.
, vol.64
, pp. 1444-1451
-
-
Kulp, S.K.1
Yang, Y.T.2
Hung, C.C.3
Chen, K.F.4
Lai, J.P.5
Tseng, P.H.6
Fowble, J.W.7
Ward, P.J.8
Chen, C.S.9
-
34
-
-
33745226982
-
Downregulation of survivin expression and concomitant induction of apoptosis by celecoxib and its non-cyclooxygenase-2-inhibitory analog, dimethyl-celecoxib (DMC), in tumor cells in vitro and in vivo
-
Pyrko P., Soriano N., Kardosh A., Liu Y.T., Uddin J., Petasis N.A., Hofman F.M., Chen C.S., Chen T.C., and Schonthal A.H. Downregulation of survivin expression and concomitant induction of apoptosis by celecoxib and its non-cyclooxygenase-2-inhibitory analog, dimethyl-celecoxib (DMC), in tumor cells in vitro and in vivo. Mol. Cancer 5 (2006) 19
-
(2006)
Mol. Cancer
, vol.5
, pp. 19
-
-
Pyrko, P.1
Soriano, N.2
Kardosh, A.3
Liu, Y.T.4
Uddin, J.5
Petasis, N.A.6
Hofman, F.M.7
Chen, C.S.8
Chen, T.C.9
Schonthal, A.H.10
-
35
-
-
1242271219
-
Cyclooxygenase-2 promotes human cholangiocarcinoma growth: evidence for cyclooxygenase-2-independent mechanism in celecoxib-mediated induction of p21waf1/cip1 and p27kip1 and cell cycle arrest
-
Han C., Leng J., Demetris A.J., and Wu T. Cyclooxygenase-2 promotes human cholangiocarcinoma growth: evidence for cyclooxygenase-2-independent mechanism in celecoxib-mediated induction of p21waf1/cip1 and p27kip1 and cell cycle arrest. Cancer Res. 64 (2004) 1369-1376
-
(2004)
Cancer Res.
, vol.64
, pp. 1369-1376
-
-
Han, C.1
Leng, J.2
Demetris, A.J.3
Wu, T.4
|