Matrix metalloproteinase (MMP)-9 in cancer-associated fibroblasts (CAFs) is suppressed by omega-3 polyunsaturated fatty acids in vitro and in vivo

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Taguchi, Ayumi ^a   Kawana, Kei ^a   Tomio, Kensuke ^a   Yamashita, Aki ^a   Isobe, Yosuke ^b   Nagasaka, Kazunori ^a   Koga, Kaori ^a   Inoue, Tomoko ^a   Nishida, Haruka ^a   Kojima, Satoko ^a   Adachi, Katsuyuki ^a   Matsumoto, Yoko ^a   Arimoto, Takahide ^a   Wada Hiraike, Osamu ^a   Oda, Katsutoshi ^a   Kang, Jing X ^c   Arai, Hiroyuki ^b   Arita, Makoto ^b   Osuga, Yutaka ^a   Fujii, Tomoyuki ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; GELATINASE B; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOLOGICAL ACTIVITY; CANCER ASSOCIATED FIBROBLAST; CANCER GROWTH; CARCINOGENESIS; CELL IMMORTALIZATION; CONTROLLED STUDY; DNA MICROARRAY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; ENZYME RELEASE; EPITHELIUM CELL; FAT INTAKE; FATTY ACID ANALYSIS; FEMALE; FIBROBLAST; IMMUNOREACTIVITY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIMARY CELL CULTURE; STROMA CELL; TUMOR MICROENVIRONMENT; TUMOR VOLUME; UTERINE CERVIX CANCER; WILD TYPE;

ANIMALS; CELL LINE, TRANSFORMED; CELL TRANSFORMATION, NEOPLASTIC; COCULTURE TECHNIQUES; DISEASE MODELS, ANIMAL; DOWN-REGULATION; FATTY ACIDS, OMEGA-3; FIBROBLASTS; GELATINASES; GENE EXPRESSION PROFILING; HUMANS; MATRIX METALLOPROTEINASE 9; MICE; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; TUMOR BURDEN;

EID: 84897825624     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0089605     Document Type: Article

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