-
1
-
-
33846227461
-
Constitutive histone H2AX phosphorylation and ATM activation are strongly amplified during mitogenic stimulation of lymphocytes
-
3860878, 17227291
-
Tanaka T, Kajstura M, Halicka HD, Traganos F, Darzynkiewicz Z. Constitutive histone H2AX phosphorylation and ATM activation are strongly amplified during mitogenic stimulation of lymphocytes. Cell Prolif 2007, 40:1-13. [http://dx.doi.org/10.1111/j.1365-2184.2007.00417.x], 3860878, 17227291.
-
(2007)
Cell Prolif
, vol.40
, pp. 1-13
-
-
Tanaka, T.1
Kajstura, M.2
Halicka, H.D.3
Traganos, F.4
Darzynkiewicz, Z.5
-
2
-
-
79952003900
-
DNA damage response in adult stem cells: pathways and consequences
-
10.1038/nrm3060, 21304553
-
Mandal PK, Blanpain C, Rossi DJ. DNA damage response in adult stem cells: pathways and consequences. Nat Rev Mol Cell Biol 2011, 12(3):198-202. [http://dx.doi.org/10.1038/nrm3060], 10.1038/nrm3060, 21304553.
-
(2011)
Nat Rev Mol Cell Biol
, vol.12
, Issue.3
, pp. 198-202
-
-
Mandal, P.K.1
Blanpain, C.2
Rossi, D.J.3
-
3
-
-
79952281751
-
53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress
-
10.1038/ncb2201, 21317883, Chan K L
-
Lukas C, Savic V, Bekker-Jensen S, Doil C, Neumann B, Pedersen RS, Grøfte M, Hickson ID, Bartek J, Lukas J, Chan K L 53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress. Nat Cell Biol 2011, 13(3):243-253. [http://dx.doi.org/10.1038/ncb2201], 10.1038/ncb2201, 21317883, Chan K L.
-
(2011)
Nat Cell Biol
, vol.13
, Issue.3
, pp. 243-253
-
-
Lukas, C.1
Savic, V.2
Bekker-Jensen, S.3
Doil, C.4
Neumann, B.5
Pedersen, R.S.6
Grøfte, M.7
Hickson, I.D.8
Bartek, J.9
Lukas, J.10
-
4
-
-
38049150586
-
The DNA damage response pathways: at the crossroad of protein modifications
-
10.1038/cr.2007.109, 18087291
-
Huen MSY, Chen J. The DNA damage response pathways: at the crossroad of protein modifications. Cell Res 2008, 18:8-16. [http://dx.doi.org/10.1038/cr.2007.109], 10.1038/cr.2007.109, 18087291.
-
(2008)
Cell Res
, vol.18
, pp. 8-16
-
-
Huen, M.S.Y.1
Chen, J.2
-
5
-
-
77952882508
-
The relevance of oxidative stress and cytotoxic DNA lesions for spontaneous mutagenesis in non-replicating yeast cells
-
Steinboeck F, Hubmann M, Bogusch A, Dorninger P, Lengheimer T, Heidenreich E. The relevance of oxidative stress and cytotoxic DNA lesions for spontaneous mutagenesis in non-replicating yeast cells. Mutat Res 2010, 688(1-2):47-52. [http://dx.doi.org/10.1016/j.mrfmmm.2010.03.006].
-
(2010)
Mutat Res
, vol.688
, Issue.1-2
, pp. 47-52
-
-
Steinboeck, F.1
Hubmann, M.2
Bogusch, A.3
Dorninger, P.4
Lengheimer, T.5
Heidenreich, E.6
-
6
-
-
77951942433
-
DNA binding cooperativity of p53 modulates the decision between cell-cycle arrest and apoptosis
-
10.1016/j.molcel.2010.02.037, 20471942
-
Schlereth K, Beinoraviciute-Kellner R, Zeitlinger MK, Bretz AC, Sauer M, Charles JP, Vogiatzi F, Leich E, Samans B, Eilers M, Kisker C, Rosenwald A, Stiewe T. DNA binding cooperativity of p53 modulates the decision between cell-cycle arrest and apoptosis. Mol Cell 2010, 38(3):356-368. [http://dx.doi.org/10.1016/j.molcel.2010.02.037], 10.1016/j.molcel.2010.02.037, 20471942.
-
(2010)
Mol Cell
, vol.38
, Issue.3
, pp. 356-368
-
-
Schlereth, K.1
Beinoraviciute-Kellner, R.2
Zeitlinger, M.K.3
Bretz, A.C.4
Sauer, M.5
Charles, J.P.6
Vogiatzi, F.7
Leich, E.8
Samans, B.9
Eilers, M.10
Kisker, C.11
Rosenwald, A.12
Stiewe, T.13
-
7
-
-
0034630432
-
Accumulation of short telomeres in human fibroblasts prior to replicative senescence
-
10.1006/excr.2000.4823, 10739676
-
Martens UM, Chavez EA, Poon SS, Schmoor C, Lansdorp PM. Accumulation of short telomeres in human fibroblasts prior to replicative senescence. Exp Cell Res 2000, 256:291-299. [http://dx.doi.org/10.1006/excr.2000.4823], 10.1006/excr.2000.4823, 10739676.
-
(2000)
Exp Cell Res
, vol.256
, pp. 291-299
-
-
Martens, U.M.1
Chavez, E.A.2
Poon, S.S.3
Schmoor, C.4
Lansdorp, P.M.5
-
8
-
-
0036139411
-
Modelling telomere shortening and the role of oxidative stress
-
10.1016/S0047-6374(01)00380-3, 11744046
-
Proctor CJ, Kirkwood TBL. Modelling telomere shortening and the role of oxidative stress. Mech Ageing Dev 2002, 123(4):351-363. 10.1016/S0047-6374(01)00380-3, 11744046.
-
(2002)
Mech Ageing Dev
, vol.123
, Issue.4
, pp. 351-363
-
-
Proctor, C.J.1
Kirkwood, T.B.L.2
-
9
-
-
0033954684
-
Accumulation of single-strand breaks is the major cause of telomere shortening in human fibroblasts
-
10.1016/S0891-5849(99)00207-5, 10656292
-
von Z, Pilger R, Sitte N. Accumulation of single-strand breaks is the major cause of telomere shortening in human fibroblasts. Free Radic Biol Med 2000, 28:64-74. 10.1016/S0891-5849(99)00207-5, 10656292.
-
(2000)
Free Radic Biol Med
, vol.28
, pp. 64-74
-
-
von, Z.1
Pilger, R.2
Sitte, N.3
-
10
-
-
50149090966
-
Variability and robustness in T cell activation from regulated heterogeneity in protein levels
-
10.1126/science.1158013, 2673522, 18719282
-
Feinerman O, Veiga J, Dorfman JR, Germain RN, Altan-Bonnet G. Variability and robustness in T cell activation from regulated heterogeneity in protein levels. Science 2008, 321(5892):1081-1084. [http://dx.doi.org/10.1126/science.1158013], 10.1126/science.1158013, 2673522, 18719282.
-
(2008)
Science
, vol.321
, Issue.5892
, pp. 1081-1084
-
-
Feinerman, O.1
Veiga, J.2
Dorfman, J.R.3
Germain, R.N.4
Altan-Bonnet, G.5
-
11
-
-
66249136447
-
Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis
-
10.1038/nature08012, 2858974, 19363473
-
Spencer SL, Gaudet S, Albeck JG, Burke JM, Sorger PK. Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis. Nature 2009, 459(7245):428-432. [http://dx.doi.org/10.1038/nature08012], 10.1038/nature08012, 2858974, 19363473.
-
(2009)
Nature
, vol.459
, Issue.7245
, pp. 428-432
-
-
Spencer, S.L.1
Gaudet, S.2
Albeck, J.G.3
Burke, J.M.4
Sorger, P.K.5
-
12
-
-
33749012528
-
Efficiency of carcinogenesis with and without a mutator mutation
-
10.1073/pnas.0606271103, 1599925, 16966602
-
Beckman RA, Loeb LA. Efficiency of carcinogenesis with and without a mutator mutation. Proc Nat Acad Sci USA 2006, 103(38):14140-14145. [http://dx.doi.org/10.1073/pnas.0606271103], 10.1073/pnas.0606271103, 1599925, 16966602.
-
(2006)
Proc Nat Acad Sci USA
, vol.103
, Issue.38
, pp. 14140-14145
-
-
Beckman, R.A.1
Loeb, L.A.2
-
13
-
-
0037202592
-
RecQ helicases and cellular responses to DNA damage
-
Wu L, Hickson ID. RecQ helicases and cellular responses to DNA damage. Mutat Res 2002, 509(1-2):35-47.
-
(2002)
Mutat Res
, vol.509
, Issue.1-2
, pp. 35-47
-
-
Wu, L.1
Hickson, I.D.2
-
14
-
-
35848949304
-
DNA damage response as an anti-cancer barrier: damage threshold and the concept of 'conditional haploinsufficiency'
-
10.4161/cc.6.19.4754, 17700066
-
Bartek J, Lukas J, Bartkova J. DNA damage response as an anti-cancer barrier: damage threshold and the concept of 'conditional haploinsufficiency'. Cell Cycle 2007, 6(19):2344-2347. 10.4161/cc.6.19.4754, 17700066.
-
(2007)
Cell Cycle
, vol.6
, Issue.19
, pp. 2344-2347
-
-
Bartek, J.1
Lukas, J.2
Bartkova, J.3
-
15
-
-
33847737716
-
DNA damage checkpoints: from initiation to recovery or adaptation
-
10.1016/j.ceb.2007.02.009, 17303408
-
Bartek J, Lukas J. DNA damage checkpoints: from initiation to recovery or adaptation. Curr Opin Cell Biol 2007, 19(2):238-245. [http://dx.doi.org/10.1016/j.ceb.2007.02.009], 10.1016/j.ceb.2007.02.009, 17303408.
-
(2007)
Curr Opin Cell Biol
, vol.19
, Issue.2
, pp. 238-245
-
-
Bartek, J.1
Lukas, J.2
-
17
-
-
2942627880
-
Mathematical modeling confirms the length-dependency of telomere shortening
-
10.1016/j.mad.2004.03.007, 15178133
-
op den Buijs J, van den Bosch PPJ, Musters MWJM, van Riel NAW. Mathematical modeling confirms the length-dependency of telomere shortening. Mech Ageing Dev 2004, 125(6):437-444. [http://dx.doi.org/10.1016/j.mad.2004.03.007], 10.1016/j.mad.2004.03.007, 15178133.
-
(2004)
Mech Ageing Dev
, vol.125
, Issue.6
, pp. 437-444
-
-
op den Buijs, J.1
van den Bosch, P.P.J.2
Musters, M.W.J.M.3
van Riel, N.A.W.4
-
18
-
-
77952527446
-
Telomere length trajectory and its determinants in persons with coronary artery disease: longitudinal findings from the heart and soul study
-
10.1371/journal.pone.0008612, 2797633, 20072607
-
Farzaneh-Far R, Lin J, Epel E, Lapham K, Blackburn E, Whooley MA. Telomere length trajectory and its determinants in persons with coronary artery disease: longitudinal findings from the heart and soul study. PLoS One 2010, 5:e8612. [http://dx.doi.org/10.1371/journal.pone.0008612], 10.1371/journal.pone.0008612, 2797633, 20072607.
-
(2010)
PLoS One
, vol.5
-
-
Farzaneh-Far, R.1
Lin, J.2
Epel, E.3
Lapham, K.4
Blackburn, E.5
Whooley, M.A.6
-
19
-
-
0035812845
-
The shortest telomere, not average telomere length, is critical for cell viability and chromosome stability
-
10.1016/S0092-8674(01)00504-9, 11595186
-
Hemann MT, Strong MA, Hao LY, Greider CW. The shortest telomere, not average telomere length, is critical for cell viability and chromosome stability. Cell 2001, 107:67-77. 10.1016/S0092-8674(01)00504-9, 11595186.
-
(2001)
Cell
, vol.107
, pp. 67-77
-
-
Hemann, M.T.1
Strong, M.A.2
Hao, L.Y.3
Greider, C.W.4
-
20
-
-
0344622606
-
The serial cultivation of human diploid cell strains
-
10.1016/0014-4827(61)90192-6, 13905658
-
Hayflick L, Moorhead P. The serial cultivation of human diploid cell strains. Exp Cell Res 1961, 25(3):585-621. [http://dx.doi.org/10.1016/0014-4827(61)90192-6], 10.1016/0014-4827(61)90192-6, 13905658.
-
(1961)
Exp Cell Res
, vol.25
, Issue.3
, pp. 585-621
-
-
Hayflick, L.1
Moorhead, P.2
-
21
-
-
0037687623
-
Alternative lengthening of telomeres, telomerase, and cancer
-
10.1016/S0304-3835(02)00702-4, 12757973
-
Reddel RR. Alternative lengthening of telomeres, telomerase, and cancer. Cancer Lett 2003, 194(2):155-162. 10.1016/S0304-3835(02)00702-4, 12757973.
-
(2003)
Cancer Lett
, vol.194
, Issue.2
, pp. 155-162
-
-
Reddel, R.R.1
-
22
-
-
34548508461
-
Aging and immortality in a cell proliferation model
-
10.1016/j.jtbi.2007.06.009, 2265559, 17631317
-
Antal T, Blagoev KB, Trugman SA, Redner S. Aging and immortality in a cell proliferation model. J Theor Biol 2007, 248(3):411-417. [http://dx.doi.org/10.1016/j.jtbi.2007.06.009], 10.1016/j.jtbi.2007.06.009, 2265559, 17631317.
-
(2007)
J Theor Biol
, vol.248
, Issue.3
, pp. 411-417
-
-
Antal, T.1
Blagoev, K.B.2
Trugman, S.A.3
Redner, S.4
-
23
-
-
24944460598
-
Shelterin: the protein complex that shapes and safeguards human telomeres
-
10.1101/gad.1346005, 16166375, de Lange T
-
de Lange T Shelterin: the protein complex that shapes and safeguards human telomeres. Genes Dev 2005, 19(18):2100-2110. [http://dx.doi.org/10.1101/gad.1346005], 10.1101/gad.1346005, 16166375, de Lange T.
-
(2005)
Genes Dev
, vol.19
, Issue.18
, pp. 2100-2110
-
-
-
24
-
-
0018890645
-
Intraclonal variation in proliferative potential of human diploid fibroblasts: stochastic mechanism for cellular aging
-
10.1126/science.7350644, 7350644
-
Smith JR, Whitney RG. Intraclonal variation in proliferative potential of human diploid fibroblasts: stochastic mechanism for cellular aging. Science 1980, 207(4426):82-84. 10.1126/science.7350644, 7350644.
-
(1980)
Science
, vol.207
, Issue.4426
, pp. 82-84
-
-
Smith, J.R.1
Whitney, R.G.2
-
25
-
-
34249028642
-
Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence
-
10.1371/journal.pbio.0050110, 1858712, 17472436
-
Passos JF, Saretzki G, Ahmed S, Nelson G, Richter T, Peters H, Wappler I, Birket MJ, Harold G, Schaeuble K, Birch-Machin MA, Kirkwood TBL, von Z. Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence. PLoS Biol 2007, 5(5):e110. [http://dx.doi.org/10.1371/journal.pbio.0050110], 10.1371/journal.pbio.0050110, 1858712, 17472436.
-
(2007)
PLoS Biol
, vol.5
, Issue.5
-
-
Passos, J.F.1
Saretzki, G.2
Ahmed, S.3
Nelson, G.4
Richter, T.5
Peters, H.6
Wappler, I.7
Birket, M.J.8
Harold, G.9
Schaeuble, K.10
Birch-Machin, M.A.11
Kirkwood, T.B.L.12
von, Z.13
-
26
-
-
38049057905
-
DNA damage in telomeres and mitochondria during cellular senescence: is there a connection?
-
10.1093/nar/gkm893, 2190715, 17986462
-
Passos JF, Saretzki G, von Zglinicki T. DNA damage in telomeres and mitochondria during cellular senescence: is there a connection?. Nucleic Acids Res 2007, 35(22):7505-7513. [http://dx.doi.org/10.1093/nar/gkm893], 10.1093/nar/gkm893, 2190715, 17986462.
-
(2007)
Nucleic Acids Res
, vol.35
, Issue.22
, pp. 7505-7513
-
-
Passos, J.F.1
Saretzki, G.2
von Zglinicki, T.3
-
27
-
-
0034992999
-
Stress, DNA damage and ageing - an integrative approach
-
10.1016/S0531-5565(01)00111-5, 11404050
-
von Z, Bürkle A, Kirkwood TB. Stress, DNA damage and ageing - an integrative approach. Exp Gerontol 2001, 36(7):1049-1062. 10.1016/S0531-5565(01)00111-5, 11404050.
-
(2001)
Exp Gerontol
, vol.36
, Issue.7
, pp. 1049-1062
-
-
von, Z.1
Bürkle, A.2
Kirkwood, T.B.3
-
28
-
-
0030666202
-
Individual beta-cells within the intact islet differentially respond to glucose
-
10.1074/jbc.272.42.26573, 9334237
-
de Vargas LM, Sobolewski J, Siegel R, Moss LG. Individual beta-cells within the intact islet differentially respond to glucose. J Biol Chem 1997, 272(42):26573-26577. [http://www.jbc.org/content/272/42/26573.abstract], 10.1074/jbc.272.42.26573, 9334237.
-
(1997)
J Biol Chem
, vol.272
, Issue.42
, pp. 26573-26577
-
-
de Vargas, L.M.1
Sobolewski, J.2
Siegel, R.3
Moss, L.G.4
-
29
-
-
33746367178
-
INOS-dependent DNA damage via NF-kappaB expression in hamsters infected with Opisthorchis viverrini and its suppression by the antihelminthic drug praziquantel
-
10.1002/ijc.21893, 16570287
-
Pinlaor S, Hiraku Y, Yongvanit P, Tada-Oikawa S, Ma N, Pinlaor P, Sithithaworn P, Sripa B, Murata M, Oikawa S, Kawanishi S. iNOS-dependent DNA damage via NF-kappaB expression in hamsters infected with Opisthorchis viverrini and its suppression by the antihelminthic drug praziquantel. Int J Cancer 2006, 119(5):1067-1072. [http://dx.doi.org/10.1002/ijc.21893], 10.1002/ijc.21893, 16570287.
-
(2006)
Int J Cancer
, vol.119
, Issue.5
, pp. 1067-1072
-
-
Pinlaor, S.1
Hiraku, Y.2
Yongvanit, P.3
Tada-Oikawa, S.4
Ma, N.5
Pinlaor, P.6
Sithithaworn, P.7
Sripa, B.8
Murata, M.9
Oikawa, S.10
Kawanishi, S.11
-
30
-
-
77954541844
-
Single-cell NF-kappaB dynamics reveal digital activation and analogue information processing
-
10.1038/nature09145, 3105528, 20581820
-
Tay S, Hughey JJ, Lee TK, Lipniacki T, Quake SR, Covert MW. Single-cell NF-kappaB dynamics reveal digital activation and analogue information processing. Nature 2010, 466(7303):267-271. [http://dx.doi.org/10.1038/nature09145], 10.1038/nature09145, 3105528, 20581820.
-
(2010)
Nature
, vol.466
, Issue.7303
, pp. 267-271
-
-
Tay, S.1
Hughey, J.J.2
Lee, T.K.3
Lipniacki, T.4
Quake, S.R.5
Covert, M.W.6
-
31
-
-
78951470515
-
Origins of regulated cell-to-cell variability
-
10.1038/nrm3044, 21224886
-
Snijder B, Pelkmans L. Origins of regulated cell-to-cell variability. Nat Rev Mol Cell Biol 2011, 12(2):119-125. [http://dx.doi.org/10.1038/nrm3044], 10.1038/nrm3044, 21224886.
-
(2011)
Nat Rev Mol Cell Biol
, vol.12
, Issue.2
, pp. 119-125
-
-
Snijder, B.1
Pelkmans, L.2
-
32
-
-
0034114544
-
Posttranslational modifications of p53 in replicative senescence overlapping but distinct from those induced by DNA damage
-
10.1128/MCB.20.8.2803-2808.2000, 85496, 10733583
-
Webley K, Bond JA, Jones CJ, Blaydes JP, Craig A, Hupp T, Wynford-Thomas D. Posttranslational modifications of p53 in replicative senescence overlapping but distinct from those induced by DNA damage. Mol Cell Biol 2000, 20(8):2803-2808. 10.1128/MCB.20.8.2803-2808.2000, 85496, 10733583.
-
(2000)
Mol Cell Biol
, vol.20
, Issue.8
, pp. 2803-2808
-
-
Webley, K.1
Bond, J.A.2
Jones, C.J.3
Blaydes, J.P.4
Craig, A.5
Hupp, T.6
Wynford-Thomas, D.7
|