LFG-500 inhibits the invasion of cancer cells via down-regulation of PI3K/AKT/NF-κB signaling pathway

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Li, Chenglin ^a   Li, Fanni ^a   Zhao, Kai ^a   Yao, Jing ^a   Cheng, Yao ^a   Zhao, Li ^a   Li, Zhiyu ^a   Lu, Na ^a   Guo, Qinglong ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMETASTATIC AGENT; GELATINASE A; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LFG 500; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; STAT3 PROTEIN; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; FLAVONOID; LFG-500;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CARCINOMA; CANCER CELL CULTURE; CELL ADHESION; CELL MIGRATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LUNG METASTASIS; MALE; MELANOMA CELL; METASTASIS INHIBITION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TUMOR INVASION; ALLOGRAFT; ANIMAL; CELL MOTION; DRUG EFFECTS; ENZYME ACTIVATION; GENETICS; MELANOMA, EXPERIMENTAL; METABOLISM; PATHOLOGY; PROTEIN TRANSPORT; TRANSCRIPTION INITIATION; TUMOR CELL LINE; TUMOR VOLUME;

ALLOGRAFTS; ANIMALS; ANTINEOPLASTIC AGENTS; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; DOWN-REGULATION; ENZYME ACTIVATION; FLAVONOIDS; HUMANS; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MELANOMA, EXPERIMENTAL; MICE; NF-KAPPA B; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTIONAL ACTIVATION; TUMOR BURDEN;

EID: 84897483105     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0091332     Document Type: Article

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