-
1
-
-
0030983708
-
Mortality by cause for eight regions of the world: Global Burden of Disease Study
-
Murray, C.J. & Lopez, A.D. Mortality by cause for eight regions of the world: Global Burden of Disease Study. Lancet 349, 1269-1276 (1997).
-
(1997)
Lancet
, vol.349
, pp. 1269-1276
-
-
Murray, C.J.1
Lopez, A.D.2
-
2
-
-
33646799069
-
Global and regional burden of disease and risk factors 2001 systematic analysis of population health data
-
Lopez, A.D., Mathers, C.D., Ezzati, M., Jamison, D.T. & Murray, C.J. Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data. Lancet 367, 1747-1757 (2006).
-
(2006)
Lancet
, vol.367
, pp. 1747-1757
-
-
Lopez, A.D.1
Mathers, C.D.2
Ezzati, M.3
Jamison, D.T.4
Murray, C.J.5
-
3
-
-
0035891624
-
Sudden death due to cardiac arrhythmias
-
Huikuri, H.V., Castellanos, A. & Myerburg, R.J. Sudden death due to cardiac arrhythmias. N. Engl. J. Med. 345, 1473-1482 (2001).
-
(2001)
N. Engl. J. Med.
, vol.345
, pp. 1473-1482
-
-
Huikuri, H.V.1
Castellanos, A.2
Myerburg, R.J.3
-
4
-
-
56549109039
-
Genetic determinants of sudden cardiac death
-
Noseworthy, P.A. & Newton-Cheh, C. Genetic determinants of sudden cardiac death. Circulation 118, 1854-1863 (2008).
-
(2008)
Circulation
, vol.118
, pp. 1854-1863
-
-
Noseworthy, P.A.1
Newton-Cheh, C.2
-
5
-
-
39749149703
-
A genetic framework for improving arrhythmia therapy
-
Knollmann, B.C. & Roden, D.M. A genetic framework for improving arrhythmia therapy. Nature 451, 929-936 (2008).
-
(2008)
Nature
, vol.451
, pp. 929-936
-
-
Knollmann, B.C.1
Roden, D.M.2
-
6
-
-
60649118584
-
Development of a risk score for atrial fbrillation Framingham Heart Study): A community-based cohort study
-
Schnabel, R.B. et al. Development of a risk score for atrial fibrillation Framingham Heart Study): a community-based cohort study. Lancet 373, 739-745 (2009).
-
(2009)
Lancet
, vol.373
, pp. 739-745
-
-
Schnabel, R.B.1
-
7
-
-
4143131954
-
Electrocardiographic predictors of arrhythmic death and total mortality in the multicenter unsustained tachycardia trial
-
Zimetbaum, P.J. et al. Electrocardiographic predictors of arrhythmic death and total mortality in the multicenter unsustained tachycardia trial. Circulation 110, 766-769 (2004).
-
(2004)
Circulation
, vol.110
, pp. 766-769
-
-
Zimetbaum, P.J.1
-
8
-
-
0037426398
-
Prolonged QTc interval and high B-type natriuretic peptide levels together predict mortality in patients with advanced heart failure
-
Vrtovec, B. et al. Prolonged QTc interval and high B-type natriuretic peptide levels together predict mortality in patients with advanced heart failure. Circulation 107, 1764-1769 (2003).
-
(2003)
Circulation
, vol.107
, pp. 1764-1769
-
-
Vrtovec, B.1
-
9
-
-
0025990396
-
QT interval prolongation predicts cardiovascular mortality in an apparently healthy population
-
Schouten, E.G. et al. QT interval prolongation predicts cardiovascular mortality in an apparently healthy population. Circulation 84, 1516-1523 (1991).
-
(1991)
Circulation
, vol.84
, pp. 1516-1523
-
-
Schouten, E.G.1
-
10
-
-
27744474175
-
Responding to the threat of chronic diseases in India
-
Srinath Reddy, K., Shah, B., Varghese, C. & Ramadoss, A. Responding to the threat of chronic diseases in India. Lancet 366, 1744-1749 (2005).
-
(2005)
Lancet
, vol.366
, pp. 1744-1749
-
-
Srinath Reddy, K.1
Shah, B.2
Varghese, C.3
Ramadoss, A.4
-
11
-
-
0031569892
-
And characterization of a mouse sensory neuron tetrodotoxin-resistant voltage-gated sodium channel gene
-
Souslova, V.A., Fox, M., Wood, J.N. & Akopian, A.N. Cloning and characterization of a mouse sensory neuron tetrodotoxin-resistant voltage-gated sodium channel gene, Scn10a. Genomics 41, 201-209 (1997).
-
(1997)
Scn10a. Genomics
, vol.41
, pp. 201-209
-
-
Souslova, V.A.1
Fox, M.2
Wood, J.N.3
Cloning, N.A.A.4
-
12
-
-
0030041548
-
A tetrodotoxin-resistant voltage-gated sodium channel expressed by sensory neurons
-
Akopan, A.N., Sivilotti, L. & Wood, J.N. A tetrodotoxin-resistant voltage-gated sodium channel expressed by sensory neurons. Nature 379, 257-262 (1996).
-
(1996)
Nature
, vol.379
, pp. 257-262
-
-
Akopian, A.N.1
Sivilotti, L.2
Wood, J.N.3
-
13
-
-
34250306409
-
v1.8 is essential for pain at low temperatures
-
DOI 10.1038/nature05880, PII NATURE05880
-
Zimmermann, K. et al. Sensory neuron sodium channel Nav1.8 is essential for pain at low temperatures. Nature 447, 855-858 (2007). (Pubitemid 46920141)
-
(2007)
Nature
, vol.447
, Issue.7146
, pp. 855-858
-
-
Zimmermann, K.1
Leffler, A.2
Babes, A.3
Cendan, C.M.4
Carr, R.W.5
Kobayashi, J.-I.6
Nau, C.7
Wood, J.N.8
Reeh, P.W.9
-
14
-
-
0042977263
-
The TTX-resistant sodium channel Nav1.8 SNS/PN3) expression and correlation with membrane properties in rat nociceptive primary afferent neurons
-
Djouhri, L. et al. The TTX-resistant sodium channel Nav1.8 SNS/PN3): expression and correlation with membrane properties in rat nociceptive primary afferent neurons. J. Physiol. Lond.) 550, 739-752 (2003).
-
(2003)
J. Physiol. Lond.
, vol.550
, pp. 739-752
-
-
Djouhri, L.1
-
15
-
-
48749123103
-
The cell and molecular basis of mechanical, cold and infammatory pain
-
Abrahamsen, B. et al. The cell and molecular basis of mechanical, cold and infammatory pain. Science 321, 702-705 (2008).
-
(2008)
Science
, vol.321
, pp. 702-705
-
-
Abrahamsen, B.1
-
16
-
-
0033363999
-
The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathways
-
Akopian, A.N. et al. The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathways. Nat. Neurosci. 2, 541-548 (1999).
-
(1999)
Nat. Neurosci.
, vol.2
, pp. 541-548
-
-
Akopian, A.N.1
-
17
-
-
0034900781
-
Contribution of Na(v)1.8 sodium channels to action potential electrogenesis in DRG neurons
-
Renganathan, M., Cummins, T.R. & Waxman, S.G. Contribution of Na(v)1.8 sodium channels to action potential electrogenesis in DRG neurons. J. Neurophysiol. 86, 629-640 (2001).
-
(2001)
J. Neurophysiol.
, vol.86
, pp. 629-640
-
-
Renganathan, M.1
Cummins, T.R.2
Waxman, S.G.3
-
18
-
-
34250618329
-
Inactivation properties of sodium channel Nav1.8 maintain action potential amplitude in small DRG neurons in the context of depolarization
-
Patrick Harty, T. & Waxman, S.G. Inactivation properties of sodium channel Nav1.8 maintain action potential amplitude in small DRG neurons in the context of depolarization. Mol. Pain 3, 12 (2007).
-
(2007)
Mol. Pain
, vol.3
, pp. 12
-
-
Patrick Harty, T.1
Waxman, S.G.2
-
19
-
-
17144380822
-
The metabolic syndrome
-
Eckel, R.H., Grundy, S.M. & Zimmet, P.Z. The metabolic syndrome. Lancet 365, 1415-1428 (2005).
-
(2005)
Lancet
, vol.365
, pp. 1415-1428
-
-
Eckel, R.H.1
Grundy, S.M.2
Zimmet, P.Z.3
-
20
-
-
33748640974
-
Familial sudden death is an important risk factor for primary ventricular fbrillation: A case-control study in acute myocardial infarction patients
-
Dekker, L.R. et al. Familial sudden death is an important risk factor for primary ventricular fbrillation: a case-control study in acute myocardial infarction patients. Circulation 114, 1140-1145 (2006).
-
(2006)
Circulation
, vol.114
, pp. 1140-1145
-
-
Dekker, L.R.1
-
21
-
-
0033560866
-
CAMP-dependent phosphorylation of the tetrodotoxin-resistant voltage-dependent sodium channel SNS
-
DOI 10.1111/j.1469-7793.1999.0433v.x
-
Fitzgerald, E.M., Okuse, K., Wood, J.N., Dolphin, A.C. & Moss, S.J. cAMP-dependent phosphorylation of the tetrodotoxin-resistant voltage-dependent sodium channel SNS. J. Physiol. Lond.) 516, 433-446 (1999). (Pubitemid 29204448)
-
(1999)
Journal of Physiology
, vol.516
, Issue.2
, pp. 433-446
-
-
Fitzgerald, E.M.1
Okuse, K.2
Wood, J.N.3
Dolphin, A.C.4
Moss, S.J.5
-
22
-
-
33846863372
-
Effect of 8-bromo-cAMP on the tetrodotoxin-resistant sodium Nav 1.8) current in small-diameter nodose ganglion neurons
-
Matsumoto, S. et al. Effect of 8-bromo-cAMP on the tetrodotoxin-resistant sodiumNav 1.8) current in small-diameter nodose ganglion neurons. Neuropharmacology 52, 904-924 (2007).
-
(2007)
Neuropharmacology
, vol.52
, pp. 904-924
-
-
Matsumoto, S.1
-
23
-
-
2642536183
-
Novel isoforms of the sodium channels Nav1.8 and Nav1.5 are produced by a conserved mechanism in mouse and rat
-
Kerr, N.C., Holmes, F.E. & Wynick, D. Novel isoforms of the sodium channels Nav1.8 and Nav1.5 are produced by a conserved mechanism in mouse and rat. J. Biol. Chem. 279, 24826-24833 (2004).
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 24826-24833
-
-
Kerr, N.C.1
Holmes, F.E.2
Wynick, D.3
-
24
-
-
0037456077
-
Sensory neuron proteins interact with the intracellular domains of sodium channel NaV1.8. Brain Res
-
Malik-Hall, M., Poon, W.Y., Baker, M.D., Wood, J.N. & Okuse, K. Sensory neuron proteins interact with the intracellular domains of sodium channel NaV1.8. Brain Res. Mol. Brain Res. 110, 298-304 (2003).
-
(2003)
Mol. Brain Res.
, vol.110
, pp. 298-304
-
-
Malik-Hall, M.1
Poon, W.Y.2
Baker, M.D.3
Wood, J.N.4
Okuse, K.5
-
25
-
-
0035931932
-
A sodium-channel mutation causes isolated cardiac conduction disease
-
Tan, H.L. et al. A sodium-channel mutation causes isolated cardiac conduction disease. Nature 409, 1043-1047 (2001).
-
(2001)
Nature
, vol.409
, pp. 1043-1047
-
-
Tan, H.L.1
-
26
-
-
36048981858
-
Inherited arrhythmias: A National Heart, Lung, and Blood Institute and Offce of Rare Diseases workshop consensus report about the diagnosis, phenotyping, molecular mechanisms, and therapeutic approaches for primary cardiomyopathies of gene mutations affecting ion channel function
-
Lehnart, S.E. et al. Inherited arrhythmias: a National Heart, Lung, and Blood Institute and Offce of Rare Diseases workshop consensus report about the diagnosis, phenotyping, molecular mechanisms, and therapeutic approaches for primary cardiomyopathies of gene mutations affecting ion channel function. Circulation 116, 2325-2345 (2007).
-
(2007)
Circulation
, vol.116
, pp. 2325-2345
-
-
Lehnart, S.E.1
-
27
-
-
63449109595
-
Common variants at ten loci modulate the QT interval duration in the QTSCD Study
-
Pfeufer, A. et al. Common variants at ten loci modulate the QT interval duration in the QTSCD Study. Nat. Genet. 41, 407-414 (2009).
-
(2009)
Nat. Genet.
, vol.41
, pp. 407-414
-
-
Pfeufer, A.1
-
28
-
-
59949103364
-
Genome-wide association studies in an isolated founder population from the Pacifc Island of Kosrae
-
Lowe, J.K. et al. Genome-wide association studies in an isolated founder population from the Pacifc Island of Kosrae. PLoS Genet. 5, e1000365 (2009).
-
(2009)
PLoS Genet.
, vol.5
-
-
Lowe, J.K.1
-
29
-
-
63449136073
-
Common variants at ten loci infuence QT interval duration in the QTGEN Study
-
Newton-Cheh, C. et al. Common variants at ten loci infuence QT interval duration in the QTGEN Study. Nat. Genet. 41, 399-406 (2009).
-
(2009)
Nat. Genet.
, vol.41
, pp. 399-406
-
-
Newton-Cheh, C.1
-
30
-
-
44349166252
-
Common genetic variation near MC4R is associated with waist circumference and insulin resistance
-
Chambers, J.C. et al. Common genetic variation near MC4R is associated with waist circumference and insulin resistance. Nat. Genet. 40, 716-718 (2008).
-
(2008)
Nat. Genet.
, vol.40
, pp. 716-718
-
-
Chambers, J.C.1
-
31
-
-
33746512512
-
Principal components analysis corrects for stratifcation in genome-wide association studies
-
Price, A.L. et al. Principal components analysis corrects for stratifcation in genome-wide association studies. Nat. Genet. 38, 904-909 (2006).
-
(2006)
Nat. Genet.
, vol.38
, pp. 904-909
-
-
Price, A.L.1
-
32
-
-
43249125992
-
Estimation of the multiple testing burden for genomewide association studies of nearly all common variants
-
Pe'er, I., Yelensky, R., Altshuler, D. & Daly, M.J. Estimation of the multiple testing burden for genomewide association studies of nearly all common variants. Genet. Epidemiol. 32, 381-385 (2008).
-
(2008)
Genet. Epidemiol.
, vol.32
, pp. 381-385
-
-
Pe'Er, I.1
Yelensky, R.2
Altshuler, D.3
Daly, M.J.4
-
33
-
-
54449098592
-
Cytoskeletal protein 4.1R affects repolarization and regulates calcium handling in the heart
-
Stagg, M.A. et al. Cytoskeletal protein 4.1R affects repolarization and regulates calcium handling in the heart. Circ. Res. 103, 855-863 (2008).
-
(2008)
Circ. Res.
, vol.103
, pp. 855-863
-
-
Stagg, M.A.1
|