Inducible STAT3 NH2 terminal mono-ubiquitination promotes BRD4 complex formation to regulate apoptosis

Cellular Signalling

Volumn 26, Issue 7, 2014, Pages 1445-1455

  Ray, Sutapa ^a,b   Zhao, Yingxin ^a,b   Jamaluddin, Mohammad ^a   Edeh, Chukwudi B ^b   Lee, Chang ^b   Brasier, Allan R ^a,b  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^b University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Apoptosis; BRD4; Mono ubiquitination; Proliferation; STAT3

Indexed keywords

BROMODOMAIN CONTAINING PROTEIN 4; CYCLIN D1; LYSINE; MANGANESE SUPEROXIDE DISMUTASE; PROTEIN BCL 2; REGULATOR PROTEIN; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3; UNCLASSIFIED DRUG; (+)-JQ1 COMPOUND; AZEPINE DERIVATIVE; BRD4 PROTEIN, MOUSE; HYBRID PROTEIN; NUCLEAR PROTEIN; SOCS3 PROTEIN, MOUSE; STAT3 PROTEIN, MOUSE; SUPPRESSOR OF CYTOKINE SIGNALING; TRANSCRIPTION FACTOR; TRIAZOLE DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; UBIQUITIN;

APEX1 GENE; APOPTOSIS; ARTICLE; BCL2 GENE; BCL2L1 GENE; CCND1 GENE; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; COMPLEX FORMATION; CONTROLLED STUDY; EMBRYO; GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; ONCOGENE MYC; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; SOD2 GENE; SUPPRESSOR OF CYTOKINE SIGNALING 3 GENE; TRANSCRIPTION REGULATION; UBIQUITINATION; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CELL LINE; GENETIC TRANSCRIPTION; GENETICS; HEK293 CELL LINE; HEPG2 CELL LINE; METABOLISM; MOUSE; PROMOTER REGION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION;

ANIMALS; APOPTOSIS; AZEPINES; CELL LINE; CELL PROLIFERATION; HEK293 CELLS; HEP G2 CELLS; HUMANS; MICE; NUCLEAR PROTEINS; PROMOTER REGIONS, GENETIC; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION; TRIAZOLES; TUMOR NECROSIS FACTOR-ALPHA; UBIQUITIN; UBIQUITINATION;

EID: 84897486329     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2014.03.007     Document Type: Article

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